Clinical trials: Bispectral Index Monitoring
Mindfulness, Dental Implant
The Effect of Mindfulness Meditation During Dental Implant Surgery
The aim of this pioneer study was to evaluate the efficacy (heart rate value, blood pressure, oxygen saturation, cortisol levels, BIS monitoring, patients' anxiety) of Mindfulness Meditation as a sedative technique during dental…
- Trial name
- NCT05748223
- Testing
- Mindfulness Meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Anesthesia
Electroencephalogram (EEG) in General Anaesthesia - More Than Only a Bispectral Index (BIS)
Processed electroencephalogram (EEG) monitors are routinely used in addition to clinical parameters to assess the depth of anaesthesia during general anaesthesia.
- Trial name
- NCT04105660
- Testing
- Training for EEG monitoring, Standard monitoring
- Where
- 4 sites in Switzerland
- Volunteers
- 232 people
- Sponsor
- University Hospital, Basel, Switzerland
General Anesthesia
Comparison of Two Electroencephalograms (EEG) Monitors in Patients Undergoing General Intravenous Anesthesia
Quantium Medical Company has an ElectroEncephalograph-based (EEG-based) algorithm with two outputs: qCON for unconsciousness and qNOX for anti-nociception.
- Trial name
- Bis-qCON-IV (NCT03753217)
- Testing
- qCON Monitor
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Hopital Foch
Anesthesia
Comparative Population Pharmacodynamic Modeling for Sevoflurane Effects Using ADMS and Bispectral Index
The investigators want to compare the performance of anesthetic depth monitoring for sedation (ADMS) to the bispectral index (BIS) as electroencephalographic measures of sevoflurane effect using two combined sigmoidal Emax models…
- Trial name
- NCT03069456
- Testing
- BIS, ADMS
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chonnam National University Hospital
Cerebral Palsy
Validity of Bispectral Index Monitoring During Deep Sedation
During Intramuscular botulinum toxin injections for children with cerebral palsy, immobility is essential to inject botulinum toxin to the right muscle.
- Trial name
- NCT02096549
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yeungnam University College of Medicine
Postoperative Delirium, Cognitive Impairment
Predictive Efficacy of Ratio of Median Frequency to Spectral Edge Frequency Used in the Depth of Anaesthesia Monitoring on Post-operative Cognitive Functions
The primary objective of this observational study is to evaluate the effectiveness of preoperative anaesthesia depth monitoring parameters in predicting postoperative cognitive functions in non-cardiac adult patients.
- Trial name
- NCT06644209
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Ankara University
General Anesthesia
Multimodal Monitoring During General Anesthesia in ENT Surgery
This study evaluated whether using several monitoring methods together during general anesthesia could improve patient safety and help anesthesiologists adjust medication doses in adults undergoing ear, nose, and throat (ENT)…
- Trial name
- NCT07895836
- Testing
- Multimodal Anesthesia Monitoring (BIS, SPI, TOF), Standard Anesthesia Monitoring
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Barbara Verro
Disorder; Mental, Sedative, Depressed Level of Consciousness
BIS Monitoring to Detect Deep Sedation
Studies have shown that prolonged deep sedation is associated with adverse clinical outcomes in adult intensive care unit (ICU) patients.
- Conditions
- Disorder; Mental, Sedative, Depressed Level of Consciousness, Mechanical Ventilation Complication, Psychosis Associated With Intensive Care
- Trial name
- NCT02203344
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Capital Medical University
Neurophysiology
Quantitative Electroencephalogram and Bispectral Index Brain Mapping During Propofol vs Sevoflurane General Anesthesia
General anesthesia interferes with the whole cerebral cortex at different levels. The goal was to investigate the impact of general anesthesia on different regions of the cerebral cortex by recording the brain's…
- Trial name
- NCT05102422
- Testing
- Propofol 1 % Injectable Suspension, Sevoflurane inhalant product
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pierre Pandin
Movement Disorders, Depth of Anesthesia Monitors
BIS and Entropy in Deep Brain Simulation
The main objective of the study is to determine whether depth of anesthesia (DOA) monitoring such as Bispectral Index (BIS) and entropy are accurate in patients with neuro-psychological conditions such as Parkinson's disease by…
- Trial name
- NCT02386995
- Testing
- BIS monitor, Entropy monitor
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Sedation
Sedation of Advanced Endoscopic Procedure
To evaluate the impacts of target-control infusion (TCI) and bispectral index (BIS) monitoring during advanced endoscopic procedure.
- Trial name
- NCT03172078
- Testing
- advanced endoscopic procedure
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Depression
Investigation on the Value of Bilateral Index (BIS) Monitoring for Magnetic Seizure Versus Electroconvulsive Therapy
Electroconvulsive therapy (ECT) has been shown to be an effective treatment for patients suffering from depression, who do not respond to medical treatment.
- Trial name
- NCT01318018
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bonn
General Anesthesia
Comparative Analysis of Phase Lag Entropy (PLE) and Bispectral Index (BIS) as an Anesthetic Depth Indicator
The aim of this comparative analysis is to evaluate the reliability of PLE value as an anesthetic depth indicator
- Trial name
- NCT03424720
- Testing
- PLE and BIS
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Hallym University Medical Center
Anesthesia
Research on Anesthesia Depth Control Strategy Based on Continuous and Non-invasive Monitoring of Exhaled Breath
This study aims to propose a strategy for controlling the depth of anesthesia based on continuous and non-invasive monitoring of exhaled breath: BIS value during intravenous-inhalation combined anesthesia is predicted according…
- Trial name
- NCT07272044
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Anesthesia, General
Use of Bispectral Index (BIS) for Monitoring of Total Intravenous Anaesthesia in Pediatric Patients
The objective of the study is to determine wether the use of the Bispectral Index Monitor (BIS) as a method to guide anaesthesia for children in different groups of age, undergoing ear nose and throat surgery anaesthetized with…
- Trial name
- NCT01043952
- Testing
- Propofol, Remifentanil, Bispectral Index Monitor
- Where
- Denmark
- Volunteers
- 157 people
- Sponsor
- Aalborg University Hospital
Cardiac Surgery Patients
Bilateral Bispectral Index (BIS)-Monitoring in Cardiac Surgery Patients
The bispectral index (BIS) is derived from a single-channel electroencephalogram (EEG) and provides information on the anaesthetic depth.
- Trial name
- NCT01048775
- Where
- Germany
- Volunteers
- 87 people
- Sponsor
- University Hospital, Bonn
Cerebral Aneurysm
NIRS and BIS Monitoring During Cerebral Aneurysm Coiling
This prospective observational study aims to evaluate the effectiveness of Near-Infrared Spectroscopy (NIRS) and Bispectral Index (BIS) monitoring during endovascular coil embolization of cerebral aneurysms under general…
- Trial name
- NIRSBIS-ANEUR (NCT07438275)
- Testing
- Near-Infrared Spectroscopy (NIRS) and Bispectral Index (BIS) Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Dokuz Eylul University
Awareness During General Anesthesia
Bispectral Index (BIS) Versus Electronic Alerts in the Prevention of Anesthesia Awareness: the Michigan Awareness Control Study
Awareness during anesthesia is a problem receiving increased attention by patients, clinicians, and the general public. The incidence of intraoperative awareness has been reported to be between 1-2/1000 cases, but recent data…
- Trial name
- MACS (NCT00689091)
- Testing
- Bispectral Index Monitor, Electronic MAC alert
- Where
- United States
- Volunteers
- 22,185 people
- Sponsor
- University of Michigan
Pain
ADVANCE: Assessment for Defining Variability in Anesthesia Through Novel Clinical EEG
The present study is designed to compare prospectively whether sBIS, sEMG, or CVI variability (brain monitoring) can be used to predict unwanted intraoperative responses (high blood pressure, fast heart rate, tearing, etc.) to…
- Trial name
- CVI (NCT00689130)
- Where
- 4 sites in United States, Spain
- Volunteers
- 120 people
- Sponsor
- Medtronic - MITG
Anesthesia Brain Monitoring, Ketamine
Effect of Ketamine on BIS Values
Aim of this trial is to define if Concentration at the effector site (Ce) of Ketamine, calculated with DOMINO model infusion pump are correlated with Bispectral Index BIS values during general anaesthesia for breast surgery.
- Trial name
- NCT05288764
- Testing
- Bispectral Index
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- University of Padova