Clinical trials: Bifidobacterium
Healthy
Impact of Native Chicory Inulin on Change and Persistence of Gut Microbiota
The main aim of this study is to investigate differences in rate, extent of change and persistence of the gut microbiota in healthy adult volunteers in response to native chicory inulin.
- Trial name
- INFLUX (NCT06528041)
- Testing
- Inulin, Maltodextrin
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Purdue University
Oral Mucositis, Quality of Life
Effect of Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules on Oral Mucositis in Nasopharyngeal Carcinoma Patients Receiving Radiotherapy.
Effect of Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules on Oral Mucositis in Nasopharyngeal Carcinoma Patients Receiving Radiotherapy.
- Trial name
- NCT03112837
- Testing
- Lactobacillus, Bifidobacterium and Enterococcus
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jiangxi Provincial Cancer Hospital
Colic, Infantile, Probiotic
NEOBIFI: Clinical Trial for the Prevention and/or Reduction of the Incidence of Colics in Infants
Infant colics represent a clinical condition in childhood, characterized by an uncontrollable crying that occurs without any apparent organic cause.1 They can be associated with face redness, closed fists, thighs flexion…
- Conditions
- Colic, Infantile, Probiotic, Gut Microbiome, Bifidobacterium Breve
- Trial name
- NEOBIFI (NCT03219931)
- Testing
- Bifidobacterium breve BR03 and Bifidobacterium breve B632
- Where
- Italy
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Infant Development, Safety Issues
Safety of Bifidobacterium Breve PS1 for Infants
The objective of this work was the characterization of the probiotic potential of Bifidobacterium breve PS1, a strain originally isolated from human milk.
- Trial name
- NCT05973812
- Testing
- Infant formula supplemented with Bifidobacterium breve PS1, Infant formula NOT supplemented with Bifidobacterium breve PS1
- Where
- 3 sites in Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Dental Caries, Oral Health
Effect of Probiotics Containing Yogurts on the Composition of Biofilms in Patients Under Orthodontic Treatment
Aim: To assess in vivo if the intake of yogurt containing Bifidobacterium animalis ssp. lactis DN- 1173010 probiotic for a period of 2 weeks affects the salivary levels or biofilms of mutans streptococci and the lactobacilli of…
- Trial name
- NCT01657539
- Testing
- Yogurt containing probiotics
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Healthy Volunteers
Effects of Bifidobacterium Longum BB536 on Incidence of Acute Diarrhea and/or Respiratory- Related Illnesses in Children
This project aims to study the benefits of probiotics namely Bifidobacterium longum BB536 in prevention of acute diarrhea and/or respiratory-related illnesses, which are found common among children in Malaysia aged from 2 to 6…
- Trial name
- NCT02434042
- Testing
- BB536
- Where
- Malaysia
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Healthy Adult Volunteer
The Effect of Bifidobacterium Probiotics on Gut Microbiota Changes in Healthy Adults During Short-term Travel Along the Silk Road
Journeying along the historic Silk Road exposes travelers to dramatic dietary shifts, unfamiliar microbial environments, and the physical stresses of long-distance travel-all known to disrupt gut health and cause gastrointestinal…
- Trial name
- NCT07182500
- Testing
- Probiotic
- Where
- 2 sites in China, Malaysia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Food Allergy in Infants
The Role of Bifidobacterium Intervention in Food Allergic Infants
Infant food protein allergy is the most common allergic disease in children, which can lead to infantile-specific dermatitis, intestinal inflammation, and so on.
- Trial name
- NCT05965063
- Testing
- Bifidobacterium M-16V, allergy food avoidance
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Fecal Microflora in the Formula Fed Premature Infant
The Impact of Oligosaccharides and Bifidobacteria on the Intestinal Microflora of Premature Infants
The purpose of this study is to see whether dietary supplements can change the germs in the intestines of premature infants to be more like those of healthy breast fed term babies.
- Trial name
- NCT00810160
- Testing
- ProlactPlus, GOS galacto-oligosaccharides, Bifidobacterium infantis
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Mucositis Oral
Effect of Probiotic Use Bifidobacterium Animalis Subsp. Lactis in Peri-implant Mucositis
Peri-implant disease is an inflammatory process of bacterial etiology that can affect the tissues around the implants and can be classified as peri-implant mucositis or peri-implantitis.
- Trial name
- Mucosite prob (NCT04187222)
- Testing
- Mechanical debridements, Bifidobacterium animalis subsp. lactis
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Constipation
Effect of the Consumption of a Cheese Enriched With Probiotic Organisms in Improving Symptoms of Constipation
Constipation is a common gastrointestinal motility disorder, chronic condition that often negatively affects the daily lives of patients due to their symptoms, such as infrequent stools, hard stools, straining or painful…
- Trial name
- NCT01680432
- Testing
- Probiotic fresh cheese, Regular Cheese
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centro Universitário Univates
Signs and Symptoms, Digestive, Dyspepsia
Evaluation of the Effect of a Probiotic Supplement Upon Gastrointestinal Function
The purpose of this pilot study is to evaluate whether a probiotic supplement improves gastrointestinal (GI) function.
- Trial name
- NCT02928484
- Testing
- Probiotic mix CBP-004019/C
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Biopolis S.L.
Healthy
Influence of Food Matrix on Prebiotic Efficacy in Inulin Type Fructans
The aim of the study is to investigate whether the food matrix has an influence on the prebiotic efficacy (bifidobacteria growth) of chicory-derived Orafti® inulin in healthy adult volunteers.
- Trial name
- NCT05581615
- Testing
- Inulin
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beneo-Institute
Caries, Dental
Effect of Lactobacillus Rhamnosus GG and Bifidobacterium Longum in Children Aged 3 to 5 Years of Villavicencio and Pasto
The objective of this pilot study is to determine if the presence of bacteria with probiotic characteristics (Lactobacillus rhamnosus GG and Bifidobacterium longum) in a commercial milk, control some measures that indicate…
- Trial name
- NCT03078179
- Testing
- Commercial Dairy Cow Milk, Commercial Cow Milk with Probiotic
- Where
- 3 sites in Colombia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cooperative University of Colombia
A03 - Digestive System, B03 - Bacteria
Fermented Dairy Product and Bifidobacterium Diversity (ThreeBees)
Bifidobacterium strains with potential health benefits can contribute to the gastrointestinal wellbeing. However, the ability of these strains to survive gastro-intestinal tract stress and their impact on gut microbiome remains…
- Trial name
- ThreeB (TB) (NCT06799364)
- Testing
- 28-days consumption of Product A in 45 to 60-year-old healthy subjects., 28-days consumption of Product B in 45 to 60-year-old healthy subjects., 28-days consumption of Control product in 45 to 60-year-old healthy subjects.
- Where
- 3 sites in France
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Reduction of Small Intestinal Ulceration Risk
The Effect of a Probiotic Strain on Ibuprofen-induced GI Damage
To investigate if a daily dose of minimum 15 billion CFU of Bif195 reduces the risk of small-intestinal tissue damage in an Ibuprofen challenge model as assessed by video capsule endoscopy in a healthy US population.
- Trial name
- PIP-I (NCT04447924)
- Testing
- Bif195
- Where
- United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Atopic Dermatitis
The Effect of a Probiotic Intervention in Healthy Subjects and Patients With Atopic Dermatitis
The study was performed to investigate the effects of a probiotic supplementation containing Lactobacillus paracasei Lpc-37, Lactobacillus acidophilus 74-2 and Bifidobacterium animalis subsp. lactis DGCC 420 (B.
- Trial name
- NCT00550472
- Testing
- probiotics
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Jena
Gastrointestinal Symptoms
Effect of Bifidobacterium Lactis HN019 on Colonic Transit Time and Digestive Symptoms
The purpose of this study was to investigate the dose response effect of Bifidobacterium lactis HN019 supplementation on colonic transit time and gastrointestinal symptoms.
- Trial name
- NCT01171014
- Testing
- Bifidobacterium lactis HN019
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fonterra Research Centre
Subjective Sleep Quality, Objective Sleep Quality
Effect of B. Longum 1714™ on Sleep Quality
The aim of this study is to evaluate the effect of supplementation with the B. longum 1714™ strain on subjective and objective sleep quality in healthy participants.
- Trial name
- NCT04167475
- Testing
- Probiotic capsule
- Where
- Ireland
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- PrecisionBiotics Group Ltd.
Healthy Aging, Anti Aging
iVS-1 Probiotic Intervention Targeting Biological Aging in Midlife Adults
This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effects of Bifidobacterium adolescentis (iVS-1) supplementation on biological aging markers, metabolic health, and functional…
- Trial name
- VITAL (NCT07407894)
- Testing
- Bifidobacterium adolescentis iVS-1
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Synbiotic Health