Clinical trials: Behavioral Symptom
Chronic Pain, Opioid Use
Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients
This study is designed to find behavioral and neurophysiological correlates of pain avoidance behavior among chronic pain patients, controlling for risk for opioid use disorder.
- Trial name
- NCT04603417
- Testing
- Electroencephalography (EEG)/Magnetoencephalography (MEG)/MRI
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Frailty, Functional Decline
Exercise and Gezaixi Interventions on Community-Dwelling Older Adults
This interventional study evaluates a 12-week, once-weekly group exercise program combining 60 minutes of progressive strength training and 60 minutes of Taiwanese opera-based activities for community-dwelling adults aged ≥65 in…
- Conditions
- Frailty, Functional Decline, Community-Dwelling Older Adults
- Trial name
- NCT07302568
- Testing
- Strength Training plus Taiwanese Opera-based Activities
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Athletic Performance, Cognitive Fatigue
TCP-600 Supplementation and Performance Response in Professional Football Players
This study will examine whether a 28-day supplementation protocol containing taurine, caffeine, and phosphatidylserine can help professional male football players maintain physical performance, cognitive function…
- Conditions
- Athletic Performance, Cognitive Fatigue, Exercise Recovery, Football-Specific Performance
- Trial name
- TCP600-RESP (NCT07710547)
- Testing
- Taurine, Caffeine, Phosphatidylserine
- Where
- 3 sites in Poland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Vizja University in Warsaw
Periodontitis (Stage 3), Smoking ( Cigarette)
Salivary TNF-α, FoxO-1, and SIRT-1 Levels in Periodontitis and Smoking
This study examines whether smoking and gum disease (periodontitis) are linked to changes in three biological markers found in saliva: TNF-α, FoxO-1, and SIRT-1.
- Trial name
- NCT07764549
- Testing
- Salivary Biomarker Analysis (ELISA)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zehra Hasgül
Acute Pain
A Randomized Trial of Behavioral Economic Approaches to Reduce Unnecessary Opioid Prescribing
In this study, the investigators will evaluate the effect of a health system initiative aiming to change clinician opioid prescribing behaviors using two behavioral economic interventions - individual audit feedback and peer…
- Trial name
- REDUCE (NCT03825549)
- Testing
- Individual audit feedback, Peer comparison feedback
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Attention Deficit Disorder With Hyperactivity
Sleepiness and Driving Performances in Adults With Attention-Deficit/ Hyperactivity Disorder (ADHD)
The Attention Deficit/ Hyperactivity Disorder (ADHD) is a developmental disorder which affects 3 to 5 % of school age children. This disorder persists in the adulthood for 60 % of subjects.
- Trial name
- SOMTDA/H (NCT01160874)
- Testing
- Polysomnography, Maintenance Wakefulness Test, Neuropsychological evaluation
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Diarrhea, Acute Respiratory Infection
Oral Supplement for Pregnant and Lactating Mothers
To assess protection against early life infections through supplementation of mothers during pregnancy to the newborns' growth, morbidity, immune status intra and extra-uterine.
- Trial name
- NCT01073033
- Testing
- milk supplement 1, milk supplement 2
- Where
- Philippines
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Doomscrolling, Cyberchondriac Behavior
4-STEP-Training Program for Doomscrolling, Cyberchondriac Behavior and Psychiatric Symptoms (4-STEP-TPS) Among Individuals With Social Media Addiction
The goal of this clinical trial is to evaluate the effectiveness of the 4-Step Training Program for Social Media Addiction (4-STEP-TPS) in reducing social media addiction, doomscrolling, cyberchondriac behavior, depressive…
- Conditions
- Doomscrolling, Cyberchondriac Behavior, Social Media Addiction
- Trial name
- (4-STEP-TPS) (NCT07663708)
- Testing
- 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS)
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Obesity
Building Social Networks to Enhance Postpartum Weight Loss and Appropriate Infant Feeding Practices
The purpose of this study is to examine whether we can use social networks to spread health information and health behaviors that 1) support women in returning to their pre-pregnancy weight after delivery; and 2) promote healthy…
- Trial name
- NCT01081340
- Testing
- Social network building intervention, Home visit
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Weight Loss, Time Restricted Feeding
TRE: Microbiome, Metabolic Health and Bone
In the Time-Restricted Eating: Microbiome and Bone (TREMBO) study, the primary goal is to determine the effect of time-restricted eating with caloric restriction compared to caloric restriction alone on bone health, as well as…
- Conditions
- Weight Loss, Time Restricted Feeding, Bone Loss
- Trial name
- TREMBO (NCT05548517)
- Testing
- Time Restricted Eating (TRE), Calorie Restriction
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Exercise, Fatigue
Alterations in Gait, Strength, and Power After Ruck Marching
The purpose of this study is to determine change in injury risk and performance variables in males and females after walking unloaded and carrying a load with two different distributions (high-pack placement and mid-pack…
- Trial name
- SPARTAN (NCT05309603)
- Testing
- Loaded Walking High, Loaded Walking Mid, Walking
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Breast Neoplasm Female, Symptom Cluster
Effects of a Traditional Chinese Exercise Program on Symptom Cluster in Breast Cancer Patients
The Medical Research Council Framework for Developing and Evaluating Complex Interventions (MRC Framework) will be utilized to develop and evaluate an evidence-based tai chi intervention for managing the symptom cluster of…
- Conditions
- Breast Neoplasm Female, Symptom Cluster, Tai ji
- Trial name
- NCT04190342
- Testing
- control group, tai chi group
- Where
- 2 sites in China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Charles Darwin University
Healthy Participants, Anxiety Disorders (With High Anxiety Symptoms)
tVNS and Approach-Avoidance Behavior in Anhedonia and Anxiety
This study investigates if anhedonia and anxiety symptoms are associated with alterations in reinforcement learning, effort trade-offs for wins vs. punishments, and foraging behavior under threat.
- Conditions
- Healthy Participants, Anxiety Disorders (With High Anxiety Symptoms), Depressive Disorders (With High Anhedonia Symptoms), Comorbid Depression and Anxiety Disorder (With High Anhedonia and High Anxiety Symptoms)
- Trial name
- NCT07476469
- Testing
- tVNS
- Where
- Germany
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Dr. Nils B. Kroemer
Loneliness, Well-Being, Psychological
A Randomized Controlled Trial of Robotic Support for Enhanced Later Life (RoSELL)
The purpose of this study is to compare the efficacy of a personalized, co-designed robot interaction against a standardized, fixed robot interaction for reducing loneliness, depression, as well as improving self-agency and…
- Conditions
- Loneliness, Well-Being, Psychological, Depression - Major Depressive Disorder
- Trial name
- RoSELL (NCT07102017)
- Testing
- Co-Design LOVOT Intervention, Standard LOVOT Intervention
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Childhood Depression
Neural Mechanisms of Family-Focused Treatment for Youth Depression
The goal of this interventional study is to compare the baseline neural mechanisms and parenting in depressed and non-depressed children and to examine baseline neural mechanisms and parenting as predictors of Family-Focused…
- Trial name
- NCT06289010
- Testing
- Family-Focused Treatment for Childhood-Depression (FFT-CD)
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Depression, Anxiety
Virtual Mindfulness Intervention RCT
Mindfulness-based interventions (MBIs) have emerged as clinically effective interventions for anxiety, depression, and general distress.
- Trial name
- NCT05374213
- Testing
- Mindfulness-Based Intervention
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Chronic Disease, Risk Reduction
Rural Chronic Disease Risk Reduction
This study tests a web-based chronic disease risk reduction lifestyle medicine intervention among rural adults.
- Trial name
- NCT05611580
- Testing
- Chronic Disease Risk Reduction
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Florida State University
Burnout
Reducing Burnout Among Frontline Healthcare Workers During COVID-19
Physician burnout has a significant impact on the wellness and productivity of physicians as well as patient health outcomes. Managing burnout among frontline workers is critical to Canada's response to the COVID-19 pandemic, in…
- Trial name
- RESTORE (NCT04474080)
- Testing
- Virtual Peer Support Platform, Control Period
- Where
- Canada
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Iron Deficiency Anemia of Pregnancy
Adiposity and Iron Requirements in Pregnancy
This study aims to explore how body fat influences the response to either 25 or 50 mg of daily iron supplements during pregnancy.
- Trial name
- ADIPREG (NCT06425796)
- Testing
- Adiposity and Iron Requirements in Pregnancy (ADIPREG)
- Where
- 3 sites in United Kingdom
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Electric Stimulation Therapy, Obesity
Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
This study will determine whether electrical stimulation of an area of the brain called the dorsolateral prefrontal cortex, which is important in determining the feeling of fullness after eating, affects how much food a person…
- Conditions
- Electric Stimulation Therapy, Obesity, Weight Loss, Eating
- Trial name
- NCT00739362
- Testing
- Transcranial Direct Current Stimulation (TDCS)
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
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