Clinical trials: Biologic Implant
Inguinal Hernia
Neo-angiogenesis in Inguinal Henia Implant ProFlor
The investigation is aimed at specifically demonstrating the ingrowth of newly formed vascular elements within ProFlor, a 3D dynamic responsive implant for inguinal hernia repair
- Trial name
- NCT04541316
- Testing
- ProFlor inguinal hernia device
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Implant Therapy
Osseodensification Versus Conventional Drilling Effect on Implant Stability
A total of 80 implants were placed in the posterior region of the maxilla in 40 patients in a split-mouth design. Bone quality was classified into type I, II, III, IV, or V as assessed preoperatively on cone-beam computed…
- Trial name
- NCT05824949
- Testing
- osseodensification drilling, conventional drilling
- Where
- Palestinian Territories
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Arab American University (Palestine)
Completely Edentulous Maxilla
Assessment of Novaloc and Locator Attachment Systems
The aim of the current study is to assess the effect of two types of attachments (Locator, Novaloc) on the supporting structures both mechanically using stress strain analysis and biologically through measuring bone height using…
- Trial name
- NCT06011031
- Testing
- Novaloc attachment, Locator attachment
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Inguinal Hernia
Neo-nervegenesis in Inguinal Hernia Implant ProFlor
The investigation is aimed at specifically demonstrating the ingrowth of newly formed nervous elements within a 3D dynamic responsive implant for inguinal hernia repair.
- Trial name
- NCT04171102
- Testing
- ProFlor Hernia implant
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Tooth Loss
Biological Specifications for Denture Designs
The primary term goal of these research efforts has been to enhance the functional status, comfort and quality of life of edentulous patients by evaluating clinical procedures, denture designs and adjunctive therapies based upon…
- Trial name
- NCT00018512
- Testing
- Implant-supported denture
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Dental Restoration, Dental Implant
Prosthetic Outcomes and Clinical Performance of Implant Supported Zirconia Crowns
To compare biological, technical, radiographic, and patient-reported outcomes of two types of monolithic zirconia crowns screw-retained to implant.
- Trial name
- NCT06417632
- Testing
- Graded Zirconia Crown, Conventional Zirconia Crown
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Implant Therapy, Biological Width
Histological Analysis of Peri-implant Soft Tissue
The aim of this study is to evaluate the histologically analysis in humans and the orientation of collagen fibers around screw-less, morse taper implant-abutment connection.
- Trial name
- NCT06862505
- Testing
- Biopsy
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Thromboembolism, Bleeding
Anticoagulant After Implantation of Biological Aortic Valve Comparing With Aspirin
The optimal medical strategy for prevention of thromboembolic events after bioprosthetic aorta valve replacement (BAVR) remains controversial.
- Trial name
- NCT01452568
- Testing
- Aspirin, Warfarin
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Alveolar Bone Loss
Biologically Oriented Alveolar Ridge Preservation (BARP) With and Without Advanced Platelet-Rich Fibrin Plus (A-PRF+)
Twenty patients were selected from the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University seeking for extraction of non-restorable maxillary premolar teeth prior to…
- Trial name
- NCT07869082
- Testing
- Socket preservation by deproteinized bovine bone graft, socket preservation by deproteinized bovine bone graft mixed with advanced PRF+
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Peri-Implantitis
Efficacy of Er: YSGG Laser in Treatment of Peri-implantitis
This study will be carried out to evaluate the efficacy of Er: YSGG laser on oral biofilm removal from implant surface in various peri-implant defect morphology in the treatment of peri-implantitis as a primary objective.
- Trial name
- NCT05137821
- Testing
- Er: YSGG laser, no therapy
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Post-osseointegration Biological Failure of Dental Implant, Alveolar Bone Loss
The Influence of Mucosal Tissue Thickness on Soft and Hard Tissue Changes Around Implants
Crestal bone and soft tissue stability around implants is an important issue in implant dentistry. Initial vertical mucosal tissue thickness was shown to be one of the factors having impact on bone stability.
- Trial name
- NCT02580721
- Testing
- Dentsply Astra Tech Implant System EV
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Periodontitis, Peri-implant Mucositis
Biological Responses Affecting Early-stage Dental Implant Placement in Patients With History of Periodontitis
This prospective parallel, double-blind, four-arm randomised controlled clinical study is planned to assess the difference in the level of the inflammatory biomarkers expressed following the placement of the first dental implant…
- Conditions
- Periodontitis, Peri-implant Mucositis, Peri-Implantitis
- Trial name
- NCT05834946
- Testing
- Megagen implant placement, Biomate-Swiss implant
- Where
- Malaysia
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Edentulism, Dental Implants
Dental Implant Healing With TNF-Alpha Inhibitors
The goal of this pilot study is to learn about healing after dental implant placement in patients taking a class of biologic drug called Tumor Necrosis Factor or TNF-alpha antagonist or inhibitor.
- Conditions
- Edentulism, Dental Implants, TNF-alpha Inhibitors
- Trial name
- NCT06538870
- Testing
- Placement of dental implants
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Implant Complication
Prosthetic and Biological Complications of Implant Supported Prostheses
complications of implant retained prostheses
- Trial name
- NCT05297253
- Testing
- telescopic overdenture
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Dental Implant, Primary Sjögren Syndrome
Prognosis of Dental Implants in Patients With Primary Sjögren's Syndrome
Primary Sjögren's Syndrome (PSS) is a chronic autoimmune inflammatory disease primarily involving the salivary and lacrimal glands. Few data exist regarding survival and success rate of dental implants in patients with PSS.
- Trial name
- NCT04960605
- Testing
- Dental implants
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Implants
Clinical and Radiographic Outcomes of Implant-supported Prostheses With Cantilever Extensions After 10 Years of Function
A retrospective examination was performed on patients who had received treatment with dental implants supporting a prosthesis with a cantilever extension for at least 10 years of function.
- Trial name
- Cantilevers (NCT06534398)
- Testing
- Dental implant prosthesis with cantilever extension
- Where
- Greece
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Dental Implant Failed
Immediate Implant Placement With Subepithelial Connective Tissue Grafting and Probiotics
The present study aims to evaluate and compare the clinical, radiographic, and biological peri-implant tissue outcomes of platelet-rich fibrin versus probiotics as adjuncts to immediate implant placement combined with…
- Trial name
- NCT07596758
- Testing
- Platelet-Rich Fibrin, Probiotics
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Dental Implant
Impact of Biological Factors on Dental Implant
The goal of this randomized controlled trial is to compare the response of different bone densities to treatment with Platelet Rich Fibrin (PRF) in patients who need treatment with dental implant.
- Trial name
- NCT06037070
- Testing
- Platelet Rich Fibrin
- Where
- Iraq
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Edentulism
Evaluation of the ACE Dental Implant
Dental implants are small metal posts that look like miniature screws. They are surgically implanted into the jawbone where they serve as substitute tooth roots.
- Trial name
- ACE-2005 (NCT00641576)
- Testing
- ACE CONNECT Endosseous dental implant
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Dental Implant, Osseointegration
Assessment of Early Healing Period of Dental Implants
This prospective cohort study aimed to evaluate, clinically, radiographically, and digitally, the volumetric changes occurring during the early healing period after implant treatment in patients with tooth loss in the posterior…
- Conditions
- Dental Implant, Osseointegration, Biological Width
- Trial name
- NCT06554444
- Testing
- Dental Implant Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University