Clinical trials: Biochemical Marker
Biochemical Markers
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects
The effect of physical activity on serum cartilage biomarkers is largely unknown. This study is critical to increase our knowledge of the physiological cartilage response to activities of daily living and dynamic tasks by…
- Trial name
- NCT06757699
- Testing
- Walking, Cycling
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kocaeli University
Acute Kidney Injury, Cardiac Disease
New Markers of Cardiac Surgery Related Acute Kidney Injury.
Cardiac surgery related acute kidney injury (CS-AKI) is a clinical problem associated with a cardiopulmonary bypass used during cardiac surgery procedures.
- Trial name
- NCT03860545
- Testing
- urine and blood analysis
- Where
- Poland
- Volunteers
- 88 people
- Sponsor
- Pomeranian Medical University Szczecin
Idiopathic Pulmonary Fibrosis
Correlating Outcomes With Biochemical Markers to Estimate Time-progression in Idiopathic Pulmonary Fibrosis (IPF)
Study purpose: The disease course of idiopathic pulmonary fibrosis (IPF) is variable. During the course of the disease some patients will get better, some will stay the same, and others will get worse.
- Trial name
- COMET (NCT01071707)
- Where
- 9 sites in United States
- Volunteers
- 108 people
- Sponsor
- University of Michigan
Athletic Performance, Soccer
The Effect of a Training Programme in the Variation of Fitness Parameters, Physiological, Hematological and Biochemical Indicators of Soccer Players During the Preseason Period
The goal of this study is to investigate the effects of varying friendly match-play exposure during the late pre-season on physiological, biochemical, and performance adaptations in soccer players.
- Conditions
- Athletic Performance, Soccer, Muscle Damage, Inflammation
- Trial name
- NCT07170930
- Testing
- Friendly Match-Play Exposure: extended vs. limited
- Where
- Greece
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Emmanouil D. Zacharakis
Alzheimer's Disease
European Study of HF0220 in Mild to Moderate Alzheimer's Disease Patients
The purpose of this Phase II study is to evaluate the safety and tolerability of HF 0220 in patients with Alzheimer's disease compared to placebo (inactive substance).
- Trial name
- NCT00357357
- Testing
- HF0220
- Where
- 10 sites in India, Sweden and 1 more
- Volunteers
- 40 people
- Sponsor
- Hunter-Fleming Ltd
Energy Expenditure, Anthropometric Measure
The Effect of Time-Restricted Eating on Nutritional Status
This study was planned to investigate the effect of TRE on the nutritional status and diet quality of individuals and to compare the effects of TRE and energy-restricted diet (ERD) in healthy overweight individuals.
- Conditions
- Energy Expenditure, Anthropometric Measure, Blood Pressure, Biochemical Markers
- Trial name
- TRE (NCT05890391)
- Testing
- Time-Restricted Eating, Energy-Restricted Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Saglik Bilimleri Universitesi
Prostatic Neoplasms
Genetic Analysis of Prostate Cancer to Identify Predictive Markers of Disease Relapse or Metastatic Evolution
Developing a genetic study on localized or locally advanced prostate cancer. The aim of the study is to identify genomic alteration predictive of metastatic recurrence in the context of primary heterogeneity, by using the next…
- Trial name
- CHRU-WCMC (NCT03421015)
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Lille
Coronary Artery Disease, Angina, Stable
Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia
The primary aim is to perform the largest study worldwide to evaluate novel biochemical and electrocardiographic signatures alone as well as in combination with the standard 12-lead exercise ECG in the detection of…
- Conditions
- Coronary Artery Disease, Angina, Stable, Exercise Test, Biological Markers
- Trial name
- BASEL VIII (NCT01838148)
- Where
- Switzerland
- Volunteers
- 4,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Pancreaticoduodenectomy
The Effects of High Dose Pancreatic Enzyme Replacement Therapy After Pancreatoduodenectomy
Up to now, the studies concerning nutritional assessment after pancreatic resection were rare. The low-dose pancreatic enzyme treatment after pancreatectomy showed no significant benefit in terms of nutritional status.
- Trial name
- NCT02127021
- Testing
- Norzyme® 40000 IU
- Where
- 6 sites in South Korea
- Volunteers
- 304 people
- Sponsor
- Seoul National University Hospital
Low Back Pain
Biomarkers of Pain and Stress Perception and Dry Needling Technique Application
The use of the dry needling technique has become widespread in recent years for the treatment of musculoskeletal pain. Although dry needling has been shown to be effective in the treatment of shoulder pain, elbow pain, headache…
- Trial name
- NCT06355752
- Testing
- Dry needling of lumbar iliocostalis muscle
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- University of Alcala
Chronic Infection
Orange Juice Consumption in Patients With Hepatitis C
This study aimed to verify whether orange juice, source of citrus flavonoids and vitamin C, may contribute to the treatment of patients with chronic hepatitis C.
- Trial name
- NCT03026569
- Testing
- Orange juice (500 mL/d)
- Where
- Brazil
- Volunteers
- 43 people
- Sponsor
- São Paulo State University
Myocardial Ischemic Reperfusion Injury
Myocardial Protection and Anesthetic Agents
The aim of this study was to investigate the myocardial protective effects of remifentanil and dexmedetomidine in cardiac surgery.
- Trial name
- NCT02405689
- Testing
- Remifentanil, Dexmedetomidine, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Acute Coronary Syndromes, Flow Mediated Dilation
A Prospective, Single-center, Observational Study Aiming to Assess the Predictive Role of Flow Mediated Dilatation in Acute Coronary Syndromes, Combined With Echocardiographic and Biochemical Indices
A prospective, single-center, observational study aiming to assess the predictive role of flow mediated dilatation in acute coronary syndromes, combined with echocardiographic and biochemical indices.
- Conditions
- Acute Coronary Syndromes, Flow Mediated Dilation, Endothelial Function (FMD)
- Trial name
- FLARE-ACS (NCT06890013)
- Testing
- Observation group
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Axial Spondyloarthritis, Ankylosing Spondylitis
Treat-to-target With Secukinumab in Axial Spondyloarthritis
A study of axSpA and AS receiving Secukinumab in a treat-to-target strategy.
- Trial name
- TRACE (NCT03639740)
- Testing
- Secukinumab 150 milligram [Cosentyx]
- Where
- 10 sites in Denmark
- Volunteers
- 88 people
- Sponsor
- Professor Mikkel Østergaard
Pregnant Woman
Pilot Trial of Hibiscus Drink During Pregnancy (PTHDDP)
The goal of this phase I pilot clinical trial is to evaluate the acceptability, tolerability and effect on blood pressure and biomarkers of Hibiscus sabdariffa drink in pregnant women in the second trimester of pregnancy.
- Trial name
- PTHDDP (NCT07175597)
- Testing
- Hibiscus sabdariffa drink
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- Victor Eduardo Alcantar Rodríguez
Metastasis, Castration-resistant Prostate Cancer
Prognostic Role of Free Psa Ratio at Biochemical Recurrence After Radical Treatments for Prostate Cancer
Measurement of Free PSA ratio in patients after definitive radical treatment for prostate cancer, and assessment of whether post-treatment free PSA ratio can function as a biomarker for advanced disease in prostate cancer…
- Conditions
- Metastasis, Castration-resistant Prostate Cancer, Death
- Trial name
- FPSAR (NCT03927287)
- Testing
- Free PSA ratio test in patients after definitive treatment for localized prostate cancer
- Where
- Canada
- Volunteers
- 822 people
- Sponsor
- Rabin Medical Center
Primary Prevention
Genetical, Anthropometrical and Biochemical Factors Influencing High Risk Subclinical Atherosclerosis
Subclinical atherosclerosis is the atherosclerotic process identified before clinical symptoms and thus it can be a useful marker of future cardiovascular events. It can be evaluated by many methods.
- Trial name
- NCT02487615
- Where
- 2 sites in Brazil
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Overweight and Obesity
Metabolism Effects of Artificially Sweetened Beverages Restriction
The consumption of artificially sweetened beverages increases glucose and insulin concentrations in blood, body weight and waist circumference.
- Trial name
- NCT03679689
- Testing
- artificially sweetened beverages
- Where
- Mexico
- Volunteers
- 45 people
- Sponsor
- Monica Flores-Muñoz
End-stage Heart Failure, Left Ventricular Assist Device
LVAD Index and Clinical Outcomes in Continuous-Flow LVAD Patients
This single-center, observational study evaluated the LVAD index, defined as device-estimated pump flow divided by body surface area, in adult patients supported with continuous-flow left ventricular assist devices.
- Conditions
- End-stage Heart Failure, Left Ventricular Assist Device, Mechanical Circulatory Support
- Trial name
- LVAD-INDEX (NCT07633535)
- Testing
- HeartWare Ventricular Assist Device, HeartMate 3 Left Ventricular Assist Device
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Gaziantep City Hospital
Chronic Kidney Diseases
Effects of Cinnamomum Supplementation in Chronic Kidney Disease Patients
Patients with chronic kidney disease (CKD) experience many complications related to inflammation and oxidative stress that are closely related to the progression of kidney failure and increased mortality.
- Trial name
- NCT06286735
- Testing
- cinnamomum
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense