Clinical trials: Basic Physiology
Infant Malnutrition, Malnutrition in Pregnancy
Supplementing Maternal and Infant Diet With High-energy, Micronutrient Fortified Lipid-based Nutrient Supplements (LNS)
The use of lipid-based nutrients (LNS), such as Nutributter or fortified spread (FS), have been associated with improved growth and development outcomes among infants in Ghana and Malawi.
- Trial name
- iLiNS-DYAD-M (NCT01239693)
- Testing
- IFA, MMN, LNS
- Where
- Malawi
- Volunteers
- 1,391 people, healthy volunteers welcome
- Sponsor
- Tampere University
Elderly Women
Effects of Water-based Aerobic and Combined Training in Elderly Woman
Purpose: Investigate neuromuscular, cardiorespiratory, functional capacity, quality of life and cognitive adaptations of eight weeks of water-based aerobic and combined training in elderly women previously trained for eight weeks…
- Trial name
- ACTIVE (NCT03892278)
- Testing
- Water-based aerobic training, Water-based aerobic and combined training, Control group
- Where
- Brazil
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Altitude Training Adaptation, Cognitive Function
Effects of Bicarbonate Spring Water Immersion on Cognitive Reliability and Post-Maximal Exercise Recovery in Adolescent Rowers During Altitude Training: A Sex-Stratified Three-Arm Randomized Controlled Trial
This randomized controlled trial aims to investigate the effects of hot spring bath therapy on cognitive function recovery, cerebral hemodynamics, and athletic performance in athletes undergoing altitude training.
- Conditions
- Altitude Training Adaptation, Cognitive Function, Cerebral Hemodynamics, Exercise Performance
- Trial name
- NCT07608913
- Testing
- Control Group：Natural Recovery, Hot water immersion group, hot spring immersion group
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Macao Polytechnic University
Ketosis, Ketonemia
Effects of Exogenous Ketosis on Renal Function, Renal Perfusion, and Sodium Excretory Capacity in Healthy Subjects
This is a randomized, placebo-controlled, double-blinded crossover design. Fifteen healthy subjects will be randomized to receive either ketone bodies (KE4) or placebo delivered by KetoneAid.
- Trial name
- KETO (NCT05980858)
- Testing
- Beta-hydroxybutyrate
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gødstrup Hospital
Hearing Loss, Sensorineural
PC-Based Rehabilitation of Auditory Function
Many older subjects experience difficulty in understanding speech in noisy environments. Part of this problem is related to changes that occur in the ear with age and compromise the hearing of high-pitched sounds.
- Trial name
- CINT (NCT00724347)
- Testing
- Consonant Identification Training
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Cognitive Ability, General
INSIGHT, A Comprehensive, Multidisciplinary Brain Training System
Adaptive reasoning and problem-solving are critical skills that allow for accurate decisions to be made based on varying levels of information.
- Trial name
- INSIGHT (NCT02780739)
- Testing
- Cognitive Training - 48 sessions, Fitness, Active Control
- Where
- United States
- Volunteers
- 521 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Sexual and Reproductive Health, Menopausal and Postmenopausal Women
THE EFFECT OF SEXUAL COUNSELING BASED ON THE EXPLISSIT MODEL ON SEXUAL FUNCTION, MARITAL ADJUSTMENT, AND QUALITY OF SEXUAL LIFE IN POSTMENOPAUSAL WOMEN
Sexual health is not merely about sexual dysfunction, but a complex, diverse, and multifaceted natural process encompassing a wide range of aspects of human life, extending from childhood to old age.
- Trial name
- NCT07559916
- Testing
- Group receiving sexual counseling based on the EX PLISSIT model.
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Motor Skills, Balance
Coordination-based Exercise Intervention in Preschool Children
This study intended to assess the impact of coordination-based exercise interventions on physical fitness, motor competence, and executive function among preschoolers aged 4 to 6 years.
- Conditions
- Motor Skills, Balance, Fitness, Preschool
- Trial name
- NCT06405854
- Testing
- Exercise
- Where
- Saudi Arabia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Princess Nourah Bint Abdulrahman University
Schizophrenia, Schizoaffective Disorder
Effects of Modafinil on Brain Function in Patients With Schizophrenia
This study will evaluate whether modafinil improves cognition in patients with schizophrenia and healthy volunteers. Modafinil is a drug that has been FDA approved for day-time sleepiness and allegedly increase the amount of the…
- Trial name
- NCT00057707
- Testing
- Modafinil, Functional MRI, Neuropsychological Testing
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Multiple Sclerosis
Improving Hand Movement and Coordination in People With Multiple Sclerosis Using Transcranial Magnetic Stimulation (TMS) and Muscle Electrostimulation (FES) To Support Manual Dexterity and Daily Function
The goal of this interventional study is to test whether combining transcranial magnetic stimulation (TMS) with functional electrical stimulation (FES) can improve hand and upper limb function in adults with Multiple Sclerosis…
- Trial name
- MANTRAStim (NCT07098273)
- Testing
- TMS and FES- based rehabilitation, FES-based rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Malnutrition, Diarrhea
WASH Benefits Kenya
The purpose of this study is to measure the independent and combined effects of interventions that improve sanitation, water quality, handwashing, and nutrition on child health and development in the first years of life.
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- WASHB-Kenya (NCT01704105)
- Testing
- Water Quality, Sanitation, Handwashing
- Where
- Kenya
- Volunteers
- 8,246 people, healthy volunteers welcome
- Sponsor
- Innovations for Poverty Action
Physical Activity
Understanding the Impact of School-Based Physical Activity Programs
The central hypothesis of the Fueling Learning Through Exercise (FLEX) study is two innovative school-based physical activity programs (a walking/running program and a classroom activity break program) will increase school-time…
- Trial name
- NCT02810834
- Testing
- Walking/Running program, Classroom physical activity break program
- Where
- United States
- Volunteers
- 1,182 people, healthy volunteers welcome
- Sponsor
- Tufts University
Cognitive Impairment
GAME Veterans With PTSD Using Computer-Based Cognitive Training
The investigators hypothesis are as follows: H1a: OEF/OIF veterans with PTSD who perform cognitive training (CT) will demonstrate greater objective improvements on standard (untrained) neurocognitive measures, with the largest…
- Trial name
- NCT01087775
- Testing
- Cognitive Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Karen Seal
Mindfulness, DNA Methylation
Effects of Mindfulness-based Intervention on Epigenetic Mechanisms, Cognition Function, Stress Response, and Well-being
The purpose of this study is to assess the effect of a mindfulness-based intervention on DNAmethylation, cognitive functions, stress response, and well-being in healthy female adults.
- Conditions
- Mindfulness, DNA Methylation, Learning and Memory, Stress
- Trial name
- NCT05085847
- Testing
- Mindfulness meditation training, Active control
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Malaria,Falciparum, Anemia in Children
Comparing Chemoprevention Drugs for School-based Malaria Control
This is an individually randomized, controlled, single blind three arm clinical trial of malaria chemoprevention strategies Arm 1: Intermittent preventive treatment with dihydroartemisinin-piperaquine (IPT-DP).
- Trial name
- NCT05980156
- Testing
- Dihydroartemisinin-Piperaquine, Chloroquine, Sulfadoxine pyrimethamine
- Where
- Malawi
- Volunteers
- 646 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Cognitive Function, Physical Function
Effects of Exercise Board Games on Cognitive Function in Older Adults
This study aims to evaluate the effects of an exercise-based board game intervention on cognitive function, physical function, and health promotion among community-dwelling older adults.
- Trial name
- NCT07586696
- Testing
- Exercise-Based Board Game Intervention
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Fall, Healthy Aging
Validity and Reliability of a Depth Camera-based Automated Physical Function and Fall Risk Assessments
Falls significantly reduce physical function as well as quality of life which leads to failure of successful aging among elders.
- Trial name
- NCT06519864
- Testing
- Azure Kinect-based Tandem Stance Test (ATST) and Physical Therapist's Measurements of Tandem Stance Test (PTST), Azure Kinect-based Five Times Sit-to-Stand Test (AFTSS) and Physical Therapist's Measurements of Five Times Sit-to-Stand Test (PFTSS), Azure Kinect-based Timed Up and Go Test (ATUG) and Physical Therapist's Measurements of Timed Up and Go Test (PTUG)
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sahmyook University
Sports Performance, Sports Nutritional Sciences
Effect of Infusion of Yerba Mate on Oxidative Stress, Physiology, and Performance of Trained Cyclists
This project comes forward with investigations regarding the use of yerba mate infusion in sports performance, providing new knowledge about the effects of its consumption on the performance of trained individuals, thus…
- Conditions
- Sports Performance, Sports Nutritional Sciences, Endurance Performance
- Trial name
- NCT04642144
- Testing
- Yerba mate infusion, Carbohydrate meal
- Where
- Brazil
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Catarina
Knee Osteoarthritis
Comparison of Aquatic and Land-Based Mulligan Mobilization With Movement in Knee Osteoarthritis
This study aims to compare the effects of aquatic and land-based Mulligan mobilization with movement in individuals with knee osteoarthritis, with particular focus on their impact on pain and functional outcomes.
- Trial name
- NCT07484529
- Testing
- Aquatic Mobilization with Movement, Land Mobilization with Movement
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Physical Activity
Supervised Group-based Walking Intervention Among Inactive Older Adults in Saudi Arabia
The purpose of the proposed study is to compare the effects of supervised group-based walking and non-supervised individual-based walking interventions on frailty, cognitive function and quality of life among inactive older…
- Trial name
- NCT05151575
- Testing
- supervised group-based walking and non-supervised individual-based walking interventions
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University