Clinical trials: Bariatric Surgery Candidate
Asthma, Obesity
Contributing Factors in the Pathobiology of Airway Remodeling in Obesity
There are two aims for this study. The purpose of this study is to determine the effects of body weight and hormones on airway fibrosis (scarring) and lung function in obese \& lean asthma subjects compared to obese \& lean…
- Conditions
- Asthma, Obesity, Obesity, Morbid, Bariatric Surgery Candidate
- Trial name
- NCT03115632
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Duke University
Bariatric Surgery Candidate, Complication,Postoperative
Early Postoperative Complications in Patients Undergoing Bariatric Surgery
This study examined immediate postoperative complications in patients undergoing various bariatric surgeries, aiming to evaluate the safety and efficacy of these interventions.
- Trial name
- NCT06372912
- Testing
- Sleeve gastrectomy, Roux-en-Y gastric bypass, mini-gastric bypass, SADIS, intragastric balloon insertion, and gastric band placement are bariatric surgeries.
- Where
- Mexico
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Obesity, Anesthesia
Pre-oxygenation Methods in Bariatric Patients
The purpose of the study is to compare effectiveness of different methods of achieving pre-oxygenation in bariatric patients. The investigators intend to compare facemask pre-oxygenation with a high-flow humidified nasal oxygen.
- Conditions
- Obesity, Anesthesia, Bariatric Surgery Candidate
- Trial name
- NCT03428256
- Testing
- Optiflow and THRIVE technique, Standard anaesthetic face mask
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Bariatric Surgery Candidate, Pain, Postoperative
Efficacy of External Oblique Intercostal Block in Laparoscopic Bariatric Surgery
Laparoscopic bariatric procedures nowadays are employed under ERAS protocol as an ambulatory surgery. Pain after laparoscopic procedures arises significantly from port site incisions in the anterior abdominal wall, and shoulder…
- Conditions
- Bariatric Surgery Candidate, Pain, Postoperative, Narcotic Use, Analgesia
- Trial name
- NCT05592522
- Testing
- External oblique intercostal block, Oblique subcostal TAP block, Posterior Rectus sheath block
- Where
- Saudi Arabia
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Al Mashfa Medical Center
Bariatric Surgery Candidate, Postoperative Nausea and Vomiting
Prevention of Postoperative Nausea and Vomiting After Bariatric Surgery
Postoperative nausea and vomiting are common occurrences following bariatric surgery, occurring in up to 80% of patients and contributing to increased healthcare utilization and delays in discharge.
- Conditions
- Bariatric Surgery Candidate, Postoperative Nausea and Vomiting, Morbid Obesity
- Trial name
- NCT04644445
- Testing
- Bariatric Full Liquid Diet
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Bariatric Surgery Candidate
Does Antrum Size Matter in Sleeve Gastrectomy?
Laparoscopic sleeve gastrectomy (LSG) is currently the most frequent primary bariatric procedure performed worldwide. LSG is safe and effective in terms of excess weight loss.
- Trial name
- NCT04323072
- Testing
- Wide antrectomy, Smal antrectomy
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Overweight and Obesity, Bariatric Surgery Candidate
Protein Digestion After Bariatric Surgery in Older Adults
The goal of this clinical trial is to investigate protein digestibility after bariatric surgery. Does protein digestibility decrease after Roux-en-Y-Gastric Bypass? Does protein digestibility decrease after Sleeve Gastrectomy…
- Conditions
- Overweight and Obesity, Bariatric Surgery Candidate, Aging, Protein Malabsorption
- Trial name
- ProDigBO (NCT06076187)
- Testing
- Dual isotope protein digestibility method
- Where
- 2 sites in Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Bariatric Surgery Candidate
Endoscopic Management Of Refractory Gastro-cutaneous Fistula After Laparoscopic Sleeve Gastrectomy l
This study included patients who were admitted to investigators' center to do laparoscopic sleeve gastrectomy and complicated by gastro-cutaneous fistula . Cases were collected in the period from December 2019 to march 2021.
- Trial name
- NCT04879667
- Testing
- endoscopic management of gastrocutaneous fistula after laparoscopic sleeve gastrectomy
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Bariatric Surgery Candidate, Bariatric Surgical Procedure
Fat Taste Sensory Study
Fat is the most energy dense macronutrient and consuming fat has been positively correlated to obesity. Individuals afflicted with obesity crave fat more frequently, have a higher preference for fatty taste, and consume a higher…
- Trial name
- FaTSS (NCT03540693)
- Testing
- RYGB, SG, LAGB
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Bariatric Surgery Candidate, Perioperative Complication
Effects of Ondansetron, Metoclopramide and Granisetron on Perioperative Nausea and Vomiting in Patients Undergone Bariatric Surgery
Post-operative nausea and vomiting (PONV) is one of the leading causes of patient morbidity after laparoscopic bariatric surgeries.
