Clinical trials: Behavior, Adaptive
Emotional Regulation, Alcohol Drinking in College
Just-in-Time Coping Prompts for Reactive Digital Behavior in College Students
This study looks at the moments when college students feel a strong emotional swing, and how those moments relate to reacting online when upset, drinking alcohol, and eating in response to emotions.
- Conditions
- Emotional Regulation, Alcohol Drinking in College, Emotional Eating, Aggression
- Trial name
- REACT (NCT07789314)
- Testing
- Momentary coping prompt, Active control message
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Florida
Depression
An Adaptive Intervention for Depression Among Latinos Living With HIV
This study will use a pilot sequential multiple assignment randomized trial (SMART) design to build an adaptive treatment strategy (ATS) for depression and engagement in HIV among Latinos living with HIV.
- Trial name
- Latino-SMART (NCT03668379)
- Testing
- Augment w/mHealth, Maintenance, Switch to CBT & mHealth
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Educational Problems, Work-Related Condition
Intervention Program of a Job Crafting
The implementation of effective intervention programs is crucial in enhancing the overall well-being and performance of healthcare professionals, particularly in demanding environments such as nursing
- Conditions
- Educational Problems, Work-Related Condition, Nurse's Role
- Trial name
- JobCrafting (NCT06200701)
- Testing
- Job Crafting program
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Overweight and Obesity, Overweight
Precision Public Health: Enhancing Connections to Develop Just-in-Time Adaptive Intervention Strategies
The purpose of this pilot study is to examine the effects of different types of just-in-time intervention messages on daily meeting dietary, activity, and weighing goals in a sample of young adults participating in a mobile-based…
- Conditions
- Overweight and Obesity, Overweight, Obesity
- Trial name
- Nudge (NCT03836391)
- Testing
- Nudge
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Spinal Cord Injuries
Feasibility of the First Known Adaptive Intervention for People With SCI
The overall goal of the proposed research is to conduct a pilot study to test the feasibility and acceptability of a home-based exercise intervention (SMART-HEALTH).
- Trial name
- SMART-HEALTH (NCT04726891)
- Testing
- Movement-2-Music + Social Networking Support
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Exercise Training
Exercise-Induced Metabolic Compensation; a Physiological Adaptive Response to Exercise Training
The primary aim of this proposal is to identify changes in the volume of highly metabolic organs (liver, kidneys, and brain) that occur as a physiological adaptation to exercise training and lower the resting energy expenditure.
- Trial name
- NCT04460040
- Testing
- Exercise training
- Where
- Israel
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Low Vision
Wearable Echolocation Aids Using Parametric Sound
The objective of this study is to study a novel device designed to aid patients with impaired vision to safely navigate their environment.
- Trial name
- NCT07218991
- Testing
- Wearable Echolocation Device
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Stress, Psychological, Executive Functions
Adaptive Music Therapy for Psychosocial and Cognitive Functions of Older Adults
The proposed study is a pilot study that aims to understand if the Pi Electronics adaptive music intervention (AM) is effective to promote positive psychosocial and cognitive outcomes, over and above a traditional music…
- Conditions
- Stress, Psychological, Executive Functions, Loneliness, Emotion Regulation
- Trial name
- AMT (NCT05447312)
- Testing
- Adaptive Music Intervention, Traditional Music Intervention
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Diabetes, Depression
Diabetes and Depression Text Messaging Intervention
The main aim of the "Diabetes and Mental Health Adaptive Notification Tracking and Evaluation" trial (DIAMANTE) is to test a smartphone intervention that generates adaptive messaging, learning from daily patient data to…
- Conditions
- Diabetes, Depression, Physical Activity
- Trial name
- DIAMANTE (NCT03490253)
- Testing
- DIAMANTE Adaptive, DIAMANTE Static
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Work Related Stress, Psychologic Adaptation
CO-ADAPT: Adaptive Environments and Conversational Agent Based Approaches for Healthy Ageing and Work Ability
The purpose of this study is to identify effective methodologies to help people improve their ability to adapt to psychological stress.
- Trial name
- NCT04809090
- Testing
- SMT, App CA
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tommaso Ciulli
Aging, Metabolism
Practicality of Intermittent Fasting and Its Effect on Markers of Aging and Oxidative Stress
Healthy volunteers will be recruited to participate in a ten-week double-blinded crossover trial. The trial will consist of two, three-week periods of intermittent fasting, where subjects receive either antioxidant…
- Trial name
- NCT02132091
- Testing
- Intermittent Fasting, 400 IU Vitamin E, 1000 mg Vitamin C
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Florida
Physical Activity
An Adaptive Physical Activity Intervention for Overweight Adults
The purpose of this study is to develop and evaluate an adaptive shaping intervention based on Behavioral Economics and Operant principles to promote physical activity behaviors (adaptive group) and compare to a static physical…
- Trial name
- NCT01793064
- Testing
- Adaptive Intervention (AI), Static Intervention (SI)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Obsessive-Compulsive Disorder
Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder
This research study is for participants that have been diagnosed with intractable Obsessive -compulsive disorder (OCD). OCD is a persistent and oftentimes disabling disorder marked by unwanted and distressing thoughts…
- Trial name
- NCT04806516
- Testing
- Summit RC+S System with ECoG Paddles, One Month Blinded Discontinuation Period:
- Where
- 3 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
HIV, Substance Abuse Disorder
JomCare Study - A Harm Reduction Study
Chemsex, the use of psychoactive drugs before or during sexual activity, is a growing public health concern associated with striking increases in HIV, particularly among men who have sex with men (MSM).
- Trial name
- JomCare (NCT06794840)
- Testing
- JomCare is a smartphone-based just-in-time adaptive intervention (JITAI) for chemsex-related harm reduction.
- Where
- Malaysia
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Effects of Different Meals on the QT/QTc Interval, Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use
Food and Insulin Effect on QT/QTC Interval of ECG
Moxifloxacin is routinely used as a probe to confirm assay sensitivity in thorough electrocardiogram (ECG) studies. It has been shown that a meal shortens the QT interval, which may affect pharmacokinetics (PK) and/or…
- Conditions
- Effects of Different Meals on the QT/QTc Interval, Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use, C-Peptide Effects on the QT/QTc Interval, Moxifloxacin ECG Profile in Fed and Fasted State
- Trial name
- C11035 (NCT01642485)
- Testing
- Moxifloxacin 400 mg fasted, FDA breakfast, Continental breakfast
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Richmond Pharmacology Limited
Healthy Volunteer
Neural Mechanisms of Emotion-behaviour Interactions
Deciding what to do when for how long - self-organizing one's behaviour - is an important feature of daily life. Emotions arise providing short-cuts for the computational complexities.
- Trial name
- EMOBB (NCT07623746)
- Testing
- Functional Magnetic Resonance Imaging (fMRI)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Eating Behavior, Chronic Disease
JITAIs: Optimization of Effectiveness
The goal of this feasibility study is to get insight into the receptivity of a JITAI aimed at healthy dietary intake in inhabitants of a small city in the Netherlands.
- Trial name
- NCT05773625
- Testing
- Just-In-Time Adaptive Intervention
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Speech
Behavioral and Neural Characteristics of Adaptive Speech Motor Control
This study meets the NIH definition of a clinical trial, but is not a treatment study. Instead, the goal of this study is to investigate how hearing ourselves speak affects the planning and execution of speech movements.
- Trial name
- NCT06164717
- Testing
- Auditory feedback perturbation during speech, Visual feedback perturbation during reaching, DBS stimulation ON/OFF
- Where
- United States
- Volunteers
- 507 people, healthy volunteers welcome
- Sponsor
- University of Washington
Behavior, Adaptive, Mental Illness
IPS/Peer Support Intervention in the DTES
Individual placement support (IPS) is an evidence-based supported employment model for people with severe mental illness, designed to achieve employment in mainstream competitive jobs, either part-time or full-time.
- Conditions
- Behavior, Adaptive, Mental Illness, Substance Use
- Trial name
- NCT03748004
- Testing
- IPS/SP, WorkBC
- Where
- 3 sites in Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Violence, Domestic, Violence-Related Symptom
It's WeWomen Plus Intervention for Health, Safety and Empowerment
This study evaluates the impact of adaptive technology-based intervention (online, text and phone) "weWomenPlus" on safety, mental health and empowerment of abused immigrant women.
- Conditions
- Violence, Domestic, Violence-Related Symptom, Violence, Physical, Violence, Sexual
- Trial name
- IWWP (NCT04098276)
- Testing
- WeWomen Plus technology based intervention
- Where
- United States
- Volunteers
- 1,265 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University