Clinical trials: Blepharoplasty
Dermatochalasis, Ptosis, Eyelid
A Comparison of the Effect of Suture Material on Blepharoplasty Incision
The objective is to compare the effect of suture material on blepharoplasty incision. Outcomes of blepharoplasty scar and/or cosmesis will be compared between plain gut and polypropylene suture.
- Trial name
- NCT04585217
- Testing
- Randomized laterality of suture materials for closure (6-0 polypropylene monofilament suture vs fast absorbing gut suture on right eyelid)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Blepharoplasty
Evaluating Patient Reported Outcomes and Surgeon Satisfaction With Ziplyft™
The objective of this study is to evaluate patient-reported outcomes, surgeon reported outcomes, bruising, symmetry, the success of tissue adhesive for wound closure, and case time.
- Trial name
- NCT07144761
- Testing
- Ziplyft
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Osheru Inc.
Dry Eye Syndrome, Ptosis
The Effect of Eyelid Surgery on Dry Eye - a Prospective Study
The investigators aim to assess the effect of blepharoplasty with or without muller muscle resection on the symptoms of dry eye syndrome.
- Conditions
- Dry Eye Syndrome, Ptosis, Dermatochalasis
- Trial name
- NCT02376556
- Where
- Israel
- Volunteers
- 54 people
- Sponsor
- Sheba Medical Center
Lower Eyelid Steatoblepharon (Excess Eyelid Fat)
Phase 2 Study of XAF5 (XOPH5) Ointment for Reduction of Excess Eyelid Fat (Steatoblepharon)
This study will test whether XAF5 (XOPH5) ointment, applied once daily to the lower eyelids for 10 weeks, reduces the prominence of lower eyelid fat in adults with moderate to severe steatoblepharon (excess eyelid fat).
- Trial name
- NCT02230761
- Testing
- XOPH5 Ointment
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Topokine Therapeutics, Inc.
Eye Disorders
Dry Eye in Upper Eyelid Surgery: Muscle Versus Fat Removal
The aim of this study is to compare the effects of two different surgical techniques (Orbicularis Oculi excision and Orbicularis Oculi + Fat excision) applied in upper blepharoplasty surgery on dry eye and to evaluate the effects…
- Trial name
- NCT06985264
- Testing
- Upper Eyelid Blepharoplasty surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Mersin Training and Research Hospital
Scar Formation
The Effectiveness of Topical Silicone Application Combined With Photoprotection in the Development of Scarring Following Blepharoplasty
Assess the efficacy of utilizing topical silicone with photoprotection (Improscar Stick® 50) on the quality of healing following upper blepharoplasty, employing the Vancouver and POSAS scales (both patient and observer) over a…
- Trial name
- ETSACPDSFP (NCT07387536)
- Testing
- Silicone-based topical formulation with sunscreen (SPF 50) application
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Ptosis, Eyelid
Effect of Eyelid Patching After Ptosis Surgery
The goal of this randomized, controlled, observer-blinded study is to compare the effect of compression dressing after ptosis surgery.
- Trial name
- NCT05770973
- Testing
- Compression dressing (build by Kompressen, gauze swabs, Nobamed Paul Danz AG, Wetter, Germany and NOBALUMENAL® - steril, eye pad, Nobamed Paul Danz AG, Wetter, Germany
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Augenklinik LMU
Other Degenerative Disorders of Eyelid and Periocular Area
Botulinum Toxin to Improve Lower Blepharoplasty Scar
The combination of Botulinum toxin for crow feet (lateral part of orbicularis oculi muscle) and lower blaphaloplasty might have reduces the tension on the end of lower blaphaloplasty incision whereas the scar is more visible on…
- Trial name
- NCT02786550
- Testing
- Botulinum Toxin, Normal Saline
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Edema, Ecchymosis
Effects of Hyperbaric Oxygen Therapy on Surgical Wound Healing
The aim of this study is to test the effect of Hyperbaric Oxygen Therapy) HBOT (100% oxygen; 2.0 ATA; 90 minute total exposure) and compare against a hyperbaric sham treatment (HBST) (patient's breathing room air; 2.0 ATA; 90…
- Trial name
- BLEPH (NCT01605110)
- Testing
- Hyperbaric oxygen treatment
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Restorix Research Institute, LLLP
Anesthetics, Local, Blepharoplasty
Distraction Techniques in Periocular Anesthesia: Tapping vs Vibration
To compare the efficacy of topical tapping vs vibration in lowering pain scores for periocular anesthesia injections.
