Clinical trials: Blood Pressure Control
Cardiovascular Diseases, Blood Pressure Disorders
Effect of Korean Red Ginseng Extract on Blood Flow in Healthy Adults
The objectives of this clinical trial are to 1) determine the effect of the TP compared to placebo on blood flow and platelet aggregation, 2) to determine the effect of the TP on cardiovascular health compared to a placebo and 3)…
- Conditions
- Cardiovascular Diseases, Blood Pressure Disorders, Vasodilation, Platelet Aggregation
- Trial name
- NCT06236243
- Testing
- Korean Red Ginseng Extract Powder 120 mg/tablet, Korean Red Ginseng Extract Powder 500 mg/tablet
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Korea Ginseng Corporation
Cognitive Change, Affect
Cognitive and Blood Flow Effects of Mountain Tea
Two doses (475 mg and 950 mg) of Sideritis Scardica (SS or 'mountain tea') are investigated for cognitive, mood, blood pressure and cerebral blood flow effects in a healthy group of 50-70 yr olds, both acutely and following 28…
- Conditions
- Cognitive Change, Affect, Blood Pressure, Neuroimaging
- Trial name
- NCT03475823
- Testing
- Sideritis Scardica, Ginkgo biloba
- Where
- United Kingdom
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Hypertension, Obesity
Effectiveness of Avapro in Obese Normotensive/Hypertensive African Americans
The purpose of this study is to test the hypothesis that hypertension increases the anti-natriuretic effects of an angiotensin receptor antagonist during mental stress in overweight/obese African-American's who retain sodium…
- Conditions
- Hypertension, Obesity, Stress, Psychological, Blood Pressure
- Trial name
- Avapro3 (NCT02386293)
- Testing
- Irbesartan
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Augusta University
Healthy
Acute Effect of Nitrate From Natural Dietary Sources on Arterial Stiffness and Blood Pressures in Healthy Individuals
The purpose of this study is to evaluate the acute effect of a meal high in dietary nitrates on aortic augmentation index, brachial and aortic blood pressures, and subendocardial viability ration (SEVR).
- Trial name
- DNAB (NCT01604993)
- Testing
- Spinach soup, Asparagus soup
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06834893)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Nursing Student, Blood Pressure
Flipped Classroom Approach on Nursing Students' Blood Pressure
Effects of the Flipped Learning Model on Blood Pressure Knowledge and Self-directed Learning Skills of First-Year Nursing Students: A Randomized Controlled Study
- Conditions
- Nursing Student, Blood Pressure, Education
- Trial name
- NCT05337787
- Testing
- flipped classroom approach
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Hypertension
Measure the Effects of Specific Thoracic Chiropractic Adjustments on Blood Pressure and Pulse Rate
The purpose of this randomized controlled trial (RCT) is to measure the effects of specific thoracic (T5 to T1) chiropractic adjustments on BP and PR in a larger sample size of both normotensive and hypertensive humans.
- Trial name
- NCT01591967
- Testing
- Activator IV Adjusting Instrument
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Spinal Missions, Inc., LLC
Hypertension
Home Blood Pressure Telemonitoring and Case Management to Control Hypertension
In this project we develop and implement an intervention to improve hypertension control in a primary care setting that takes advantage of new technology (home blood pressure telemonitoring) and team models of care (pharmacist…
- Trial name
- Hyperlink (NCT00781365)
- Testing
- Telemonitors and pharmacy management
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Type 2 Diabetes
The Effects of Barberry Juice Consumption in Patients With Type 2 Diabetes
The aim of this study was to investigate the effect of barberry juice (BJ) as a natural antioxidant, on cardiovascular risk factors in patients with type 2 diabetes (T2DM).
- Trial name
- NCT03299153
- Testing
- barberry juice
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- National Nutrition and Food Technology Institute
Vascular Health
FLAVIOLA Health Study
Atherosclerosis progressively occurs with increasing age in the general population. So far most dietary intervention studies with flavanols were performed over short time frames and in small groups of young healthy and older…
- Trial name
- FHS (NCT01799005)
- Testing
- Flavanol (410 mg), Control (no flavanols)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Quality of Life, Health Promotion
A Randomized Control Trial of Conversations Advancing Resilience and Empowerment (CARE) Intervention
The investigators propose to implement and evaluate the effectiveness of the peer-led CARE Intervention designed to mitigate health differences among rural and low-income communities in Texas.
- Conditions
- Quality of Life, Health Promotion, Blood Pressure Monitoring, Self
- Trial name
- CARE (NCT07698964)
- Testing
- Conversations Advancing Resilience and Empowerment (CARE)
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Texas Rio Grande Valley
Elderly ; Moderate Risk Surgery
Optimized Anesthesia to Reduce Postoperative Cognitive Impairment in the Elderly
The aim of this study is to demonstrate that in elderly and frail patients, a narrower control of intraoperative blood pressure (BP) by the use of a continuous and noninvasive BP monitoring, coupled with an adequate depth of…
- Trial name
- NCT02698982
- Testing
- Depth of anesthesia monitoring (BIS, Covidien USA) and Continus non invasive blood pressure monitoring (Clearsight, Edwards LifeScience, USA), moderate risk surgery
- Where
- Belgium
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Healthy Female Subjects
Comparison of Pulse Wave and Blood Pressure Measurements Before, During and After Ergometry in Healthy Women
The objective of this randomized, controlled single blind study is to compare pulse wave and blood pressure measurements before, during and after exercise ergometry in healthy female subjects.
- Trial name
- NCT03792893
- Testing
- Ergometry H, Ergometry L
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Hypertension, Blood Pressure
Matão Controlling Hypertension (MatCH Study): Rationale and Design
Background Hypertension is the main risk factor for most cardiovascular diseases. Blood pressure (BP) control has been shown to reduce the incidence of stroke, myocardial infarction, renal diseases and heart failure.
- Trial name
- MatCH (NCT03147092)
- Testing
- Captopril 25Mg, Hydrochlorothiazide 25Mg Oral Tablet,, Atenolol, Losartan potassium 50mg
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Centro Neurológico de Pesquisa e Reabiitação, Brazil
Tachycardia, Hypertension
To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU.
The goal of this clinical trial is to to observe the haemodynamic parameters including Heart Rate Blood pressure Respiratory rate and Oxygen Saturation with or without giving reversal agent on extubation in patients receiving…
- Conditions
- Tachycardia, Hypertension, Hypoxia, Hyperventilation
- Trial name
- NCT07097441
- Testing
- neostigmine (reversal agent)
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Hypertension
A Controlled Study to Investigate the Effect of Multi-wave Light Emitting Diode (LED) Bed on Blood Pressure and Endothelial Function
The objective of this multi-center study is to investigate the effect of a multi-wave LED light bed on blood pressure and endothelial function in pre-hypertensive and mildly hypertensive adults.
- Trial name
- NCT04006158
- Testing
- LED bed
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- LED Intellectual Properties, LLC
Healthy
Study to Assess the Safety, Tolerability, and Pharmacokinetics of REGN5381 (an NPR1 Agonist) in Adult Humans
The primary objective of the study is to evaluate the safety and tolerability of single intravenous (IV) doses of REGN5381 in healthy normotensive and otherwise healthy hypertensive adults.
- Trial name
- NCT04506645
- Testing
- REGN5381
- Where
- 2 sites in Belgium
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Hypertension
Isometric Handgrip Exercise for Blood Pressure Management
The aim of this project is to conduct a randomised controlled trial to assess the effect of performing isometric exercise using a handgrip dynamometer on blood pressure.
- Trial name
- NCT02458456
- Testing
- Isometric resistance training
- Where
- Australia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of New England, Australia
Healthy
The Effect of Sodium Nitrite on Renal Function and Blood Pressure in Healthy Humans. A Dose-response Study
The purpose of this study is to investigate the effect of different doses of sodium nitrite infusion in 12 healthy subjects. The effects on renal handling of nitrite, nitrate, sodium and water, plasma concentrations of vasoactive…
- Trial name
- NCT02078908
- Testing
- Sodium nitrite, 40 micrograms/kg/hour, Sodium nitrite, 120 micrograms/kg/hour, Sodium nitrite, 240 micrograms/kg/hour
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Erling Bjerregaard Pedersen
Contraception
US Cycle Control and Blood Pressure Study
Birth Control Patch Study
- Trial name
- NCT00920985
- Testing
- Gestodene/EE (FC Patch Low, BAY86-5016), Oral contraceptive (equivalent to the active treatment tablets of Levlite), 21-day blister SH D00593A
- Where
- 28 sites in United States
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Bayer