Clinical trials: Bloating
Gastrointestinal Disease, Flatulence
Evaluation of Gastrointestinal Symptoms Following Chilean Native Beans Consumption
The oligosaccharide content (raffinose, stachyose, and verbascose) in legumes would be responsible for gastrointestinal symptoms (bloating, pain, meteorism), associated with its consumption.
- Conditions
- Gastrointestinal Disease, Flatulence, Gastrointestinal Tolerance, Distension; Bowel
- Trial name
- NCT04243187
- Testing
- Chilean Native Beans
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Natalia Jara
IBS, Diarrhea Predominant, IBS, Constipation Predominant
Proposal Evaluating Time-specific Relationships Between Variables of Pain, Stress, and Bloating in IBS Diarrhea and Constipation Symptoms Using a Palm Pilot
Purpose: The associations between pain, stress, bloating, and their short interval temporal relationships to defecation in IBS D, C \& M are of great interest to the field of functional GI disorders, but have not been adequately…
- Conditions
- IBS, Diarrhea Predominant, IBS, Constipation Predominant, IBS, Mixed Symptoms
- Trial name
- NCT00619125
- Testing
- palm pilot recording responses to questionnaires
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Gas, Bloating
Assessment and Validation of Electronic Gas and Bloating Diary
The investigator's goal is to improve the patient's compliance and accurate capture of patient reported gas and bloating symptoms, by utilizing a phone application that interactively records each gas and bloating event in…
- Conditions
- Gas, Bloating, Distension, Constipation
- Trial name
- NCT04684849
- Testing
- APP Diary, Paper Diary
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Augusta University
Gastroparesis
GI Neuromuscular Pathology Prospective Registry
In this research study, biopsy samples will be collected to provide more insight into the underlying cause of the motility disorders, help direct further investigation into the cause of the underlying condition, provide future…
- Trial name
- NCT02165059
- Testing
- Surgical Full Thickness Biopsy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Indiana University
Chronic Constipation, Constipation
Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating
The purpose of this study is to evaluate the efficacy and safety of linaclotide compared with placebo in patients with chronic constipation (CC) and prominent abdominal bloating.
- Trial name
- NCT01642914
- Testing
- Linaclotide 290 micrograms, Linaclotide 145 micrograms
- Where
- 151 sites in United States, Canada
- Volunteers
- 487 people, healthy volunteers welcome
- Sponsor
- Forest Laboratories
Irritable Bowel Syndrome
Prevalence of Intestinal Parasitic Infections in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is common medical disorder and represent a group of diseases of the gastrointestinal tract that is characterized by chronic abdominal pain , bloating , passage of mucus or straining with bowel…
- Trial name
- NCT05830370
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Irritable Bowel Syndrome, Dyspepsia
Visible Abdominal Distension
Background. Abdominal distention is produced by an abnormal somatic postural tone. The authors developed an original biofeedback technique.
- Conditions
- Irritable Bowel Syndrome, Dyspepsia, Functional Bloating
- Trial name
- NCT06369753
- Testing
- Biofeedback
- Where
- 7 sites in United States, Canada and 5 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Gastrointestinal Health, Immune Health
Effect of Bacillus Subtilis BS50 Supplementation on Gastrointestinal Symptoms in Healthy Adults
The primary objective of this study is to investigate the effect of a novel Bacillus subtilis spore preparation on abdominal bloating, flatulence, and burping in healthy adults.
- Conditions
- Gastrointestinal Health, Immune Health, Cardiovascular Health, Digestive Health
- Trial name
- NCT05004454
- Testing
- Bacillus subtilis BS50 spore preparation, Maltodextrin
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- BIO-CAT Microbials, LLC
Irritable Bowel Syndrome, Dyspepsia
Treatment of Functional Abdominal Distension by Non-instrumental Biofeedback
Background. Abdominal distention is produced by an abnormal somatic postural tone. The authors developed an original biofeedback technique based on electromyography-guided control of abdominothoracic muscular activity.
- Conditions
- Irritable Bowel Syndrome, Dyspepsia, Functional Bloating
- Trial name
- NCT06150638
- Testing
- Biofeedback
- Where
- Spain
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Digestive Disease, Gut Health
Impact of B. Adolescentis iVS-1 Probiotic on Gastrointestinal Outcomes
The study team is conducting a consumer-driven, decentralized clinical research study to assess the impact of the consumer-grade probiotic supplement, iVS-1, on adults with moderate to severe gastrointestinal discomfort.
- Trial name
- NCT07408518
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Synbiotic Health
Constipation - Functional, Abdominal Pain (AP)
Co-Development and Validation of Colonic Symptom Pictograms for Young People
Severe constipation affects 10% of children, often leading to significant physical and emotional distress. While constipation is commonly associated with impaired bowel movements, it is fundamentally linked to abnormalities in…
- Conditions
- Constipation - Functional, Abdominal Pain (AP), Nausea and Vomitting, Bloating
- Trial name
- NCT07337343
- Testing
- Pictogram comprehension and validation
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Gastrointestinal Symptoms, Bloating
A Clinical Trial to Evaluate the Effects of Super Liver Liquid Drops on Gut Health, Digestive Comfort, and Daily Energy Levels
This is a decentralized (fully virtual), single-group, open-label, prospective clinical trial evaluating the effects of Super Liver Liquid Drops, a liquid botanical dietary supplement, on gut health, digestive comfort, energy…
- Conditions
- Gastrointestinal Symptoms, Bloating, Digestive Discomfort, Low Energy Levels
- Trial name
- NCT07742657
- Testing
- Super Liver
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- SuperBonsai Inc.
Healthy Subjects
Evaluation of the the Efficacy of a Digestive Health Supplement in Healthy Subjects
The objective of this study is to evaluate the efficacy of a digestive health supplement via waist circumference measurements, daily bowel habit and symptom logs, and self-perception questionnaires (SPQ) over 4 weeks.
- Trial name
- NCT06680219
- Testing
- Active comparator
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Bloating
Diaphragmatic Breathing for the Treatment of Bloating and Distension
The purpose of this study is to evaluate the efficacy of diaphragmatic breathing using the validated Mayo Bloating Questionnaire.
- Trial name
- NCT06596759
- Testing
- Diaphragmatic Breathing
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Gastrointestinal, Microbiota Balance
The Effects of a Postbiotic Supplement on Biomarkers of Gut Health
This study is a randomized, double-blind, two-arm, placebo-controlled trial of N=80 (40/arm) apparently healthy men and women between 18 and 65 years old to be recruited at a single investigational center in Northeast Ohio (i.e.…
- Conditions
- Gastrointestinal, Microbiota Balance, Microbiota, Cortisol
- Trial name
- NCT07527286
- Testing
- Postbiotic
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Verb Biotics LLC
Healthy
The Effect of Post Colonoscopy Abdominal Massage on Abdominal Pain, Distension, Discomfort and Patient Satisfaction
Background: Abdominal pain, distension, and discomfort are the most frequently seen side effects after colonoscopy. These side effects can cause physical and mental results and increased workloads and care costs.
- Trial name
- NCT04979351
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Recurrent Clostridium Difficile Infection, Laboratory Confirmed Clostridium Difficile Infection
Oral Vancomycin Followed by Fecal Transplant Versus Tapering Oral Vancomycin
Recurrent CDI is a growing problem with few treatment options that provide lasting effect. Fecal transplantation has been shown in several case series to be successful in controlling recurrent CDI.
- Trial name
- NCT01226992
- Testing
- Vancomycin, Fecal Transplant
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Stool Assessment, Skin Rash
GI Symptoms in Infants Fed Goat Milk-based Infant Formula
A cross-sectional observational survey was conducted in Brazil, Mexico, Russia, and The Netherlands by recruiting parents/legal guardians through social media.
- Conditions
- Stool Assessment, Skin Rash, Urticaria, Regurgitation
- Trial name
- NCT06755424
- Where
- Netherlands
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Dyspepsia, Epigastric Fullness
Effect of Gingest on Symptoms of Dyspepsia
This is a randomised, double-blind, placebo controlled study on the effect of Gingest (ginger root extract) on symptoms of dyspepsia in 150 participants with mild to moderate dyspepsia.
- Conditions
- Dyspepsia, Epigastric Fullness, Bloating, Epigastric Pain
- Trial name
- NCT03548363
- Testing
- Gingest powdered extract obtained from Ginger rhizomes
- Where
- Ireland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Atlantia Food Clinical Trials
Gut Health
Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms
The purpose of this study is the assess the effectiveness and safety of a Butyrate formulation and a Butyrate + Polyphenol formulation on gut health, permeability and associated symptoms
- Trial name
- NCT06419231
- Testing
- Butyrate Formulation, Butyrate + Polyphenol Formulation
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.