Clinical trials: Baseline
Competence
Live Supervision in Psychotherapy: Study Protocol for a Single Case Experimental Design Study (SCED)
Although clinical supervision is an essential part of psychotherapy training and development, the empirical evidence for effects on therapist competence and patient outcome is limited.
- Trial name
- NCT05612113
- Testing
- Live Supervision + Session Goal Formulation, Session Goal Formulation
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Karolinska Institutet
Sickle Cell Disease
A Study of SHP655 (rADAMTS13) in Sickle Cell Disease
TAK-755 (previously known as SHP655) is a medicine used to treat sickle cell disease (SCD). The main aim of the study is to measure the safety and tolerability of TAK-755 in SCD participants.
- Trial name
- RAISE (NCT03997760)
- Testing
- TAK-755
- Where
- 14 sites in United States
- Volunteers
- 19 people
- Sponsor
- Shire
Epilepsies, Partial
Vimpat® Added as Adjunctive Therapy to One Baseline Antiepileptic Drug
The purpose of this study is to systematically and prospectively collect data from patients with partial-onset seizures in routine clinical practice setting receiving adjunctive Vimpat®.
- Trial name
- VITOBA (NCT01098162)
- Where
- 113 sites in Germany
- Volunteers
- 576 people
- Sponsor
- UCB Pharma GmbH
Head and Neck Cancer
Sarcopenia in Head and Neck Cancer Patients Treated with Curative Hadrontherapy
The study focuses on the impact of sarcopenia on acute and late toxicities in head and neck tumor affected patients treated with particle therapy.
- Trial name
- NCT06207708
- Testing
- questionnaires QLQ-FA12, Mini Nutritional Assessment Short Form, Nutritional Risk Screening, diet questionnaire of frequency, ,body mass index measurement, blood biomarkers
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- CNAO National Center of Oncological Hadrontherapy
Renal Cell Carcinoma
Brivanib Metastatic Renal Cell Carcinoma
This is a phase II study of an investigational agent, brivanib, in patients with refractory metastatic renal cell carcinoma. This study will evaluate the safety and effectiveness of brivanib in renal cell carcinoma, and explore…
- Trial name
- NCT01253668
- Testing
- Brivanib alaninate, Polymerase chain reaction, Iodine I 124 chimeric monoclonal antibody G250
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Obesity
Obesity Childhood in Cuenca-Ecuador: Prevalence and Risk Factors
Hypothesis: Obesity in children of Cuenca is related with socioeconomical status and physical activity habits. Summary: The prevalence of obesity and overweigh in all age groups are increasing rapidly in the world.
- Trial name
- NCT01381978
- Where
- Ecuador
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Universidad de Cuenca
Cerebral Ischemia
Reversing Cerebral Oxygen Desaturations Greater That 10% of Baseline Values Using NIRS in the ICU
Study objectives: The main objective of this study is to determine the feasibility of implementing measures in the intensive care unit (ICU), based on a physiological algorithm, to reverse decreases in cerebral oxygen saturation…
- Trial name
- NIRS-ICU (NCT01875055)
- Testing
- NIRS and Algorithm, NIRS derived cerebral oximetry
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Manitoba
Yellow Fever (Healthy Volunteers), Biopsy/Methods
Baseline Assessment of Skin Resident Memory T Cells in Healthy Unvaccinated Participants
In The main GeKoSkimm trial (= A randomized controlled trial to compare the immunogenicity and skin imprinting of intradermal, subcutaneous and intramuscular yellow fever vaccination) the investigators try to understand whether…
- Trial name
- NCT07636551
- Testing
- Skin punch biopsy, Blood samples
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Heart Transplantation
Brachial Artery t-PA Release in Heart Transplant Recipients
Bradykinin stimulates t-PA release from intact vessels, but not from endothelial cells in culture. It has been proposed that the nerves of blood vessels are the source of bradykinin stimulated t-PA release.
- Trial name
- P1A3C (NCT00780637)
- Testing
- Bradykinin
- Where
- United States
- Sponsor
- Vanderbilt University
Maternal Malaria During Pregnancy - Baby Not Yet Delivered
Malaria Burden in Pregnant Women and the Incidence of Pregnancy in a Cohort of Nulligravida
The overarching aims of this study are to longitudinally determine the occurrence of pregnancy in a cohort of nulligravida at the community level and to estimate the burden of malaria infection during the course of the pregnancy…
- Trial name
- EPI-PAM (NCT06162078)
- Where
- Burkina Faso
- Volunteers
- 2,390 people, healthy volunteers welcome
- Sponsor
- Groupe de Recherche Action en Sante
Amenorrhea, Hypogonadotropic Hypogonadism
Baselines in Reproductive Disorders
The purpose of the study is to explore the way in which gonadotropins (pituitary hormones) are released into the body. The knowledge acquired in this study will be used for the diagnosis and treatment of reproductive endocrine…
- Conditions
- Amenorrhea, Hypogonadotropic Hypogonadism, Kallmann's Syndrome
- Trial name
- NCT00456274
- Testing
- Frequent baseline blood sampling
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Massachusetts General Hospital
Peripheral Angioplasty
Computer Prediction of Restenosis Following Peripheral Angioplasty
The purpose of this study is to develop a computer program that might be able to accurately assess the risk of artery re-narrowing following angioplasty or stenting based on computer images.
- Trial name
- NCT01202344
- Testing
- Additional x-ray images
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Dheeraj Rajan
Dyslipidemias
A Study Of Atorvastatin For The Treatment Of High Cholesterol In Patients At High Risk Of Coronary Heart Disease (CHD)
A study of the long-term (1 year) effectiveness of atorvastatin to keep patients of high cardiovascular risk at the LDL cholesterol goal of <115 mg/dL
- Trial name
- NCT00644709
- Testing
- Atorvastatin
- Where
- 15 sites in Belgium
- Volunteers
- 196 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Protoporphyria
Effect of Bitopertin on the Liver and on Levels of Protoporphyrin IX in Bile, Blood, Liver, and Stool in Patients With Erythropoietic Protoporphyria/X-linked Protoporphyria and Increased Liver Stiffness and/or Liver Enzymes at Baseline
The primary goal of this study is to assess safety and tolerability of bitopertin in subjects with Erythropoietic Protoporphyria (EPP) or X-linked Protoporphyria (XLP) and evidence of compensated liver disease.
- Trial name
- NCT07123363
- Testing
- bitopertin
- Sponsor
- Wake Forest University Health Sciences
Prostate Cancer, Metastatic Cancer
PSA Biochemical Response as Prognostic Factor in Metastatic Castration-Sensitive Prostate Cancer
Prostate cancer remains the most common malignancy in men in Europe. Over the last two decades, the treatment landscape for both localized and metastatic prostate cancer has been revolutionized.
- Conditions
- Prostate Cancer, Metastatic Cancer, Castrate Sensitive Prostate Cancer
- Trial name
- PSA-DEEP02 (NCT06652607)
- Testing
- Enzalutamide, Apalutamide (Erleada™) 60 mg or 240 mg tablets, Darolutamide (Nubeqa®) 300 mg tablets
- Where
- Italy
- Volunteers
- 152 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Vitamin D Deficiency, Covid19
Baseline Vitamin D Deficiency and COVID-19 Disease Severity
It is known that vitamin D has been found to decrease incidence of viral respiratory infections, as well as have effects on multiple cytokines involved in immunomodulation and the bradykinin/renin-angiotensin system.
- Trial name
- NCT04628000
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Parkview Medical Center
no Condition, Basic Science
OH Baseline Research Study
The One Health baseline research study is essential to comprehensively understand human, animal, and environmental health interrelation within Zambia's diverse ecosystems.
- Trial name
- OHS (NCT06904521)
- Where
- Zambia
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Personality Disorders
The Effects of Schema Therapy in Outpatient Forensic Mental Health Care: a Single Case Multiple-baseline Study.
Forensic psychiatry aims at reducing recidivism risk by treating mental or psychiatric problems. In forensic psychiatry approximately between 42 and 84% of the patients have PDs.
- Trial name
- STOFSCED (NCT05523544)
- Testing
- schematherapy
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- Vrije Universiteit Brussel
IVF, Ovarian Cysts
GnRH Antagonist Pre-treatment in the Early Follicular Phase for Resolution of a Baseline Functional Ovarian Cyst
In this study we would like to examine the effect of GnRH antagonist administration at the beginning of the follicular phase in patient presenting with a simple ovarian cyst 25-50 mm.
- Trial name
- NCT04993924
- Testing
- Cetrorelix Acetate, Ganerelix Acetate
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Assaf-Harofeh Medical Center
Inflammation, Iron Deficiency Anemias
Effect of Baseline Ferritin Level on Iron Status in Male Elite Youth Rowers
The data of 16 trained men from the Polish Youth National Rowing. All athletes presented as medically fit, with no underlying health problems.
- Conditions
- Inflammation, Iron Deficiency Anemias, Red Blood Cell
- Trial name
- NCT06878040
- Where
- Poland
- Volunteers
- 16 people
- Sponsor
- Poznan University of Physical Education