Clinical trials: Bilateral Vestibulopathy
Reflex, Abnormal, Bilateral Vestibulopathy
Covert Saccade Triggers in Bilateral Vestibular Hypofunction
Patients with chronic bilateral vestibular hypofunction may suffer from a visual instability during head movement called oscillopsia.
- Conditions
- Reflex, Abnormal, Bilateral Vestibulopathy, Healthy Volunteers
- Trial name
- CS-TRIGGER (NCT04268615)
- Testing
- Covert Saccades and Virtual Reality, Actives versus passives Head Impulses, Visually guided saccades
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Vestibulocochlear Nerve Diseases, Vestibular Disorder
Vestibular Balance Therapy Intervention for Children
The goal of this within groups clinical trial is to determine the feasibility of a home-based vestibular balance therapy program for children with vestibular hypofunction.
- Conditions
- Vestibulocochlear Nerve Diseases, Vestibular Disorder, Bilateral Vestibular Loss
- Trial name
- VBT-C (NCT05741515)
- Testing
- Vestibular Balance Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Alabama at Birmingham
Bilateral Vestibular Loss
VertiGO! - Get up and GO! With the Vestibular Implant
In the VertiGO! trial 13 participants with bilateral vestibulopathy (BV) and severe sensory neural hearing loss in the ear to be implanted will receive a combined cochlear (CI) and vestibular implant (VI), capable of stimulating…
- Trial name
- NCT04918745
- Testing
- Cochlear Vestibular Implant (CVI) - in-hosptial, Cochlear Vestibular Implant (CVI) - home-use (preference)
- Where
- Netherlands
- Volunteers
- 13 people
- Sponsor
- Maastricht University Medical Center
Vestibular Diseases
Covert-saccades, Dynamic Visual Acuity and Quality of Life
Patients with chronic bilateral vestibular hypofunction may suffer from a visual instability during head movement called oscillopsia.
- Trial name
- COSQOL (NCT02753179)
- Testing
- Head Impulse Tests, Dynamic visual acuity Test (DVAT), VEMPs & VEMPo
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Cerebellar Ataxia, Neuropathy
Evaluation of Urinary Dysfunction in CANVAS Patients
The investigator wishes to evaluate the prevalence of urinary symptoms in patients diagnosed with Cerebellar Ataxia, Neuropathy, Vestibular Areflexia Syndrome (CANVAS).
- Conditions
- Cerebellar Ataxia, Neuropathy, Vestibular Areflexia
- Trial name
- UROCANVAS (NCT06817707)
- Testing
- Evaluation of urinary dysfunction in patients with CANVAS
- Where
- 3 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cough, Cerebellar Ataxia
Chronic Cough and CANVAS (Cerebellar Ataxia With Neuropathy and Bilateral Vestibular Areflexia Syndrome)
Chronic cough is a frequent cause of Pneumology consultations. CANVAS syndrome (Cerebellar Ataxia with Neuropathy and bilateral Vestibular Areflexia Syndrome) is a progressive and disabling neurological disease that very…
- Conditions
- Cough, Cerebellar Ataxia, Gastroesophageal Reflux
- Trial name
- CANVAS (NCT04703595)
- Testing
- To determine the presence of biallelic expansion of AAGGG in RFC1 in patients with chronic cough, regardless of the presence of neurological symptoms.
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Hearing Loss, Sensorineural, Bilateral Vestibular Deficiency
Inventory of Radiological and Vestibular Function in Cochlear Implant Candidates
In 2014 radiological lesions at one or more semicircular canals (SCC) were described using CT \& MR imaging in subjects presenting advanced hearing and vestibular deterioration caused by the p.P51S mutation in COCH.
- Conditions
- Hearing Loss, Sensorineural, Bilateral Vestibular Deficiency, DFNA9, Radiology
- Trial name
- NCT04066270
- Testing
- video nystagmography
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Jessa Hospital
Vestibular Dysfunction, Bilateral Vestibular Loss
Spatial Orientation, Navigation, and Neuropsychologic Function in Patients With Vestibular Implant
The vestibular system, located in the inner ear, provides information to the brain information about how head acceleration and orientation relative to gravity.
- Conditions
- Vestibular Dysfunction, Bilateral Vestibular Loss, Vestibular Implant
- Trial name
- NCT07627087
- Testing
- vestibular implant stimulation
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Vestibular Disorder, Vestibular Ataxia
Vestibular Implants Tested in Human Subjects
The goal of this study is to improve the vestibular implant's ability to reduce the vestibular-dependent perceptual, postural, and visual symptoms that affect patients with severe peripheral vestibular damage.
- Conditions
- Vestibular Disorder, Vestibular Ataxia, Vestibular Loss, Bilateral
- Trial name
- NCT04905472
- Testing
- Vestibular prosthesis/implant, Vestibular Implant Stimulation
- Where
- 3 sites in United States, Switzerland
- Sponsor
- Massachusetts Eye and Ear Infirmary
Cerebellar Ataxia
Evaluation of the Diagnostic Value of Video-oculography in CANVAS Neuronopathies
Cerebellar ataxia syndrome with neuropathy and vestibular areflexia (CANVAS) is a genetic pathology of recent discovery (bi-allelic expansion in intron 1 of the RFC1 gene with AAGG repetition).
- Trial name
- VOG-Neuropat (NCT05278091)
- Testing
- None, pure observationnal study
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Vertigo, Functional Dizziness
Impact of Vertigoheel® on Patients Suffering From Bilateral Vestibulopathy and Functional Dizziness
In this study the researcher observe how vertigo symptoms change during two months of treatment with the natural medicinal product Vertigoheel©.
- Conditions
- Vertigo, Functional Dizziness, Bilateral Vestibulopathy
- Trial name
- HealVertigo (NCT05897853)
- Where
- Germany
- Volunteers
- 62 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Idiopathic Bilateral Vestibulopathy
Idiopathic Bilateral Vestibulopathy: Peripheral Vestibular Disorders and Their Repercussions
The goal of this exploratory study is to gain a better understanding of the symptomatology of idiopathic bilateral vestibulopathy (IBV) by characterising as precisely as possible the type and intensity of each patient's…
- Trial name
- VBI (NCT06476587)
- Testing
- Assessment of postural stability and active motion perception, Cognitive tests, Eccentric axis rotation
- Where
- France
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Bilateral Vestibular Hypofunction, Bilateral Vestibulopathy
MRI Performance and Risk Factors in Bilateral Vestibular Hypofunction
Bilateral vestibular hypofunction (BVH) is a chronic disorder in which the balance organs or vestibular pathways on both sides do not work normally.
- Conditions
- Bilateral Vestibular Hypofunction, Bilateral Vestibulopathy, Presbyvestibulopathy
- Trial name
- MPARFIBVH (NCT07709143)
- Testing
- Multimodal Neuroimaging and Vestibular Function Assessment
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai 6th People's Hospital
Hearing Loss, Sensorineural, Bilateral Vestibulopathy
Effect of Hearing Loss and Vestibular Decline on Cognitive Function in Older Subjects
The world population has been growing and aging dramatically, with a rising prevalence of dementia. Worldwide, around 50 million people have dementia, with 10 million new cases added every year.
- Conditions
- Hearing Loss, Sensorineural, Bilateral Vestibulopathy, Alzheimer Disease, Mild Cognitive Impairment
- Trial name
- GECkO (NCT04385225)
- Testing
- Longitudinal follow-up
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Other Disorders of Vestibular Function, Bilateral, Bilateral Vestibular Deficiency (BVD)
Vestibular Implantation to Treat Adult-Onset Bilateral Vestibular Hypofunction
Although cochlear implants can restore hearing to individuals who have lost cochlear hair cell function, there is no widely available, adequately effective treatment for individuals suffering chronic imbalance, postural…
- Conditions
- Other Disorders of Vestibular Function, Bilateral, Bilateral Vestibular Deficiency (BVD), Gentamicin Ototoxicity, Labyrinth Diseases
- Trial name
- NCT05674786
- Testing
- Labyrinth Devices MVI™ Multichannel Vestibular Implant System
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Johns Hopkins University
Other Disorders of Vestibular Function, Bilateral, Bilateral Vestibular Deficiency (BVD)
Vestibular Implantation in Older Adults
Although cochlear implants can restore hearing to individuals who have lost cochlear hair cell function, there is no widely available, adequately effective treatment for individuals suffering chronic imbalance, postural…
- Conditions
- Other Disorders of Vestibular Function, Bilateral, Bilateral Vestibular Deficiency (BVD), Gentamicin Ototoxicity, Labyrinth Diseases
- Trial name
- NCT05676944
- Testing
- Labyrinth Devices MVI™ Multichannel Vestibular Implant System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University
Other Disorders of Vestibular Function, Bilateral, Bilateral Vestibular Deficiency (BVD)
Multichannel Vestibular Implant Early Feasibility Study
Although cochlear implants can restore hearing to individuals who have lost cochlear hair cell function, there is no adequately effective treatment for individuals suffering chronic imbalance, postural instability and unsteady…
- Conditions
- Other Disorders of Vestibular Function, Bilateral, Bilateral Vestibular Deficiency (BVD), Gentamicin Ototoxicity, Labyrinth Diseases
- Trial name
- NCT02725463
- Testing
- Labyrinth Devices MVI™ Multichannel Vestibular Implant
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Johns Hopkins University
Vestibular Disorder, Bilateral Vestibulopathy
Electrical Stimulation of the Peripheral Vestibular System in Order to Develop a Vestibular Implant
This study has three main goals (1) to explore the effects of electrical stimulations of the peripheral vestibular system(2) to assess the potential of this technique to rehabilitate basic vestibular functions in patients with…
- Conditions
- Vestibular Disorder, Bilateral Vestibulopathy, Bilateral Vestibular Loss
- Trial name
- NCT05246553
- Testing
- Electrical stimulation of the vestibular system, Electrical stimulation of the auditory system, Bilateral vestibulopathy Patients (BV)
- Where
- Switzerland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Nils Guinand
Neuropathy, Cerebellar Ataxia
Evaluation of the Peripheral Nerve Ultrasound as a Diagnostic Tool in CANVAS Neuropathies
Cerebellar ataxia with neuropathy and bilateral areflexia syndrome (CANVAS) is a late onset neurodegenerative disorder with a slowly progressive ataxia.
- Conditions
- Neuropathy, Cerebellar Ataxia, Neurodegenerative Diseases
- Trial name
- CANVAS (NCT05095870)
- Testing
- No intervention
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Bilateral Vestibular Hypofunction, Bilateral Vestibular Deficiency
Long Term Outcomes After Vestibular Implantation
Although cochlear implants can restore hearing to individuals who have lost cochlear hair cell function, there is no widely available, adequately effective treatment for individuals suffering chronic imbalance, postural…
- Conditions
- Bilateral Vestibular Hypofunction, Bilateral Vestibular Deficiency, Bilateral Vestibulopathy, Gentamicin Ototoxicity
- Trial name
- NCT06500975
- Testing
- Labyrinth Devices MVI™ Multichannel Vestibular Implant System
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Johns Hopkins University