Clinical trials: Behaviors
Tobacco Use Disorder, Schizophrenia
Nicotine and Sensorimotor Replacement for Smoking in Smokers With Schizophrenia
The objective of this study is to investigate the relative contributions of nicotine replacement and sensorimotor replacement (i.e., smoking denicotinized cigarettes) on abstinence-induced smoking urges, withdrawal-related…
- Trial name
- NCT01213524
- Testing
- sensorimotor replacement, 42 mg transdermal nicotine replacement, usual brand smoking
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Brown University
Acute Coronary Syndrome (ACS)
Improving Medication Adherence Through Graphically Enhanced Interventions in Acute Coronary Syndromes
Coronary heart disease (CHD) is the leading cause of death in the United States. Most people who die from CHD die of a heart attack.
- Trial name
- IMAGE-ACS (NCT00399880)
- Testing
- Health literacy intervention
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Vanderbilt University Medical Center
Insomnia Chronic
Effectiveness of BBT-I and Zopiclone for Chronic Insomnia
Background: Importance of chronic insomnia (CI) problem is determined by its high prevalence rate, comorbidity and resistance to the treatment.
- Trial name
- NCT03339583
- Testing
- Brief behavioral therapy, Zopiclone
- Volunteers
- 42 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Attention Deficit/Hyperactivity Disorder
The Effects of Vyvanse(TM) on Brain Hemodynamics and Reading
This is a single-blind, Investigator Initiated study to evaluate the safety and efficacy of Vyvanse™ and provide pilot data in two areas: (1) on the use of Near-Infrared Spectroscopy to detect medication effects in children with…
- Trial name
- VBHR (NCT00733356)
- Testing
- Vyvanse
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Kimberley Lakes
Smoking Cessation
Cognitive Remediation With D-Cycloserine
One hundred seventy-five eligible participants will be enrolled with aim of randomizing 60 to a double-blind, placebo-controlled trial of D-cycloserine added to cue-exposure treatment to prevent relapse to smoking.
- Trial name
- NCT01399866
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Vaping
Responses to E-cigarette Message Source and Presentation
The goal of this clinical trial is to use crowdsourcing to test the effects of a message source (expert and peer) and message presentation types (one-sided and two-sided) to identify the optimal message type for young adults who…
- Trial name
- NCT06274723
- Testing
- Expert, one-sided, Expert, two-sided, Peer, one-sided
- Where
- United States
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Attention Deficit Hyperactivity Disorder
Effectiveness and Duration of Effect of Open Treatment in Attention Deficit Hyperactivity Disorder (ADHD) Patients Treated With Lisdexamfetamine Dimesylate(Vyvanse)
The purpose of this study is to examine the effectiveness and length of effect of Vyvanse on lessening Attention-Deficit/Hyperactivity Disorder symptoms in adults.
- Trial name
- NCT01070394
- Testing
- LDX Treatment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Smoking
Utilizing Augmented Reality as an Adjunct for Smoking Cessation
The purpose of the study is to develop an preliminary test a tobacco smoking-related augmented reality (AR) paradigm for eventual development as an adjunctive tobacco cessation intervention.
- Trial name
- NCT04101422
- Testing
- Augmented Reality 1, Augmented Reality 2, Augmented Reality 3
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Depression
Org 24448 to Treat Major Depression
This study will evaluate the effectiveness of the experimental drug, Org 24448, for short-term treatment of depression. It will examine the effects of the drug on symptoms, such as low mood and persistent sadness, poor sleep and…
- Trial name
- NCT00113022
- Testing
- Org 24448
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- National Institute of Mental Health (NIMH)
Pathological Gambling
Topiramate in the Treatment of Pathological Gambling
This study will assess the efficacy of topiramate in the treatment of pathological gambling. Pathological gambling (PG) is a debilitating disorder, generally leading to severe personal, familial, financial, social, and…
- Trial name
- NCT00245583
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Heart Failure
Exercise and Cognitive Retraining to Improve Cognition in Heart Failure.
Cognitive impairment (CI) is a prevalent problem in persons with HF heart failure (HF) and is associated with adverse clinical outcomes, higher mortality and poorer quality of life.
- Trial name
- EXCITE (NCT02151266)
- Testing
- Exercise and Cognitive retraining, Exercise Only, Stretching and Flexibility
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Emory University
Acute Myocardial Infarction, Coronary Artery Disease
Myocardial Infarction, COmbined-device, Recovery Enhancement Study
Unplanned readmissions after hospitalization for acute myocardial infarction (AMI) are among the leading causes of preventable morbidity, mortality, and healthcare costs.
- Conditions
- Acute Myocardial Infarction, Coronary Artery Disease, Acute Coronary Syndrome, Myocardial Infarction
- Trial name
- MiCORE (NCT03760796)
- Testing
- Corrie Health Digital Platform
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins University
Trichotillomania
N-Acetyl Cysteine in Trichotillomania
This is a 12-week, double-blind study of N-Acetyl Cysteine in the treatment of trichotillomania
- Trial name
- NCT00354770
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Chicago
Depression
Paroxetine/Bupropion in Suicide Attempters/Ideators With Major Depression
The primary study comparing effectiveness for suicidal ideation and/or behavior of two antidepressant medications in depressed patients who have attempted suicide or are currently experiencing suicidal thoughts has been…
- Trial name
- NCT00429169
- Testing
- Paroxetine, Bupropion
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- New York State Psychiatric Institute
Dyslipidemias
Effect of Vitamin D Supplementation on Exercise Adaptations in Patients on Statin Therapy
Statins along with lifestyle modifications including exercise are commonly prescribed to patients with type 2 diabetes. American diabetes association recommends using moderate-intensity statin and lifestyle therapy for patients…
- Trial name
- NCT02030041
- Testing
- Vitamin D, Simvastatin
- Where
- India
- Volunteers
- 33 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Breast Feeding
Newborn Feeding and Infant Phenotype
Breast feeding is believed to be beneficial to long-term health but how these effects are mediated is unknown. I suggest that this may be through effects on body composition and metabolism.
- Trial name
- NCT02033005
- Where
- United Kingdom
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Imperial College London
PostPartum Depression
The Effect of Exercise on Preventing PostPartum Depression
The purpose of this study is to examine the feasibility and efficacy of an exercise intervention for the prevention of postpartum depression.
- Trial name
- NCT00961402
- Testing
- Wellness Control, Exercise Intervention
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Suicide Prevention
Brief Suicide Intervention for Youth in Juvenile Detention Settings
This is an intervention development study and therefore is not designed or powered to test hypotheses. Following initial development and refinement of intervention and protocol, an open trial will be conducted at one juvenile…
- Trial name
- NCT05225103
- Testing
- SAFETY-Acute intervention
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Duke University
Stress, Psychological, Loneliness
Ecological Momentary Assessment and Text Message Intervention for Stress Management
Feasibility and acceptability of an Ecological Momentary Assessment (EMA) compared with an EMA plus automated text message intervention for stress management
- Conditions
- Stress, Psychological, Loneliness, Covid19, Stress
- Trial name
- NCT04907942
- Testing
- EMA + EMA and FACE Stress, EMA Alone
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Click Therapeutics, Inc.
Smoking Cessation, Overweight
Internet-Administered Smoking Cessation Treatment for Overweight and Obese Smokers
This project will be a randomized clinical trial testing the efficacy of an internet-administered smoking cessation treatment for overweight and obese smokers.
- Conditions
- Smoking Cessation, Overweight, Obesity
- Trial name
- NCT01259466
- Testing
- Nicotine patch
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Yale University
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