Clinical trials: Blood Pressure Reduction
Elevated Blood Pressure, Endothelial Dysfunction
Effectiveness of Vitamin D Supplementation
This pilot study will examine the effectiveness of vitamin D supplementation on reducing blood pressure and improving endothelial function. Premenopausal African American women will be recruited.
- Trial name
- NCT02513823
- Testing
- 2,000 International Units (IU)of vitamin D3
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Reducing the Elevated Blood Pressure for Diabetic Hypertensive Patients
Metformin Versus Vildagliptin for Diabetic Hypertensive Patients
This is a controlled study to measure the efficacy of using metformin or vildagliptin for type 2 diabetic patients who suffers from hypertension to reduce cardiovascular risk resulting from both diabetes and hypertension using…
- Trial name
- NCT03253562
- Testing
- Metformin Pill, Vildagliptin 50 mg
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MTI University
Obesity, Overweight
Effect of Calcium/Vitamin D Supplementation on Body Weight and Fat Loss.
The aim of this study was to assess the effect of calcium/vitamin D supplementation (Caltrate 600 +D®) on body weight loss during a weight-reducing program
- Trial name
- NCT00353054
- Testing
- Caltrate® 600 + D, Weight loss intervention
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Laval University
Blood Pressure, Hypertension
Effect of a Multi-component Education Program on Salt Reduction in Adults
Excess salt intake is a major contributor to high blood pressure, the leading individual risk factor for cardiovascular events, such as stroke, myocardial infarction and heart failure.
- Trial name
- NCT03830021
- Testing
- Salt reduction program, Healthy lifestyle program
- Where
- 2 sites in Portugal
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- Academia Cuf Descobertas
Pain, Acute, Alloimmunisation in Pregnancy
Efficacy of Manuel Pressure and Local Cold Spray in Reducing Injection Pain in Pregnant Women
A randomized controlled study was planned to determine the effect of manual pressure and local cold spray application on the intensity of pain, fear, hemodynamic parameters, and satisfaction related to the pain reduction of human…
- Conditions
- Pain, Acute, Alloimmunisation in Pregnancy, Injection Site, Injection Fear
- Trial name
- NCT06231719
- Testing
- Cold Spray, Manuel Pressure, Standard Injection Procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Gulsum Coskun
Post-induction Hypotension
Evaluation of the Relation Between Patient Fasting Time and the Occurrence of PIH (Post Induction Hypotension)
This monocentre prospective trial aims to evaluate the relationship between fasting time and the occurence of PIH (post-induction hypotension).
- Trial name
- NCT07785635
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Ostrava
Hypertension
HARMONY Study (Hypertension Analysis of Stress Reduction Using Mindfulness Meditation and Yoga)
The purpose of this study is to determine if Mindfulness Based Stress Reduction (MBSR) is an effective intervention for lowering blood pressure in early unmedicated hypertensives.
- Trial name
- HARMONY (NCT00825526)
- Testing
- Mindfulness Based Stress Reduction (MBSR) Therapy
- Where
- 2 sites in Canada
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Weight Loss, Obesity
A Grapefruit Feeding Trial in Healthy, Overweight Adults
Folklore has suggested that consuming grapefruit may promote weight control. Sparse data exist to support this hypothesis, though there is some evidence of health promotional effects regarding blood pressure and lipid profiles.
- Conditions
- Weight Loss, Obesity, Cardiovascular Risk Factors
- Trial name
- NCT01452841
- Testing
- Grapefruit, Control
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Hypotension on Induction, Hypnotic Intoxication
Mean Arterial Pressure Reduction Anesthesia Induction Using Propofol Bolus or Tritiated Target-infusion
To compare haemodynamics and bispectral index values between conventional bolus propofol induction and target-controlled propofol infusion.
- Trial name
- NCT04291794
- Testing
- Propofol, Propofol Injection [Diprivan]
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brasilia University Hospital
Blood Pressure
Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure
The purpose of this study is to assess whether 480 mg/day magnesium glycinate supplementation for 12 weeks lowers blood pressure.
- Trial name
- NCT05690464
- Testing
- magnesium glycinate supplement
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hypertension
Flaxseed Lignan Supplementation in Elderly Participants With Stage I Hypertension
Current recommendations today suggest that use of therapeutic lifestyle changes, such as supplementation with specific dietary components and moderate exercise, are appropriate interventions for individuals with borderline high…
- Trial name
- NCT02391779
- Testing
- BeneFlax®, Walking training, Flexibility training
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Blood Pressure, Endothelial Dysfunction
Impact of Oranges on Cardiovascular Health
Cardiovascular disease (CVD) is the leading cause of deaths in the Western world. Established risk factors include high LDL cholesterol, high blood pressure and diabetes.
- Conditions
- Blood Pressure, Endothelial Dysfunction, Cardiovascular Disease Risk Reduction
- Trial name
- NCT01935362
- Testing
- Citrus supplement
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Menopause, Hypertension
Pituitary Derived-Intermedin is an Estrogen-Modulated Factor for Reducing Blood Pressure
Calcitonin, calcitonin gene-related peptides (CGRPs), adrenomedullin, and amylin belong to a unique group of peptide hormones important for the regulation of calcium balance, neurotransmission, cardiovascular homeostasis, and…
- Trial name
- NCT00133783
- Testing
- intermedin
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Hypertension
Stretching Versus Walking From Reducing Blood Pressure
High blood pressure is a leading risk factor for cardiovascular disease. Traditionally, one of the ways to treat or prevent high blood pressure is to prescribe aerobic exercise training (i.e.brisk walking).
- Trial name
- NCT03947996
- Testing
- Stretching exercise, Walking exercise
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Blood Pressure, Cardiovascular Diseases
Tibet Salt Reduction Study
1. Research background High blood pressure is one of the most important risk factors to cardiovascular diseases (CVDs). Reducing population blood pressure can control CVD incidence and lower mortality effectively.
- Conditions
- Blood Pressure, Cardiovascular Diseases, Death
- Trial name
- NCT02021435
- Testing
- salt substitute
- Where
- 2 sites in China
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Beijing Jishuitan Hospital
Decreased Vascular Flow
Optic Nerve Head Autoregulation During Changes in Arterial Blood Pressure
Constant despite changes in perfusion pressure. It is observed in many vascular beds of the human body to prevent that variations in perfusion pressure are directly transmitted into changes in blood flow.
- Trial name
- NCT01663883
- Testing
- Isometric exercise
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
High Blood Pressure
Stress Reduction and Hypertension Prevention in African Americans
There are major health disparities in Blacks associated with high blood pressure (BP) and psychosocial stress. We evaluated the effects of lifestyle modification with meditation in Black adults with high normal and normal blood…
- Trial name
- Milw2 (NCT04821505)
- Testing
- Health Education, Transcendental Meditation
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Maharishi International University
Blood Pressure, HDL Low
Effects of a 10 Component Dietary Supplement on Health and the Quality of Life
This open-label field trial evaluates the effects of treatment with a multi-pathway dietary supplement (Stem Cell 100+) that has been commercially available for several years.
- Conditions
- Blood Pressure, HDL Low, Stress, Lung Function Decreased
- Trial name
- NCT03052491
- Testing
- Stem Cell 100+
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Centagen, Inc.
Central Arterial Pressure
Effects of Heart Rate Reduction on Central Arterial Pressure in Healthy Individuals
The purpose of this project is to determine the effects of slowing heart rate upon both central and peripheral blood pressures using Ivabradine. The effects of Ivabradine will be compared to Metoprolol and placebo.
- Trial name
- NCT00825123
- Testing
- Ivabradine, Metoprolol
- Where
- Australia
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Hypertension
Examining Different Modes of Exercise for Acute Reduction in Blood Pressure
The purpose of the study is to compared different modes of exercise for eliciting post-exercise hypotension. The study will randomize 10 healthy participants to 30 minutes of either aerobic exercise, isometric exercise…
- Trial name
- NCT06628635
- Testing
- Exercise, Resting
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan