Clinical trials: Behavior, Adaptive
HIV, Substance Abuse Disorder
JomCare Study - A Harm Reduction Study
Chemsex, the use of psychoactive drugs before or during sexual activity, is a growing public health concern associated with striking increases in HIV, particularly among men who have sex with men (MSM).
- Trial name
- JomCare (NCT06794840)
- Testing
- JomCare is a smartphone-based just-in-time adaptive intervention (JITAI) for chemsex-related harm reduction.
- Where
- Malaysia
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Behavior, Adaptive, Decision Analysis
Protocol Lab for Online Trial Delphi and Question Effects
This study nested as a randomized controlled trial within an online Delphi and will assess the impact of using different question section groupings to provide aggregate feedback to participants in an online Delphi study.
- Trial name
- NCT03498677
- Testing
- presentation order, alternative presentation order
- Where
- United Kingdom
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- ThinkWell
Behavior, Adaptive
The Prenatal/Early Infancy Project: An Adolescent Follow-up
The Nurse-Family Partnership, a program of prenatal and infancy home visiting by nurses, has been examined in a series of 3 randomized trials since 1977.
- Trial name
- NCT03079752
- Testing
- Developmental Screening, Screening plus Transportation, Screening, Transport, Prenatal Visits
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Schizophrenia, Schizoaffective Disorder
Decision-Making in Schizophrenia: A Combined Neuroimaging and Experience Sampling Study
The goal of this clinical trial is to learn if attention and ways of thinking impact decision-making and brain processes related to decision-making in people with schizophrenia or schizoaffective disorder relative to people…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Control Subjects
- Trial name
- NCT06745479
- Testing
- Positive Emotion Upregulation
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Delirium, Confusion
Intelligent Intensive Care Unit
Delirium, as a common complication of hospitalization, poses significant health problems in hospitalized patients. Though about a third of delirium cases can benefit from intervention, detecting and predicting delirium is still…
- Trial name
- ICU_Delirium (NCT02465307)
- Testing
- Confusion Assessment Method, Accelerometer, Commercially available camera
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Florida
Vaccination Refusal
An Adaptive Prenatal Intervention to Increase Childhood Vaccinations
This study will test whether proactively connecting expectant parents with factual vaccination information during pregnancy can build confidence in vaccinations and lead to timely vaccinations during pregnancy and once their…
- Trial name
- ADEPT (NCT05795855)
- Testing
- ADEPT
- Where
- United States
- Volunteers
- 770 people, healthy volunteers welcome
- Sponsor
- Emory University
Eating Behavior, Chronic Disease
JITAIs: Optimization of Effectiveness
The goal of this feasibility study is to get insight into the receptivity of a JITAI aimed at healthy dietary intake in inhabitants of a small city in the Netherlands.
- Trial name
- NCT05773625
- Testing
- Just-In-Time Adaptive Intervention
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Effects of Different Meals on the QT/QTc Interval, Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use
Food and Insulin Effect on QT/QTC Interval of ECG
Moxifloxacin is routinely used as a probe to confirm assay sensitivity in thorough electrocardiogram (ECG) studies. It has been shown that a meal shortens the QT interval, which may affect pharmacokinetics (PK) and/or…
- Conditions
- Effects of Different Meals on the QT/QTc Interval, Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use, C-Peptide Effects on the QT/QTc Interval, Moxifloxacin ECG Profile in Fed and Fasted State
- Trial name
- C11035 (NCT01642485)
- Testing
- Moxifloxacin 400 mg fasted, FDA breakfast, Continental breakfast
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Richmond Pharmacology Limited
Speech
Behavioral and Neural Characteristics of Adaptive Speech Motor Control
This study meets the NIH definition of a clinical trial, but is not a treatment study. Instead, the goal of this study is to investigate how hearing ourselves speak affects the planning and execution of speech movements.
