Clinical trials: Bone Fracture
Bariatric Surgery, Osteoporosis
Skeletal Health in Bariatric Surgery Patients
The investigators propose a prospective cohort trial that will help to understand the impact of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in pre- and post-menopausal female bariatric patients.
- Conditions
- Bariatric Surgery, Osteoporosis, Fractures, Bone, Roux En-Y Gastric Bypass
- Trial name
- NCT03331536
- Testing
- Roux en Y Gastric Bypass Pre-menopausal, Roux en Y Gastric Bypass Post-menopausal, Sleeve Gastrectomy Pre-menopausal
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Denosumab Allergy
Denosumab and Screw Fixation for Osteoporotic Compression Fracture
Evaluation of bone mineral density and function at 1 year after screw internal fixation of osteoporotic vertebral compression fractures with desuzumab: a parallel double-blind randomized controlled clinical trial
- Trial name
- NCT05065164
- Testing
- Denosumab Only Product
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shenzhen People's Hospital
Stress Reaction
Breaking Bad News - Optimizing Stress Response and Communication Performance in Medical Students
Breaking bad news (e.g., telling patients that they have cancer) is not only very stressful for the patients concerned, but also for the physicians delivering the diagnosis.
- Trial name
- BPSM (NCT05037318)
- Testing
- Stress arousal reappraisal, Worked examples
- Where
- Switzerland
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- University of Bern
Nonunion Fracture
The Efficacy of Mesenchymal Stem Cells for Stimulate the Union in Treatment of Non-united Tibial and Femoral Fractures in Shahid Kamyab Hospital
Because the rate of non union of long bone in lower extremities specially in tibia in this two last decade due to malnutrition and smoking and other risk factors was increased, so many patient in our country suffer from non union…
- Trial name
- NCT01788059
- Testing
- injection the mesenchymal stem cell in non union site
- Where
- Iran
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Emdadi Kamyab Hospital
Surgical Procedure, Unspecified
Posterior Wall Osteotomy for Old Acetabular Fracture
Posterior wall osteotomy would be conducted to manage the old acetabular fracture. The outcome was reviewed to assess the feasibility of the surgical procedure.
- Trial name
- osteotomy (NCT03193840)
- Testing
- posterior wall osteotomy
- Where
- 2 sites in China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hebei Medical University Third Hospital
Health, Subjective, Nutrition Disorders
Relative Energy Deficiency in Sport Multicenter Study
Relative Energy Deficiency in Sport (RED-S) characterizes a range of negative health and performance outcomes that result from chronically low energy availability.
- Conditions
- Health, Subjective, Nutrition Disorders, Athletic Injuries, Hormone Disturbance
- Trial name
- NCT04766203
- Testing
- Treatment of REDS using a holistic treatment arm
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Trent Stellingwerff
Osteogenesis Imperfecta
Osteogenesis Imperfecta Blood Pressure Study
Osteogenesis Imperfecta (OI) is a genetic disorder caused by mutations to the alpha-1 or alpha-2 chain of type I collagen. Clinically, the disorder is characterized by bones that fracture easily, often from little or no apparent…
- Trial name
- NCT04169568
- Testing
- Manual cuff blood pressure
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Osteoporosis, Fracture
Bone Microarchitecture in Women With and Without Fracture
Osteoporosis is a common disorder of compromised bone strength causing 40-50% of women and ~25% of men to sustain fragility fractures during their lifetime.
- Trial name
- mMRI (NCT01049191)
- Where
- 2 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Ankle Fractures, Splints
Post Operative Ankle Splint Study - Prospective Multi Center Randomized Controlled Trial
Background: Ankle fractures are some of the most common orthopedic presentations, however, controversy in their management and their post-operative rehabilitation protocols exist.
- Trial name
- PASS (NCT04796168)
- Testing
- Splinting (plaster of paris)
- Where
- Kuwait
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kuwait Institute for Medical Specialization
Stress Fracture
Calcium and Vitamin D Supplementation Decreases Incidence of Stress Fractures in Female Navy Recruits
We conducted a double-blind, placebo-controlled randomized clinical trial of calcium and vitamin D supplementation in 5201 female Naval recruits.
- Trial name
- NCT00476346
- Testing
- Calcium & Vitamin D
- Where
- United States
- Volunteers
- 5,201 people, healthy volunteers welcome
- Sponsor
- Creighton University
Trauma, Rehabilitation
NMES and Pelvic Fracture Rehabilitation
Objectives: The acute care of pelvic fractures has improved recently however there are no formal guidelines for rehabilitation of these types of fractures. Patients have long periods of non-weight bearing causing muscle wastage.
- Trial name
- NCT03278834
- Testing
- Neuromuscular muscle stimulation machine- Strength Setting, Neuromuscular muscle stimulation machine - TENS Setting
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Distal Radius Fractures, Wrist Fracture
Unstable Distal Radius Fractures With Dorsal Dislocation in Patients Aged 18-64 Years. Volar Locking Plate (VLP) vs Closed Reduction and Percutaenous Pinning (CRPP).
120 patients age 18-64 years with dorsally displaced distal radius fractures AO-type A2, A3 and C1 are recruited from Oslo Casualty Medical Centre (Oslo Skadelegevakt).
- Conditions
- Distal Radius Fractures, Wrist Fracture, Colles' Fracture
- Trial name
- NCT04716309
- Testing
- Open reduction and volar locking plate and closed reduction and K-wires.
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Distal Radius Fractures
Do Generic Volar Locking Plates Provide Similar Outcomes at a Reduced Cost?
Across orthopedics, the investigators will be using the generic volar locking plates for patients undergoing open reduction and internal fixation (ORIF) of the distal radius using a block schedule, meaning one month we the…
- Trial name
- NCT06343467
- Testing
- Generic Volar Locking Plate, Conventional Volar Locking Plate
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Distal Radius Fracture
Above-versus Below-elbow Casting for Conservative Treatment of Distal Radius Fractures
For the non-surgical treatment of distal radius fractures in adults a variety cast options are available, including or not the elbow joint.
- Trial name
- NCT03126175
- Testing
- Below elbow immobilization, Above elbow immobilization
- Where
- Brazil
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hospital Dr. Fernando Mauro Pires da Rocha
Tendon Repair, Fracture Repair
A Single-center, Prospective, Clinical Study of VersaWrap Utilization in the Hand
The purpose of this study is to evaluate the efficacy on the use of VersaWrap® in surgery of the hand/fingers, including tendon repair, fracture repair, or tenolysis of the hand/fingers.
- Conditions
- Tendon Repair, Fracture Repair, Tenolysis
- Trial name
- NCT05598801
- Testing
- VersaWrap
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Research Source
Fracture Nonunion, Infection
Smoking Cessation in Nonunion, Malunion, Osseous Infection
The Study Investigators have seen high rates of tobacco cessation success combining Chantix with the risk of no surgery, should tobacco use continue.
- Trial name
- nicotine (NCT00754299)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Tooth Fractures, Tooth Injuries
Comparative Volumetric Assessment of Alveolar Ridge Preservation Utilizing Different Bone Grafting Materials
This study is intended to provide statistically robust evidence that Symbios Demineralized Cortical-cancellous granule mix, Symbios OsteoGraf LD-300, and OsteoGraf/N-300 combined with Symbios OsteoShield Collagen Resorbable…
- Conditions
- Tooth Fractures, Tooth Injuries, Tooth Diseases
- Trial name
- NCT02532543
- Testing
- Allograft, Membrane, Alloplast, Membrane, Xenograft, Membrane
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Tibial Fractures, Malleolar Fractures
Intramedullary Nailing of Tibia Fractures
Currently, the treatment of choice for tibial fracture is intramedullary nailing. This procedure has been shown to have low rates of infection, high rates of bone healing, and a faster return to weight bearing and activity in…
- Trial name
- NCT01797640
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Utah
Hip Fractures
Comparative Study to Evaluate the Efficacy of Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Versus Fascia Iliaca Compartment (FIC) Block on the Postoperative Analgesic Effect in Patients Undergoing Hip Surgeries Under Spinal Anesthesia.
Fractures in and around the hip are quite common irrespective of both the young and elderly population groups and are associated with extreme pain.
- Trial name
- NCT05751291
- Testing
- Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sohag University
Dental Implant, Narrow Implant
Comparison Between Ultra-narrow Diameter Implants (2,75 mm) Without Bone Regeneration Versus Standard Diameter Implants (4,3 mm) in Combination With Bone Regeneration
The main target of the study is to compare ultra-narrow diameter implants (2.75 mm) without bone regeneration versus standard diameter implants (4.3 mm) in combination with bone regeneration.
- Conditions
- Dental Implant, Narrow Implant, Implant Fracture, Guided Bone Regeneration
- Trial name
- NCT03225495
- Testing
- Standard implant, Ultra-narrow implant
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Barcelona