Clinical trials: Biocompatibility
Hyaluronic Acid (HA)
A Comparative Clinical Assessment of Adjunctive Hyaluronic Acid With 3D Printed Versus Milled CAD CAM Provisional Dental Restorations on Active Periodontal Status and Surface Roughness and Biocompatibility
A Comparative Clinical Assessment of Adjunctive Hyaluronic Acid with 3D Printed Versus Milled CAD CAM Provisional Dental Restorations on active Periodontal status and Surface Roughness and biocompatibility (A Randomized…
- Trial name
- NCT07625839
- Testing
- commonly used hyaluronic Acid with both procedures 3D Printed Versus Milled CAD CAM Provisional Dental Restorations
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Health, Pediatric Dentistry
Periodontal Biocompatibility of Pediatric Crowns
Different full-coverage crown materials are widely used in pediatric dentistry for the restoration of primary teeth with extensive substance loss.
- Conditions
- Oral Health, Pediatric Dentistry, Stainless-steel Crown, Matrix Metalloproteinase
- Trial name
- NCT07611292
- Testing
- Clinical periodontal assessments, GCF measurements and sample collection
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Non-carious Cervical Lesions
Release of Organic Components of a GIOMER in Non-carious Cervical Lesion Restorations
To evaluated the clinical performance of composite resin restorations, considering also the evaluation of release of resin components into saliva and the presence cytokines in gingival fluid.
- Trial name
- NCT03637946
- Testing
- Device: SHOFU beautifil II LS
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
HGF, Fibroblast
Effects of Chlorhexidine on Human Gingival Fibroblasts
This prospective in vitro study aims to evaluate the effects of two chlorhexidine-based mouthwash formulations on the survival and function of human gingival fibroblasts (hGFs).
- Conditions
- HGF, Fibroblast, Chlorhexidine, Cytotoxicity
- Trial name
- NCT07669636
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Keratitis
Study of the Presence and Extent of Corneal Disturbance Associated With B+L Biotrue MPS Used With B+L PureVision Lenses
Corneal epithelial disruption, commonly termed "corneal staining" has been frequently associated with contact lens wear. Previous research has demonstrated higher levels of observed corneal staining when certain combinations of…
- Trial name
- NCT01268306
- Testing
- B+L Biotrue MPS and B+L PureVision
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Epstein, Arthur B., OD, FAAO
Peri-implant Soft Tissue Healing
Soft Tissue Response and IL-1β Levels Around CAD/CAM-Milled vs 3D-Printed PMMA Healing Abutments
This study looked at how the gums and tissues around dental implants heal when using two different types of temporary healing caps made of PMMA (a common dental material).
- Trial name
- NCT07287722
- Testing
- CAD/CAM-Milled PMMA Healing Abutment, 3D-Printed PMMA Healing Abutment
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ali Hassan Eid Toto
Materials Testing
RCT to Evaluate Biocompatibility of Resin-based Dental Materials
In this randomized clinical trial, the bio-compatibility of 2 materials used for dental restorations will be compared: glass-ionomer vs resin-based composites.
- Trial name
- NCT02874625
- Testing
- Dental restoration
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven