Clinical trials: Biological Aging Marker
Brain, Aging
Biobank and Brain Health in Bordeaux.
B cube is a new generation cohort to study the determinants and natural history of brain aging, using molecular epidemiology, in a representative sample (N=2000) of the general population from the age of 55 (the approximate age…
- Conditions
- Brain, Aging, Cognitive Aging, Immunosenescence
- Trial name
- B-cube (NCT05322343)
- Testing
- Questionnaires, Fasting blood sampling., Saliva collection and nasal or nasopharyngeal swab
- Where
- France
- Volunteers
- 2,050 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Skin Ageing, Healthy Ageing
Effects of a Multi-Targeted Oral Supplement on Skin, Hair, Sleep, Energy, Cognition, Libido and Epigenetic Biological Clock Age
This study evaluated the effects of a daily oral supplement regimen (Advanced ID Brain, Heart and Eye Omega Gel Capsules taken with Advanced ID Longevity and Collagen Complex Powder) on measures of skin condition, hair, sleep…
- Conditions
- Skin Ageing, Healthy Ageing, Effect of Oral Nutritional Supplementation on Skin, Hair, Sleep, Energy, Cognition and Sexual Wellbeing in Healthy Adults, Longevity
- Trial name
- IDF-AID-1 (NCT07827651)
- Testing
- Advanced ID
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- IDI Skincare Limited
Aging, Aging, Healthy
Emotional Well-being and Measures of Healthy Aging
This randomized control study is designed to understand the role of a positive psychology intervention (PARK: Positive Affect Regulation sKills) in biological aging and well-being.
- Conditions
- Aging, Aging, Healthy, Aging Well, Aging, Biological
- Trial name
- NCT07334106
- Testing
- Positive Emotion Skills Intervention
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Metformin, Aging
Pilot Study on Evaluating the Geroprotective Effect of Metformin
The objective of this research is to assess the efficacy of oral metformin in mitigating the aging process in middle-aged and elderly males, to pinpoint sensitive indicators of human senescence, and to offer innovative frameworks…
- Trial name
- AGE-M (NCT06459310)
- Testing
- Metformin Hydrochloride tablet
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Fragility
Biological Markers of Functional Effects of Physical Activity in an Elderly Population
Circulating biomarkers are promising tools for the early diagnosis of aging-associated pathologies. Inflammation and immunity are associated with the risk of sarcopenia and frailty in elderly patients.
- Trial name
- BIO-APAS (NCT04080063)
- Testing
- adapted physical activity
- Where
- France
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Biological Aging
The Inspire Bio-resource Research Platform for Healthy Aging INSPIRE Platform
Since aging is a systemic (not organ-specific) phenomenon, the main objective of Inspire Bio-resource Research Platform for Healthy Aging is to build a comprehensive research platform gathering biological, clinical (including…
- Trial name
- INSPIRE (NCT04224038)
- Testing
- The Inspire Bio-resource Research Platform for Healthy Aging
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Aging, Aging Well
100-Year Human Aging Study
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed clinical sites, mobile clinical sites, and an online participation pathway (current and future) to undergo…
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality
- Trial name
- NCT07563777
- Testing
- Comprehensive Multi-System Clinical Screening
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Aging
Effect of Aging on Haemostasis Parameters
Aging is an independent risk factor, without any clear explanation. The primary aim of the study is to depict the effect of aging on the coagulation fibrinolysis parameters and microparticles.
- Trial name
- NCT00299624
- Where
- 2 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hopital Lariboisière
Aging
Morning-Evening Specific Longevity Food Supplement
The use of food supplements with the aim of increasing longevity in the general population is rapidly increasing, while high-quality clinical evidence on the efficacy of comprehensive formulations and their impact on biomarkers…
- Trial name
- NCT07416396
- Testing
- Morning- and evening-specific compound food supplement, Control
- Where
- Slovenia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Poverty, Tax Policy
Effect of EITC on Biological Markers of Aging, Health and Mortality
Paycheck Plus (PP) is a randomized controlled experiment (RCT) that explores the health and longevity effects associated with increasing the Earned Income Tax Credit (EITC).
- Trial name
- PaycheckPlus (NCT03226548)
- Testing
- Paycheck Plus
- Where
- United States
- Volunteers
- 1,350 people, healthy volunteers welcome
- Sponsor
- Columbia University
Healthy Aging, Biological Aging
Ageing BIOmarker Study in Singaporeans
The Ageing BIOmarker Study in Singaporeans (ABIOS) aims to understand the biological aging processes and how they affect health among people in Singapore. As people grow older, their risk of developing chronic diseases increases.
- Conditions
- Healthy Aging, Biological Aging, Lifestyle Factors
- Trial name
- ABIOS (NCT06555978)
- Where
- Singapore
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Alzheimer Disease, Mild Cognitive Impairment
Korean Brain Aging Study for Early Diagnosis and Prediction of Alzheimer's disease2 (KBASE2)
The KBASE2 is the second phase of the KBASE project, which consists of roll-over participants from the first phase of the KBASE as well as newly enrolled participants with varying degrees of cognitive functions (e.g.
- Trial name
- KBASE2 (NCT05138263)
- Where
- 2 sites in South Korea
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Aging, Elderly
Successful Aging and Age-related Decline
Recent studies have shown promising cognitive and physical interventions aimed at slowing down ageing-related declines in quality of life, but they lack strong ecological validity (brief durations, unrealistic goals, no…
- Conditions
- Aging, Elderly, Cognitive Decline, Physical Decline
- Trial name
- MyAgeWell (NCT06376656)
- Testing
- Cognitive stimulation, Physical activity
- Where
- Malaysia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sunway University
Healthy
The Use of Aging Biomarkers in Saliva, Based on DNA Methylation Status in Elovl2 to Predict Biological Age
There is a big change in our understanding of aging in recent years. Recent researches has revealed clock-like patterns of epigenetic change across in humans. The aging involves a timed epigenetic reprogramming.
- Trial name
- NCT03734419
- Volunteers
- healthy volunteers welcome
- Sponsor
- HKGepitherapeutics
Aging
Sex-Speciffic Longevity Food Supplements
The use of food supplements with the aim of increasing longevity in the general population is rapidly increasing, while high-quality clinical evidence on the efficacy of comprehensive formulations and their impact on biomarkers…
- Trial name
- NCT07404449
- Testing
- compound food supplements - female specific, compound food supplements - male specific
- Where
- Slovenia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Aging, Mortality
Human Observatory Study
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level.
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy
- Trial name
- HOS (NCT07646782)
- Testing
- Multi-Domain Ecological and Clinical Data Linkage
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Healthy Aging, Ageing Well
Effects of an Omega-3 Fatty Acid-based Supplement on Healthy Ageing
The goal of this randomised, double-blind placebo controlled trial is to explore tolerability and the effects of a new omega-3 fatty acid-based supplement on biological and clinical aspects relevant for healthy ageing.
- Trial name
- NCT06150261
- Testing
- AvailOm
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Healthy Aging, Biomarkers
RUSS-AGE: Creating of a Biological Age Calculator and Study of Aging Phenotypes in the Russian Population
This is a multi-center, cross-sectional, observational study aimed at developing biological age calculators specifically for the Russian population investigating various aging phenotypes.
- Trial name
- RUSS-AGE (NCT07574359)
- Where
- Russia
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Pirogov Russian National Research Medical University
Taurine, Aging, Biological
Effects Of Daily Taurine Intake For 6 Months On Biological Age and Body Metabolism Indicators As Well As Physical Fitness In 55-75-year-old Women And Men
The goal of this clinical trial is to investigate the effect of taking 4 grams of taurine by older adults on aging processes over a period of 6 months.
- Conditions
- Taurine, Aging, Biological, Physical Activity, Metabolic Health
- Trial name
- TauAge (NCT06613542)
- Testing
- 4g of taurine daily
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Phenotypic Age Acceleration, Biological Aging Marker
Phenotypic Age Acceleration (PhenoAgeAccel) for Joint Prediction of Disease Risk, Mortality Risk, Life Expectancy, and Disease-Free Healthspan in Major Chronic Diseases
The goal of this observational study is to learn about the ability of Phenotypic Age Acceleration (PhenoAgeAccel) to predict four key health outcomes in Chinese people with or at risk of major chronic diseases: the risk of…
- Conditions
- Phenotypic Age Acceleration, Biological Aging Marker, Mortality Risk Prediction, Disease Risk Prediction
- Trial name
- NCT07595094
- Testing
- No Intervention (Observational Study)
- Where
- China
- Volunteers
- 2,000,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University