Clinical trials: Bioavailability of Carotenoids
Absorption, Metabolism and Excretion in Healthy Volunteers, Bioavailability and AUC
Bioavailability Trial
Carrot is a unique vegetable owing to the availability of bioactive compounds polyacetylenes (PA) as well as carotenoids present in it.
- Trial name
- NCT06686004
- Testing
- Carrots
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Biological Availability of Vitamins and Micronutrients
Effect of Genetic Variants on Fat-soluble Vitamin Bioavailability
The aim was to identify minor genetic variations (single nucleotide polymorphisms) that explain the interindividual variability in bioavailability of fat soluble micronutrients (fat soluble vitamins and carotenoids).
- Trial name
- VITAGENES (NCT02100774)
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Bioavailability of Carotenoids
Human Lycopene and Beta-cryptoxanthin Absorption From Citrus Fruit
The goal of the research study is to measure and compare the absorption of equivalent amounts of beta-cryptoxanthin and Iycopene provided in citrus fruit.
- Trial name
- NCT02348164
- Testing
- Pink grapefruit first followed by tangerines two weeks later, Tangerines first followed by pink grapefruit two weeks later
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Biological Availability
Bioavailability of Carotenoids Present in Mamey Sapote (Pouteria Sapota (Jacq.) H. E. Moore & Stearn) Fruit
The goal of the study is to determine if mamey sapote fruit, rich in rare potentially provitamin A keto-carotenoids, is a good source of vitamin A in humans.
- Trial name
- NCT03873909
- Testing
- Fruit Smoothie, Matrix-Free Shake
- Where
- 2 sites in Costa Rica, Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Healthy, Ileostomy
The STOVITA Study - Bioefficacy of Beta-Carotene in Oil and in a Mixed Diet in Ileostomy Patients
A controlled dietary intervention study will be carried out based on the stable isotope method the investigators have developed to quantify both the absorption of beta-carotene and its bioconversion to retinol in oil and in a…
- Trial name
- NCT00128804
- Testing
- absorption and conversion of beta-carotene in human gastrointestinal (GI) tract
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Healthy
The CARO Study - Bioefficacy of Beta-Carotene in Oil and in a Mixed Diet in Healthy Subjects
A controlled dietary intervention study will be carried out based on the stable isotope method the investigators have developed to quantify both the absorption of beta-carotene and its bioconversion to retinol in oil and in a…
- Trial name
- NCT00128752
- Testing
- absorption and conversion of beta-carotene in human gastrointestinal (GI) tract
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Biological Availability
Dose-response Effects of Soybean Oil in Salad Dressing on Carotenoid/Fat-soluble Vitamin Bioavailability in Salad Vegetables
The objectives will be to evaluate the dose-response between the amount of soybean oil in salad dressing and the absorption of: 1) carotenoids, phylloquinone, and tocopherols in salad vegetables; 2) retinyl palmitate formed from…
- Trial name
- NCT02867488
- Testing
- Soybean oil in salad dressing
- Sponsor
- Iowa State University
Menopause
Impact of Egg Consumption on Carotenoid and Vitamin D Bioavailability in Pre- and Post-menopausal Women
The 2010 Dietary Guidelines for Americans emphasizes consumption of 4.5 cups of fruits and vegetables daily but the average intake of US adults is only 2.6 cups.
- Trial name
- NCT02679794
- Testing
- Egg consumption, Control
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Carotenoid and Flavonoid Absorption
Carotenoid and Flavonoid Absorption From Red and Tangerine-Type Tomatoes
Eating a diet rich in tomatoes has been associated with decreased risk for a variety of diseases. Tomatoes contain red-colored lycopene (one type of pigment in the class of pigments called carotenoids), which has been associated…
- Trial name
- NCT01696773
- Testing
- Tangerine tomato juice, Red tomato juice
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Healthy
Plant Pigments for Human Health: Impact of Lycopene and Anthocyanins on Bioefficacy of Provitamin A Carotenoids From Carrots
The proposed research will help characterize the impact that simultaneous consumption of anthocyanins and carotenoids has on the bioavailability of the provitamin A carotenoids a-carotene and b-carotene and the non-provitamin A…
- Trial name
- NCT05319548
- Testing
- Purple-Red Carrot Juice, Red Carrot Juice, Purple Carrot Juice
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Absorption; Chemicals, Healthy Diet
Influence of Proteins on the Bioavailability of Carotenoids
A postprandial intervention study is conducted on healthy male subjects to evaluate whether the addition of proteins (why protein isolate, soy protein) can help to increase the bioavailability of carotenoids from a tomato/carrot…
- Conditions
- Absorption; Chemicals, Healthy Diet, Metabolism
- Trial name
- CAROPROT (NCT04078646)
- Testing
- Intervention with soy protein isolate, Intervention with whey protein, Intervention without protein addition
- Where
- Luxembourg
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health