Clinical trials: Bladder
Endometriosis, Bladder Pain Syndrome
Translational Research in Pelvic Pain
This study aims to better understand the pathways leading to pain in women with two types of pelvic pain condition (endometriosis-associated pain and bladder pain syndrome) and determine whether these pathways can be used to…
- Conditions
- Endometriosis, Bladder Pain Syndrome, Chronic Pain
- Trial name
- TRiPP (NCT04001244)
- Where
- 2 sites in Portugal, United Kingdom
- Volunteers
- 787 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Neurogenic Bladder, Myelomeningocele
Can Dynamic Ultrasonography Replace Urodynamics in Follow-up of Patients With Myelomeningocele
Patients with neurogenic bladder need periodic evaluation with urodynamic study, a invasive and uncomfortable procedure. Aim: To evaluate the accuracy of dynamic ultrasonography as a feasible and noninvasive alternative…
- Trial name
- NCT03550898
- Testing
- Dynamic Ultrasonography
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Interstitial Cystitis
Effect of Interferential Electrical Stimulation on Pain Perception and Disability Level on Interstitial Cystitis
A total of 40 volunteers women with a diagnosis of interstitial cystitis. Their ages ranged from 25 to 40 years old; their body mass index was > 30 kg/m2 and were randomly assigned to a group (A) received interferential current…
- Trial name
- IF (NCT03844581)
- Testing
- interferential current, Propiverine Hydrochloride
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy Volunteers
A Study of APL-1501 Extended Release Capsules Compared to APL-1202 Immediate Release Tablets in Healthy Volunteers
The primary objective of the study is to assess safety and tolerability following administration of single doses of APL-1202 (immediate release) IR tablets and APL-1501 extended release (ER) capsules in healthy participants.
- Trial name
- NCT06435039
- Testing
- APL-1202, APL-1501
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Syneos Health
Colorectal Cancer, Pancreatic Adenocarcinoma
Circulating Tumor DNA Exposure in Peripheral Blood
This is a prospective, multi-center, blinded feasibility study. The objective of this study is to test the feasibility of the detection of tumor DNA of a variety of tumors in peripheral blood using a novel process for the…
- Conditions
- Colorectal Cancer, Pancreatic Adenocarcinoma, Gastric Cancer, Hepatocellular Carcinoma
- Trial name
- NCT03517332
- Where
- 6 sites in United States, Switzerland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Quantgene Inc.
Vesicoureteral Reflux
Determination of Voiding Patterns of Children With Vesicoureteral Reflux
Determine if the pattern of voiding differs in children with vesicoureteral reflux (VUR) compared to those who do not have VUR.
- Trial name
- NCT00186199
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stanford University
Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptom
A Prospective Comparative Study Evaluating the Safety and Efficacy of Transurethral Thulium Fiber Laser, Holmium Laser and Bipolar Enucleation of Large Sized Prostate
This study compares the safety and efficacy of three endoscopic enucleation techniques for large prostates (>100 mL) in patients with benign prostatic hyperplasia (BPH): Thulium Fiber Laser Enucleation (ThuFLEP), Holmium Laser…
- Conditions
- Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptom, Bladder Outlet Obstruction
- Trial name
- NCT07627178
- Testing
- Thulium Fiber Laser Enucleation of the Prostate (ThuFLEP), Holmium Laser Enucleation of the Prostate (HoLEP), Bipolar Transurethral Enucleation of the Prostate (B-TUEP)
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Bladder Cancer
Urine VOC Investigation in Bladder Cancer Diagnosis
The goal of this study to investigate the volatile organic compounds (VOCs) in the urine samples of both healthy individual and bladder cancer patients, using gas chromatography - mass spectrometry.
- Trial name
- NCT05671289
- Testing
- analysis of urine volatile organic compounds
- Where
- China
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Urinary Bladder Squamous Cell Carcinoma
Outcome of Radiation Therapy in Urinary Bladder Squampus Cell Carcinoma
Detection of distribution of clinico-pathological features of squamous cell carcinoma of urinary bladder and their relation to treatment outcome.
- Trial name
- NCT04815629
- Testing
- Radiotherapy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Bladder Cancer
Urinary Microbiome Differences in Bladder Cancer, Benign Urinary Diseases and Healthy Counterparts in Adult Male Population
The study aims to investigate alterations in the bladder microbiome in adult men with bladder cancer, healthy men, and men with benign urinary disease
- Trial name
- NCT06992986
- Testing
- Investigating differences in the bladder microbiome
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Regina Elena Cancer Institute
Interstitial Cystitis
The Efficacy of Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome
The purpose of this study is to evaluate efficacy of biomarker in patient with interstitial cystitis/painful bladder syndrome
- Trial name
- NCT01985880
- Where
- 2 sites in South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Overactive Bladder
Management of OAB in Female Patients .
