Clinical trials: Bifidobacterium
Food Allergy in Infants
The Role of Bifidobacterium Intervention in Food Allergic Infants
Infant food protein allergy is the most common allergic disease in children, which can lead to infantile-specific dermatitis, intestinal inflammation, and so on.
- Trial name
- NCT05965063
- Testing
- Bifidobacterium M-16V, allergy food avoidance
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Abdominal Discomfort, Bloating
Study to Evaluate a Probiotic in Healthy Subjects With a History of Abdominal Discomfort and Bloating
This is a multicenter, double-blind, randomized, placebo-controlled, 6-week study of a probiotic for abdominal discomfort and bloating in healthy subjects.
- Trial name
- NCT01099696
- Testing
- B. infantis 35624
- Where
- 10 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Healthy
Probiotics and Health-related Quality of Life in Individuals With Seasonal Allergies
In this randomized, double-blind, placebo-controlled study, participants with seasonal allergies will receive a daily probiotic or placebo for 8 weeks.
- Trial name
- JEN (NCT02349711)
- Testing
- Probiotic mixture
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Florida
Adults, GLP-1
Impact of Probiotic (UltraFlora® Triplebiotic) on Weight Evolution on People After Discontinuation of GLP-1 Treatment.
This is a randomized, double-blind, double arm study involving 128 participants who will undergo a total participation period of 12 weeks.
- Trial name
- NCT07209046
- Testing
- UltraFlora® Triplebiotic
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Infant, Newborn, Immunity
The Bloom Infant Probiotic (BIP) Study
The goal of this clinical trial is to investigate whether administering a probiotic (Infloran®) to infants who received antibiotics in the first 28 days of life can restore or enhance their immune response to routine vaccines.
- Conditions
- Infant, Newborn, Immunity, Immunisation, Antibiotic Treatment
- Trial name
- BIP (NCT07189390)
- Testing
- Probiotic
- Where
- 2 sites in Australia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- South Australian Health and Medical Research Institute
Healthy
Probiotics (L. Gasseri, B. Bifidum, B. Longum) on Immune and Intestinal Health in Healthy Older Adults
The purpose of this study is to determine whether healthy older adults, aged 65 to 80 years, consuming a probiotic each day for three weeks will have improved immune strength and digestive health.
- Trial name
- NCT01662206
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Florida
Constipation, Intestinal Functional Disorder
The Efficacy Evaluation of TCI604 Probiotic on Intestinal Function Improvement
The objective of this study is to evaluate whether the TCI604 probiotics has the potential to enhance human gut function and alleviate constipation.
- Trial name
- NCT07135362
- Testing
- TCI604 probiotics
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Healthy Volunteers
Study Evaluating the Safety and Tolerability
The rationale for the current study is to initially evaluate the safety and tolerability of B. longum strain in healthy volunteers.
- Trial name
- NCT04692506
- Testing
- Probiotic
- Where
- Sweden
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Overweight , Obesity
Study on the Efficacy of Probiotics in the Treatment of Childhood Obesity and Their Effects on Gut Microbiota
This interventional study aims to evaluate the efficacy of a probiotics supplementation (Bifidobacterium longum subsp. longum Dipro-O and Bifidobacterium longum subsp.
- Trial name
- NCT07448220
- Testing
- Probiotic
- Where
- 2 sites in China, Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Min-Tze LIONG
A03 - Digestive System, B03 - Bacteria
Fermented Dairy Product and Bifidobacterium Diversity
Bifidobacterium strains with potential health benefits can contribute to the gastrointestinal wellbeing. However, the ability of these strains to survive gastro-intestinal tract stress and their impact on gut microbiome remains…
- Trial name
- NCT07700381
- Testing
- 28-days consumption of Product A in 45 to 60-year-old healthy subjects, 28-days consumption of Control product in 45 to 60-year-old healthy subjects
- Where
- France
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Defecation Irregularity
Effects of Fermented Dairy Products on Defecation Changes Through Gut Microbiota
The investigators recruited participants aged 20-65 years who did not have gastrointestinal diseases and who were not taking medication for digestive symptoms (e.g., gastric acid inhibitors, antibiotics, sterilization…
- Trial name
- NCT06862310
- Testing
- yogurt intervention
- Where
- Taiwan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Changes in Gut Microbiota, Gut Metabolites, Respiratory Symptoms, and Well-being Index
A Probiotic for Health Outcomes in Short-Term Overseas Travel
With the improvement of living standards, travel has become a common form of leisure. However, travelers often face changes in living environments, dietary habits, and sleep schedules, all of which can impact the gut microbiota…
- Trial name
- NCT07705659
- Testing
- Bifidobacterium longum, Maltodextrin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- DiproBio (Shanghai) Co., Ltd.
Healthy
Impact of Native Chicory Inulin on Change and Persistence of Gut Microbiota
The main aim of this study is to investigate differences in rate, extent of change and persistence of the gut microbiota in healthy adult volunteers in response to native chicory inulin.
- Trial name
- INFLUX (NCT06528041)
- Testing
- Inulin, Maltodextrin
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Purdue University
Healthy Volunteers
Effects of Bifidobacterium Longum BB536 on Incidence of Acute Diarrhea and/or Respiratory- Related Illnesses in Children
This project aims to study the benefits of probiotics namely Bifidobacterium longum BB536 in prevention of acute diarrhea and/or respiratory-related illnesses, which are found common among children in Malaysia aged from 2 to 6…
- Trial name
- NCT02434042
- Testing
- BB536
- Where
- Malaysia
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Male Infertility
Effect of Antioxidant Probiotic Administration on Seminal Quality and Reproductive Outcomes.
The quality of semen plays a fundamental role in correct fertilization and development of normal embryos that result in a live birth. Unfortunately, semen quality has declined during the last decades, and reduced more and more.
- Trial name
- NCT04585984
- Testing
- Experimental - Probiotic
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Fundación IVI
Healthy, Healthy Nutrition
The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial
The goal of The BEGIN Study, a randomized controlled double-blinded intervention trial, is to learn if probiotics, with Bifidobacterium longum subspecies infantis Bifin02 (B.
- Trial name
- BEGIN (NCT06452199)
- Testing
- B. infantis
- Where
- 2 sites in Denmark
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pain
Efficacy of Yogurt Containing BB12 in Subjects With GI Symptoms
The purpose of this study is to determine if probiotics bacteria, specifically bifidobacterium lactis (BB12) improve gastrointestinal symptoms in subjects with functional gastrointestinal symptoms (i.e., non-patients…
- Trial name
- NCT00618488
- Testing
- Probiotic BB12 - Bifidobacterium lactis
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of North Carolina
Bacterium; Agent
Colonization and Persistence of Bifidobacterium Longum
Healthy adults referred to as the absence of intestinal disorders, liver and kidney problems, lactose intolerance, and no use of ongoing medication for chronic diseases will be recruited.
- Trial name
- NCT01650753
- Testing
- Probiotic Powder
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Lower Abdominal Pain, Diarrhea
Efficacy and Safety of Encapsulated Bifidobacterium Longum BBH016 in Subjects With Lower Gastrointestinal Symptoms
Functional lower gastrointestinal (GI) symptoms such as abdominal pain, diarrhea, loose stools, and bloating are common in adults without identifiable organic disease and are associated with impaired quality of life and increased…
- Conditions
- Lower Abdominal Pain, Diarrhea, Irritable Bowel Syndrome
- Trial name
- NCT07484412
- Testing
- Bifidobacterium longum BBH016
- Where
- South Korea
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Healthy Adults (45-65 Years)
Effect of Bifidobacterium Adolescentis on Aging in Healthy Adults (45-65 Years)
This study will include middle-aged and elderly people aged 45-65 years to carry out the translational study of Bifidobacterium adolescentis, and design a double-blind, randomized controlled clinical trial according to strict…
- Trial name
- NCT05603455
- Testing
- Bifidobacterium adolescentis
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine