Clinical trials: Body Fat
Sperm Quality, Obesity
Obesity With Sperm Quality in Men With Fertility Need
This study aims to investigate the impact of different types of obesity on sperm quality. Participants will be divided into three groups: a normal BMI group, an obese group without pudendal fat wrapping the testicles, and an…
- Conditions
- Sperm Quality, Obesity, Sex Hormones, Visceral Fat
- Trial name
- NCT06353880
- Testing
- Participants will be categorized into three groups based on BMI and the presence of pudendal fat deposition.
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Yu xiaowei
Healthy
Multi-country Study- Effect of Dietary Fats on Fat Deposition
There is existing evidence to show that vegetable oils having unsaturated fatty acids in the sn-2 position with predominantly palmitic acid (C16:0) or stearic acid (C18:0) in the sn-1 and sn-3 positions of fat molecules do not…
- Trial name
- NCT02797483
- Testing
- Test Fat Blue, Test Fat Green, Test Fat Red
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Obese, Healthy
Investigating the Effect of Obesity on Eosinophil Recruitment in Human Adipose Tissue
Researchers are trying to better understand the relationship between inflammation in adipose tissue (AT) and insulin resistance.
- Trial name
- NCT04234295
- Testing
- Fat Tissue Biopsy
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Gingival Recession
Non-Pedicled Buccal Fat Pad Graft in the Treatment of Gingival Recessions
Background: This randomized controlled clinical study of split-mouth aimed to compare non-pedicled buccal fat pad graft (BFPG) with subepithelial connective tissue graft (SCTG) in the treatment of Miller Class I or II gingival…
- Trial name
- NCT02393053
- Testing
- Treatment with subepithelial connective tissue graft (SCTG), Treatment with non-pedicled buccal fat pad graft (BFPG)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Positivo
Alveolar Bone Loss, Atrophy
Buccal Fat Pad Derived Stem Cells With Cortical Tenting in Posterior Mandible Reconstruction
In this study the buccal fat pad derived stem cells (BFPSCs) is harvested from buccal fat pad tissue of the patients receiving posterior mandible augmentation.
- Trial name
- NCT02745366
- Testing
- BFPSC+FDBA+PRF, FDBA+PRF
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
HIV-infection
Physiologic Investigation of the Renin Angiotensin Aldosterone Axis in HIV
The purpose of this study is to see if individuals with HIV-infection, particularly those with increased belly fat, have abnormalities in the renin angiotensin aldosterone axis.
- Trial name
- NCT01407237
- Testing
- Angiotensin II Infusion
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obesity
Assessments of Adipogenesis, Lipid Turnover and Cellular Composition in Adipose Tissue in Response to Endurance Exercise
The purpose of this research study is to study the effects of endurance exercise training on adipose (fat) tissue quality and insulin sensitivity in men and women.
- Trial name
- ATLAS (NCT06602141)
- Testing
- Muscle Biopsy, Adipose Biopsy, Glucose Clamp
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Obesity, Diabetes Mellitus
Activating Brown Adipose Tissue Through Exercise
The energy burning capacity of brown adipose tissue makes it an attractive target for anti-obesity therapies. Sympathetic nervous system (SNS) is the classical regulator of brown adipose tissue; however, recent findings show a…
- Conditions
- Obesity, Diabetes Mellitus, Metabolic Syndrome X
- Trial name
- ACTIBATE (NCT02365129)
- Testing
- Exercise training based on recommendations for adults (WHO)
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Hyperlipidemia
Effect of Cheese on Cardiovascular Risk
The main objective of the current study is to examine whether a high intake of regular-fat cheeses (Danbo and Cheddar) affect blood lipids differently than an isocaloric intake of either other fatty animal food products or of…
- Trial name
- ECCA (NCT01739153)
- Testing
- Dietary intervention: CHEESE (High cheese intake), Dietary intervention: MEAT (High Meat intake), Dietary intervention: CARB (High Carbohydrate intake)
- Where
- Denmark
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Hypovitaminosis D, Insulin Resistance
Hypovitaminosis D : A Link Between Bone/Mineral and Fat/Fuel Metabolism
The optimal dose of vitamin D needed to optimize beneficial effects on musculoskeletal outcomes remains to be defined. Equally unclear is the impact of vitamin D on fuel metabolism and insulin sensitivity in human subjects.
- Conditions
- Hypovitaminosis D, Insulin Resistance, Obesity, Osteoporosis
- Trial name
- GEHF-VitD (NCT01315366)
- Testing
- Euro D and Ci-CalD, Euro D, Ci-CalD
- Where
- Lebanon
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Cardiometabolic Health
The InterSat Study
In response to the removal of trans fats from our foods, the food industry now uses interesterified (IE) fats. Randomly interesterified (IE) fats rich in palmitic (Europe) and stearic (North America) acids are the most commonly…
- Trial name
- InterSat (NCT04418102)
- Testing
- Palmitic acid rich interesterified fat, Stearic acid rich interesterified fat
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- King's College London
To Evaluate the Effect of Pioglitazone on Glucose Metabolism of Fat Tissue by Using FDG-PET/CT Imaging
Pioglitazone Decreases Visceral Fat Metabolism
Excess visceral fat is associated with chronic systemic inflammation and cardiovascular complications. Pioglitazone has been reported to variably influence visceral fat volume, but it its effect on metabolic activity of the…
- Trial name
- NCT01819402
- Testing
- Pioglitazone vs Glimepiride
- Where
- Japan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kurume University
Cognitive Performance, Gaming Performance
Citicoline Dose on Energy Drink Efficacy
The purpose of this study is to determine how the doses of cognitive-enhancing ingredients such as citicoline and caffeine effect the efficacy of acute energy drink consumption for improving cognitive performance (primary…
- Conditions
- Cognitive Performance, Gaming Performance, Blood Pressure, Heart Rate
- Trial name
- NCT06890962
- Testing
- Energy drink consumption
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Nathaniel Jenkins
Osteoporosis, Postmenopausal
MRI Study of the Distal Radius Bone Marrow Fat Fraction in Osteoporotic and Healthy Women
The aim of the study is to test whether the distal radius bone marrow show significant difference in the fat fraction in young women compared to post menopausal women with and without osteoporosis.
- Trial name
- NCT03742362
- Testing
- MRI scans of distal radius
- Where
- Israel
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Uri Nevo
Obesity
Nighttime Protein Intake on Overnight Lipolysis and Morning Fat Oxidation in Obese Men
Single macronutrients will be consumed before sleep by obese men. Overnight lipolysis will be measured with the microdialysis technique by measuring glycerol concentration and blood flow in abdominal adipose tissue.
- Trial name
- NCT02211391
- Testing
- Casein Protein
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Florida State University
Type 2 Diabetes Mellitus, Nonalcoholic Fatty Liver Disease
Effect of Empagliflozin on Liver Fat in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
This prospective, open-label, randomized clinical study will evaluate the effect of empagliflozin 10 mg daily, added to standard T2DM treatment, on liver fat and hepatic parameters in adults with type 2 diabetes and nonalcoholic…
- Trial name
- EMPA-LIVER (NCT07915596)
- Testing
- Empagliflozin 10/15 mg administered orally once daily in addition to standard treatment for type 2 diabetes mellitus.
- Where
- Bangladesh
- Volunteers
- 792 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Obesity
Insulin Regulation of Lipolysis and Lipolysis Proteins
These studies will define the abnormalities in the adipocyte proteins that are involved in the failure of insulin to suppress lipolysis normally in humans with upper body obesity and will help discover the mechanism by which…
- Trial name
- NCT03866408
- Testing
- Immediate weight loss, Pioglitazone, Deferred weight loss
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity
Microvascular Flow Assessment Repeatability Study: The MARS Study
The purpose of this study is to test a method of imaging (taking a picture) of the abdomen (belly), neck, thigh and calf (lower leg) areas of the body, using ultrasound along with a drug which makes the pictures look clearer.
- Trial name
- MARS (NCT01242020)
- Testing
- Perflutren Lipid Microsphere Injectable Suspension
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Overweight, Obesity
Effects of Red Beetroot Juice on High-Fat Meal-Induced Endothelial Dysfunction and Cardiometabolic Disturbances
Aside from aging, numerous factors increase the risk for developing cardiovascular disease (CVD) including diet and nutrition. High-fat meal consumption induces postprandial vascular endothelial dysfunction and other…
- Conditions
- Overweight, Obesity, Aging, Menopause
- Trial name
- NCT02949115
- Testing
- 70 mL red beetroot juice, 70 mL red beetroot juice without nitrate
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Knee Osteoarthritis, Elasticity Imaging Techniques
Elasticity of the Hoffa's Fat Pad in Patients With Knee Osteoarthritis
Knee osteoarthritis (OA) is a common problem in clinical settings. Knee OA is well known for its association with the wear and tear of the cartilage and osteophyte formation.
- Trial name
- NCT05439317
- Where
- Taiwan
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
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