Clinical trials: Bone Geometry
Osteoporosis in Post-menopausal Women
Bone Health in Postmenopausal Women: The Effect of Exercise With or Without Medication for Osteoporosis
Osteoporosis is a systemic bone disorder characterised by a reduced bone mass and structural deterioration, increasing the risk of fragility fractures, particularly in women post-menopause.
- Trial name
- BEAT-OP (NCT07267325)
- Testing
- EXERCISE TRAINING, Antiresorptive medication (routine clinical care)
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Anorexia Nervosa
Effect Of Biomechanical Stimulation On Skeletal Health In Adolescent And Young Women With Anorexia Nervosa
This study will evaluate the effects of a novel, non-pharmacologic intervention for the prevention of deleterious changes in bone density and strength in adolescents with anorexia nervosa (AN), a disease commonly treated with…
- Trial name
- NCT01100567
- Testing
- Low-magnitude mechanical stimulation platform
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Boston Children's Hospital
Osteoporosis
S-32 PG 242 Short Stem
The data of calibrated CT-scans will be used for the Finite Element Analysis (FEA) analysis for SMR Short Stem in identified hospitals in EU and US as developers of the project and for further research, upon subject acceptance.
- Trial name
- NCT05083728
- Testing
- CT
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- St. Louis Joint Replacement Institute
Osteoporosis
Effect of Physical Activity in Women With Manifest Osteporosis
Objectives: To investigate if a physical activity intervention (one year) can reduce the risk of falls (primary endpoint), improve physical function (balance and muscle strength) and cortical bone geometry as well as trabecular…
- Trial name
- NCT04768712
- Testing
- Weight bearing aerobic exercise
- Sponsor
- Sahlgrenska University Hospital
Implant Geometry, Osseointegration, Soft Tissue Volume, Marginal Bone Levels, Soft Tissue Recession, Volumetric Analysis
The Influence of a New Implant Neck Configuration on Hard and Soft Tissue Healing
Title: Randomized Controlled Clinical Trial comparing two dental implants with different neck configurations. Objective: To evaluate the changes in peri-implant soft tissues and marginal bone level when using a one-piece implant…
- Trial name
- NCT04308083
- Testing
- dental implant placement
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- PerioCentrum Research
Postmenopausal Osteoporosis
Dried Plums and Bone Health in Postmenopausal Women
Postmenopausal women often seek non-pharmacologic interventions for the protection of bone health. Previous research in humans and rodents has indicated that dietary dried plum consumption may be beneficial for bone health…
- Trial name
- NCT02822378
- Testing
- Dried Plum, Calcium supplement, Vitamin D supplement
- Where
- United States
- Volunteers
- 322 people
- Sponsor
- Penn State University
Stress Fractures, Bone Geometry
Bone Geometry, Strength, and Biomechanical Changes in Runners With a History of Stress Fractures
Stress fractures are a common and debilitating injury for a variety of athletes however current evidence does not clearly allow easy prediction of athletes at risk for a first fracture.
- Conditions
- Stress Fractures, Bone Geometry, Bone Strength, Biomechanical Changes
- Trial name
- NCT00766077
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Utah
Femur Fracture, Childhood
Study of the Geometry of the Immature Human Femur Before the Age of 3 Years From Data Measured on CT Scan
Childhood fractures are the second most common presentation of abuse. The target population for screening for these injuries is children under the age of three who are unable to express themselves about the circumstances of the…
- Trial name
- GFI (NCT05620394)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Breast Cancer
Bone Geometry and Muscle Density Changes in Postmenopausal Women and Breast Cancer Patients Prescribed Anastrozole
The primary objective of this study is to determine if trabecular or cortical volumetric bone mineral density (vBMD) change over time in postmenopausal breast cancer patients who are prescribed Anastrozole, as measured by pQCT at…
- Trial name
- NCT00421447
- Testing
- Anastrozole
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- Hamilton Health Sciences Corporation
Bone Density, Gonadal Steroid Hormones
SIBlos EXtension Study (SIBEX)
Population-based, longitudinal cohort study designed to evaluate changes in bone mineral density, bone geometry, body composition, parameters reflecting muscle force, and sex steroid status in healthy young men, as well as their…
- Conditions
- Bone Density, Gonadal Steroid Hormones, Thyroid Hormones
- Trial name
- NCT02997033
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 709 people, healthy volunteers welcome
- Sponsor
- University Ghent
Adult Onset Growth Hormone Deficiency
Bone Structure in Patients With Adult Onset Growth Hormone Deficiency Assessed Using High Resolution Peripheral Quantitative Computed Tomography
The aim of the study is to assess bone geometry, bone compartment specific volumetric densities and micro-architecture as well as to evaluate non-invasive estimates of bone strength in patients with adult onset growth hormone…
- Trial name
- NCT02218710
- Where
- 3 sites in Denmark
- Volunteers
- 45 people
- Sponsor
- Odense University Hospital
Osteopenia, Postmenopausal Osteopenia
Design and Development of a Novel Food Supplement for Osteoporosis Based on Gut Microbiome Mechanisms
It is well proven that the intestinal microbe regulates bone metabolism by the absorption of calcium and other metallic trace elements.
- Trial name
- OSTEOME (NCT05421819)
- Testing
- Calcium and vitamin D supplement, Calcium, vitamin D and prebiotic supplement, Calcium, vitamin D and flavonoid supplement
- Where
- Greece
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Implant Geometry
Bone-To-Implant Contact At 4- And 6-Week Healing Stages in Implants With Different Surfaces.
Objective: Implant surface topography is a key element in achieving osseointegration. Nanostructured surfaces have shown promising results in accelerating and improving bone healing around dental implants.
- Trial name
- NCT05558800
- Testing
- Implant placement
- Where
- Lebanon
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Pectus Excavatum, Funnel Chest
Optical Surface Imaging Versus Conventional Photography as a Tool to Document the Surface Geometry of Pectus Excavatum
Pectus excavatum is the most common congenital anterior chest wall deformity, known to occur in 1:400 of new-borns. Complaints may be of cosmetic nature or as a consequence of (cardio)pulmonary impairment.
- Trial name
- NCT04185870
- Testing
- 3D scan, Standard photography
- Where
- Netherlands
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
X-linked Hypophosphatemia, Hereditary Hypophosphatemia
Characterising Pain, QoL, Body Composition, Arterial Stiffness, Muscles and Bones in Adult Persons With XLH and Healthy Controls
Hereditary hypophosphatemia (XLH) is a rare, inherited disease. Loss-of-function mutation in the phosphate regulating gene with homologies to endopeptidases on the X-chromosome (PHEX) results in excess fibroblast growth factor 23…
- Trial name
- NCT04273490
- Where
- Denmark
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Graves' Disease
D-vitamin And Graves' Disease; Morbidity And Relapse Reduction
The purpose of this study is to investigate the effects of vitamin D supplementation on morbidity and risk of relapse in patients with Graves' disease.
- Trial name
- DAGMAR (NCT02384668)
- Testing
- Cholecalciferol
- Where
- 8 sites in Denmark
- Volunteers
- 278 people
- Sponsor
- University of Aarhus
Exercise, Healthy
Bone and Body Composition Adaptations to Physical Training
The goal of this clinical trial is to evaluate how different exercise programs alter bone density, structure, and strength in adults.
- Trial name
- BoBCAT (NCT06972862)
- Testing
- Osteogenic Index Optimized Exercise Training Program
- Where
- 2 sites in United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh