Clinical trials: Body Weight Management
Obesity
A Study to Investigate the Safety, Tolerability, Pharmacokinetic/Pharmacodynamic Characteristics, and Food Effect of HSG4112
1. Study Objective: The objective of this phase 1 clinical trial is to evaluate the safety, tolerability, pharmacokinetic/pharmacodynamic characteristics and food effect of HSG4112 after oral administration in healthy male…
- Trial name
- NCT04732988
- Testing
- HSG4112
- Where
- 2 sites in South Korea
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Glaceum
the Management of Weight Regain After Gastric Bypass by Endoscopic Suturing
Assessment of the Overstich Technique for the Management of Weight Regain After Gastric Bypass.
Prospective multicenters randomized study to compare the efficiency and the socioeconomic impact of the endoscopic management (Overstitch technique) of weight regain after gastric bypass surgery to non invasive treatment
- Trial name
- APOLLO (NCT02048033)
- Testing
- Regular endoscopy + endogastric suturing, Regular endoscopy
- Where
- 7 sites in France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Healthy Adults
Evaluation of RSB11-HI Postbiotic Supplementation for Supporting Weight Management, Metabolic Wellness, and Quality of Life in Healthy Adults
This randomized, double-blind, placebo-controlled clinical trial will evaluate the safety, tolerability, and efficacy of RSB11-HI, a heat-inactivated postbiotic, in healthy adults over an 8-week intervention period.
- Trial name
- NCT07788833
- Testing
- RSB11-HI Heat-Inactivated Postbiotic
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Able Biolabs, LLC
Overweight, Obese
Low Level Laser Treatment (LLLT) and Lorcaserin for Weight Management
Currently in the United States about 97 million adults are considered obese, accounting for about 33% of the American adult population (compared to 22.9% in 1988).
- Trial name
- NCT02129608
- Testing
- LLLT, Lorcaserin
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Gastroenterology
Efficacy Evaluation of Dai Dai Flower on Body Weight
To assess the Dai Dai flower extract on body weight control
- Trial name
- NCT04692792
- Testing
- Dai Dai flower drink
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Exercise Training, Biomarkers
Biomarker Feedback on Health and Wellbeing and Exercise Adherence Following a 6 Month Weight Management Course
Participants who have signed up to the Watford Football Club Community and Education Trust Weight management programme called Shape Up will be approached to see if they would like to take part in this research study.
- Trial name
- NCT03809871
- Testing
- Cardiometabolic biomarkers
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Hertfordshire
Obesity, Weight Loss
Lifestyle Intervention in Overweight Women
The Exercise and Obesity Health Promotion (PESO) program is a randomized controlled trial designed to analyze the effects of a lifestyle intervention in weight management and health-related parameters of overweight and obese…
- Conditions
- Obesity, Weight Loss, Lifestyle, Sedentary, Physical Activity
- Trial name
- PESO (NCT03823898)
- Testing
- Supervised exercise, Lifestyle intervention from baseline to 4 months, Monthly behavioral sessions
- Where
- Portugal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Post Operative Analgesia, Tonsillectomy
Weight-Adjusted Diclofenac Potassium Medicated Lollipop for Post-Adenotonsillectomy Pain in Children
Brief Summary This study aimed to develop and conduct a preliminary clinical evaluation of a novel weight-adjusted gelatin-based diclofenac potassium medicated lollipop for the management of postoperative pain following…
- Conditions
- Post Operative Analgesia, Tonsillectomy, Pediatric Anesthesia
- Trial name
- DICLOPOP (NCT07646093)
- Testing
- Diclofenac Potassium Medicated Lollipop
- Where
- Venezuela
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario de Caracas
Obesity
Evaluation of the Shape Up Rhode Island Campaign Study 5
Obesity is a major health problem that has reached epidemic levels. Efforts are needed to develop cost-effective public health approaches for weight loss and maintenance.
- Trial name
- NCT00948415
- Testing
- Evaluation of the Shape Up RI Campaign
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Inflammatory Response, Obesity
Thymol on Netrin-1 on Obese Patients
The prevalence of obesity in Mexico is 35.4%, and it is considered a risk factor for the development of diabetes, systemic arterial hypertension and dyslipidemia.
- Trial name
- NCT05427721
- Testing
- Thymol
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centro Universitario de Ciencias de la Salud, Mexico
Childhood Obesity
Mountain West Prevention Research Center Core Research Project
This hybrid type 3 effectiveness-implementation sequential multiple assignment randomized trial will assess the impact of integrating population health management (PHM) strategies-text messaging and enrollment in Building Healthy…
- Trial name
- MW-PRCCRP (NCT07479498)
- Testing
- Text Message-based recruitment, Active outreach follow-up
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Paul Estabrooks
Obesity in Pregnancy
Best Start - Weight Management During Pregnancy
The investigators know that being overweight during pregnancy increases the health risks to both mum and baby. There is good evidence that diet or exercise, or both, during pregnancy can reduce excessive weight gain.
- Trial name
- NCT03875300
- Testing
- Foodwise in Pregnancy
- Where
- 4 sites in United Kingdom
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- Cwm Taf University Health Board (NHS)
Obesity Prevention
Better4All Personalized Intervention Pilot Study
The BETTER4U project (Preventing obesity through Biologically and bEhaviorally Tailored inTERventions for you) is funded by the European Union (EU) and involves an international consortium consisting of 28 partners across Europe…
- Trial name
- BETTER4ALL (NCT07120802)
- Testing
- BETTER4U Mobile App and Wearable Use (End-User Group), BETTER4U Intervention Platform Testing (Implementer Group)
- Where
- 7 sites in Cyprus, France and 5 more
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Diabetes Mellitus, Type II, Overweight and Obesity
Microclinic Social Induction Pilot Intervention for Diabetes and Obesity Management in Qatar
The purpose of the study is to pilot-phase test the effectiveness of the microclinic social induction model and its effects on behavioral and metabolic outcomes in different levels of social and familial relationships in Qatar.
- Conditions
- Diabetes Mellitus, Type II, Overweight and Obesity, Hypertension, Behavioral Lifestyle Change
- Trial name
- NCT02175537
- Testing
- Microclinic Social Induction Diabetes and Obesity Program
- Where
- Qatar
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Microclinic International
Weight Loss, Obesity
Development and Effectiveness of Cognitive Behavioral Therapy Based Weight Control Mobile Application "BI'KILO"
The primary purpose of this project is to observe the effects of Cognitive Behavioral Psychotherapy-based weight-loss mobile application (Bi' Kilo) in 4 essential areas (Anthropometric, Biochemical, Psychometric, Cognitive) in…
- Conditions
- Weight Loss, Obesity, Overweight and Obesity, Eating Behavior
- Trial name
- NCT06359236
- Testing
- BI'KILO Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Overweight and Obesity
MyGeneMyDiet Trial for Weight Management
The study aims to determine if genotype-based nutrition and lifestyle advice is effective for the management of overweight and obesity among Filipino adults compared to the usual standard of care.
- Trial name
- NCT05098899
- Testing
- MyGeneMyDiet® Recommendations for Weight Management, Usual Standard of Care for Weight Management
- Where
- Philippines
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Food and Nutrition Research Institute, Philippines
Weight Management
Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)
The goal of this clinical study is to learn more about the study drug, GS-4571, and how safe it is in 3 groups, i) Healthy participants, ii) Healthy non-diabetic obese participants, and iii) Non-obese participants with Type 2…
- Trial name
- NCT06562907
- Testing
- GS-4571, Omeprazole
- Where
- 3 sites in United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Overweight, Obesity
Safety and Efficacy of Medicinal Plant Extract in Overweight and Obese Participants.
The purpose of this randomized , double -blind clinical trial is to evaluate the efficacy and safety of a daily administration of Nitraria retusa extract in overweight and obese participants, during 10 days.
- Trial name
- NCT05824039
- Testing
- Tea infusion
- Where
- Tunisia
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Laouani Aicha
Overweight, Obese
AZD7687 Multiple Ascending Dose Study
The aim of the study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD7687 following multiple ascending dose administrations in in overweight to obese but otherwise healthy male subjects
- Trial name
- NCT01119352
- Testing
- AZD7687
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Chronic Weight Management
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASC35 Injection in Participants With Obesity or Overweight
This randomized, double-blind, placebo-controlled single ascending dose (SAD)/ multiple ascending dose (MAD) study is designed to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of ASC35 injection
- Trial name
- NCT07842640
- Testing
- ASC35 Injection B, for subcutaneous use, Tirzepatide
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ascletis Pharma (China) Co., Limited