The objective of this study is to compare the effectiveness of mirabegron, solifenacin, tadalafil (5mg), and their combination in relieving symptoms of overactive bladder (OAB) in a double-blinded prospective randomized…
- Trial name
- NCT06184334
- Testing
- Solfenacin, Mirabegron, Tadalafil 5mg
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elsayed Abdelhalim Elsayed
Transitional Cell Carcinoma of the Bladder
A Laser Detection for Bladder Cancer by (Photodynamic) Spectra of Urine
Research Problem: Bladder cancer is one of the major health concerns of the world. The present methods of diagnosis are: Ultra sound, Cystoscopy, CT scan and urine cytology.
- Trial name
- ALA (NCT02101931)
- Testing
- Amino levulinic Acid
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Princess Al-Johara Al-Ibrahim Cancer Research Center
Overactive Bladder With Symptoms of Frequency, Urgency, and Urge Urinary Incontinence
The Effect Of Fluconazole On Pharmacokinetics Of Fesoterodine In Healthy Subjects
This study is designed to estimate the effect of fluconazole (200 mg BID for 2 days), a moderate CYP3A4 inhibitor on the pharmacokinetics of a single 8 mg oral dose of fesoterodine in healthy adult subjects.
- Trial name
- NCT00911235
- Testing
- Fesoterodine, fesoterodine plus fluconazole
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer
Spinal Anesthesia, Nursing
The Effect of Local Dry Heat Applıcatıon and Half Shower on The Development of Urinary Retentıon and Paın
Urinary retention is defined as the inability to empty the bladder spontaneously even though the bladder is full. Although urinary retention is seen in two forms as acute and chronic, acute urinary retention is defined by the…
- Conditions
- Spinal Anesthesia, Nursing, Bladder Retention, Dry Heat Application
- Trial name
- NCT05580289
- Testing
- half-shower and hot pack
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Duzce University
Overactive Bladder Syndrome
Efficacy of Transcutaneous Versus Percutaneous Posterior Tibial Nerve Stimulation in the Overactive Bladder.
The main aim of this study, is compare the effectiveness of transcutaneous posterior tibial nerve stimulation versus percutaneous posterior nerve stimulation in patients with overactive bladder.
- Trial name
- NCT04483817
- Testing
- Transcutaneous tibial nerve stimulation, Percutaneous tibial nerve stimulation
- Where
- Spain
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Fisiocore LC,SL
Overactive Bladder, Urgency-frequency Syndrome
TEST-ON - Does iStim Reduce Urinary Urgency?
Overactive bladder (OAB) is a chronic disorder with an overall prevalence in the adult population of over 10%, but that may exceed 40% in elderly groups.
- Conditions
- Overactive Bladder, Urgency-frequency Syndrome, Urinary Frequency More Than Once at Night
- Trial name
- TEST-ON (NCT04957524)
- Testing
- iStim TENS unit and Transvaginal Probe
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Bladder
FILLing Protocols for the Right Bladder Volume at the RIGHT Time (FILLRIGHT)
The goal of this clinical trial is to compare evaluation of oral hydration protocols for the right optimal bladder filling prior to pelvic ultrasound.
- Trial name
- FILLRIGHT (NCT07642570)
- Testing
- Quantity A, Quantity B, Quantity C
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Bladder Cancer
A Phase I, Two-phase, Crossover Study to Evaluate the Safety, Tolerability and Pharmacokinetics of APL-1501 ER Tablets
A two-phase study design will be used for this pilot study. In the first phase, a 2×2 crossover study will be used to evaluate the safety, tolerability and PK characteristic of APL-1202 and APL-1501 ER Tablets 3.
- Trial name
- NCT04601766
- Testing
- APL-1202+APL-1501 ER Tablets 3+APL-1501 ER Tablets 2, APL-1501 ER Tablets 3+APL-1202+APL-1501 ER Tablets 2
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Asieris Pharmaceuticals (AUS) Pty Ltd.
Pelvic Organ Prolapse
Veritas Collagen Matrix Cystocele Repair Study - Postmarketing
The purpose of this study is to evaluate the Veritas Collagen Matrix in treating female patients with documented occurence of Pelvic Organ Prolapse as evidenced by a cystocele.
- Trial name
- NCT00860912
- Testing
- Collagen Matrix
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic