Clinical trials: Benign Thyroid Nodule
Benign Thyroid Nodule
Drainless Thyroidectomy by the Sutureless Technique for Benign Thyroid Diseases
This randomized controlled trial evaluates the safety and feasibility of drainless thyroid surgery for benign thyroid diseases using a sutureless hemostatic technique.
- Trial name
- NCT07625865
- Testing
- sutureless thyroidectomy without drain, sutureless thyroidectomy with drain
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Minia University
Thermal Ablation, Fine Needle Aspiration Biopsy
Ultrasound and Cytological Evaluation 3 Years After Radiofrequency Thermal Ablation of Benign Thyroid Nodules : a Prospective Exploratory Cohort of 180 Nodules
There is no scientific data on post-thermal ablation cytological aspects, but treated nodules that grow back significantly after a procedure justify a new cytology in order not to ignore a neoplastic process.
- Conditions
- Thermal Ablation, Fine Needle Aspiration Biopsy, Thyroid Nodules
- Trial name
- CYTOTHYRAF (NCT05726981)
- Testing
- Fine needle aspiration biopsy (FNAB)
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thyroid Nodule
HIFU Reapplication in Benign Nodules
High Intensity Focused Ultrasound (HIFU) is a new approach in treating benign thyroid nodule without surgery. It is proven effective and safe relative to traditional surgery.
- Trial name
- NCT03331172
- Testing
- Echopulse
- Where
- Hong Kong
- Volunteers
- 28 people
- Sponsor
- The University of Hong Kong
Benign Thyroid Nodules
Study of the Feasibility of Radiofrequency Ablation of Benign Thyroid Nodules
The purpose of the present protocol is to evaluate the response rate to treatment of these symptomatic benign nodules with radiofrequency as an alternative to surgical treatment.
- Trial name
- TRAF (NCT03646383)
- Testing
- Radiofrequency ablation
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Toulouse
Thyroid Nodule, Thyroid Cancer
Cognition and QoL After Thyroid Surgery
The development of cognitive dysfunction can profoundly affect HR-QoL as well as the possibility of societal participation and ability to work, and thereby relevantly impacts prospects for cancer survivorship.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Cognitive Decline, Survivorship
- Trial name
- NCT05088187
- Where
- Sweden
- Volunteers
- 320 people
- Sponsor
- Karolinska University Hospital
Thyroid Diseases, Thyroid Neoplasms
Thyroid Health Outcomes Registry for Surgery
THORS is a single-center ambidirectional observational cohort study conducted at Moscow Multidisciplinary Clinical Center "Kommunarka".
- Conditions
- Thyroid Diseases, Thyroid Neoplasms, Thyroid Cancer, Thyroid Nodules
- Trial name
- THORS (NCT07812779)
- Volunteers
- 3,000 people
- Sponsor
- Pirogov Russian National Research Medical University
Thyroid Nodule
Ultrasound-guided Percutaneous Microwave Ablation for Benign Thyroid Nodules
Percutaneous microwave ablation(MWA) was reported as an effective modality for the management of thyroid nodules(TNs). This study aims to validate MWA as a feasible approach for patients with TNs for whom surgery is…
- Trial name
- NCT03057925
- Testing
- Microwave Ablation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenjun Wu
Thyroid Diseases
The Feasibility and Safety of the TOETVA for Benign Thyroid Nodules
Thyroid surgery has been developed as a new technique for zero scar in surgery by applying transoral endoscopic thyroidectomy with sublingual approach.
- Trial name
- NCT03158961
- Testing
- Transoral endoscopic thyroidectomy vestibular approach
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- The University of Hong Kong
Thyroid Nodule (Benign)
Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules
To evaluate long-term outcomes of ultrasound-guided thermal ablation for benign thyroid nodules
- Trial name
- NCT06729762
- Testing
- ultrasound-guided thermal ablation
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Chinese PLA General Hospital
Thyroid Nodule
Laser Ablation Versus Radiofrequency Ablation for Thyroid Nodules
The purpose of this study is to prospectively compare percutaneous radiofrequency ablation (RFA) versus percutaneous laser ablation (LA) for the treatment of solid thyroid nodules.
- Trial name
- LARA (NCT02714946)
- Testing
- Percutaneous Laser Ablation, Percutaneous Radiofrequency Ablation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Campus Bio-Medico University
Thyroid Nodule
Percutaneous Ethanol Injection for Benign Cystic Thyroid Nodules
Use of ethanol injection in treatment of cystic thyroid nodule
- Trial name
- NCT03257930
- Testing
- ethanol injection
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- hassan harby mohamed
Thyroid Nodule (Benign), Thyroid Nodule (Diagnosis)
Mortality Benefit of Ultrasound for Thyroid Nodules Identified With PET Imaging: Non-Inferiority Emulated Target Trial
The investigators hypothesize that all-cause mortality in patients with an incidental thyroid nodule on PET-CT who did not have thyroid ultrasound (the exposure) within 3 months of the PET-CT is non-inferior within a 5% margin to…
- Conditions
- Thyroid Nodule (Benign), Thyroid Nodule (Diagnosis), Thyroid Cancer
- Trial name
- NCT07255482
- Testing
- Thyroid Ultrasound
- Where
- United States
- Volunteers
- 874 people
- Sponsor
- Brigham and Women's Hospital
Thyroid Nodules, Thyroid Nodule
Comparing a New 3D Technology Used to Measure Thyroid Nodule Volume to Standard Ultrasound
After thyroid ablation procedure, the volume of the thyroid nodule (s) needs to be measured to see how well the procedure worked. Currently, these volumes are measured using traditional 2D ultrasound imaging.
- Trial name
- NCT07178080
- Testing
- PIUR tUS Infinity Ultrasound
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Sarasota Memorial Health Care System
Low Risk, Papillary Thyroid Cancer
Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers
To track the outcomes of patients who have been treated with RFA and its long-term effectiveness, and to learn more about the quality of life of patients who have received RFA in this study.
- Conditions
- Low Risk, Papillary Thyroid Cancer, Radiofrequency Ablation
- Trial name
- NCT07140757
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Thyroid Nodule, Insulin Resistance
Insulin Resistance and Metformin Use on Volume of Benign Thyroid Nodules
It has been shown that insulin might be involved in the pathogenesis of thyroid growth. Objective To evaluate the impact of IR and metformin use on the volume of benign thyroid nodules (TNs).
- Trial name
- NCT03183752
- Testing
- Metformin
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hospital Universitário Clementino Fraga Filho
Thyroid Nodule
Radiofrequency Ablation Study in LatinX Patients
Benign thyroid nodules can still create cosmetic, compressive, or hormonal issues for patients. In the past, surgery was typically used to treat thyroid nodules causing the above issues through partial or complete thyroidectomy.
- Trial name
- NCT05903196
- Testing
- Mygen V-1000 RF system
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Northwell Health
Thyroid Carcinoma, Thyroid Nodule (Benign)
Function Integrity of Neck Anatomy in Thyroid Surgery
Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy.
- Conditions
- Thyroid Carcinoma, Thyroid Nodule (Benign), Ablation; Retina
- Trial name
- NCT04666103
- Testing
- Intraoperative thermal ablation
- Where
- China
- Volunteers
- 1,264 people
- Sponsor
- Wuhan University
Benign Thyroid Nodules
Thermal Ablation Vs Thyroidectomy for Large Benign Thyroid Nodules
To compare the safety, efficacy and quality of life between staged thermal ablation and thyroidectomy in the treatment of Large benign thyroid nodules.
- Trial name
- NCT06607133
- Testing
- surgery, staged thermal ablation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Ming-an Yu
Thyroid Nodule
Effect of Ultrasound Guided Laser Ablation Therapy on Symptomatic Benign Thyroid Nodules
This is a prospective trial to evaluate the effects of laser ablation on symptomatic benign thyroid nodules. The study is designed to assess the clinical efficacy, safety, tolerability and impact on symptoms of single ultrasound…
- Trial name
- NCT04277455
- Testing
- Laser ablation of benign thyroid nodule
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johnson Thomas
Dysphagia, Esophageal, Dysphagia, Oral Phase
Post-thyroidectomy Dysphagia: An International Multicentric CONSORT - Compatible RCT
The most common and feared complications of total thyroidectomy are vocal cord paralyses and hypocalcemia. However, post-thyroidectomy dysphagia is not uncommon and has important consequences on the quality of life (QoL).
- Conditions
- Dysphagia, Esophageal, Dysphagia, Oral Phase, Dysphagia Comes and Goes, Thyroiditis
- Trial name
- Dysphagia-TT (NCT04410601)
- Testing
- Total thyroidectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Umraniye Education and Research Hospital