Clinical trials: Blood Sample
Hepatocellular Carcinoma, Cholangiocarcinoma
Hepatobiliary Tumors Tissue Samples Acquisition
Hepatobiliary tumors have a poor prognosis and high individual heterogeneity, so it is of great significance to find important prognostic markers and then screen out specific subgroups of people; meanwhile, chronic hepatitis…
- Conditions
- Hepatocellular Carcinoma, Cholangiocarcinoma, Gallbladder Cancer, Biliary Tract Cancer
- Trial name
- NCT04445532
- Testing
- Gene expression analysis, Genomic analysis, Protein expression analysis
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Hemodynamic Instability
Role of Nebulized Dexmedetomidine in Blunting the Effects of Direct Laryngoscopy and Endotracheal Tube on Heart Rate and Blood Pressure.
The goal of this interventional study is to check the effectiveness of nebulized Dexmedetomidine in preventing the rise in blood pressure and heart rate in patients undergoing General Anesthesia.
- Trial name
- NCT06103721
- Testing
- Dexmedetomidine Injection [Precedex], Normal Saline
- Where
- Pakistan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Muhammad Haroon Anwar
HIV Infections, Sexually Transmitted Diseases
Increasing Engagement and Improving HIV Outcomes Via HealthMPowerment
The overall goal of this 3-arm randomized trial is to test whether a network-driven online intervention tailored for intersectional stigma amelioration can elicit online social support, promote intervention engagement, and…
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Stigma, Social
- Trial name
- NCT03678181
- Testing
- Information Resources, Social Support, HIV Testing
- Where
- 3 sites in United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Overweight
Effects of a Health-At-Every-Size Approach on Weight Management in Premenopausal Overweight Women
The purpose of this study is to measure the effects of a Health-At-Every-Size (HAES) approach on global health status of premenopausal overweight women preoccupied about their weight and who have been unsuccessful in previous…
- Trial name
- CHOIX (NCT01240499)
- Testing
- Health-At-Every-Size (HAES)
- Where
- Canada
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Laval University
Healthy
This Study in Healthy Volunteers Determines the Amount of BI 730460 in the Blood When Taken as Tablet. It Looks at How Different Doses of BI 730460 Are Taken up in the Body and How Well They Are Tolerated. The Study Also Tests How Food Influences the Amount of BI 730460 in the Blood.
The primary objective of the single-rising dose (SRD) part (trial part 1) is to investigate the safety and tolerability of BI 730460 in healthy subjects following oral administration of single rising doses.
- Trial name
- NCT03483077
- Testing
- BI 730460
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy, Blood Pressure
Capnogram and Fluid Responsiveness
Predicting fluid responsiveness in critically ill patients is of paramount importance. It can help define an adequate fluid balance.
- Trial name
- NCT03788707
- Testing
- Passive leg raising
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Augusta University
Neutropenia (Low White Blood Cell Count)
A Research Study To Test How Multiple Doses Of Filgrastim Hospira Works In The Body Of Healthy Study Subjects When Given by Subcutaneous Injection (SC) (Shot) Compared To An Already U.S.-Approved Drug Neupogen® (Amgen)
This is a study comparing two study drugs, Filgrastim Hospira and Neupogen®. Neupogen® is approved by the US Food and Drug Administration (FDA) to treat low numbers of specific kinds of white blood cells (WBC) known as…
- Trial name
- NCT02766634
- Testing
- Filgrastim Hospira (US), U.S.-approved Neupogen®
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pfizer
Hypovolemia
Study on Prediction of Fluid Responsiveness Using an Abdominal Compression-induced Change of Blood Pressure in Children
The purpose of this study is to evaluate predictability of an abdominal compression-induced change of blood pressure for fluid responsiveness in children.
- Trial name
- NCT02471534
- Testing
- abdominal compression
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
HIV Infections
Integrating PrEP Into Family Planning Services at Title X Clinics in the Southeastern US
Pre-exposure Prophylaxis (PrEP) is a daily pill to prevent HIV that, when taken as prescribed, reduces the risk of getting HIV from sexual intercourse or drug use.
- Trial name
- NCT04097834
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Blood Pressure
Evaluation of Continuous Non Invasive Blood Pressure With Adult Volunteers
A study to collect data recorded by devices for cNIBP evaluation purposes.
- Trial name
- NCT04876664
- Testing
- measuring blood pressure with noninvasive blood pressure device
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Chronic Hepatitis C
The Tolerability and Pharmacokinetics Study of HEC110114 Tablets in Healthy Adult Subjects
A Phase I, Single Center, Randomized, Double-blind, Placebo-controlled, Single \& Multiple Ascending Dose Study to Access the Tolerability and Pharmacokinetics of HEC110114 Tablets in Healthy Adult Subjects
- Trial name
- HEC110114 (NCT03903081)
- Testing
- HEC110114 tablet
- Where
- China
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
HIV/AIDS
Innovative Strategy to Offer Online Test and Treat for Thai MSM/TG
This study will ask Thai MSM and transgender women (TG) participants to self-select to participate in one of the 3 different study groups which provide various degrees of integrated online interventions and offline interventions…
- Trial name
- NCT03203265
- Testing
- Group A: Offline HTC, Group B1: Offline HIV testing and post-test counseling, Group B2: Online HIV testing and post-test counseling
- Where
- Thailand
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Healthy Individuals
Low Load, High Gains: Blood Flow Restriction's Impact on Quadriceps Adaptations
Low-load resistance exercise with blood flow restriction (BFR-RE) presents a compelling alternative to high-load resistance exercise (HL-RE), particularly in scenarios where high loads are not feasible due to various limitations.
- Trial name
- NCT06746792
- Testing
- Low-load resistance exercise with blood flow restriction, High-load resistance exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karabuk University
HIV Infections, Substance Use
Peer Behavioral Activation Utilization to Improve Substance Use and HIV Outcomes in People Receiving Long Acting Injectable-PrEP/ART (PUSH)
This randomized Type 1 hybrid effectiveness-implementation trial (N=186) will evaluate the effectiveness and implementation of a peer-delivered problem solving and behavioral activation intervention for adherence to LAI-PrEP/ART…
- Trial name
- PUSH (NCT06501781)
- Testing
- Peer Activate-LAI, Standard of Care HIV treatment or prevention with LAI-PrEP/ART
- Where
- 2 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Hypovolemic Shock, Hemorrhagic Shock
Sternal Intraosseous Transfusion of Autologous Whole Blood: A Comparison of Flow Rates and Degree of Hemolysis
In this study the impact of two CE marked and FDA approved sternal needles in comparison to intravenous access on the flow-rate of autologous reinfusion of whole blood and the possible hemolysis of red cells post-transfusion in a…
- Trial name
- NCT02924792
- Testing
- Reinfusion - Sternal IO needle, Reinfusion - Intravenous needle
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Healthy
X-Ray Computed Tomography and Blood Reactive Oxygen Species Level
The clinically widely used X-ray computed tomography examination has a low-grade radiation effect and recently has attracted much attention concerning the possible adverse effects of radiation on human body [ref. 1-5].
- Trial name
- NCT00712998
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Anesthesia, Cerebral Blood Flow
Hypertension and Cerebrovascular Hemodynamics in General Anaesthesia
During anesthesia, blood pressure-raising medications are often required to achieve an adequate blood pressure level. However, there is limited knowledge about what constitutes an adequate blood pressure to ensure sufficient…
- Conditions
- Anesthesia, Cerebral Blood Flow, Regional Cerebral Oxygen Saturation, Blood Pressure
- Trial name
- NCT06855407
- Testing
- Blood pressure elevation
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Umeå University
Performance Enhancing Product Use, Change, Body Weight
Effects of Acute Glycerol Ingestion on Performance, Metabolic and Biochemical Markers in International Athletes
This clinical study evaluates the acute effect of glycerol ingestion on performance (power output), weight, urine specific gravity, biochemical (antioxidants and lactate) and metabolic (indirect calorimetry) markers in…
- Conditions
- Performance Enhancing Product Use, Change, Body Weight, Change, Body Temperature, Antioxidative Stress
- Trial name
- NCT05295836
- Testing
- GLYCEROL
- Where
- Spain
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Blood Cancers, Blood Cancer
Rutgers University Study of the Genetics of Blood Cancers
The goal of this study is to enroll at least 10,000 participants nationally including affecteds and unaffecteds via online study portal, collect surveys online and a saliva sample through the mail, sequence DNA, and conduct…
- Conditions
- Blood Cancers, Blood Cancer, Leukemia, Lymphoma
- Trial name
- NCT07714044
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Diabetic Kidney Disease, Diabetes Mellitus, Type 2
Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathy
The study is focused on the possible improving effect of N-acetylcysteine on nephropathy of type-2 diabetic patients. Study design: Prospective clinical based study.
- Conditions
- Diabetic Kidney Disease, Diabetes Mellitus, Type 2, Diabetic Nephropathies
- Trial name
- (NAC) (NCT04531163)
- Testing
- N Acetylcysteine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
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