Clinical trials: Blood Donation
SARS-CoV-2 Vaccination
Adaptive Immune Response to COVID-19 Vaccination
AICOVI (Adaptive Immune Response to COVID-19 Vaccination) is a prospective clinical cohort study aiming at studying the kinetics of vaccine-specific antibody production after COVID-19 vaccination in health care workers.
- Trial name
- AICOVI (NCT04826770)
- Testing
- BNT162b2, AZD 1222, mRNA-1273
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Iron Deficiency
Neuroimaging of Donor Iron Deficient Study
This pilot study is designed to investigate (1) whether getting iron treatment affects iron in the brain and (2) how getting iron treatment affects brain functions when it is performing specific cognitive tasks.
- Trial name
- NCT02990559
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Columbia University
Blood Donors, Traumatic Blood Loss
Comparison of the Accuracy of Non-invasive Hemoglobin Measurement (SpHb) and Vena Cava Inferior Ultrasound
The aim of this work is determine the more successful noninvasive method by comparison of two noninvasive methods ( IVC ultrasound - noninvasive hemoglobin measurement (SpHb)) that used in the detection of patients with blood…
- Trial name
- NCT02944851
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Healthy Volunteer
Collection of Peripheral Blood Mononuclear Cells (PBMCs) From Healthy People for the Expansion of T Cells for Adoptive Cell Therapy
Title: Collection of Peripheral Blood Mononuclear Cells (PBMCs) from Healthy People for the Expansion of T Cells for Adoptive Cell Therapy Background: New therapies are being developed that use a person s own immune system to…
- Trial name
- NCT02821806
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Syncope, Vasovagal
Respiration and Applied Tension Strategies to Reduce Vasovagal Reactions to Blood Donation
For a number of years, researchers have examined the effects of the muscle-tensing technique, Applied Tension (AT), on blood donation-related vasovagal symptoms and donor retention.
- Trial name
- NCT03159156
- Testing
- Applied Tension, Respiration Control, Applied Tension/Respiration Control
- Where
- Canada
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- McGill University
Healthy, Blood Cell Count
Blood Testing at Entia
The investigators are recruiting healthy volunteers to donate 1-5 (depending on study visits. and donors will be notified upon invitation) finger prick blood samples or venous samples to Entia for the further development and…
- Trial name
- NCT05580055
- Testing
- Affinity
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Entia Ltd
Peripheral Blood Mononuclear Cell Donation
PBMC Donation in UCAR-T Cells
Peripheral blood mononuclear cell donation protocol for tumor immunotherapy study of UCAR-T cells
- Trial name
- NCT04091906
- Testing
- Peripheral blood mononuclear cell apheresis
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Blood Donors
Effect of a Web Page Based on a Motivational Video for Voluntary Blood Donation
Voluntary blood donation is currently a key issue in many countries, as the shortage of voluntary donors results in a deficit in the supplies of the Blood Banks of the hospitals.
- Trial name
- NCT04088695
- Testing
- Video through a web page, Informative text
- Where
- Peru
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
Blood Donation
Docudrama for Blood Donation in Ghana (DDID)
A cluster pilot RCT to evaluate the effectiveness of the docudrama compared to a control group (usual engagement with blood services) on repeat blood donation attempts among first-time blood donors.
- Trial name
- DDID (NCT07093307)
- Testing
- Docudrama, Control
- Where
- Ghana
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy Volunteers, Syphilis Serologic Assay Development
Blood Donation Study for ALPCO Syphilis-T and Syphilis-NT Assay Development
This prospective, single-center study will collect blood from approximately 50 adult volunteers aged 22 years or older. Participants will provide informed consent, complete an eligibility review, and undergo one blood draw of…
- Conditions
- Healthy Volunteers, Syphilis Serologic Assay Development, Blood Specimen Collection, Diagnostic Assay Development
- Trial name
- NCT07830550
- Testing
- ALPCO Syphilis-T, ALPCO Syphilis-NT CLIA Kits
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- American Laboratory Products Company
Healthy, Anemia
Noninvasive Hemoglobin Repeatability and Reproducibility in a Blood Donation Setting
The primary objective of this clinical investigation is to report on the repeatability and reproducibility of SpHb measurements from Rad-67 devices and DCI Mini sensors used to screen prospective blood donors at a donation center.
- Trial name
- NCT04490863
- Testing
- Rad-67 Pulse oximeter & DCI Mini sensor
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Atherosclerosis
Serial Phlebotomy in Voluntary Blood Donors
Blood donation has been proposed to be associated with reduced risk of cardiovascular disease, but the effects of phlebotomy on vascular function in human subjects have not been well characterized.
- Trial name
- NCT02762422
- Testing
- Phlebotomy
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Healthy
PCR-Based Detection of Bacterial Agents in Platelet Concentrates and Whole Blood
Using methods of molecular biology bacteria can be detected in blood. In comparison to conventional blood cultures "bacterial DNA" is isolated using a new sample preparation system in platelet apheresis concentrates and in the…
- Trial name
- NCT00482339
- Where
- Germany
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Jena
Iron Deficiency
Donor Iron Deficiency Study - Red Blood Cells From Iron-deficient Donors: Recovery and Storage Quality
Primary Hypothesis The 24-hour post-transfusion RBC recovery of units obtained from donors exhibiting iron-deficient erythropoiesis will not meet FDA standards for clinical use.
- Trial name
- DIDS (NCT02889133)
- Testing
- Iron-dextran, Saline, Blood Donation
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Columbia University
Blood Donation With Hemapheresis
Multinational Haemapheresis Vigilance Study
During a seven years period the participating transfusion medicine establishments will report all their non-trivial adverse events (AE) occurring during preparative hemaphereses.
- Trial name
- NCT01576237
- Testing
- blood donation
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- DGTI - Haemapheresis Vigilance Working Party
Alzheimer&Amp;#39;s Disease
Phosphorylated Tau Levels in Donated Blood
Alzheimer's disease (AD) is characterized by the accumulation of tau pathology, and blood-based biomarkers such as phosphorylated tau-217 (pTau217) have been identified as sensitive and specific predictors of AD risk.
- Trial name
- pTIDB (NCT07157839)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Blood Donation, Blood Transfusion
Donor Lifestyle and Nutritional Status, Blood Component Quality, and Patient Safety (ESENCIA)
The goal of this observational study is to evaluate how blood donors' lifestyle and nutritional status influence the quality of packed red blood cells (pRBCs) during storage and their impact on patient safety in transfused…
- Trial name
- ESENCIA (NCT07558369)
- Where
- Mexico
- Volunteers
- 1,014 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Perinatologia
Blood Donation
Sucrosomial Iron and Iron Sulphate to Blood Donors
2 different oral iron supplementations after blood donation are compared.
- Trial name
- NCT05678647
- Testing
- Sucrosomial Iron, Iron Sulfate
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Uppsala University Hospital
Iron Deficiency
Microbiome of Donor Iron Deficient Study
The goal of this pilot study is to test whether the microbiome is affected by intravenous iron repletion.
- Trial name
- NCT02990988
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Columbia University
Syncope, Vasovagal
Preventing Negative Reactions in First Time Blood Donors to Encourage Subsequent Blood Donations
Many individuals experience negative reactions when donating blood, including dizziness, lightheadedness, or fainting. Such reactions may discourage them from donating again.
- Trial name
- NCT00302900
- Testing
- Pre-Donation Water Consumption, Muscle Tensing Exercise During Donation, Muscle Tensing Exercise Prior to Donation
- Where
- 2 sites in United States
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Ohio University