Clinical trials: Body Weight Control
Overweight and Obesity
Effect of Post-exercise Nutrition on Glycemia in Women
The purpose of this study is to assess whether post-exercise Greek yogurt following a single session of aerobic exercise improves metabolic and musculoskeletal health in women with overweight/obesity.
- Trial name
- PEN (NCT05876260)
- Testing
- Greek yogurt, Carbohydrate-based study supplement, Exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Endotoxemia, Intestinal Microbiota
Dietary Intervention to Reduce Metabolic Endotoxemia
The goal of this randomized clinical trial is to compare an antiinflammatory and environmentally friendly dietary strategy (AIA-D) designed based on the planetary health diet recommendations translated to the regional context and…
- Conditions
- Endotoxemia, Intestinal Microbiota, Dietary Habits, Clinical Trial
- Trial name
- NCT05776329
- Testing
- AIA-D, CONV-D
- Where
- 2 sites in Mexico
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Centro de Investigación en Alimentación y Desarrollo A.C.
Overweight or Obesity
A Study to Evaluate Features of KN069 in Participants With Obesity or Overweight
This is a Phase 1, First-in-human, double-blinded, placebo-controlled study which aims to investigate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and the immunogenicity of KN069 in Chinese male…
- Trial name
- NCT06547775
- Testing
- KN069
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Suzhou Alphamab Co., Ltd.
Insulin Sensitivity, Obesity
The Metabolic Effects of Cynara Supplementation in Overweight and Obese Class I Subjects With Newly Detected Impaired Fasting Glycaemia.
Impaired fasting glucose (IFG) is a condition that precedes diabetes and increases the risk of developing it. Studies support the hypoglycemic effect of Cynara cardunculus (Cs) extracts due to the content of chlorogenic acid…
- Conditions
- Insulin Sensitivity, Obesity, Overweight
- Trial name
- NCT04616404
- Testing
- 500 mg of artichoke extract
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Obesity
Randomized Controlled Clinical Trial of Weight Loss Programs in Obese Persons
The purpose of this study is to compare two approaches to a diet and exercise-based weight loss program.
- Trial name
- SHINE (NCT00960414)
- Testing
- SHINE
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Body Weight
Pulse Biomarker Discovery
Dietary pulses, including beans, chickpeas, and lentils, are high in soluble fiber with potential benefits to human health: Pulses are moderate energy density foods, low in fat and high in dietary protein, fiber, vitamins and…
- Trial name
- NCT04887584
- Testing
- Control diet, Low Pulse diet, High Pulse diet
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Obesity, Pregnancy
A Clinical Care Pathway for Obese Pregnant Women: A Pilot Cluster RCT
Clinics will be randomized to the use of the care pathway for obese pregnant women or standard care. Women who are (1) up to 20 weeks + 6 days gestation into their pregnancy, (2) are carrying one baby (not twins) that is healthy…
- Trial name
- NCT02534051
- Testing
- Clinical Care Pathway
- Where
- Canada
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- McMaster University
Obesity, Childhood
A Trial of Two Family-based Childhood Obesity Treatment Programs
The primary aim is to determine the relative effectiveness in child BMI z-scores at 3, 6, and 12-months post baseline of iChoose+ versus Family Connections.
- Trial name
- NCT03245775
- Testing
- iChoose, Family Connections
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Pharmacology, Clinical
Study on the Safety of Neladenoson Bialanate, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Dug Given as a Single Oral Dose in Participants With Liver Impairment and Healthy Participants Matched for Age-, Gender-, and Weight
Neladenoson bialanate is currently under clinical development for a condition in which the heart has trouble pumping blood through the body (chronic heart failure).
- Trial name
- NCT04322253
- Testing
- Neladenoson bialanate (BAY 1067197)
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Bayer
Lifestyle Risk Reduction, Nutrition Poor
Culturally Appropriate Nutrition Communication for Mexican American Women
A randomized controlled trial to test the effects of culturally appropriate nutrition communication for Mexican American women.
- Conditions
- Lifestyle Risk Reduction, Nutrition Poor, Chronic Disease, Obesity
- Trial name
- NCT04352530
- Testing
- Health Communication
- Where
- United States
- Volunteers
- 881 people, healthy volunteers welcome
- Sponsor
- University of California, Merced
Worsening Chronic Heart Failure, Chronic Kidney Disease
A Study to Learn How BAY94-8862 Moves Into, Through and Out of the Body, How Safe it is and How it Affects the Body in Adult Participants With Reduced Kidney Function and in Healthy Participants With Similar Age, Weight and Gender Distribution
Researchers are looking for a better way to treat people who have worsening of chronic heart failure, a long-term condition where the heart does not pump blood as well as it should.
- Trial name
- NCT04908436
- Testing
- Finerenone (BAY94-8862)
- Where
- Germany
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bayer
Glucagon-like Peptide-1, Smoking Cessation
Smoking Cessation Facilitated by Glucagon-like Peptide-1 (GLP-1) Analogues
Cigarette smoking is the leading preventable cause of premature death worldwide. However smoking is a very difficult addiction to break whereby main reasons for not quitting or relapsing after cessation are the nicotine…
- Conditions
- Glucagon-like Peptide-1, Smoking Cessation, Weight Change, Body, Craving
- Trial name
- SKIP (NCT03204396)
- Testing
- Dulaglutide, 0.5 ml normal saline (0.9% sodium chloride [0.9% NaCl])
- Where
- Switzerland
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Obesity
Small Changes a One Year Protocol for Weight Management
A trial comparing Treatment as usual with Motivational Interviewing focussed treatment in the 'Small Changes' programme.
- Trial name
- NCT02453854
- Testing
- Group motivational interviewing
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Small Changes
Pediatric Obesity
Efficacy of a School-based Obesity Prevention Program in Mexican Schoolchildren: Cluster Randomized Controlled Trial
There is evidence that obesity prevention programs show positive effects on obesity and lifestyle parameters. However, the effect of the programs delivered by different implementers is unknown, and in Mexico, the available…
- Trial name
- NCT05461703
- Testing
- Planet Nutrition Program
- Where
- Mexico
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Universidad de Sonora
Obesity
One-anastomosis Gastric Bypass/Mini-Gastric Bypass Versus Roux-en Y Gastric Bypass
The aim of this prospective randomized controlled trial is to compare the two procedures One-anastomosis gastric Bypass/Mini-gastric Bypass (OAGB/MGB) and Roux-en Y gastric bypass (RYGB) in relation to intraoperative and…
- Trial name
- MGBvsRYGB (NCT03045679)
- Testing
- RYGB, OAGB/MGB
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sana Klinikum Offenbach
Overweight, Elevated Cholesterol
Observational Study of Lyzme5 Impact on Cholesterol and Body Weight in Man
This observational placebo-controlled pilot study is intended to document whether or not Lyzme5, an over-the-counter (OTC) proprietary nutritional supplement product can positively impact, (a) weight and, (b) cholesterol levels…
- Trial name
- Lyzme5 (NCT01634646)
- Testing
- Lyzme5
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Jeff Golini
Obesity, Weight Loss
A Multidisciplinary Weight Loss Program at AUB-MC
The current project aims at evaluating the feasibility and efficacy of a multi-disciplinary weight loss program, using an innovative and simple dietary intervention at the American University of Beirut Medical Center (AUB-MC).
- Trial name
- NCT04194424
- Testing
- Multidisciplinary weight loss program, Standard Care, Metformin Hcl 850Mg Tab
- Where
- Lebanon
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Weight Management, Obesity Prevention
Advancing Biopsychosocial Care Training Initiative
This project will compare two training approaches for US Preventive Services Task Force recommended obesity care in Federally Qualified Health Centers (FQHC) across four aims.
- Conditions
- Weight Management, Obesity Prevention, Obesity and Obesity-related Medical Conditions, Obesity and Overweight
- Trial name
- ABC Initiative (NCT07049861)
- Testing
- Comprehensive Multidisciplinary Obesity Care, Implementation as Usual Control
- Where
- United States
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Overweight and Obesity, Body Weight Changes
FatMax Training on Metabolic and Epigenetic Parameters
Exercise is an essential pillar for the health of all individuals, as it contributes to physical, mental, and emotional well-being.
- Trial name
- NCT06553482
- Testing
- FatMAx training intervention, FatMax and physical endurance exercise intervention, Control
- Where
- Mexico
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Stress, Obesity
Decreasing Stress and Improving Self-control With "Stress in Control" (Sync) Training
This is a study of treatment approaches aimed to improve self-control and decrease stress and unhealthy/maladaptive behaviors such as drinking, overeating, and smoking.
- Conditions
- Stress, Obesity, Overeating
- Trial name
- Sync (NCT01721499)
- Testing
- Nutritional Counseling, Mindfulness Intervention
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Yale University
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