Clinical trials: Bone Healing
Bone Loss
Evaluation of Using Different Screwed Abutment Height
A prospective randomized controlled clinical trial will be conducted. Study groups will be assigned as described above. The patients will be randomly divided into two groups in order to study the influence of prosthetic screw…
- Trial name
- NCT06017115
- Testing
- Dental implant placement with COVER SCREW (two surgeries in control group) or DEFINITIVE TRANSEPITHELIAL ABUTMENT (one surgery in test group)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Tooth Replacement
Dental Implant Study Comparing Two Types of Metals Used for Dental Implants
The purpose of this research study is to compare the healing differences of two metals (trabecular vs. standard titanium) that are used for dental implants.
- Trial name
- ZMU (NCT01714024)
- Testing
- Zimmer Trabecular Metal Test Cylinder, Zimmer Titanium Test Cylinder
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Wound Healing, Bone Regeneration
Fucoidan(Seaweed) Based Gel Around Immediate Implants
The current study is a prospective randomised parallel mouth study to evaluate the effect of Fucoidan gel around immediate implant to assess the wound healing and bone regeneration in comparison to regular implant placement…
- Trial name
- NCT07736287
- Testing
- Fucoidan extracted from F. Vesiculosus, immediate implant placement
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Osteopenia, Osteoporosis
Calcium-Rich Food Versus Calcium Carbonate for Bone Health
This study will compare adherence, tolerability, safety, and treatment satisfaction between a calcium-rich food and a traditional calcium carbonate supplement in women ages 40 to 90 who are at increased risk for osteoporosis.
- Conditions
- Osteopenia, Osteoporosis, Bone Health in Perimenopausal Women, Menopause Related Conditions
- Trial name
- NCT07763509
- Testing
- 500 mg calcium from milk-derived minerals, Calcium Carbonate 500 MG
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Cornell University
Alveolar Bone Loss
A Clinical Investigation to Evaluate the Healing of Tooth Extraction Sites Filled With BioRestore™
The aim of this study was to evaluate by histology and MSCT scans during a 7-month period, the efficacy of a bioactive glass (Inion BioRestore™) placed in human extraction sockets in the maintenance of alveolar ridge.
- Trial name
- NCT01105026
- Testing
- Alveolar Bone Defect Regeneration Following Tooth Extraction
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Implant Geometry, Osseointegration, Soft Tissue Volume, Marginal Bone Levels, Soft Tissue Recession, Volumetric Analysis
The Influence of a New Implant Neck Configuration on Hard and Soft Tissue Healing
Title: Randomized Controlled Clinical Trial comparing two dental implants with different neck configurations. Objective: To evaluate the changes in peri-implant soft tissues and marginal bone level when using a one-piece implant…
- Trial name
- NCT04308083
- Testing
- dental implant placement
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- PerioCentrum Research
Ankle Fractures
Postoperative Aspirin and Ankle Fracture Healing
This study aims to identify if postoperative aspirin use leads to a delay in fracture healing. NSAIDs have long been avoided in the management of fractures, due to the belief that they may impair fracture healing.
- Trial name
- NCT03765619
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Edentulous; Alveolar Process, Atrophy
Bone Healing at Non-submerged Implants Installed With Different Insertion Torques.
The objective of the study is to evaluate histomorphometrically the healing at implants installed with standard or very low insertion torque values.
- Trial name
- NCT04017156
- Testing
- implant installation
- Where
- Colombia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Peri-implant Tissue Response With Use of Customized Healing Abutments
Effect of Customized Healing Abutments on Peri-implant Soft Tissue and Bone
The goal of this clinical trial is to evaluate effect of customized healing abutment in patients who need single implant reconstruction.
- Trial name
- NCT06125418
- Testing
- customized healing abutment, standard healing abutment
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Extraction Socket Healing, Extraction, Tooth
The Effect of Collagen In Tooth Extraction Procedures
This study is aimed at assessing the effect of an animal-derived collagen matrix on bone and soft tissues in the human teeth. Single-rooted teeth that are beyond restoration and in need of extraction will be included in the…
- Trial name
- NCT07270510
- Testing
- Collagen Matrix soft tissue graft
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Post-Extraction Socket Hemostasis, Post-Extraction Socket Pain Relief
Comparison of A-PRF vs Bone Wax in Hemostasis, Pain Relief and Healing Following Exodontia
The goal of this clinical trial is to compare the pain relief and healing effect of A-PRF and Bone-wax in patients having mandibular tooth-extractions.
- Conditions
- Post-Extraction Socket Hemostasis, Post-Extraction Socket Pain Relief, Post-Extraction Socket Healing
- Trial name
- NCT05744726
- Testing
- A-PRF, Bone-wax
- Where
- Pakistan
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Radius Fractures
Association Between Hand-Eye Coordination and Handgrip Strength in Children Post-Healing of DRGF
The study investigates whether hand-eye coordination is related to handgrip strength in children (aged 5-12 years) after they have healed from distal radius greenstick fractures.
- Trial name
- NCT07037355
- Testing
- Handgrip Strength and Hand-Eye Coordination Assessment
- Where
- Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Superior University
Osteoarthritis, Knee, Fractures, Ununited
Modern Methods of Treatment and Diagnosis of Patients With Injuries and Diseases of the Musculoskeletal System
Brief Summary This clinical study investigates the safety and effectiveness of combining advanced regenerative therapies with personalized surgical technology for patients with delayed fracture healing (non-unions), knee…
- Conditions
- Osteoarthritis, Knee, Fractures, Ununited, Arthroplasty, Replacement, Knee
- Trial name
- MTDMS (NCT07628010)
- Testing
- Autologous Mesenchymal Stromal Cells Combined with Platelet-Rich Plasma, Patient-Specific 3D-Printed Surgical Instruments
- Where
- Ukraine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zaporizhzhiya State Medical University
Bone Healing
Maxillary Sinus Augmentation by Xenograft Mixed With Melatonin
The possibility of enhancing the bone substitute in the maxillary sinus by mixing it with the melatonin to allow proper implant placement in early stage .
- Trial name
- melatonin (NCT06736821)
- Testing
- Open sinus augmentation with melatonin gel mixed with xenograft, Open sinus augmentation with xenograft
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- rehab soliman
Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth
To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.
This study will compare commercially available, commonly used mouth rinses (0.12% chlorhexidine (CHX) vs. Ethylenediaminetetraacetic acid (EDTA)) for immediate post-operative and daily antiseptic use after tooth extraction and…
- Trial name
- NCT07191262
- Testing
- 0.12% CHX and Essential Oil mouthrinse, 2.6% EDTA and 0.2% EDTA mouth rinse
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Alveolar Bone Resorption
Guided Bone Regeneration in Alveolar Socket
Following tooth extraction, volumetric changes in the soft and hard tissues of the extraction site are expected to occur with considerable resorption of the alveolar bone in both the vertical and the horizontal dimensions.
- Trial name
- GBR_socket (NCT05577663)
- Testing
- Routine treatment of the extraction socket, Socket seal technique by a free gingival graft, Socket seal technique using a synthetic resorbable membrane
- Where
- Greece
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Tooth Extraction
Wound Healing Following Tooth Extraction and Ridge Preservation Using OsteoGen®
After the removal of a tooth, a bone graft is often placed in the socket to try to keep the volume of bone that was there when the tooth was present so that the bone does not "shrink".
- Trial name
- NCT07154693
- Testing
- Combination 70% FDBA and 30% DFDBA, OsteoGen Plug
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Inflammatory Bowel Diseases
Regulation of Mucosal Healing in Inflammatory Bowel Disease
The objective of the current study is to compare non-healing colonic ulcers in patients with inflammatory bowel disease (IBD) with iatrogenic colonic ulcers (biopsy sites) in healthy control patients and patients with rheumatoid…
- Trial name
- NCT04504136
- Testing
- Serial Biopsy
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Terrence A Barrett
Patients Diagnosed With Persistent Apical Periodontitis in Maxillary Anterior Regions Require Endodontic Microsurgery
Bone-Bioactive Liquid as an Adjunct in Endodontic Surgery
This randomized controlled clinical trial will include patients indicated for endodontic microsurgery due to persistent periapical lesions. Participants will be randomly allocated into two groups.
- Trial name
- NCT07879482
- Testing
- Bone Bioactive Liquid in endosurgery, conventional endodontic surgery
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Bio-Oss; Mucograft
Bone Volume Changes After Socket Preservation Using Geistlich Bio-Oss Collagen and Mucograft Seal
Evaluation of Bone volume Changes after socket preservation using Geistlich Bio-Oss® Collagen and Geistlich Mucograft® Seal compared to natural healing after tooth extraction
- Trial name
- NCT03395145
- Testing
- Geistlich Bio-Oss® Collagen and Geistlich Mucograft® Seal
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus