Clinical trials: Blood Circulation, open to volunteers
Diabetic Peripheral Neuropathy (DPN)
Ultrasound Assessment of Sciatic Nerve and Inferior Gluteal Artery in Diabetic Peripheral Neuropathy(DPN): Association With a Target Gene
Diabetic peripheral neuropathy (DPN) is a common and serious complication of diabetes that causes numbness, pain, and weakness, often starting in the feet.
- Trial name
- NCT07595887
- Testing
- No intervention (observational study)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Hospital of Shanxi Medical University
Total Hip Arthroplasty (THA)
Impact of Rehabilitation Therapy Using Strength and Blood Flow Restriction Training on Muscular Fitness and Regeneration After Elective Hip Replacement
In the present project, the framework conditions of outpatient rehabilitation at the Bonn Center for Outpatient Rehabilitation will now be used to prove whether sports science-controlled strength and BFR training has a similar…
- Trial name
- NCT07043127
- Testing
- BFR
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bonn
Parkinson Disease, Orthostatic Hypotension
Blood Pressure Effects on Cognition and Brain Blood Flow in PD
Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide. Besides causing symptoms that impair movement, PD also causes non-motor symptoms, such as problems thinking and orthostatic hypotension…
- Conditions
- Parkinson Disease, Orthostatic Hypotension, Dysautonomia
- Trial name
- NCT05400174
- Testing
- Tilt table (upright position)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Diego
Brain Blood Flow Impairment
Longitudinal Investigation of Brain Blood Flow Changes in Neurosurgical Patients
Primary study objective: Longitudinal observation of brain blood flow changes in neurosurgical patients with or without a neurosurgical intervention as compared to a healthy cohort.
- Trial name
- NCT04668261
- Testing
- Advanced imaging investigation
- Where
- Switzerland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Persistent Pulmonary Hypertension of Newborn
Treprostinil in Newborns With Pulmonary Hypertension; a Non-Interventional Study to Collect Data on Drug Utilization, Safety, and Effectiveness
This observational study will seek to describe the uses and safety and efficacy outcomes of treprostinil in clinical practice in patients with persistent pulmonary hypertension (PPHN).
- Trial name
- NEPHY (NCT06499363)
- Where
- 4 sites in France
- Volunteers
- 60 people
- Sponsor
- Ferrer Internacional S.A.
Cardiac Surgery, Extracorporeal Circulation; Complications
Evaluation of Blood and Cardiac Protein O-GlcNAcylation Levels in Cardiac Surgery in Children
Cardiac surgery requires the use of extracorporeal circulation (ECC). Age-related differences in inflammatory response, the greater susceptibility of immature organ systems to injury and the larger ratio of extracorporeal…
- Conditions
- Cardiac Surgery, Extracorporeal Circulation; Complications, Metabolism, Low Cardiac Output
- Trial name
- CardiOGlcNAc (NCT06754709)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Nantes University Hospital
Acute Ischemic Stroke
SUPERSTAR: Aspiration vs. Stent Retriever in Anterior Circulation LVO
This is a multicenter, open-label, blinded-endpoint, randomized controlled trial comparing super large bore catheter aspiration versus stent retriever thrombectomy as the first-line technique for anterior circulation large vessel…
- Trial name
- SUPERSTAR (NCT07555977)
- Testing
- Super Large Bore Catheter, Stent Retriever Thrombectomy
- Where
- China
- Volunteers
- 708 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Hospital Associated Disability, Immobility
Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.
This study investigates a new training method designed to help older adults preserve their muscle strength during hospitalization.
- Conditions
- Hospital Associated Disability, Immobility, Older Adults (65 Years and Older)
- Trial name
- GHOSTLY+ (NCT07294131)
- Testing
- Gamified isometric strength training with blood flow restriction, Standard Physiotherapy
- Where
- 3 sites in Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Stroke, Acute Ischemic
Trendelenburg Position for Acute Anterior Circulation Ischemic Stroke With Large Artery Atherosclerosis Etiology (HOPES 3)
The effect of head position as a nonpharmacological therapy on acute ischemic stroke (AIS) remains inconclusive. Recent HOPES2 (Head dOwn-Position for acutE moderate ischemic Stroke with large artery atherosclerosis) suggest the…
- Trial name
- NCT06010641
- Testing
- head-down position
- Where
- China
- Volunteers
- 600 people
- Sponsor
- General Hospital of Shenyang Military Region
Frailty Syndrome, Older Adults
Feasibility and Effects of Inspiratory Muscle Training Combined With Blood Flow Restriction for Frail Older Adults
This randomized controlled trial study aims to evaluate the feasibility and preliminary efficacy of a combined inspiratory muscle training (IMT) and blood flow restriction (BFR) intervention in frail older adults.
- Conditions
- Frailty Syndrome, Older Adults, Blood Flow Restriction (BFR) Training Effects, Inspiratory Muscle Training
- Trial name
- NCT07573995
- Testing
- Exercise
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University
Spinal Cord Injury, Cardio Vascular Disease
FES Cycling With BFR in the Spinal Cord Injury Population
Cardiometabolic Disease (CMD) is the silent killer within the spinal cord injury/disease (SCI/D) population. Many SCI/D patients' initial CMD presentation is with a heart attack, stroke, or sudden cardiac death, highlighting the…
- Conditions
- Spinal Cord Injury, Cardio Vascular Disease, Metabolic Diseases, Type 2 Diabetes, Cardiovascular Disease
- Trial name
- NCT07588503
- Testing
- Blood Flow Restriction, Functional Electrical Stimulated Cycling
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Dr. B. Catharine. Craven
Spinal Cord Injury
Effect of Blood Flow-restricted Exercise Frequency on Strength Recovery Following Incomplete SCI
The goal of this clinical trial is to determine the effect of treatment frequency on the physical recovery of adults with incomplete spinal cord injury.
- Trial name
- NCT07678437
- Testing
- Blood flow-restricted exercise
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Quality Living, Inc.
Thrombosis, Blood Coagulation Disorder
Dynamics of Platelet Activation in Patients With Ventricular Assist Device (VAD)
Consenting patients with end-stage heart failure that are implanted with/candidates for implant of a short-term/durable mechanical circulatory support device (e.g.: percutaneous microaxial pumps (Impella), extracorporeal membrane…
- Conditions
- Thrombosis, Blood Coagulation Disorder, Platelet Thrombus, Platelet Dysfunction Due to Aspirin
- Trial name
- PASVAD (NCT03255928)
- Testing
- PAS assay, TGT
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Scientific Institute San Raffaele
Supraspinatus Tendinitis
Anatomical Evaluation of Supraspinatus Through Ultrasonography and Biomechanical Measurements Following Blood Flow Restriction Therapy and Eccentric Exercise in Patients of Supraspinatus Tendinitis.
Patients of both gender groups with unilateral shoulder pain will be selected with age range 40-60 years from Sehat medical complex and randomly allocated into four groups (Group A, B, C and D) in Trial.
- Trial name
- NCT07873528
- Testing
- Blood flow restriction therapy, Eccentric Training, BFRT +ET
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sehat Medical Complex
Low Back Pain
Low Blood Flow Restriction Training on Low Back Pain
The aim of this randomized controlled trial is to find the effectiveness of low load blood restriction training on improving hamstring muscle strength, alleviating pain and reducing functional disability in nonspecific low back…
- Trial name
- NCT07576101
- Testing
- Conventional PT, Low Blood Flow Restriction Training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Ventilator Acquired Pneumonia, Central Line Associated Blood Stream Infections (CLABSI)
Evidence-Based Nursing to Reduce Adverse Events Regarding Ventilator Associated Pneumonia, Pressure Injuries and Central Line Bloodstream Infection in Intensive Care Unit in Bangladesh
Quality of care is crucial for preventing adverse events such as infection in the intensive care units (ICUs). The most common ICU-acquired infections include pneumonia such as Ventilator Associated Pneumonia (VAP), Pressure…
- Conditions
- Ventilator Acquired Pneumonia, Central Line Associated Blood Stream Infections (CLABSI), Pressure Ulcer (PU), Medical Device Related Pressure Ulcer (MDRPU)
- Trial name
- EBP in Nursing (NCT07299799)
- Testing
- Education with EBP, This is a pre- and post- quasi-experimental study.
- Where
- 2 sites in Bangladesh, Japan
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Single-ventricle, Congenital Heart Disease
Fontan Fitness Trial
The goal of this randomized control trial is to learn about physical fitness and exercise habits in children aged 10-17 with the Fontan Circulation through a home-based, digital exercise intervention.
- Trial name
- NCT06918795
- Testing
- Digital Exercise Intervention
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Philadelphia
Traumatic Brain Injury
Inhaled Nitric Oxide for Microvascular Dysfunction in Traumatic Brain Injury
Traumatic brain injury (TBI) causes acute deficits in cerebral perfusion which may lead to secondary injury and worse outcomes. Inhaled nitric oxide (iNO) is a vasodilator that increases cerebral blood flow and is clinically used…
- Trial name
- NCT05616910
- Testing
- inhaled nitric oxide
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Pennsylvania
Reliability, Ultrasound
Inter-Rater Reliability of Ultra Sound Based Rectus Abdominis Thickness Following Blood Flow Restriction Training
Accurate assessment of skeletal muscle morphology is important in sports physiotherapy, exercise rehabilitation, and research. B-mode ultrasonography is a non-invasive and accessible method for assessing muscle thickness…
- Trial name
- NCT07754162
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Sarcopenia, Chronic Stroke Patients
Effects of Blood Flow Restriction Training on Muscle Strength and Physical Function for Stroke-Related Sarcopenia
Effects of Blood Flow Restriction Walking on Muscle Strength and Physical Function in Chronic Stroke Patients with Sarcopenia: A Randomized, Sham-Controlled Trial Primary Objective: To evaluate the effects of BFR walking on…
- Trial name
- NCT06974461
- Testing
- Blood Flow Restriction (BFR) Walking
- Where
- 2 sites in Hong Kong
- Volunteers
- 64 people
- Sponsor
- The Hong Kong Polytechnic University