Clinical trials: Blood Sample
HPV Infection, Cervical Cancer
HPV-Based Screen-and-Treat Demonstration Project in Lilongwe
The purpose of this study is to assess completion and performance of the following novel invasive cervical cancer (ICC) screen-and-treat algorithm among 625 HIV-positive women in Lilongwe, Malawi: 1) rapid testing of…
- Conditions
- HPV Infection, Cervical Cancer, HIV Infections
- Trial name
- NCT04092257
- Testing
- VIA and thermocoagulation
- Where
- Malawi
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Healthy
Effects of a Hemp Seed-based Product on Appetite and Health Parameters
This study aims to develop a snack containing hemp seeds and to investigate the potential effects of its consumption on appetite parameters, body composition, and blood markers in healthy participants.
- Trial name
- NCT07917130
- Testing
- hempseed snack, control snack
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Halic University
Hepatitis B, Hepatitis C
Epidemiology of Hepatitis B, C and D and HIV Along the Maroni River Bordering French Guiana and Suriname (MaHeVi)
MaHeVi is a multicenter, cross-sectional, population-based study which will include 2500 adults in the health care centers / missions located on the 2 sides of the Maroni River.
- Conditions
- Hepatitis B, Hepatitis C, Hepatitis D, HIV Infections
- Trial name
- MaHeVi (NCT05002907)
- Testing
- Questionnaire, Biocollection, Delivery of results
- Where
- 2 sites in French Guiana, Suriname
- Volunteers
- 2,289 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Aortic Geometry, Vascular Remodeling
Impact of Aortic Geometry on Vascular Remodeling After Stent Implantation in Coarctation of the Aorta
This study aims to assess: 1. Aortic geometrical changes and their relationship to hypertension and cardiovascular events. 2. Aortic geometrical differences between healthy individuals and patients with repaired coarctation of…
- Conditions
- Aortic Geometry, Vascular Remodeling, Coarctation of Aorta, Blood Pressure
- Trial name
- NCT07131111
- Testing
- CT aortography, CMR
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemodynamics, Pain
Hemodynamic Effects of Different Vasoconstrictors in Mandibular Exodontia
Title of Study: The Effect of Different Vasoconstrictive Agents on Hemodynamics Among Patients Undergoing Simple Mandibular Exodontia: A Triple-Blind Randomized Controlled Trial Location: King Abdulaziz University Dental Hospital…
- Conditions
- Hemodynamics, Pain, ASA I-II Requiring Simple Dental Extraction of a Mandibular Tooth
- Trial name
- NCT07013071
- Testing
- 2% Mepivacaine with 1:100,000 epinephrine, 2% Mepivacaine with 1:55,000 Epinephrine Bitartrate
- Where
- Saudi Arabia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Diabetes Mellitus
Assessing Continuous Glucose Monitors in Healthy Children
Continuous glucose monitors may be useful in the treatment of children with Type 1 diabetes mellitus. The purpose of this study was to determine whether two FDA-approved continuous glucose monitors, the Continuous Glucose…
- Trial name
- NCT00069602
- Testing
- Continuous Glucose Monitoring System (CGMS), GlucoWatch G2TM Biographer (GW2B)
- Where
- 6 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jaeb Center for Health Research
HIV Infections
Quality of Life, Depression and Sexual Function in Men Living With HIV
This observational case-control study evaluates quality of life, depressive symptoms, and sexual function in heterosexual men living with HIV who are receiving effective combination antiretroviral therapy and have achieved…
- Trial name
- NCT07376239
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Type 2 Diabetes, Inflammation
Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids
Every 3 minutes a new case of diabetes is diagnosed in Canada, mostly type 2 diabetes (T2D) increasing the risk for heart disease.
- Conditions
- Type 2 Diabetes, Inflammation, Insulin Sensitivity/Resistance, Fatty Acids, Omega-3
- Trial name
- NCT04485871
- Testing
- Omega-3 fatty acids
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Institut de Recherches Cliniques de Montreal
Healthy Subjects, Pharmacokinetics
Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects
The purpose of this study is to evaluate the effect of steady state solifenacin and mirabegron on the pharmacokinetics of co-administered steady state digoxin.
- Conditions
- Healthy Subjects, Pharmacokinetics, Drug-Drug Interaction (DDI)
- Trial name
- NCT02127034
- Testing
- Mirabegron, Solifenacin, Digoxin
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
HIV Infections
A Crossover Adherence and Acceptability Study Assessing a DPP Capsule for HIV and Pregnancy Prevention
A randomized, crossover study to compare adherence, preference and acceptability of an over-encapsulated dual prevention pill (DPP capsule) containing oral pre-exposure prophylaxis (PrEP) and a combined oral contraceptive (COC)…
- Trial name
- NCT04778527
- Testing
- Dual Prevention Pill, PrEP tablet and a COC as two separate tablets
- Where
- South Africa
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Population Council
Anaphylaxis
Desensitization of Human Mast Cells: Mechanisms and Potential Utility for Preventing Anaphylaxis
This is an open-label, single-center study of whether oral penicillin desensitization of healthy sensitive subjects results in allergen cross-desensitization of mast cells by skin testing and desensitization of peripheral blood…
- Trial name
- NCT00868842
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Maintenance Dose, Osteocalcin
Estimation of a Maintaining Daily Jarlsberg Cheese-dose
The study objective is to estimate a maintaining daily dose of Jarlsberg cheese in healthy pre-menopausal women obtaining an increase in the osteocalcin level of at least 10% after 6 weeks on maximum efficacy dose (MED) of…
- Conditions
- Maintenance Dose, Osteocalcin, Vitamin K Deficiency
- Trial name
- NCT04188080
- Testing
- Jarlsberg Cheese
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Meddoc
Acute Coronary Syndrome, Angina Pectoris
Diagnostic Performance of Artificial Intelligence Algorithms in Prediction of Acute Coronary Syndrome Based on White Blood Cell Properties
The goal of this observational study is to evaluate whether artificial intelligence (AI) algorithms can predict or exclude acute coronary syndrome (ACS) in adults using data generated by routine hematology testing.
- Conditions
- Acute Coronary Syndrome, Angina Pectoris, NSTEMI - Non-ST Segment Elevation MI, STEMI - ST Elevation Myocardial Infarction
- Trial name
- NCT06384846
- Where
- Austria
- Volunteers
- 3,350 people, healthy volunteers welcome
- Sponsor
- RobotDreams GmbH
Healthy
Polyunsaturated Fatty Acids Supplementation and Blood Metabolome
Analysis of the effect of dietary intervention based on increased polyunsaturated fatty acid intake on health. Specifically changes in blood lipid profile, as well as proteomic and metabolomic profiles of healthy adults will be…
- Trial name
- NCT03892486
- Testing
- The high PUFA diet group
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Human Immunodeficiency Virus
Functionality of Male Condoms With a Silicone Elastomer Vaginal RIng
This trial will assess the potential impact of a vaginal ring on condom use by comparing the performance (total clinical failure, clinical slippage, and clinical breakage) of a standard male lubricated latex condom when the…
- Trial name
- NCT01755741
- Testing
- Condom
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Breast Cancer
Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer or BRCA Mutations
The purpose of this study is to learn more about the effects of your BRCA mutation on the ovaries. The BRCA gene can make it hard to conceive a child in the future. It may also bring on early menopause.
- Trial name
- NCT00823654
- Testing
- Blood draw and questionnaires
- Where
- 8 sites in United States
- Volunteers
- 609 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hepatitis C, Hepatitis B
Australian Hepatitis and Risk Survey in Prisons
The Australian Hepatitis and risk survey in prisons (AusHep) is a national prison-based blood-borne virus (BBV) surveillance study.
- Conditions
- Hepatitis C, Hepatitis B, HIV Infections
- Trial name
- AusHep (NCT05839522)
- Testing
- Point-of-care hepatitis C antibody test, Point-of-care hepatitis C RNA test, Point-of-care hepatitis B surface antibody test
- Where
- 24 sites in Australia
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Blood Pressure, Respiration
Verification Protocol for the Cloud DX Vitaliti Continuous Vital Signs Monitor (VERDICT-2)
The VERDICT-2 verification study will examine the accuracy of the Cloud DX Vitaliti Continuous Vital Signs Monitor (Model: CVSM-1A) in an ambulatory context with healthy participants.
- Conditions
- Blood Pressure, Respiration, Pulse Rate, Oxygen Saturation
- Trial name
- VERDICT-2 (NCT05886153)
- Testing
- Vitaliti Continuous Vital Sign Monitor Model CVSM-1A
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Obstructive Sleep Apnea
The Association Between Obstructive Sleep Apnea Severity and Red Blood Cells Indices
Obstructive sleep apnea syndrome (OSAS) is characterized by recurrent episodes of obstructive events (apnea and hypopnea) and intermittent hypoxia, which in turn contributes to the systemic inflammation that underlies this…
- Trial name
- NCT06265129
- Testing
- Complete blood picture (done in the morning after the night of monitored sleep by PSG. With stress on red blood cell indices (RBC count, MCV, MCH, RDW)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pulpitis - Irreversible, Pulpitis - Reversible
Observational Cross-sectional Study Aiming to Determine the Correlation Between Pulpal Status and IL-8 and Presepsin Levels in the Pulpal Blood.
Observational cross-sectional study aims to determine the correlation between pulpal status and IL-8 and Presepsin levels in the pulpal blood.
- Trial name
- Cross-section (NCT07466095)
- Testing
- IL-8 and Presepsin levels in the pulpal blood.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
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