Clinical trials: Behaviour
Smoking Cessation, Psychiatric Illness
Reducing Cardiovascular Disease by Combining Smoking Cessation Pharmacotherapy and Behavioural Counseling
Research Aims The aims of this research study are: 1. To determine which of the following three smoking cessation medications is most effective in achieving cessation: Nicotine Patch Nicotine Patch + gum or inhaler Varenicline…
- Trial name
- RW (NCT01623505)
- Testing
- Champix, Transdermal Nicoderm patch combined with gum or inhaler, Transdermal Nicoderm patch
- Where
- Canada
- Volunteers
- 738 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Cardiovascular Diseases, Sickle Cell Disease
SCD Fit Homebase Program
The purpose of this project is to develop novel approaches to promote health and longevity while enhancing quality of life among persons with Sickle cell disease (SCD).
- Conditions
- Cardiovascular Diseases, Sickle Cell Disease, Exercise
- Trial name
- NCT05228756
- Testing
- Accelerometer
- Sponsor
- University of Alabama at Birmingham
HIV/AIDS, Sexual Behavior
Reducing HIV Risk in Urban Women: Soap Opera Videos on Video-Capable Cell Phones
Background: Love, Sex, and Choices (LSC) is a soap opera video series created to reduce HIV sex risk in women. Methods: LSC was compared to text messages in a randomized trial in 238 high-risk mostly Black young urban women.
- Conditions
- HIV/AIDS, Sexual Behavior, Woman's Role, Risk Behavior
- Trial name
- NCT03330522
- Testing
- Love, Sex, & Choices video series, Messages in text
- Where
- United States
- Volunteers
- 295 people
- Sponsor
- Northeastern University
Asthma.
Effect of Aerobic Training in Moderate or Severe Asthmatic Patients
Exercise training has been proposed as adjunctive therapy in asthma to improve many clinical outcomes; however its effects on bronchial hyperresponsiveness (BHR) and inflammation, characteristic features in asthma, remains poorly…
- Trial name
- ETA1 (NCT02033122)
- Testing
- Aerobic training, Breathing exercise
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Instituto de Investigação em Imunologia
Health Care Utilization
Economic and Clinical Outcomes of (Whole Exome) Sequencing in Tapestry
The purpose of this research is to learn more about the impact of genetic testing on healthcare costs, clinical care, and quality of life.
- Trial name
- ECOST (NCT05045222)
- Where
- 2 sites in United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Chronic Low-back Pain, Patient Activation
Self-Management of Chronic Low Back Pain: Targeting Patient Activation
Patients with chronic low back (cLBP) pain report reduced physical function and ability to participate in social roles and are more likely to use opioid pain medications.
- Trial name
- NCT06236529
- Testing
- Health Behavior Change Counseling, Self-management program
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Johns Hopkins University
Attention Deficit-Hyperactivity Disorder
Real World Evidence of the Efficacy and Safety of FOQUEST
This study is a four-month, phase IV, open-label study of ADHD symptomatology and functional outcomes in pediatric (6 to 17 years old) and adult (≥18 years or older) patients with ADHD treated with FOQUEST or VYVANSE.
- Trial name
- reFOQus (NCT04152629)
- Testing
- Methylphenidate Hydrochloride, Lisdexamfetamine Dimesylate
- Where
- 12 sites in Canada
- Volunteers
- 257 people
- Sponsor
- Purdue Pharma, Canada
Nipple Trauma
Laser Therapy in Nipples Injured During Breastfeeding
This study aims to evaluate the effect of low-level laser in pain relief and tissue repair in mothers with nipple trauma during breastfeeding, compared to a control group.
- Trial name
- LTNIBF (NCT01723995)
- Testing
- low-level laser on nipples
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Federal University of São Paulo
Smoking ( Cigarette), Smoking (Tobacco) Addiction
Smoking Cessation With Wearables to Improve General, Oral Health and Quality of Life
Tobacco smoking remains one of the leading preventable causes of disease, disability, and premature death worldwide. According to the World Health Organization, tobacco use is responsible for more than eight million deaths each…
- Conditions
- Smoking ( Cigarette), Smoking (Tobacco) Addiction, Smoking Behaviors, Smoking Cessation
- Trial name
- Wear-Smile (NCT07593742)
- Testing
- Telemedicine-Based Smoking Cessation Program, Conventional Smoking Cessation Behavioral Program
- Volunteers
- 102 people
- Sponsor
- University of Salerno
Physical Activity
The Causal Impact of Online Social Media on Physical Activity: A Randomized Controlled Trial
The overall objective of this research is to collect data for understanding whether messages in online environments impact fitness attitudes and behaviors.
- Trial name
- NCT02267369
- Testing
- Media-assisted fitness program, Social network-assisted fitness program, Basic fitness program
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Renal Colic, Urolithiasis
Renal Colic and Urolithiasis in Poland
The aim of this study is to analyze the prevalence, effect on quality of life, and treatment-related behaviors for renal colic and urolithiasis in a population-representative sample of Poles.
- Trial name
- POLSTONE (NCT06176469)
- Testing
- No intervention
- Where
- Poland
- Volunteers
- 10,000 people
- Sponsor
- Mikolaj Przydacz
Obesity
Comparison of Body Composition Changes With Weight Loss Interventions
This study is being done to compare the effects of a newer class of weight loss medications to weight loss surgery on the body's muscle, metabolism, and side effects over time.
- Trial name
- REFORM (NCT07115069)
- Testing
- GLP-1 receptor agonist, Gastric Bypass Surgery (laparoscopic), Gastric Bypass Surgery (robotic)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vanderbilt University Medical Center
Work Related Stress
Validation of an Employee Remote Workplace Stress Measure Embedded Within a Novel Employee Wellbeing App
This study aims to validate an adapted workplace stress scale (American Institute of Stress) for employees working remotely during the COVID-19 pandemic.
- Trial name
- NCT04752683
- Testing
- MyBuddy Employee Wellbeing App
- Volunteers
- 220 people
- Sponsor
- Holly Risdon
Depression and Suicide Ideation, Anxiety
Culturally Adapted Psychological Support for Conflict-Affected Afghans: Study Protocol on Mental Health & Violence
This pilot study examines the feasibility and acceptability of a culturally adapted psychological intervention-Problem Management Plus with Emotional Processing (PM+ EP)-for young Afghans aged 16-30 experiencing high…
- Conditions
- Depression and Suicide Ideation, Anxiety, PTSD
- Trial name
- NCT06980441
- Testing
- Problem Management Plus with Emotional Processing module
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Peace of Mind Association (PoMA)
Chronic Pain, Chronic Pain Due to Injury
Virtual Pain Education for Spinal Cord Stimulation Patients
Chronic pain is a leading cause of disability in the United States. When standard treatments fail, many patients develop treatment resistant pain and undergo Spinal Cord Stimulation (SCS) therapy.
- Conditions
- Chronic Pain, Chronic Pain Due to Injury, Failed Back Syndrome, Persistent Spinal Pain Syndrome
- Trial name
- SCS-PNE (NCT07743905)
- Testing
- SCS-PNE intervention
- Volunteers
- 50 people
- Sponsor
- University of Arkansas
Patient Relations, Nurse, Patient Satisfaction
Aromatherapy Methods in Reducing Anxiety Before Breast Biopsy
A breast biopsy is a cause for anxiety for most women when faced with a diagnosis of breast cancer. Physiological and psychological effects of breast biopsy may continue in the pre-biopsy and post-biopsy period.
- Conditions
- Patient Relations, Nurse, Patient Satisfaction, Anxiety State, Breast Cancer
- Trial name
- NCT05276505
- Testing
- Lavender Aromatherapy Tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Suicide
Suicide Prevention for Sexual and Gender Minority Youth (Open Trial)
The overarching goal of this study is to develop a suicide prevention program for sexual-and-gender-minority youth and emerging adults.
- Trial name
- NCT05087966
- Testing
- Safety Planning Intervention with Navigation Services
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Electronic Cigarette Use, E-Cig Use
Effects of e-Cigarettes on Perceptions and Behavior - Substudy 2
This project will assess the ways in which e-cigarette product diversity impacts the user experience to inform potential regulations by identifying product characteristics that may: (1) put young adults at risk for tobacco…
- Conditions
- Electronic Cigarette Use, E-Cig Use, Cigarette Smoking, Cigarette Use, Electronic
- Trial name
- NCT05958966
- Testing
- E-cigarette e-liquid self-administration
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Agitation in Patients With Dementia of the Alzheimer's Type, Alzheimer Disease
Addressing Dementia Via Agitation-Centered Evaluation
This is a multi-center, randomized, double-blind, placebo-controlled study, to assess the efficacy and safety of AXS-05 in the treatment of agitation in patients with Alzheimer's disease.
- Conditions
- Agitation in Patients With Dementia of the Alzheimer's Type, Alzheimer Disease, Agitation,Psychomotor
- Trial name
- ADVANCE (NCT03226522)
- Testing
- AXS-05, Bupropion
- Where
- 78 sites in United States, Australia
- Volunteers
- 366 people
- Sponsor
- Axsome Therapeutics, Inc.
Dementia
Multidisciplinary Intervention for Challenging Behaviour (Agitation) in Patients With Dementia
The increasing prevalence of dementia is a major challenge to the health authorities in most countries. Nearly all the persons suffering from dementia experience behavioural and psychological symptoms (BPSD).
- Trial name
- TID (NCT01183351)
- Testing
- Psychosocial intervention
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Sykehuset Innlandet HF
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