Clinical trials: Behavior And Behavior Mechanism
Alcohol Drinking
Effects of Topiramate on Adolescent Alcohol Use: Efficacy and Mechanisms
This study will help to determine whether the medication, topiramate, reduces alcohol use among adolescents with alcohol dependence.
- Trial name
- IMPACT (NCT01641445)
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Brown University
Appetitive Behavior
Scot Sweet Study (Interaction of a Non-nutritive Sweetener With a High-fibre Weight Loss Diet)
The investigators present a weight loss diet intervention study, to be conducted as a within-subject design, with all food and beverages provided, to assess interaction of non-nutritive sweetener (sucralose) with a high-fibre…
- Trial name
- SSS (NCT05892003)
- Testing
- Phase 1 Control, Phase 2 High Fibre Weight Loss, Phase 3 High Fibre and Non-Nutritive Sweetener Weight Loss
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Suicide
Neural Mechanisms and Predictors of an Ultra-Brief Suicide Prevention Strategy
The current study is a clinical trial, meaning a research study in which human subjects are prospectively assigned to one or more interventions to evaluate the effects of those interventions on health-related behavioral outcomes.
- Trial name
- NCT05275101
- Testing
- Crisis Response Planning, Crisis Risk Counseling
- Where
- United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Obesity, Gastric Emptying
Investigation of Neuro-hormonal Mechanisms of Hunger, Fullness and Obesity.
The purpose of this study is to determine abnormal neuro-hormonal mechanisms that may impair the ability to feel full and which therefore, may lead to obesity.
- Conditions
- Obesity, Gastric Emptying, Anxiety, Depression
- Trial name
- NCT01008371
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Irritable Bowel Syndrome (IBS), Anxiety
Anxiety and Depression in IBS: A Brain-Gut Axis Study
This study aims to understand how the gut and the brain communicate in people with Irritable Bowel Syndrome (IBS) who also experience anxiety and depression.
- Conditions
- Irritable Bowel Syndrome (IBS), Anxiety, Depression
- Trial name
- NCT07646834
- Testing
- Observational Study (No Intervention)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Myocardial Infarction, Arthritis
Mechanisms of Action of Acetaminophen
This research study investigates whether the ability of aspirin to reduce the risk of heart attacks may be diminished by the administration of acetaminophen.
- Trial name
- NCT00646906
- Testing
- Aspirin First, Aspirin Last, Acetaminophen 1000 mg/d
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Optical Phenomena
Attention Modulation of Local and Global Inhibition Mechanisms
Human behavior is both flexible and adapted to the environmental context through inhibition capabilities; the investigator control the subject's behavior by repressing inappropriate responses and selecting, among several…
- Trial name
- MILGattention (NCT04279158)
- Testing
- experience 1 "The negative priming task", experience 2 "Stop signal task", experience 3 "Anti-saccades"
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Gestational Diabetes Mellitus, Neurodevelopmental Disorders
n-3 PUFAs, Irisin and Maternal Glucose Metabolism From Pregnancy to Postpartum
This study aims to investigate the associations of maternal nutritional status during pregnancy and postpartum periods with postpartum abnormal glucose metabolism in Guangzhou pregnant women.
- Conditions
- Gestational Diabetes Mellitus, Neurodevelopmental Disorders, Postpartum Abnormal Glucose Metabolism, Child Growth and Development
- Trial name
- NCT03023293
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,122 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Respiratory Tract Infection, Smell Disorder
Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)
Background: Loss of the sense of smell can seriously affect a person's quality of life. The ability to smell can be damaged by many factors, including illnesses, injuries, and exposure to toxic chemicals.
- Conditions
- Respiratory Tract Infection, Smell Disorder, Influenza, Rhinosinusitis
- Trial name
- NCT07149428
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Primary Biliary Cholangitis (PBC)
RELIEF: Multimodal Prehabilitation to Treat Fatigue in Patients With Primary Biliary Cholangitis
The implementation of a non-pharmacological multimodal intervention program-including physical exercise, nutritional counseling, and psychological support-is expected to improve fatigue in patients with primary biliary…
- Trial name
- RELIEF (NCT07161245)
- Testing
- Multimodal prehabilitation, standard of care
- Where
- Spain
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Math Learning Disability, Child Development
Interventions in Mathematics and Cognitive Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities
- Trial name
- NCT05201534
- Testing
- Interventions in Mathematics and Cognitive Skills - Experimental, Interventions in Mathematics and Cognitive Skills - Active Comparator
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity, Appetitive Behavior
Regulation of Energy Balance and Metabolism - Mechanisms Behind and Beyond Obesity and Weight Loss
The study aims to investigate homeostatic and hedonic mechanisms regulating appetite, energy balance and metabolism in obesity and the effects of three distinct obesity treatments on these regulatory mechanisms.
- Trial name
- BALANCE (NCT03550339)
- Testing
- SURG, DIET, HAES
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Peripheral Arterial Disease
Local or Systemic Effects: Mechanisms Related to Arm Crank Exercise - Comparison Between Individuals With and Without PAD
INTRODUCTION: Exercise with an arm ergometer (EB) overcomes the main barrier to physical exercise in patients with Peripheral Artery Disease (PAD), leg pain during walking.
- Trial name
- NCT06828172
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Mental Health, Mindfulness
Perspective on Thoughts and Feelings as a Predictor of Psychological Well-being in Daily Life, in a Community Sample
This project examines the psychological construct of decentering - a mindfulness-related construct marked by an observer perspective on one's ongoing mental processes.
- Trial name
- NCT03336710
- Where
- United States
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
HIV, Depression
Stress and Pain in People Living With HIV
This is a basic human experimental study utilizing 4 groups of individuals with and without HIV and complex morbidities of cannabis use disorder and major depression who will participate in 2 sessions of the Yale Pain Stress Task…
- Conditions
- HIV, Depression, Cannabis Use Disorder, Stress
- Trial name
- HIV Stress (NCT06784908)
- Testing
- Yale Pain Stress Task (YPST)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University