Clinical trials: Blood Pressure, completed
Graves Disease, Graves Ophthalmopathy
Impact of Intravenous Methylprednisolone Treatment on Blood Pressure
Hypertension is common side effect of Cushing Syndrome (CS): in patients with endogenous CS and those treated with glucocorticosteroids (GCs). The impact of the intravenous GCs therapy on blood pressure (BP) remains unclear.
- Conditions
- Graves Disease, Graves Ophthalmopathy, Hypertension, Blood Pressure
- Trial name
- NCT03590080
- Testing
- Methylprednisolone
- Volunteers
- 32 people
- Sponsor
- Medical University of Warsaw
Intracerebral Hemorrhage, Stroke
The Second Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial
The purpose of this academic lead study is to determine if a treatment strategy of early intensive blood pressure (BP) lowering compared to conservative BP lowering policy in patients with elevated blood pressure within 6 hours…
- Conditions
- Intracerebral Hemorrhage, Stroke, Hypertension
- Trial name
- INTERACT2 (NCT00716079)
- Testing
- Blood pressure management policies
- Where
- 62 sites in United States, Argentina and 17 more
- Volunteers
- 2,839 people
- Sponsor
- The George Institute
Obesity, Abdominal, Dyslipidemias
Dietary Approaches for Cardiometabolic Health
This pilot study aims to recruit 30 adults with abdominal obesity, without major chronic disease, and test whether clinical dietary advice that is solely focused on the timing of eating (time restricted eating), has an effect on…
- Conditions
- Obesity, Abdominal, Dyslipidemias, Insulin Resistance, Blood Pressure
- Trial name
- DACH (NCT03527290)
- Testing
- Time Restricted Eating, Standard Cardiometabolic Health Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Hyperaldosteronism, Hypertension
Effects of Salt Intake on the Nervous Systems of Patients With Salt-Sensitive High Blood Pressure
Some patients with high blood pressure can experience an increase of blood pressure by 10 percent or more by taking in salt. These patients are referred to as having "salt-sensitive" (SS) hypertension.
- Trial name
- NCT00001176
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Healthy
L-NMMA Dose-response Study in Healthy Subjects
The purpose of this study is to investigate the effect of different levels of nitric oxide inhibition on blood pressure and arterial stiffness in healthy subjects.
- Trial name
- NCT01070940
- Testing
- NG-monomethyl-L-arginine (L-NMMA)
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Metabolic Syndrome
Korean Red Ginseng and Metabolic Syndrome
Five factor consisting of Metabolic syndrome is closely linked by insulin resistance. Until now, several studies have been performed about effects of Korea red ginseng on hypertension, diabetes, and hyperlipidemia, but not…
- Trial name
- NCT00976274
- Testing
- Korean red ginseng, starch
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- The Korean Society of Ginseng
Hypertension
Central Blood Pressure
The aim of the study is to check standard screening blood pressure in the arm and central blood pressure, the blood pressure at the heart in pregnant women.
- Trial name
- NCT03026010
- Testing
- central blood pressure
- Volunteers
- 100 people
- Sponsor
- St. Louis University
Hemodynamics, Arterial Pressure
Comparison of Mean Arterial Pressure After Endotracheal Intubation in Patients Undergoing Spine Surgery With Pre-emptive Nitroglycerine Versus Dexmedetomidine
This randomized controlled study compared nitroglycerine and dexmedetomidine for controlling blood pressure after insertion of a breathing tube in adults undergoing spine surgery under general anesthesia.
- Trial name
- NCT07901023
- Testing
- Nitroglycerin (NTG), Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Mayo Hospital Lahore
Blood Pressure, Arterial Line
Non Invasive Continuous Blood Pressure Sensor
The primary objective of this study is to collect training data in order to establish a method for correlating arterial blood pressure with voltage output signals from a non-invasive piezoelectric array sensor placed on the skin…
- Conditions
- Blood Pressure, Arterial Line, Anesthesia
- Trial name
- NCT05689294
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Ambulatory Blood Pressure Monitoring, Home Blood Pressure Monitoring
Novel BP Monitoring Methods to Study the Association Between Sleep BP Patterns and BP Values in Daily Life
Out-of-office blood pressure (BP) measurement by means of ambulatory BP monitoring (ABPM) or home BP monitoring (HBPM) is recommended for the diagnosis and management of hypertension in the latest guidelines.
- Conditions
- Ambulatory Blood Pressure Monitoring, Home Blood Pressure Monitoring, Blood Pressure Determination, Arterial Hypertension
- Trial name
- CABER-NET (NCT05781256)
- Where
- Italy
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Insomnia, Hypertension
Hypertension With Unsatisfactory Sleep Health
Insomnia and hypertension are common health problems that often occur together and influence each other. This practical, low-cost, clinical trial will evaluate two behavioral treatments for insomnia (a brief intervention with…
- Trial name
- HUSH (NCT02508129)
- Testing
- Brief Behavioral Treatment for Insomnia, Sleep Healthy Using the Internet, Enhanced Usual Care
- Where
- United States
- Volunteers
- 542 people
- Sponsor
- University of Pittsburgh
Blood Pressure, Hypertension
Launching a Salt Substitute to Reduce Blood Pressure at the Population Level in Peru
This protocol aims to implement, using a stepped wedge trial design, a population-level intervention to replace high-sodium salt for a salt substitute (low-sodium, high-potassium salt) to reduce blood pressure levels among adults…
- Trial name
- NCT01960972
- Testing
- Salt substitute
- Where
- Peru
- Volunteers
- 2,376 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
Obstructive Sleep Apnea, Hypertension
A Study to Assess the Efficacy and Safety of Lorundrostat in Participants With Obstructive Sleep Apnea and Hypertension
The primary purpose of the study is to assess the effect of lorundrostat taken orally (po) once a day on the Apnea-Hypopnea Index (AHI) in participants with moderate to severe obstructive sleep apnea (OSA) and hypertension.
- Trial name
- NCT06785454
- Testing
- Lorundrostat
- Where
- 27 sites in United States
- Volunteers
- 48 people
- Sponsor
- Mineralys Therapeutics Inc.
Hypertension
A Trial Comparing MICARDIS® (Telmisartan) and COZAAR® / LORZAAR® (Losartan) in Patients With Mild-to-Moderate Hypertension Using Ambulatory Blood Pressure Monitoring (ABPM)
The primary aim of the trial is to compare the influence of MICARDIS® (telmisartan) and COZAAR® / LORZAAR® (losartan) in lowering ambulatory diastolic blood pressure (DBP) during the last 6 hours of the 24-hour dosing interval as…
- Trial name
- TOPAS (NCT02200653)
- Testing
- High dose of MICARDIS®, once daily, Low dose of MICARDIS®, once daily, Low dose of COZAAR® / LORZAAR®, once daily
- Volunteers
- 387 people
- Sponsor
- Boehringer Ingelheim
Hypertension, Obstructive Sleep Apnea
Nocturnal Hypertension and Non-Dipping Blood Pressure
The purpose of this study is to determine if high salt diet contributes to high nighttime blood pressure. The investigators will determine if high compared to low salt diet increases 24-hour blood pressure levels.
- Trial name
- NCT03128177
- Testing
- Dietary sodium
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Alabama at Birmingham
Metabolic Syndrome
Green Coffee Extract and Metabolic Syndrome
Metabolic syndrome (Mets) is an assemblage of risk factors which can increase the risk of developing type 2 diabetes mellitus and cardiovascular disease.
- Trial name
- NCT02764957
- Testing
- green coffee extract
- Where
- Iran
- Volunteers
- 43 people
- Sponsor
- National Nutrition and Food Technology Institute
Cardiovascular Diseases, Heart Diseases
Blood Pressure Control in Juveniles - Longitudinal Study
To correlate dietary factors and changes in pressor substances, including aldosterone and norepinephrine, with blood pressure during growth and sexual development from childhood through adolescence.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00005181
- Sponsor
- Indiana University
Intracerebral Haemorrhage (ICH), Hypertension
Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial
An investigator initiated and conducted, multicentre, international, double-blinded, placebo-controlled, parallel-group, randomised controlled trial to determine the effect of more intensive blood pressure control provided by a…
- Trial name
- TRIDENT (NCT02699645)
- Testing
- telmisartan 20mg, amlodipine 2.5mg, and indapamide 1.25mg
- Where
- 58 sites in Australia, Brazil and 8 more
- Volunteers
- 1,671 people
- Sponsor
- The George Institute
High Blood Pressure
Intervention Study to Control High Blood Pressure for Korean American
The primary objective of the proposed clinical trials is to compare the differential reduction in blood pressure in underserved hypertensive adult Korean American.
- Trial name
- HBP (NCT00473681)
- Testing
- Self-Help Intervention Program-High Blood Pressure
- Where
- United States
- Volunteers
- 445 people
- Sponsor
- Johns Hopkins University
Hypertension
Dosing Study of the Effects of Nebivolol on Blood Pressure in Black Patients With Mild to Moderate Hypertension
The purpose of this study was to determine if nebivolol is superior to placebo for the treatment of elevated blood pressure in Black patients with mild to moderate hypertension.
- Trial name
- NCT00145236
- Testing
- Nebivolol
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Mylan Bertek Pharmaceuticals
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