Clinical trials: Bladder
Urinary Incontinence
Translating Unique Learning for Incontinence Prevention
More than one in three US women suffers from the distressing, embarrassing, and often unreported problem of urinary incontinence (UI). UI severity increases with age and the financial cost exceeds $19 billion per year .
- Trial name
- TULIP (NCT01599715)
- Testing
- Instructional DVD, Bladder Health Class
- Where
- 2 sites in United States
- Volunteers
- 647 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Uterine Prolapse, Bladder Diseases
Pelvic Floor Muscle Training (PFMT) in Treatment and Prevention of POP (POP Study)
Background: The pelvic floor muscles (PFM) are located inside the pelvis, surrounding the urethra, vagina and rectum. They provide structural support for the pelvic organs.
- Conditions
- Uterine Prolapse, Bladder Diseases, Cystocele, Rectocele
- Trial name
- NCT00271297
- Testing
- Pelvic floor muscle training
- Where
- Norway
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Bladder Integrity, Bladder Function
Trendelenburg, Abdominal Insufflation and Time to Completion of Cystoscopy
Objective: The investigators seek to compare the efficiency of the cystoscopy with two interventions: 1. patient position during the cystoscopy (Trendelenburg (head down) or flat) 2.
- Conditions
- Bladder Integrity, Bladder Function, Ureteral Integrity, Ureteral Function
- Trial name
- NCT05786391
- Testing
- Flat position, Trendelenburg position, Insufflation
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Schistosoma Haematobium
Possible Diagnostic Protein Markers in Schistosoma Related Bladder Diseases.
Schistosomiasis is the second most common parasitic infection affecting humans, endemic in the Middle East, especially Egypt (1), and in 42 African countries (2). There are 5 main species infecting humans: S. mansoni, S.
- Trial name
- NCT05941884
- Testing
- Immunohistochemistry staining,, microscopic examination of urine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
Urinary Incontinence, UTI's
Bladder Environment: Microbiome Oxygen Relationship
The purpose of this study is to characterize bladder urinary oxygen tension (BUOT) in women whose urinary microbiomes contains at least one anaerobic bacterial species versus women whose urinary microbiomes do not contain…
- Trial name
- BEMOR (NCT02868463)
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Loyola University
Overactive Bladder
Evaluation of the TheraNova Neuromodulation System to Provide Durable Relief of Overactive Bladder Symptoms
To evaluate the safety and durability of the TheraNova Neuromodulation System in overactive bladder (OAB) patients.
- Trial name
- NCT05162833
- Testing
- TheraNova Neuromodulation Device
- Where
- 2 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Theranova, L.L.C.
Localized Renal Pelvis and Ureter Urothelial Carcinoma, Malignant Solid Neoplasm
Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer
This study collects and studies tissue and blood samples from patients with prostate or bladder/urothelial cancer that has recurred (come back) at or near the same place as the original (primary) tumor or has spread to other…
- Conditions
- Localized Renal Pelvis and Ureter Urothelial Carcinoma, Malignant Solid Neoplasm, Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Neoplasm in the Soft Tissues
- Trial name
- NCT01050504
- Testing
- Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Washington
Transcutaneous Electrical Nerve Stimulation, Urgent Urinary Incontinence
The Effectiveness of Parassacral Transcutaneous Stimulation Compared to Tibial Transcutaneous Stimulation, Home Protocol and Behavioral Therapy in the Treatment of Female Hyperative Bladder: Randomized Clinical Trial
Introduction: The overactive bladder is a highly prevalent condition, which negatively impacts the quality of life and daily activities of women.
- Conditions
- Transcutaneous Electrical Nerve Stimulation, Urgent Urinary Incontinence, Bladder Hyperactive, Women
- Trial name
- NCT04909047
- Testing
- parassacral transcutaneous electrostimulation
- Where
- 3 sites in Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centro de Atenção ao Assoalho Pélvico
Cystocele
Lower Urinary Tract Symptoms Screening Questionnaire
The purpose of this study is to determine the validity of a screening tool which has been designed to detect the presence or absence of lower urinary tract symptoms in the general female population.
- Trial name
- LUTS-2 (NCT01616810)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Recurrent Urinary Tract Infection
Recurrent Urinary Tract Infections and the Microbiome
The primary objective is to determine if polymerase chain reaction (PCR) (UTIP™) is more sensitive in identifying urinary tract infections (UTI's) than standard urine cultures.
- Trial name
- NCT04831840
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Miami
Enuresis, Nocturnal, Enuresis
MyPad - Intelligent Bladder Pre-void Alerting System
Development a 'dry alarm' that can help children and adolescents become dry at night.
- Trial name
- MyPad (NCT04280887)
- Testing
- MyPad
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Lancashire Teaching Hospitals NHS Foundation Trust
Sliding Sign, Vesicouterin Thickness
Vesico-uterin Thickness and Sliding Sign in Term Pregnancies
In this study, our aim was to evaluate the relationship of the bladder to the uterus including vesicouterin thickness and sliding sign in term pregnancies with at least one previous cesarean section and compare to controls.
- Conditions
- Sliding Sign, Vesicouterin Thickness, Term Pregnancy, Adhesion; Bladder
- Trial name
- sliding sign (NCT07523698)
- Testing
- ultrasound evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Adana City Training and Research Hospital
Prolapse Uterovaginal, Prolapse Bladder
Laparoscopic Central and Anterior Compartment Prolapse Surgery: A Meshless Sacrocolpopexy Technique
Mesh is widely applied in the abdominal approach to pelvic organ prolapse surgery, and sacrocolpopexy-sacrohysteropexy is the gold standard application, particularly for central compartment abnormalities.
- Conditions
- Prolapse Uterovaginal, Prolapse Bladder, Laparoscopy
- Trial name
- NCT05558852
- Testing
- Laparoscopic Meshless Sacrocolpopexy Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Cesarean Section Complications
Use Versus Non-use of Bladder Catheterization in Elective Cesarean Delivery
The goal of this randomized controlled trial is to investigate the impact of routine bladder catheterization in uncomplicated cesarean sections on time to ambulation, time to discharge, urinary retention, development of urinary…
- Trial name
- NCT06242756
- Testing
- Bladder catheterization
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Interstitial Cystitis/Painful Bladder Syndrome, Myofascial Pelvic Pain
Interstitial Cystitis: Elucidation of the Psychophysiologic and Autonomic Characteristics (ICEPAC) Study
Interstitial cystitis/painful bladder syndrome (IC/PBS) causes severe bladder pain and extensive disability in a large group of women int he prime of their productive lives.
- Trial name
- ICEPAC (NCT01616992)
- Testing
- Bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Urinary Bladder Trauma
Managment and Outcome of Urinary Bladder Trauma After Gynaecological and Obstetric Operations
We aimed to evaluate the management and outcome of bladder trauma after gynecological and obstetric operations at Assiut university hospital and to evaluate the methods of treatment of these complications.
- Trial name
- NCT06147804
- Testing
- Surgical managment of Urinary bladder trauma after gynaecological and obstetric operation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Urologic Diseases, Overactive Bladder Syndrome
Central Obesity in Cases of OAB
Obesity is not a homogeneous condition and that the regional distribution of adipose tissue is important to understanding the relation of obesity to disturbances in glucose and lipid metabolism.
- Conditions
- Urologic Diseases, Overactive Bladder Syndrome, Obesity, Abdominal
- Trial name
- NCT03750604
- Testing
- visceral fat obesity (surface area and function)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bladder Infections and Inflammations
Chronic Indwelling Foley and Catheter Associated Trauma (CIF-CAT) Study
To determine whether an indwelling low profile Kohli Atraumatic Catheter causes less macro-morphologic inflammation and edema to the bladder mucosa than a traditional indwelling Foley catheter as assess by computerized image…
- Trial name
- NCT03790826
- Testing
- cystoscopy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nellie Medical, LLC
Pain
Trial of an Oral Sucrose Solution Versus Placebo in Children 1 to 3 Months Old Needing Bladder Catheterization
INTRODUCTION AND JUSTIFICATION The use of sucrose has been well studied for certain procedures in neonatal intensive care unit patients and in the newborn nursery settings, particularly for venous blood draws, capillary blood…
- Trial name
- NCT01544985
- Testing
- 88% sucrose po solution
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Interstitial Cystitis/Painful Bladder Syndrome, Myofascial Pelvic Pain
Interstitial Cystitis: Examination of the Central Autonomic Network
This proposal aims to move the science of chronic pelvic pain (CPP) from simple associations towards an investigation of cause and effect relationships.
- Trial name
- ICECAN (NCT03008382)
- Testing
- Metoprolol Tartrate Oral Tablet, No intervention- observational sub-study
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University