Clinical trials: Basic Physiology
Balance Disorders, Accidental Falls
Population Cohort Set-up for the Epidemiological Assessment of Balance Disorders in Elderly People
As people age, it becomes more common to experience balance problems. These issues can increase the risk of falling, which may lead to serious health consequences and loss of independence.
- Conditions
- Balance Disorders, Accidental Falls, Frailty, Aging
- Trial name
- EPIBAS (NCT06965660)
- Where
- Spain
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cerebral Microvascular Dysfunction, Cerebral Small Vessel Diseases
PRospective Observation on CErebral microvaScular Structure and Function
This is a population-based prospective cohort study, aiming to assess the prevalence, distributional characteristics, and dynamic change of cerebral small vessel dysfunction in a Chinese community population using advanced…
- Conditions
- Cerebral Microvascular Dysfunction, Cerebral Small Vessel Diseases, Cognitive Dysfunction, Cerebrovascular Disorders
- Trial name
- PROCESS (NCT06579677)
- Testing
- Without any intervention
- Where
- 2 sites in China
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Glaucoma
Does Glaucoma Cause Loss of Brain Function?
The purpose of the study is to determine if glaucoma is associated with neurodegenerative changes in areas of the brain other than the occipital lobe.
- Trial name
- NCT01303939
- Testing
- magnetic resonance imaging (MRI) of the brain
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Ageing, Mitochondrial Function
The Effect of Fish Oils With Dairy or Plant Based Lipids on Mitochondrial and Physical, and Cognitive Function, in Elderly Humans
The aim of this study is to determine whether dairy or plant based fats combined with fish oils can alter skeletal muscle mitochondrial, physical, and cognitive function.
- Conditions
- Ageing, Mitochondrial Function, Physical Function, Cognitive Function
- Trial name
- NCT04194983
- Testing
- Fish oils and dairy fat, Fish oils and plant fat
- Where
- 2 sites in Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Obesity, Functional Neuroimaging
Study on Brain Function of Obesity Classification
The purpose of this study was to investigate the differences and similarities of brain function in patients with four subtypes of obesity, and the relationship between brain function changes and complications after weight loss…
- Trial name
- NCT05892224
- Testing
- Laparoscopic sleeve gastrectomy
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Older Adults With Mild Neurocognitive Disorders, Older Adults With Non-communicable Diseases
Application of VR-based Working Memory Screening Test
We propose to validate an interactive, immersive spatial memory test from the laboratory test. This VR-based working memory test (VRWMT) is a first-person, self-pacing game embedded within a virtual reality environment, the…
- Conditions
- Older Adults With Mild Neurocognitive Disorders, Older Adults With Non-communicable Diseases, Healthy Age-matched Older Adults
- Trial name
- VR (NCT04600726)
- Testing
- no intervention
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Cognitive Reserve, Aging
Cognitive Reserve and Post-Fatigue Recovery in Older Adults
As people grow older, it is common to experience a drop in physical stamina and memory functions. This can make recovering from daily physical and mental fatigue more difficult, which directly impacts an individual's independent…
- Conditions
- Cognitive Reserve, Aging, Mental Fatigue, Fatigue
- Trial name
- NCT07667985
- Where
- Turkey (Türkiye)
- Volunteers
- 696 people, healthy volunteers welcome
- Sponsor
- Uşak University
Overweight and Obesity
EXerCise wEight Loss
The overall aim of this study is to investigate the effects of home-based resistance exercise programme on changes in body composition and strength during weight loss, in people living with obesity or overweight.
- Trial name
- EXCEL (NCT05702840)
- Testing
- Resistance exercise training + weight loss group, Weight loss only group (WL)
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Spinal Cord Injuries (SCI), Depression
Evaluation of a Home-based AOMI Intervention on Cognitive Function and Depression Among Adults With SCI
The investigators propose a pilot randomized clinical trial to determine if adults with spinal cord injury (SCI) show improved cognitive function and depression following home-based Action Observation and Motor Imagery (AOMI)…
- Conditions
- Spinal Cord Injuries (SCI), Depression, Motor Imagery, Cognitive Functions
- Trial name
- NCT06708026
- Testing
- Action Observation and Motor Imagery (AOMI) training, Basic wheelchair exercises, Watch landscape videos
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Air Pollution, mHealth Intervention
1/2- Bangladesh Center for Global Environmental and Occupational Health- Bangladesh
Almost 3 billion people worldwide, including 89% people in Bangladesh, are exposed to harmful household air pollutants (HAP) emitted from combustion of biomass (wood, agricultural residue, cow dung, etc.) fuel use for cooking.
