Clinical trials: Benign Lymph Node Neoplasm
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Colorectal Neoplasms Malignant
Significance of Benign Lymph Node Enlargement in Colorectal Cancer
The objective of this observational study was to investigate the clinical significance of benign mesenteric lymph node （BLNE） enlargement in patients with colorectal cancer.
- Trial name
- NCT06410729
- Testing
- Observational study, no intervention
- Volunteers
- 2,270 people
- Sponsor
- Peking University Third Hospital
Lymphadenopathy, Lymphnode Metastasis
Value of Super-resolution Ultrasonography in Differentiating Benign and Malignant Lymph Nodes
Lymph nodes are one of the most important components of the human immune system, and superficial lymph node enlargement lacks specificity.
- Conditions
- Lymphadenopathy, Lymphnode Metastasis, Lymphoma, Lymphatic Tuberculosis
- Trial name
- NCT07155954
- Testing
- SRUS imaging of the lymph nodes before surgery or biopsy
- Where
- China
- Volunteers
- 779 people
- Sponsor
- Peking University Third Hospital
Pancreatic Cancer, Secondary Malignant Neoplasm of Lymph Node
Clinical Impact of EUS Elastography Mean Strain Histograms (SH) and Contrast Peak-enhancement in Focal Pancreatic Masses and Lymph Nodes
The study protocol is based on a multi-center semi-quantitative approach of EUS elastography data in combination with contrast-enhanced EUS, consisting of measuring SR and SH for focal pancreatic masses and lymph nodes, as well…
- Conditions
- Pancreatic Cancer, Secondary Malignant Neoplasm of Lymph Node, Benign Neoplasm of Lymph Nodes, Benign Pancreatic Tumors
- Trial name
- ADVEUS (NCT02459041)
- Testing
- Elastography, contrast enhancement
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- University of Medicine and Pharmacy Craiova
Gastric Cancer, Molecular Imaging
Novel Humanized Ferritin-Based NIR Fluorescent Probe for Identifying Sentinel Lymph Node Metastasis in Early Gastric Cancer
With the widespread adoption of early cancer screening, the proportion of early gastric cancer (EGC) in China has been gradually increasing. The primary treatments for EGC are endoscopic and surgical interventions.
- Trial name
- NCT07294638
- Testing
- VE/CX-FTn-ICG injection solution
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Thyroid Diseases, Thyroid Neoplasms
Thyroid Health Outcomes Registry for Surgery
THORS is a single-center ambidirectional observational cohort study conducted at Moscow Multidisciplinary Clinical Center "Kommunarka".
- Conditions
- Thyroid Diseases, Thyroid Neoplasms, Thyroid Cancer, Thyroid Nodules
- Trial name
- THORS (NCT07812779)
- Volunteers
- 3,000 people
- Sponsor
- Pirogov Russian National Research Medical University
Stomach Neoplasms, Benign
Identification of Therapeutic Targets in Metastatic Gastric Cancer
This is a pilot study aiming at identifying novel therapeutic molecular targets in patients with gastric cancer with lymph nodes or distant metastasis.
- Trial name
- NCT07551440
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, Benign and Malignant Mediastinal and Hilar Lymph Nodes Known or Suspected Malignancy
Procedural Outcomes in Endobronchial Ultrasound - Transbronchial Needle Aspiration (EBUS-TBNA) With and Without Rapid On-Site Evaluation (ROSE)
The objective of this study is comparing the attributable procedural time of Endobronchial Ultrasound - Transbronchial Needle Aspiration (EBUS-TBNA) when sampling mediastinal and hilar lymph nodes with or without Rapid On-Site…
- Trial name
- ROSE (NCT02028052)
- Testing
- ROSE, 22 gauge Vizishot needles
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Duke University
Malignancy or Benign of Enlarged Lymph Nodes
Endoscopic Ultrasound-guided Needle-based Confocal Laser Endomicroscopy for Evaluation of Malignant Lymph Nodes - a Pilot Study
Current modalities for lymph node staging in cancer can be limited. Needle-based confocal laser endomicroscopy (nCLE) is a novel endoscopic technique, which is compatible with the 19-gauge FNA needle.
- Trial name
- NCT02939066
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shandong University
Prostatic Neoplasms Benign, Radiotherapy Side Effect
Radiotherapy of Pelvic Lymph Nodes in High Risk Prostate Cancer - A Retrospective Analysis
Men with high risk prostate cancer who underwent radiotherapy of the prostate/seminal vesicles or underwent postoperative radiotherapy including pelvic lymph nodes between 2010 and 2016 are analyzed retrospectively.
- Conditions
- Prostatic Neoplasms Benign, Radiotherapy Side Effect, Lymph Node Disease
- Trial name
- NCT02998619
- Testing
- Radiotherapy
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- Kantonsspital Graubünden
Thyroid Cancer
The Evaluation of the Diagnostic Properties of Intra-operative In-situ Thyroglobin Levels of Cervical Lymph Nodes, in the Discrimination Between Benign and Malignant Lymph Nodes in Thyroid Cancer: a Prospective Multicentre Study.
Cytological examination of punctured lymph nodes is the gold standard for confirming metastatic lymph node spread of differentiated thyroid cancers.
- Trial name
- Tgcyto (NCT02602717)
- Testing
- lymph nodes cyto-punction
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Esophageal Squamous Cell Carcinoma, Benign Lymph Node Neoplasm
Quantitative Analysis of 18F-FAPI Dynamic PET/CT for Accurate Differential Diagnosis of MLN of ESCC
Patients diagnosed with esophageal squamous cell carcinoma based on clinicopathology, laboratory examination and imaging criteria were selected as the research subjects, and compared with conventional 18F-FDG PET/CT.
- Conditions
- Esophageal Squamous Cell Carcinoma, Benign Lymph Node Neoplasm, Malignant Lymph Node Neoplasm
- Trial name
- NCT05287880
- Testing
- Dynamic PET/CT
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Diagnosis, Axilla; Breast
Benign-Malign Differentiation of Axillary Lymph Nodes: The Role Of Superb Microvascular Imaging
102 patients who have suspicious ALNs were included in our prospective study, which was approved by a tertiary health care facility ethics committee.
- Trial name
- NCT05927727
- Testing
- Ultrasound and biyopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ankara Education and Research Hospital
Pancreatic Tumor, Benign, Solid Pseudopapillary Tumor of the Pancreas
Oncologic Safety and Lymphadenectomy in Parenchyma-Sparing Resection for SPN
Solid pseudopapillary neoplasm (SPN) of the pancreas is a low-grade malignant tumor primarily treated with surgical resection. However, the oncologic safety of parenchyma-sparing resection (PSR) and the necessity of…
- Trial name
- PSR for SPN (NCT07592663)
- Testing
- Parenchyma-sparing resection
- Where
- China
- Volunteers
- 708 people
- Sponsor
- Fudan University