Clinical trials: Bone Health
Age-Related Osteoporosis
Dose-dependent Effects of Vitamin D on Bone Health
We propose to conduct a randomized double blind trial of three doses of vitamin D, 400, 4000, and 10,000 International Units (IU) per day, to assess the effect on bone density and architecture as assessed by high resolution…
- Trial name
- NCT01900860
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Epilepsy, Pregnant Woman
Bone Management in Pregnancy Outcomes in Epilepsy
This study is aimed to evaluate the efficacy of bone health management in improving pregnancy outcomes among WWE, and establish evidence-based vitamin D supplementation strategies for childbearing-age WWE.
- Conditions
- Epilepsy, Pregnant Woman, Bone Health
- Trial name
- NCT07651709
- Testing
- Supplementation with calcium + vitamin D daily.
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Sickle Cell Disease, Vitamin D Deficiency
High Dose Vitamin D Supplementation in Children With Sickle Cell Disease
Suboptimal vitamin D status is well reported in sickle cell disease (SCD) patients and associated with a negative impact on health-related quality of life (HRQL).
- Conditions
- Sickle Cell Disease, Vitamin D Deficiency, Health Related Quality of Life, Hand Grip Strength
- Trial name
- NCT06274203
- Testing
- Vitamin D3
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Forearm Muscle Strength, Radial Bone Health
SUPERVISED RESISTANCE AND WEIGHT-BEARING EXERCISE IN INSTITUTIONALIZED OLDER ADULTS
This quasi-experimental controlled study evaluated the effects of a six-month supervised resistance and weight-bearing exercise program on forearm muscle strength and radial bone health in institutionalized older adults.
- Conditions
- Forearm Muscle Strength, Radial Bone Health, Institutionalized Older Adults Keywords / MeSH
- Trial name
- SRWBE (NCT07831031)
- Testing
- Forearm-Focused Resistance and Upper-Extremity Weight-Bearing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Peri-Implantitis, Bone Loss in Jaw
An Evaluation of Salivary Oxidant and Antioxidant Levels in Peri-implant Health and Disease
Objectives: Inflammatory lesions develop in the tissues surrounding implants are referred to as peri-implant diseases. Oxidants, play a role in inflammatory lesions.
- Conditions
- Peri-Implantitis, Bone Loss in Jaw, Dental Implant Failed, Dental Implant Failure Nos
- Trial name
- NCT05724706
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Biruni University
Stroke
The Effects of Whole Body Vibration in People With Chronic Stroke
Whole body vibration (WBV) has been found to be useful in promoting bone health and muscle performance in older adults. To date, no study has examined the effects of different WBV frequencies on the properties of the muscle-bone…
- Trial name
- NCT03982251
- Testing
- High frequency whole body vibration, Low frequency whole body vibration
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Bone and Bones, Osteoporosis Risk
Nutritional Supplement and Bone Health in Post-Menopausal Women
The process of bone remodeling exhibits pronounced diurnal pattern that is important for bone health. A balanced rate of bone resorption is required to maintain bone health, a balance that can be disturbed during the lifecycle to…
- Conditions
- Bone and Bones, Osteoporosis Risk, Osteoporosis, Postmenopausal
- Trial name
- MBPS (NCT03337971)
- Testing
- MBPM
- Where
- Ireland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Bone Density Increased, Body Height
Milk Supplementation and Bone Health in Children
Objectives: to examine the effects of a Yili child formula milk and regular milk on bone health and growth in young children. Study design: cluster randomized controlled trial.
- Trial name
- NCT05074836
- Testing
- Formula milk, Regular milk, Control foods
- Where
- China
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Osteoporosis
Investigation of the Effect of BONISTEIN(R) Bone Blend on Bone Mineral Density/Content and Biomarkers of Bone Health
The purpose of this study is to obtain information about the effect of a combination of genistein, PUFAs, vitamin K and D (BONISTEIN(R) bone blend) on bone health, determined as bone mass density/content and bone biomarkers after…
- Trial name
- NCT00698984
- Testing
- BONISTEIN(R) bone blend
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Overweight, Obesity
Does Dairy Benefit Bone & Body Composition in Overweight Girls Undergoing a Weight Management Program?
The purpose of this study is to examine whether increased dairy intake, at the level recommended by Canada's Food Guide, combined with healthy eating and exercise, will improve body composition and bone turnover over 12 weeks in…
- Conditions
- Overweight, Obesity, Children
- Trial name
- NCT02581813
- Testing
- I.D.E.A.L. for Adolescents Study - Higher Dairy, I.D.E.A.L. for Adolescents Study - Lower Dairy
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Brock University
Osteoporosis, Postmenopausal
Quercetin's Effect on Bone Health and Inflammatory Markers
Quercetin is a plant-based flavonoid that is naturally found in many fruits and vegetables, and is considered to be a potent antioxidant with several expected health benefits such as anti-inflammatory effects and bone-conserving…
- Trial name
- NCT05371340
- Testing
- Quercetin (500 mg)
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Nutrition, Healthy, Dietary Deficiency
Health Effects of Biostimulated Lettuce in Human
The aim of the project is to study the influence of biostimulate crops on a healthy population in order to assess influence on hematological parameters and specific metabolism (glucose, lipid, iron, bone) and gut and lipid…
- Conditions
- Nutrition, Healthy, Dietary Deficiency, Bone Resorption, Glucose Metabolism Disorders
- Trial name
- NUTRIWEED23 (NCT05971017)
- Testing
- Control Group, Biostimulated group
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Bone Health, Vascular Health
Biocomparison Study
The effects of two vitamin K-forms on carboxylation of the vitamin K-dependent proteins osteocalcin and matrix-gla protein will be compared after supplementing these vitamins in a nutritional dose range.
- Trial name
- NCT01638182
- Testing
- Vitamin K1-capsules, Vitamin K2-capsules
- Where
- Netherlands
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Contraception, Estrogen Deficiency
Effect of Oestrogen on Musculoskeletal Outcomes
This cross-sectional comparison and prospective cohort design study will investigate differences in calcium metabolism, biochemical markers of bone and reproductive health, musculoskeletal health, and iron status between women…
- Conditions
- Contraception, Estrogen Deficiency, Estrogen Excess
- Trial name
- E2 (NCT05587920)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Army Health Branch, British Army
Clonal Hematopoiesis, Clonal Hematopoiesis of Indeterminate Potential
CHIP in Health and Disease
Clonal hematopoiesis (CH), including clonal hematopoiesis of indeterminate potential (CHIP), is an age-associated condition characterized by the expansion of hematopoietic stem and progenitor cell clones carrying acquired somatic…
- Conditions
- Clonal Hematopoiesis, Clonal Hematopoiesis of Indeterminate Potential, Clonal Cytopenia of Undetermined Significance (CCUS), Myelodysplastic Syndrome
- Trial name
- CHIP2 (NCT07780552)
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Fall Prevention, Bone Health
Strong Foundations 2.0: A Digitally Delivered Fall Prevention Program.
Study Description: The investigators propose to extend earlier research conducted during a feasibility study (Strong Foundations 1.0) by enrolling participants who have a greater risk for falling (x4 cohorts of up to 15…
- Conditions
- Fall Prevention, Bone Health, Balance
- Trial name
- SF2 (NCT05910606)
- Testing
- Digital Exercise
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Musculoskeletal Diseases
Effects of Nurse-led Patient Pathways
Objectives: This quasi-experimental pre-post-study investigated the effect of newly developed Nurse-led Patient Pathways (NPP) designed to improve patients', and health care professionals' as well as institutional outcomes.
- Trial name
- NPP (NCT02543307)
- Testing
- Nurse-led Patient Pathways
- Where
- Switzerland
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- Zurich University of Applied Sciences
Overweight, Glucose Metabolism Disorders
The Physical Activity and Nutrition in Children (PANIC) Study
The Physical Activity and Nutrition in Children (PANIC) Study is a single-centre controlled trial on the effects of a combined physical activity and dietary intervention on cardiometabolic risk factors and other health outcomes…
- Conditions
- Overweight, Glucose Metabolism Disorders, Lipid Metabolism Disorders, Blood Pressure
- Trial name
- PANIC (NCT01803776)
- Testing
- lifestyle counseling
- Where
- Finland
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Osteoporosis, Osteoarthritis
Resistance Exercise Training to Improve Bone and Articular Cartilage Health in Women
Osteoarthritis (degenerative joint disease) and osteoporosis (weak and fragile bones) are common conditions, particularly in women after menopause, and become even more common as we get older.
- Trial name
- REPROOF (NCT05889598)
- Testing
- Ballistic Resistance Lower Body Strength Training, Conventional Resistance Lower Body Strength Training
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Diabetes, Hypertension
Evaluation of Exercise Benefits to Promote Health Aging Among Chronically Ill Geriatrics in a Community
The aim of this study is to evaluate the effect of hydraulic resistance circuit training for elderly people with chronic illness.
- Conditions
- Diabetes, Hypertension, Osteoporosis, Osteoarthritis
- Trial name
- NCT01754415
- Testing
- hydraulic resistance circuit training
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital