Clinical trials: Bicuspid
Edentulous Alveolar Ridge
Zero Echo Time MR for the Assessment of Maxillary Sinus and Dental Regions
The aim of this study is to evaluate the efficacy of zero echo time magnetic resonance imaging (ZTE MRI) as an ionizing radiation-free diagnostic method to evaluate both hard and soft tissues and maxillary sinus region before…
- Trial name
- ZTE-DENTAL (NCT06449443)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Orthodontic Appliance Complication
Evaluation of The Stability of Orthodontic Treatment After First Premolar Extraction Using Combined Retention Protocol
The aim of this study is to compare between the stability of anterior and posterior segments in both arches using bonded lingual retainers versus a combined protocol of retention (bonded lingual retainer and vacuum formed…
- Trial name
- NCT06502886
- Testing
- combined protocol of retention (bonded lingual retainer and vacuum formed retainers), Bonded lingual retainer
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp, Post Operative Pain
Effect of Vachellia Nilotica Versus Sodium Hypochlorite as Root Canal Irrigant on Postoperative Pain and Bacterial Load Reduction in Mandibular Premolar Teeth With Necrotic Pulp
The aim of this study is to assess the effect of V. nilotica extract solution versus 2.5% NaOCl on the intensity of postoperative pain and the amount of bacterial load reduction.
- Trial name
- NCT06116214
- Testing
- Vachellia Nelotica, sodium hypochlorite
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Anxiety, Pain
Effect of Aromatherapy on Pain and Anxiety During Orthodontic Extraction of Maxillary Premolars.
The goal of this randomized placebo-controlled split-mouth clinical trial is to determine whether aromatherapy using lemongrass essential oil can reduce pain, dental anxiety, and physiological stress responses during orthodontic…
- Trial name
- NCT07506135
- Testing
- Lemongrass Aromatherapy
- Where
- India
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pulpitis
The Use of Platelet-Rich Fibrin in Partial Pulpotomy Procedure
The aim of this study is to evaluate the clinical and histological pulp responses when MTA and a combined of MTA/PRF is used as pulp-capping agents after partial pulpotomy.
- Trial name
- NCT04331964
- Testing
- partial pulpotomy
- Where
- Syria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Damascus University
Pulpitis - Irreversible
Post Operative Pain of Root Canal Preparation With Wave One and Neolix in Acute Irreversible Pulpitis
the aim in this prospective in vivo randomized clinical trial to evaluate the influence of instrumentation technique ( reciprocation single file (wave one ) versus rotation single file (neolix) ) on post operative pain …
- Trial name
- NCT02952300
- Testing
- neolix, wave one
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Clinical Performance
Clinical Performance of Nano Fiber Reinforced Versus Conventional Nano Hybrid Composite in Restoring Premolars
In patients that need composite restorations in a compound proximal carious lesions in premolars, will the clinical performance of nano fiber reinforced resin composite restorations have similar results compared to those restored…
- Trial name
- NCT05808075
- Testing
- NovaProTM Fill Universal Dental Composite
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bicuspid Aortic Valve
Whole Exome Sequencing in Bicuspid Aortic Valve Patients
Bicuspid aortic valve (BAV), congenital anomaly present in 2% of the population, is defined by the presence of two sigmoid valves instead of three.
- Trial name
- NCT02899624
- Testing
- Extra blood draw samples, additional tissue samples
- Where
- France
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Orthodontic Treatment Via Premolar Extraction
Effect of Extraction Versus Non-extraction Orthodontic Treatment on the Third Molars
What is the effect of extraction orthodontic treatment in comparison to non- extraction treatment on the position, inclination and incidence of impaction of the third molars?
- Trial name
- NCT04857658
- Testing
- extraction orthodontic treatment plan
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Immediate Dental Implant
the Effect of Topical Application of Hyaluronic Acid on Immediate Dental Implant
The high predictability of immediate dental implants has led to routine use with a great expectation for success. Immediate implant placement in fresh extraction sockets was reported to reduce alveolar bone resorption, Better…
- Trial name
- NCT03691467
- Testing
- immediate dental implant, Hyaluronic Acid
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ibrahim Samy Kalboush
Orthodontic Extraction, Orthodontic Treatment
A Comparative Assessment of Post Extraction Pain in Orthodontic Patients to Evaluate the Effects of Early Engagement of Tooth with Orthodontic Wires. a Single Center Randomized Clinical Trial (RCT)
The goal of this clinical trial is to determine if the timing of tooth extractions (before or after initial orthodontic treatment) affects pain levels in patients who need bilateral extractions of first premolars in the upper…
- Conditions
- Orthodontic Extraction, Orthodontic Treatment, Orthodontic Treatment Via Premolar Extraction
- Trial name
- NCT06582836
- Testing
- The objective of the study was to investigate the effect of prior engagement of tooth with orthodontic appliance on post extraction pain among orthodontic patients
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Obstructive Sleep Apnea, Malocclusion
Premolar Extractions for Obstructive Sleep Apnea in Children With Overjet
This research aims to provide pediatric patients with polysomnography (a sleep study) before and after orthodontic treatment to determine if the extraction of upper premolars for treating excessive overjet results in an increase…
- Trial name
- NCT04946201
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mohamed Bazina
Gingival Recession, Lack of Keratinized Gingiva (Disorder)
Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites
The primary purpose of this protocol is to isolate, investigate and compare the regenerative and differentiation potential of mesenchymal stem cells (MSC's) in the gingival (gum) tissue harvested from two different locations from…
- Trial name
- NCT03570333
- Testing
- progenitor potential of Gingival Mesenchymal cells
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Aortic Aneurysm, Aortic Dissection
Cardiovascular Health Improvement Project
The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.
- Conditions
- Aortic Aneurysm, Aortic Dissection, Bicuspid Aortic Valve (BAV), Heart Failure
- Trial name
- CHIP (NCT02306200)
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Bone Augmentation, Badly Broken Maxillary Premolars Indicated for Extraction
Comparison of Immediate Implant Placement With Titanium Mesh Versus Collagen Membrane in Type II Socket:
Statement of the problem: Immediate implant placement is faced with several problems. One of the most important issues is dealing with defects in the buccal plate of bone in the esthetic zone.
- Trial name
- NCT06875830
- Testing
- collagen membrane, titanium mesh
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Misr International University
Tooth Loss, Partial Edentulism in the Maxilla or in the Mandible
Evaluation of Autogenous Bone Graft on Immediate Dental Implant Osseointegration Using Piezosurgery
This clinical study aims to evaluate the clinical and radiographic outcomes of immediate dental implant placement in mandibular premolar sites.
- Trial name
- ABG-IDIP (NCT07705399)
- Testing
- Immediate implant with autogenous bone graft, Immediate implant without bone graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Extra Canals
AI Detection Model of Extra Root Canals in Mandibular Premolars Using CBCT Scans
Successful endodontic treatment depends on the complete identification and management of the entire root canal system. Missed root canals are a major cause of endodontic failure, particularly in mandibular premolars, which…
- Trial name
- NCT07689708
- Testing
- AI Model to detect any extra canals in mandibular premolars
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp
Effect of Moringa Oleifera Leaf Extract on Postoperative Pain and Bacterial Reduction in Mandibular Premolars
The aim of this study is to clinically compare the intensity of post-operative pain and the amount of bacterial reduction after using Moringa oleifera leaf extract solution during chemo-mechanical preparation, versus 2.5% NaOCl…
- Trial name
- NCT05348824
- Testing
- Moringa oleifera leaf, Sodium hypochlorite
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth, Nonvital
Pain Following One-visit Versus Two-visit Root Canal of Necrotic Teeth Using Protaper Next
To evaluate the incidence and severity of postoperative pain after root canal therapy of necrotic teeth in one appointment versus two appointments using Protaper next instrument.
- Trial name
- NCT02984488
- Testing
- single visits, two visits
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Immediate Dental Implant
The Effect Of Hyaluronic Acid And Melatonin With Systemic Administration of Vitamin C On Implant Stability After Immediate Implant in Anterior Region
The concept of immediate implant placement at the time of tooth extraction was first introduced by Schulte et al. on animal studies.
- Trial name
- NCT03804177
- Testing
- immediate implant placement with melatonin hyaluronic acid vit C, immediate implant placement without melatonin hyaluronic acid vit C
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University