Clinical trials: Body Weight Control
Obesity
The Symbiont-Restore Study
Within the framework of the Science Foundation Ireland funded Microbe Restore Project, the Symbiont Restore Study is an Investigator-initiated trial which explores the prospective health advantages associated with a particular…
- Trial name
- NCT05942586
- Testing
- Probiotic capsule (L. reuteri PB-W1™), Prebiotic sachet (Prebiotic Blend)
- Where
- Ireland
- Volunteers
- 137 people
- Sponsor
- University College Cork
Obesity
The Use of the Internet to Facilitate Weight Loss and Maintenance.
This project is assessing the effectiveness of using the Internet as a tool to facilitate the maintenance of weight lost in a behavioral weight control program.
- Trial name
- NCT00008827
- Testing
- Behavioral weight loss
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Overweight/Obese Adults
Effects of the Bifidobacterium Longum BL21 on BMI, Metabolic Indicators, and Gut Microbiota in Overweight/Obese Adults
The goal of this study is to investigate the effects of Bifidobacterium longum subspecies BL21 on BMI, metabolic indicators, and changes in gut microenvironment microbiota in overweight/obese adults.
- Trial name
- NCT06140641
- Testing
- Probiotics
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Qilu Hospital of Shandong University
Obesity
Sleep Deprivation and Energy Balance
Observational and epidemiological studies have found a link between obesity and short sleep duration with the prevalence of both increasing in the past decades.
- Trial name
- Sleep (NCT00935402)
- Testing
- Sleep
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Erectile Dysfunction
Effect of Lifestyle Changes on Erectile Dysfunction in Obese Men: a Randomized Controlled Trial
Healthy lifestyle factors are associated with maintenance of erectile function in men. To determine the effect of weight loss and increased physical activity on erectile and endothelial functions in obese men.
- Trial name
- NCT00636688
- Testing
- Lifestyle - detailed advice, Control - general information
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Healthy, Glucose Metabolism Disorders
Energy Metabolism and Acute Effects of Protein Diets in Metabolically Obese Normal Weight Individuals
Asians tend to develop type 2 diabetes (T2D) at lower body mass index (BMI) levels and younger ages compared to other populations.
- Conditions
- Healthy, Glucose Metabolism Disorders, Obesity, Visceral, Obesity; Endocrine
- Trial name
- MONW (NCT06802341)
- Testing
- Normal protein diet, Animal protein diet, Plant based diet
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Obesity
Endomina Controlled Study
The aim of this trial is to evaluate the efficacy of an endoluminal vertical gastroplasty (EVG) using an endoluminal-suturing device.
- Trial name
- NCT03255005
- Testing
- Endomina, Diet
- Where
- 2 sites in Belgium, France
- Volunteers
- 72 people
- Sponsor
- Erasme University Hospital
Obesity
One-anastomosis Gastric Bypass/Mini-Gastric Bypass Versus Roux-en Y Gastric Bypass
The aim of this prospective randomized controlled trial is to compare the two procedures One-anastomosis gastric Bypass/Mini-gastric Bypass (OAGB/MGB) and Roux-en Y gastric bypass (RYGB) in relation to intraoperative and…
- Trial name
- MGBvsRYGB (NCT03045679)
- Testing
- RYGB, OAGB/MGB
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sana Klinikum Offenbach
Sleep Apnea, Obstructive, Diabetes Mellitus, Type 2
Effect of CPAP on Myocardial Dysfunction in Type 2 Diabetes Mellitus and Obstructive Sleep Apnea Patients
This study evaluates the effect of the use of nasal CPAP in the cardiac function, measured by strain and TEI index, in patients with type 2 diabetes mellitus, obstructive sleep apnea and obesity.
- Conditions
- Sleep Apnea, Obstructive, Diabetes Mellitus, Type 2, Continuous Positive Airway Pressure, Myocardial Dysfunction
- Trial name
- NCT03221205
- Testing
- Therapeutic CPAP
- Where
- Mexico
- Volunteers
- 78 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
Obesity
Trial of a Water Beverage Intervention for Promoting Modest Weight Reduction in Free Living Adults
The primary objectives of this clinical trial are to determine if replacing sugar sweetened beverages with water consumption promote weight loss over 6 months in overweight adults and if replacing sugar sweetened beverages with…
- Trial name
- NCT01017783
- Testing
- Dietary substitution A, Dietary Substitution B, Healthy Choices
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Craving
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Food Craving in Obese Individuals.
Background: Obesity is one of the most important diseases around the globe; with a continuous increase and public health concern. Current treatments present some limitations.
- Trial name
- taVNS (NCT03217929)
- Testing
- Active-taVNS
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Obesity
Effective Weight Maintenance for the Working Age
This study aims to compare the effectiveness and adherence of three web-based weight management interventions, all based on the HealthyWeightCoaching (HWC) within a HealthyWeightHub.fi (HWH) platform.
- Trial name
- NCT04785586
- Testing
- Healthy Weight Coaching, Individual meetings, Group meetings
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Psoriatic Arthritis
Effect of Exercise and Diet on Psoriatic Arthritis
Psoriatic arthritis (PsA) is a particular pattern of inflammatory arthritis often seen in association with psoriasis. PsA patients have a higher prevalence of comorbidities including obesity, metabolic syndrome, depression and…
- Trial name
- NCT02188641
- Testing
- Diet, Exercise, Diet and Exercise
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- University of Alexandria
Prader-Willi Syndrome
Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome
The purpose of this study was to evaluate the effects of a once daily subcutaneous injectable formulation of setmelanotide in obese participants with Prader-Willi syndrome on tolerability, weight loss, and hyperphagia-related…
- Trial name
- NCT02311673
- Testing
- Setmelanotide
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Cachexia, Pancreatic Neoplasms
A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Pancreatic Cancer Related Cachexia
The purpose of this study is to evaluate the effectiveness and safety of infliximab, the active ingredient in Remicade, for the treatment of cachexia in pancreatic cancer patients who are receiving chemotherapy with gemcitabine.
- Trial name
- NCT00060502
- Testing
- Infliximab; Gemcitabine
- Volunteers
- 73 people
- Sponsor
- Centocor, Inc.
Psoriatic Arthritis, Obesity
The Effects of Weight Loss on Psoriatic Arthritis
Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. Although the underlying cause of PSA is unclear, increased body weight is known to increase the disease symptoms.
- Trial name
- NCT05393141
- Testing
- diet and biopsychosocial exercise intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Hacettepe University
Morbid Obesity
The Ultrasound Guided Versus Land-mark Location Method for Performing Spinal Anesthesia in Obese Parturients
This study will be investigated whether an ultrasound-assisted technique is better than a classical land-mark technique to facilitate spinal anesthesia in the lateral position in morbidly obese pregnant women with BMI ≥ 40 who…
- Trial name
- NCT05342922
- Testing
- Ultrasound group, Landmark group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Malnutrition, Infant, Malnutrition, Child
Efficacy of Mobile Health Application in Promotion of Exclusive Breast Feeding and Young Child Feeding Practices in Pakistan
Early life nutrition is the key modifiable determinant of child growth, development, survival and diseases of adult onset. Pakistan ranks highest for neonatal mortality rate (44.2/1000 live births (LBs)) globally.
- Trial name
- NCT05590351
- Testing
- First diet: m-health coaching application, Face to Face counselling
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Malnutrition
Prevention of Weight Loss in Long Term Care Veterans
Background: Numerous studies have shown that many LTC residents receive inadequate staff assistance with eating, which places them at risk for under-nutrition, dehydration and weight loss.
- Trial name
- NCT00841412
- Testing
- Immediate Intervention Group, Delayed Intervention Group
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- US Department of Veterans Affairs
Obesity, Nutritional and Metabolic Diseases
A Study of the Safety and Effectiveness of JNJ-16269110 (R256918) in Overweight and Obese Patients
This study investigates the effectiveness and safety of 12 weeks of treatment with JNJ-16269110 (R256918), in overweight and obese patients.
- Conditions
- Obesity, Nutritional and Metabolic Diseases, Metabolic Diseases, Nutrition Disorders
- Trial name
- NCT00622765
- Testing
- R256918
- Where
- 18 sites in Belgium, Denmark and 5 more
- Volunteers
- 321 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
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