Clinical trials: Birth Disorder
Pregnancy, Anxiety
Childbirth Education Pilot Study
This study aims to investigate the effects of mindfulness training on prenatal maternal anxiety using a randomized controlled trial (RCT).
- Trial name
- NCT04327557
- Testing
- MBCP Childbirth Education Course, Non-MBCP Childbirth Education Course
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Preterm Infants
How Accurate INFANIB is Among Hospitalized Preterm Infants
Reliability of infant neurological international battery (INFANIB) among hospitalized preterm infants will be checked. This study will mainly focus on test-retest reliability.
- Trial name
- NCT04800328
- Where
- India
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Premature
Anemia of Prematurity and Hemodynamics
The aim of this work to study the hemodynamic changes accompanying anemia of prematurity in neonates with gestational age ≤32 weeks and the effect of its treatment on hemodynamics.
- Trial name
- NCT05496400
- Testing
- Echocardiographic and Doppler studies
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Marwa Mohamed Farag
Hiv
Pharmacy-based PrEP Delivery in Kenya
A cluster-randomized control trial (cRCT) testing different cost-sharing models for the delivery of HIV pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) services at private pharmacies in Kenya.
- Trial name
- NCT05842122
- Testing
- Client-sustained delivery of pharmacy PrEP/PEP, Implementor-sustained delivery of pharmacy PrEP/PEP, Counselor-supported delivery of pharmacy PrEP/PEP
- Where
- 2 sites in Kenya
- Volunteers
- 5,808 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Preterm Birth, Hypertension
Young Adult Cardiovascular Health sTudy
The purpose of this study is to understand more about why young people who were born prematurely may have increased risk of high blood pressure and lower cardiovascular exercise capacity.
- Trial name
- YACHT (NCT02103231)
- Where
- United Kingdom
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Twin; Complicating Pregnancy, Advanced Maternal Age Pregnancy
Birth Cohort Study of China Medical University
The CMUBCS is a birth cohort study located in Shenyang, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology.
- Conditions
- Twin; Complicating Pregnancy, Advanced Maternal Age Pregnancy, Scarred Uterus, Overweight and Obesity
- Trial name
- NCT03561766
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Preeclampsia, Preterm Birth
Biobank on Prematurity, Preeclampsia and Other Pregnancy Complications
The Biobank includes data and biological specimens of women from three original studies: 1) First-trimester Prediction of Preeclampsia (PREDICTION Study, NCT02189148), 2) Pre-Eclampsia And growth Retardation, an evaluative…
- Conditions
- Preeclampsia, Preterm Birth, Pregnancy Complications, Fetal Anomalies
- Trial name
- NCT02744365
- Testing
- Observational
- Where
- Canada
- Volunteers
- 7,845 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Mother, Premature
The Effect of the Mobile Application Developed for Home Care of Preterm
mobile application will be developed to support the post-discharge home care of mothers of premature babies. With the developed mobile application, the effect of the education given to the mothers on the knowledge and skills of…
- Conditions
- Mother, Premature, Education, Home Care
- Trial name
- NCT05438056
- Testing
- education with mobile application
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ankara University
Post Partum Hemorrhage
Oxytocin vs Carbetocin at Cesarean Delivery in Women With Morbid Obesity
Postpartum hemorrhage (PPH) is a major cause of maternal death worldwide. Oxytocin is the most commonly used uterotonic drug for the active management of third stage labor, to reduce the risk of PPH and help deliver the placenta.
- Trial name
- NCT04902729
- Testing
- Carbetocin, Oxytocin
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pregnancy, Pregnancy Complications
PregSource: Crowdsourcing to Understand Pregnancy
PregSource uses a crowd-sourcing approach, asking pregnant women to enter information regularly and directly about their pregnancies throughout gestation and the early infancy of their babies into online surveys and trackers via…
- Conditions
- Pregnancy, Pregnancy Complications, Morning Sickness, Diabetes, Gestational
- Trial name
- PregSource (NCT02577536)
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 2,359 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Mild Cognitive Impairment, Cognitive Impairment
SNIFF - 3-Week Aptar CPS Device
The SNIFF 3-Week Aptar Device study will involve using a device to administer insulin or placebo through each participant's nose or intra-nasally. Insulin is a hormone that is produced in the body.
- Conditions
- Mild Cognitive Impairment, Cognitive Impairment, Alzheimer Disease, Early Onset
- Trial name
- NCT05006599
- Testing
- Insulin (Humulin® R U-100), Aptar Pharma CPS Intranasal Delivery Device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Impaired Glucose Tolerance, Fetal Macrosomia
Treatment of Impaired Glucose Tolerance in Pregnancy
The purpose of this study is to evaluate if treatment (insulin or diet) of pregnant women with impaired glucose tolerance (75-g OGTT with a fasting P-gluc <7.0 mmol/l and 2 h P-gluc >10.0 and <12.2 mmol/l) close to normoglycemia…
- Trial name
- TIP (NCT00625781)
- Testing
- Insulin aspart and Insulin human (isophane)
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Hepatitis C, Chronic Hepatitis C
Birth-Cohort Evaluation to Advance Screening and Testing for Hepatitis C
The Birth-Cohort Evaluation to Advance Screening and Testing for Hepatitis C (BEST-C) compares the effectiveness of the birth cohort HCV screening strategy with the current risk-based screening approach to detect previous…
- Trial name
- Best-C (NCT02123212)
- Testing
- Mailer, In-person recruitment, EHR Alert
- Where
- 3 sites in United States
- Volunteers
- 29,607 people, healthy volunteers welcome
- Sponsor
- National Opinion Research Center
Post Traumatic Stress Disorder, Childbirth Experience
"Connected Caesarean Section": Creating a Virtual Link Between Mothers and Their Infants to Improve Maternal Childbirth Experience: A Pilot Trial
One third of mothers rate their childbirth as traumatic. The prevalence of childbirth-related posttraumatic stress disorder (CB-PTSD) is of 4.7% and the prevalence of childbirth-related posttraumatic stress symptoms (CB-PTSS) of…
- Trial name
- e-motion-pilot (NCT05319665)
- Testing
- Head-mounted display
- Where
- Switzerland
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Infection, Bacterial, Infection, Fungal
Point-of-care Tests for Bacterial Vaginosis and Candidosis
Vaginal infection in early pregnancy is associated with an increased risk of spontaneous preterm delivery and late miscarriage. Most studies presume that vaginal infections are responsible for up to 40% of preterm birth.
- Conditions
- Infection, Bacterial, Infection, Fungal, Preterm Birth
- Trial name
- NCT04287504
- Testing
- SavvyCheck Vaginal Yeast Test, OSOM BVBLUE Test
- Where
- Austria
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Neonatal Hypoglycemia, Prematurity
Late Preterm Corticosteroids and Neonatal Hypoglycemia
This is a prospective randomized controlled trial investigating the timing of betamethasone administration in late preterm infants in relation to delivery and impact on neonatal hypoglycemia.
- Trial name
- NCT04869709
- Testing
- Betamethasone Sodium Phosphate
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Brain DHA Delivery and Alzheimer's Disease Risk
DHA Brain Delivery Trial
Carrying the APOE ɛ4 allele is the strongest genetic risk factor for developing Alzheimer's disease. The goal of this project is to identify whether carrying the APOE ɛ4 allele is associated with reduced delivery of DHA to the…
- Trial name
- PreventE4 (NCT03613844)
- Testing
- DHA
- Where
- United States
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Congenital Heart Disease
Genetics of Congenital Heart Disease
Congenital heart disease (CHD) is the most common type of birth defect but the cause for the majority of cardiac birth defects remains unknown.
- Trial name
- NCT01192048
- Testing
- Blood Sample Collection
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Hepatitis B, Immunization; Infection
Hepatitis B Birth Dose for Newborns
With 2.5% prevalence in general population, Pakistan is an intermediate endemicity country for hepatitis B. However, wide disparity exists across the country as disease prevalence in general population soars as high as 14% in…
- Trial name
- HepB-BirD (NCT04870021)
- Testing
- recombinant hepatitis B vaccine ENGERIX 10 micrograms (µ gm),, Short text messages and calls to parents for compliance to routine immunization schedule
- Where
- Pakistan
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Quaid-e-Azam University
Preterm Birth, Prenatal Care Late
This Study Was to Investigate the Efficacy of Fetal Right Heart Doppler Findings in Determination of Pulmonary Maturity
Objective: The aim of this study was to investigate the efficacy of fetal right heart doppler findings in determination of pulmonary maturity.
- Conditions
- Preterm Birth, Prenatal Care Late, Preterm Labor
- Trial name
- NCT04296591
- Testing
- fetal heart doppler findings
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
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