- Conditions
- Air Pollution, mHealth Intervention, Cardiopulmonary Function, Immune Function
- Trial name
- GEOHealth-II (NCT05570552)
- Testing
- mHealth based behavioral change communication intervention
- Where
- Bangladesh
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Dynamic Q Angle and Core Endurance in Adolescent Athletes With Patellofemoral Pain Syndrome
This observational, cross-sectional study aimed to compare dynamic Q-angle, trunk/core endurance, and lower-extremity flexibility between elite adolescent female and male sprinters with and without patellofemoral pain syndrome…
- Trial name
- PFPS-QCORE (NCT07328750)
- Testing
- Patellofemoral Pain Syndrome Status
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Healthy
Digestion of Biopolymer Based Lipid Emulsions
In this randomized, double blind, unbalanced three way crossover trial, four lipid emulsions will be assessed on three study days.
- Trial name
- BioLE (NCT02865486)
- Testing
- Lipid emulsion
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Stroke
Efficacy of an Interactive Web-Based Home Therapy Program After Stroke
This is an online study that involves assessment and training of arm function at home. Stroke is the leading cause of disability worldwide.
- Trial name
- STRONG (NCT03484182)
- Testing
- Web-based Home Exercise Program, Standard Home Exercise Program
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Obesity, Neurofeedback
Real-time NIRS Neurofeedback Regulating Brain Cognitive Function in Obese Individuals
To determine the efficacy of real-time fNIRS neurofeedback for regulating the brain cognitive function in obese individuals.
- Trial name
- NCT04071717
- Testing
- NIRS neurofeedback
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Wu Wenjun-1
Hydrotherapy
Effects of Combining Eccentric and Aquatic Based Exercise on Muscle Function
The study will compare the effects of eccentric resistance training versus eccentric training combined with aquatic plyometric training on muscle function outcomes.
- Trial name
- NCT04977999
- Testing
- Exercise
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Brennan Thompson
Cognitive Change, Processing, Visual Spatial
Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Function
The investigators' study is designed to test whether brief exposure to a martial arts-based intervention (a coordinative, partnered training exercise known as "Hubod"), can improve cognitive function to a greater degree than…
- Conditions
- Cognitive Change, Processing, Visual Spatial, Inhibition (Psychology), Working Memory
- Trial name
- HUBOD (NCT04760054)
- Testing
- HUBOD, Active Comparator, Control Condition
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Obesity (BMI>30)
Machine Learning Prediction of Respiratory Muscle Changes and Ventilatory Responses After Incretin-Based Therapy in Obesity
This study aims to evaluate changes in respiratory function, respiratory muscle performance, and ventilatory responses following incretin-based therapy in individuals with obesity, and to identify predictors of these changes…
- Trial name
- NCT07663591
- Testing
- Incretin-based therapy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Biruni University
Adolescent Mental Health, Adolescent - Emotional Problem
A Validation Study of the Neuro-cognitive Emotion Monitoring-Intervention (NEMO-I) Application in Adolescents
This study aims to evaluate the validity and effectiveness of NEMO-I (Neuro-cognitive Emotion Monitoring-Intervention), a mobile application designed to help adolescents monitor and manage their cognitive and emotional…
- Conditions
- Adolescent Mental Health, Adolescent - Emotional Problem, Cognition Improvement
- Trial name
- NCT07700264
- Testing
- NEMO-I (Neuro-cognitive Emotion Monitoring-Intervention)
- Where
- South Korea
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Seoul Women's University
Physical Function in Older Adults
Application-Based Personalized Exercise Program in Older Adults
This study aims to evaluate the feasibility, usability, adherence, and potential effects of an application-based personalized multicomponent exercise program in older adults.
- Trial name
- NCT07872176
- Testing
- Application-Based Personalized Multicomponent Exercise Program
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Non-medicine Intervention
Research on Accurate Prediction of Long-term Medication Use for Schizophrenia Based on Cognitive Function
Chinese version of the cognitive function test of schizophrenia (MCCB) . To explore a predictive model for long-term medication use in patients based on cognitive function
- Trial name
- NCT04513275
- Testing
- non-medicine intervention
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center