- Conditions
- Bariatric Surgery Candidate, Perioperative Complication, Nausea, Vomiting, Postoperative
- Trial name
- PONV (NCT05087615)
- Testing
- Metoclopramide, Ondansetron, Metoclopramide and Ondanteron
- Where
- Iran
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Bariatric Surgery Candidate
DS vs SIPS-Bariatric Surgery Comparasion
The aim of this study is to answer the question of whether the single anastomosis, 300 cm loop, duodenal switch (SIPS) is an equally effective, safe, simpler operation with less nutritional and surgical risks than the standard…
- Trial name
- NCT03236142
- Testing
- SIPS Operation, Standard Duodenal Switch Operation
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Reading Health System
Obesity, Bariatric Surgery Candidate
Exploring the Effects of Obesity and Bariatric Surgery on the Brain Using Magnetic Resonance Imaging
Background and Purpose: The causes of obesity are highly complex, with eating behaviors playing a crucial role. Current research indicates that many brain regions are involved in the regulation of appetite, eating behaviors, and…
- Trial name
- NCT06708117
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Obesity, Morbid, Bariatric Surgery Candidate
Adipose Tissue Inflammation in Individuals Undergoing Bariatric Surgery
A growing body of work done over the past few decades has established that adipose tissue as an active endocrine organ which secretes a wide range of metabolic and immunological factors collectively called "adipokines (1)."…
- Trial name
- NCT03419273
- Testing
- bariatric surgery
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Mechanical Ventilation Pressure High, Bariatric Surgery Candidate
Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics
Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome).
- Trial name
- NCT06168162
- Testing
- titated PEEP to best static compliance
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obesity, Type2diabetes
Metabolic Effects of Bariatric Arterial Embolization vs Bariatric Surgery
Obesity and Type 2 diabetes mellitus (DMT2) are two of the most common chronic diseases of the Western society. Obesity is one critical factor in DMT2 development, with weight loss having profound beneficial effects on DMT2 and…
- Conditions
- Obesity, Type2diabetes, Bariatric Surgery Candidate, Metabolic Disease
- Trial name
- BEOD (NCT05859022)
- Testing
- Roux-en-Y gastric By-pass (RYGB) surgery, Bariatric Arterial Embolization (BAE) procedure
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Nova de Lisboa
Bariatric Surgery Candidate, Heart Failure
CV Imaging of Metabolic Interventions
Cardiovascular disease is the leading cause of death worldwide. It is becoming clearer that heart failure (HF) is closely associated with body's metabolism.
- Conditions
- Bariatric Surgery Candidate, Heart Failure, Cardiovascular Diseases
- Trial name
- CIRCMeta (NCT05650307)
- Testing
- MRI
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Morbid Obesity, Bariatric Surgery Candidate
EPO2-PV: Evaluation of Pre-Oxygenation Conditions in Morbidly Obese Volunteer: Effect of Position and Ventilation Mode
The risk of complications associated with airway management in obese patients is significant. The results of pre-oxygenation allow a prolonged non-hypoxic apnea time for the clinician.
- Trial name
- EPO2-PV (NCT02121808)
- Testing
- NIPPV, Tidal volume
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Laval University
Non-Alcoholic Steatohepatitis(NASH), Hepatitis C
Blood Collection Biorepository for Liver Disease Research
The purpose of establishing a biorepository is to provide high quality specimens (serum, plasma, buffy coat and liver tissue) for future researchers who are studying the effects that fatty liver and viral diseases have on the…
- Conditions
- Non-Alcoholic Steatohepatitis(NASH), Hepatitis C, Hepatitis B, Fibrosis
- Trial name
- NCT03025074
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Surgery, Bariatric Surgery Candidate
Magnetic System in Bariatric and General Surgery
Magnetic devices have been successfully used in bariatric surgery. To the date the only reported use of the magnet was for liver retraction.
- Trial name
- NCT04944810
- Testing
- Magnetic Gastric Bypass, Magnetic Sleeve Gastrectomy, Revisional Bariatric Surgery
- Where
- Venezuela
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Unidad Internacional de Cirugia Bariatrica y Metabolica
Type 1 Diabetes, Bariatric Surgery Candidate
Role of the Liver in Glucose Homeostasis Using Metabolic Imaging
The primary objective of this study is to assess hepatic glucose uptake using non-invasive metabolic imaging in three different populations that differ in terms of insulin and glucose kinetics.
- Trial name
- LEMON (NCT04352738)
- Testing
- Multiparametric, multinuclear MR (DMI/ 13C-MRS/ GlycoCEST/GlycoNOE)
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern