Clinical trials: Bariatric Surgical Procedure
Severe Obesity
Muscle Strength in Severe Obese Patients in the Postoperative of Bariatric Surgery
Excessive fat mass (FM) contributes to changes in the strength and endurance of skeletal muscles. Mid-thigh muscle mass is approximately 2.5 times that of fat mass, but individuals who are obese have increased intra- (fat within…
- Trial name
- NCT04129801
- Testing
- Isokinetic Dynamometer, Bioimpedance
- Where
- Brazil
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Roux en Y Gastric Bypass, Sleeve Gastrectomy
Venlafaxine PK Following Bariatric Surgery
This study is being conducted to evaluate how the body absorbs and processes the immediate release (IR) and sustained release (XR) medication venlafaxine (Effexor®).
- Trial name
- VLX (NCT02005107)
- Testing
- Venlafaxine IR and Venlafaxine XR
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- North Dakota State University
Obesity
The Impact of an Investment Based Intervention on Weight-loss and Beliefs About Food in Patients Post Bariatric Surgery
Although obesity surgery is currently the most effective method for achieving weight loss, not all patients lose the desired amount of weight and some show weight regain.
- Trial name
- NCT02045628
- Testing
- Investment intervention
- Where
- United Kingdom
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Bariatric Surgery
Rivaroxaban as Thrombosis Prophylaxis in Bariatric Surgery
The aim of this study is to investigate the efficacy and safety of rivaroxaban in obese patients undergoing bariatric surgery. The objectives are to assess the safety and feasibility of venous thromboembolism (VTE) prophylaxis…
- Trial name
- BARIVA (NCT03522259)
- Testing
- Rivaroxaban 10 MG Oral Tablet [Xarelto]
- Where
- 3 sites in Switzerland
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Sleeve Gastrectomy, External Oblique Intercostal Plane Block
Comparison of the Effects of External Oblique Intercostal Plane Block and Subcostal Transversus Plane Block Methods With Ultrasound Guidance on Postoperative Analgesia in Laparoscopic Sleeve Gastrectomy Operations
The primary aim of this study was to investigate the effects of the external oblique intercostal plane block and the subcostal transversus abdominis plane block on postoperative pain scores and opioid consumption in patients…
- Conditions
- Sleeve Gastrectomy, External Oblique Intercostal Plane Block, Subcostal Transverse Abdominis Plane Block
- Trial name
- NCT07547280
- Testing
- Ultrasound-guided external oblique intercostal plane block, Local anesthetic infiltration, Subcostal Transversus Abdominis Plane Block (s-TAP)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Education and Research Hospital
Weight, Physical Activity
A Virtual Support Pilot Program for Weight Loss Surgery Patients
Obesity affects over one-third of the US population, and is associated with serious medical problems like diabetes and heart disease.
- Trial name
- NCT01770366
- Testing
- Weight and Exercise Lifestyle Support (WELS), Usual Care
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
Morbid Obesity, Bariatric Surgery Candidate
Rivaroxaban Versus Enoxaparin for Prophylaxis of Venous Thromboembolism in Bariatric Surgery
Rivaroxaban versus enoxaparin for prophylaxis of venous thromboembolism in morbidly obese patients undergoing bariatric surgery: An open_label randomized controlled trial
- Trial name
- NCT06689241
- Testing
- Enoxaparin, rivaroxaban
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Bariatric Surgery Candidate
Erector Spinae Block and Transverse Abdominis Plane Block for Sleeve Gasterectomy
assess the efficacy of ultrasound guided erector spinae block to decrease the requirement for analgesics after laparoscopic sleeve gastrectomy and to decrease postoperative pain scores and opioid consumption compared to subcostal…
- Trial name
- NCT03747406
- Testing
- Erector spinae plane block, TAP block
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Dalia Ismail
Morbid Obesity
Nasal High Flow in Bariatric Surgery
High frequency nasal cannula (HFNC) provides an inspiration O2 fraction of 21-1% and it has a minimal dead space and can be well tolerated due to humidified air.
- Trial name
- NCT04048798
- Testing
- Oxygen therapy via HFNC, Oxygen therapy via face mask
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Bariatric Surgery Candidate, Morbid Obesity
Erector Spinae Plane Block Versus Opioid Based General Anesthesia During Laparoscopic Bariatric Surgery
bilateral continuous erector spinae plane blockade may represent a valuable alternatives to thoracіc epidurals analgaesіa in treatment of thoracic neuropathic pain.
- Conditions
- Bariatric Surgery Candidate, Morbid Obesity, Visceral Pain
- Trial name
- NCT03798522
- Testing
- bilateral ultrasound guided erector spinae plane block, Nalbuphine
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bariatric Surgery, Osteoporosis
Skeletal Health in Bariatric Surgery Patients
The investigators propose a prospective cohort trial that will help to understand the impact of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in pre- and post-menopausal female bariatric patients.
- Conditions
- Bariatric Surgery, Osteoporosis, Fractures, Bone, Roux En-Y Gastric Bypass
- Trial name
- NCT03331536
- Testing
- Roux en Y Gastric Bypass Pre-menopausal, Roux en Y Gastric Bypass Post-menopausal, Sleeve Gastrectomy Pre-menopausal
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity
Alcohol and Bariatric Surgery
The investigators wish to study the effects of alcohol on three forms of bariatric surgery, Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG) and laparoscopic adjustable gastric banding (LAGB) and compare them with a…
- Trial name
- ABS (NCT02766322)
- Testing
- Oral Alcohol challenge test Alcohol visit first, Intravenous Alcohol Challenge Test (Clamp), Intravenous Alcohol Self-administration Test
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Morbid Obesity, Overweight
Pharmacokinetics in Morbid Obesity After Bariatric Surgery
Morbid obesity (MO) is associated with several disorders such as hypertension, type 2 diabetes, dyslipemia and degenerative arthropathy that require pharmacological treatment.
- Trial name
- FAROBE/1 (NCT01086722)
- Testing
- "karolinska cocktail"
- Where
- 2 sites in Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Fundacion IMIM
Diabetes, Weightloss
The WISE (Weightloss Intervention Surgical Effects) Brain Study
This study is being done to learn about the changes that weight loss causes on brain function, memory and thinking ability in adults. The study does NOT cover any costs associated with bariatric surgery.
- Trial name
- WISEBrain (NCT02137070)
- Testing
- Bariatric Surgery Candidates, Non surgical/Community volunteers
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of Florida
Bariatric Surgery, Depression
Laughter Yoga Effect Depression, Serotonin Levels With Bariatric Surgery Patient
The goal of this a quasi-trial model with pre and post-test control group is to determine the effect of laughter yoga on depression and serotonin levels in patients undergoing bariatric surgery.
- Trial name
- NCT06020079
- Testing
- laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Diabetes Mellitus, Ketoacidosis
Expected Normal Ketone Values After Very Low and Bariatric Surgery
The investigators propose a multicenter prospective study in patients undergoing either an elective bariatric procedure or an elective benign procedure, including laparoscopic/open cholecystectomy, laparoscopic/open hiatus hernia…
- Trial name
- NCT05442918
- Where
- Australia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- St Vincent's Hospital Melbourne
Diabetes, Weight Loss
WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)
The goal of the study to understand the effects of weight loss and improvements in diabetes following bariatric surgery on brain function and thinking.
- Trial name
- NCT06861790
- Testing
- tVNS, Complete Vagotomy, Anterior Vagotomy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Florida
Weight Loss, Bariatric Surgery
Outcomes After Weight Loss Surgery in Low-Risk Patients
The purpose of this research is to determine patient-reported outcomes after weight loss surgery, including changes in health, mood, quality of life, health satisfaction, and emotional health, in low-risk patients.
- Trial name
- NCT05699083
- Testing
- Body Image/Self-Esteem Questionnaires
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr. Feiz & Associates
Bariatric Surgery, Lidocaine
Intravenous Lidocaine Infusion Versus Intravenous Dexmedetomidine Infusion During Sleeve Gastrectomy
Although laparoscopic (LAP) bariatric surgery is minimally invasive. Following any laparoscopic procedure, patients typically experience the peak of postoperative pain within the first 24 hours.
- Conditions
- Bariatric Surgery, Lidocaine, Dexmedetomidine
- Trial name
- NCT07327905
- Testing
- intravenous lidocaine, intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Obesity
Development of Obesity and Bariatric Surgery
This study focus on the cause of obesity and impacts of bariatric surgery on it.
- Trial name
- NCT03296605
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School