- Trial name
- NCT06164717
- Testing
- Auditory feedback perturbation during speech, Visual feedback perturbation during reaching, DBS stimulation ON/OFF
- Where
- United States
- Volunteers
- 507 people, healthy volunteers welcome
- Sponsor
- University of Washington
Physical Activity
An Adaptive Physical Activity Intervention for Overweight Adults
The purpose of this study is to develop and evaluate an adaptive shaping intervention based on Behavioral Economics and Operant principles to promote physical activity behaviors (adaptive group) and compare to a static physical…
- Trial name
- NCT01793064
- Testing
- Adaptive Intervention (AI), Static Intervention (SI)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Healthy
Effects of Tai Chi Exercise on Innate and Adaptive Immune Function
Tai Chi is a traditional Chinese martial art that has been practiced for many centuries. Improvements in cardiorespiratory function, balance, muscular strength, flexibility in older subjects; preventing falls in the frail…
- Trial name
- NCT00172679
- Where
- 2 sites in Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Spinal Cord Injuries
Feasibility of the First Known Adaptive Intervention for People With SCI
The overall goal of the proposed research is to conduct a pilot study to test the feasibility and acceptability of a home-based exercise intervention (SMART-HEALTH).
- Trial name
- SMART-HEALTH (NCT04726891)
- Testing
- Movement-2-Music + Social Networking Support
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Substance Use
Developing a Digital Intervention to Prevent Risky Health Behaviors
The project will launch the development of Parents and Teens Together (PATT), a dyadic digital parent-teen prevention intervention, for families of young teens experimenting or at high risk for experimenting with substance use…
- Trial name
- PATT (NCT06538922)
- Testing
- Single Session Family Intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Physical Activity
Testing Adaptive Interventions to Improve Physical Activity for Sedentary Women
This study employs a Sequential Multiple Assignment Randomized Trial (SMART) and aims to determine the most effective adaptive intervention combining four efficacious treatments (enhanced physical activity monitor, motivational…
- Trial name
- NCT03558828
- Testing
- Step 1: PA Monitor, Step 1: PA Monitor + Text, Step 2: PA Monitor with Calls
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Aging
A New Adaptive Physical Activity Technology in Older Adults
The purpose of this study is to explore the feasibility and acceptability of a new physical activity technology (Jintronix) based on TV screen, virtual games and motion sensing cameras among pre-disabled older adults.
- Trial name
- Jintronix (NCT02467491)
- Testing
- Jintronix
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Florida
Health Behavior, Behavioral Activation
Mobile Behavioral Activation Program With Wearable Sensors and Secure Activity Verification
This study evaluates a mobile-integrated behavioral activation program designed to help adults improve their daily productivity, motivation, and task engagement.
- Conditions
- Health Behavior, Behavioral Activation, Sedentary Behavior
- Trial name
- MBAP-X (NCT07382804)
- Testing
- Behavioral: Mobile Behavioral Activation App, Mobile App + Wearable Activity Sensor, Mobile App + Wearable Sensor + Secure Activity Verification Layer
- Where
- United States
- Volunteers
- 227,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Healthy Lifestyle
STAR-C Digital Coaching Intervention
Objectives: The overall objective is to evaluate the effectiveness of the STAR-C digital coaching intervention for health-related lifestyle behavioural change.
- Trial name
- STAR-C (NCT05864001)
- Testing
- STAR-C mobile app
- Where
- Sweden
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Umeå University
Motivation, Physical Activity Promotion
Evaluating Mechanisms of Action of Adaptive Goal-Setting for Physical Activity
Behavior modification programs hold promise for increasing levels of physical activity (PA) for individuals who are insufficiently active.
- Conditions
- Motivation, Physical Activity Promotion, Behavior Change, Mobile Health
- Trial name
- NCT04505241
- Testing
- Remotely-delivered physical activity promotion
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Drexel University
Behavior, Adaptive, Mental Illness
IPS/Peer Support Intervention in the DTES
Individual placement support (IPS) is an evidence-based supported employment model for people with severe mental illness, designed to achieve employment in mainstream competitive jobs, either part-time or full-time.
- Conditions
- Behavior, Adaptive, Mental Illness, Substance Use
- Trial name
- NCT03748004
- Testing
- IPS/SP, WorkBC
- Where
- 3 sites in Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Contraception, Contraception Behavior
A Randomized-Controlled Trial to Increase the Uptake of LARCs in Cameroon
Cameroon exhibits a high and non-decreasing level of maternal mortality (roughly 600 per 100,000 live births), partially related to its relatively high total fertility rate (roughly 4.6).
- Conditions
- Contraception, Contraception Behavior, Contraceptive Usage, Contraceptive Method Switching
- Trial name
- HGOPY (NCT03733678)
- Testing
- Price discounts for SARCs, Price discounts for LARCs, Sequential vs. simultaneous recommendations
- Where
- Cameroon
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- World Bank