- Conditions
- Anesthetics, Local, Blepharoplasty, Age-Related Ptosis, Adult
- Trial name
- NCT06355817
- Testing
- Vibration, Tapping
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Manitoba
Aging
Age-Related Changes in Myosin Heavy Chain Composition in Human Orbicularis Oculi Muscle
Orbicularis oculi muscle is a key structure in the peri-orbital anatomy and is responsible for the major changes of aging in this area. Peri-orbital rejuvenation has been an issue of great interest in plastic surgery.
- Trial name
- NCT00154453
- Testing
- obtain surgical specimen for analysis
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Dermatochalasis of Eyelid
Effect of Compression Dressing After Upper Eyelid Blepharoplasty on Edema, Ecchymosis, Pain and Ocular Surface Irritation
Study to analyze whether there is a difference in postoperative outcome regarding edema, ecchymosis, pain, OSI and discomfort of the patients after blepharoplasty if a compression dressing is used or not.
- Trial name
- NCT06111170
- Testing
- Compression dressing
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Augenklinik LMU
Blepharoplasty, Upper Eyelid Blepharoplasty
Efficacy of Arnica D1 Ointment After Upper Blepharoplasty
Arnica ointment is currently used in homeopathic preparations for strains and bruises. In the field of plastic surgery, some surgeons advise patients undergoing blepharoplasty to use Arnica in order to prevent postoperative…
- Trial name
- ARINE (NCT01598909)
- Testing
- Arnica
- Where
- Netherlands
- Volunteers
- 136 people
- Sponsor
- Wynand BWH Melenhorst, MD
Blepharoptosis, Ecchymosis; Eyelid
Fibrin Sealant in Eyelid Surgery
This study is looking at the effect of Tisseel in eyelid surgery. Fibrin sealants (Tisseel) cause there to be less bleeding during surgery. Surgeons have used Tisseel for over two decades to reduce bruising.
- Trial name
- NCT05358977
- Testing
- Tisseel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Eyelid Diseases
Brassiere Brow Suture and Internal Browpexy
Brow ptosis is a common problem. internal browbexy and brassier suture are common surgical approach
- Trial name
- NCT04861454
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Benha University
Eyelid Diseases
Medial Fat Pad Preservation in Upper Eyelid Blepharoplasty
Medial upper eyelid pad of fat bulge is a common problem. medial fat pad preservation might be a good adjutant to upper eyelid blepharoplasty
- Trial name
- NCT05016362
- Testing
- medial fat preservation upper blepharoplasty
- Where
- United Arab Emirates
- Volunteers
- 50 people
- Sponsor
- Benha University
Dermatochalasis, Dermatochalasis of Eyelid
Comparison of Two Different Concentrations of Local Anesthetic in Patient Reported Pain in Oculoplastic Surgery
The goal of this clinical trial is to compare pain scores in people undergoing upper eyelid surgery. The main questions it aims to answer are: Is one concentration of local anesthetic (also called numbing or freezing injection)…
- Conditions
- Dermatochalasis, Dermatochalasis of Eyelid, Dermatochalasis of Both Upper Eyelids, Dermatochalasis of Both Eyes
- Trial name
- NCT06121141
- Testing
- Full strength lidocaine with epinephrine, Dilute lidocaine with epinephrine
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Timothy Ekhlassi
Dermatochalasis of Upper Eyelid
FACE-Q in Blepharoplasty
The aim of this study is to assess the effect of two different suturing techniques in patients undergoing bilateral upper eyelid blepharoplasty on the results of the FACE-Q Eye Module questionnaire for measuring patient-reported…
- Trial name
- NCT04924972
- Testing
- Blepharoplasty
- Where
- Austria
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Efficacy of a Technique (Brassiere Sutures)
TPS After Upper Blepharoplasty
Increased tarsal platform show (TPS) and decreased brow fat span (BFS) are associated with favorable results in women undergoing cosmetic blepharoplasty.
- Trial name
- NCT02879552
- Testing
- Traditional upper blepharoplasty, Brassiere suture with blepharoplasty
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Instituto de Olhos de Goiania
Post-operative Healing Following Blepharoplasty and Ptosis Repair
Efficacy of Loteprednol Ointment Following Eyelid Surgery
Inflammation occurs after any type of incisional surgery. This study will evaluate the efficacy of Loteprednol etabonate ointment vs. Soothe ointment (vehicle) for postoperative inflammation after routine eyelid surgery.
- Trial name
- NCT01749241
- Testing
- Loteprednol etabonate ophthalmic ointment, Vehicle Ophthalmic Ointment
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego