Clinical trials: Bone Mass
Scoliosis, Bone Diseases, Metabolic
Improving Low Bone Mass With Vibration Therapy in Adolescent Idiopathic Scoliosis (AIS)
This is a prospective randomized controlled trial investigating the effect of vibration therapy on bone mineral density (BMD) and bone quality in AIS subjects suffering from osteopenia (low bone mass).
- Trial name
- NCT01108211
- Testing
- Vibration Platform
- Where
- China
- Volunteers
- 149 people
- Sponsor
- Chinese University of Hong Kong
Osteoporosis, Sarcopenia
Effect of Creatine Supplementation and Exercise on Bone Health
Osteoporosis is an important health problem, costing the Canadian health care system over $2 billion per year. Loss of bone mineral and bone fragility is especially prevalent in postmenopausal women.
- Trial name
- NCT02047864
- Testing
- Creatine monohydrate
- Where
- 2 sites in Canada
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Hyperparathyroidism; Secondary, Renal
Bone Markers and Bone Density Changes in Hyperperparathyroid Dialysis Patients Under Cinacalcet Treatment
Chronic kidney disease related mineral and bone disorders (CKD-MBDs) and secondary hyperparathyroidism (SHPT) are observed in most patients with chronic kidney disease on dialysis (CKD-5D).
- Trial name
- NCT04637360
- Testing
- Cinacalcet Tablets, calcitriol
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Min-Sheng General Hospital
Alveolar Bone Loss
Osseodensification Versus Motor-Driven Expanders' Techniques for Increasing Bone Density With Simultaneous Implant Placement
The aim of this study was to compare and measure the amount of bone density and ridge width gained with motor driven expanders and densifying burs with simultaneous dental implant placement.
- Trial name
- NCT04609475
- Testing
- Osseodensification technique, Motor driven expanders' technique
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Nourhan M.Aly
Diabetes Complications, Osteoporosis
The Effect of Liraglutide on Bone Turnover, Bone Mass and Bone Cell Function
The purpose of this study is to test whether liraglutide, a drug approved and widely used in the treatment of type 2 diabetes, has an effect on bone mass and bone cell function.
- Trial name
- LIRABONE (NCT02473809)
- Testing
- Liraglutide
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Osteoporosis
Safety and Efficacy of Alendronate (Fosamax) in Children With Osteoporosis
We have previously evaluated the safety and efficacy of Alendronate in 10 patients with juvenile osteoporosis during a 12-month clinical trial.
- Trial name
- NCT00259857
- Testing
- Alendronate
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Medical University of South Carolina
Bone Health
Study of the Effect of a Calcium-rich Diet on Bone Health in Girls
The aim of this experimental study was to test the effect of increasing dietary calcium intake to 1500 mg/day on increases in bone quality in adolescent females.
- Trial name
- Calkids (NCT01058109)
- Testing
- calcium-rich diet, Calcium rich diet
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Creighton University
Bone Mineral Density
Bone Quality by vQCT and HR-pQCT:Translation to Multi-center Clinical Research
Our overarching aim is to set up a procedural, analytic and developmental framework to establish CT of the central and peripheral skeleton as a clinically useful biomarker for skeletal strength in the clinical research and…
- Trial name
- Interscanner (NCT01544660)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Osteoporosis
Calcium and Bone Mass in Young Females
We originally suggested that calcium in the diet is important in determining the amount of bone (bone mass) that builds up in young adults. We are testing the effect of calcium on bone mass in 354 Caucasian (white) girls.
- Trial name
- NCT00000402
- Testing
- Calcium
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Ohio State University
T2DM (Type 2 Diabetes Mellitus), Low-level Laser Therapy
Effect of Low-level Laser Therapy on Type II Controlled Diabetic Patients After Dental Implant Insertion
This study aimed therefore to evaluate bone density (BD) and OPG levels in the peri-implant crevicular fluid (PICF) in lased controlled type II Diabetes Mellitus (T2DM) patients versus non-lased T2DM patients.
- Conditions
- T2DM (Type 2 Diabetes Mellitus), Low-level Laser Therapy, Bone Density Increased
- Trial name
- NCT05279911
- Testing
- low-level laser therapy (LLLT)
- Where
- 5 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Sinai University
Osteoporosis in Post-menopausal Women
A Clinical Study on the Effect of Discontinuing Alendronate in Postmenopausal Women With Osteoporosis After a Treatment Period Without Fractures
The goal of this clinical trial is to study the effects of discontinuation of Alendronate treatment for three years. The participants are postmenopausal women with osteoporosis, who have had a treatment period without fractures.
- Trial name
- ALEXIS (NCT06864130)
- Testing
- Alendronate 70mg weekly
- Where
- 7 sites in Denmark
- Volunteers
- 1,400 people
- Sponsor
- Odense University Hospital
Anterior Cruciate Ligament Rupture
Effects of Preoperative Rehabilitation on Tendon Healing, Bone Mineral Density, and Cartilage After ACLR and Patellar Dislocation
To explore the effect of preoperative exercise rehabilitation on bone mineral density, tendon bone healing, change of cartilage, and gait feature in patients with anterior cruciate ligament rupture.
- Trial name
- NCT05924178
- Testing
- exercise rehablitation, routine treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Bone Mineral Density, Primary Implant Stability
Digital Eye®-Assisted Bone Density Classification and Primary Dental Implant Stability.
Dental implants are used nowadays to replace extracted teeth. They provide a successful substitute for lost teeth. Accurate planning prior to implant placement is very important.
- Conditions
- Bone Mineral Density, Primary Implant Stability, Digital Eye Bone Density Assessment, Site-specific Drilling Protocol
- Trial name
- NCT07899606
- Testing
- R2GATE Digital EYE-Assisted Site-Specific Drilling Protocol, R2GATE® Digital EYE® Implant Planning Software, MEGA ISQ® - Implant Stability Measurement Device
- Where
- Jordan
- Volunteers
- 60 people
- Sponsor
- King Abdullah University Hospital
Osteopenia, Osteoporosis
Time-specific Exercise in Circadian Context
The project aims to explore the mechanisms, by which physical activity can support healthy ageing and decrease the negative impact of ageing on the circadian system, musculoskeletal system and immunity.
- Conditions
- Osteopenia, Osteoporosis, Aging
- Trial name
- CAEx (NCT06746649)
- Testing
- Combined training
- Where
- Slovakia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Comenius University
Bone Density, Body Composition
VITamin D and OmegA-3 TriaL: Effects on Bone Structure and Architecture (VITAL)
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is a randomized clinical trial in 25,871 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or fish oil (1 gram of omega-3 fatty…
- Conditions
- Bone Density, Body Composition, Bone Health
- Trial name
- VITAL (NCT01747447)
- Testing
- omega-3 fatty acids (fish oil), Vitamin D3
- Where
- United States
- Volunteers
- 771 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Osteoporosis, Bone Loss, Age-Related
ONO-5920/YM529 Confirmatory Study in Involutional Osteoporosis Patients
This is a multi-center double-blind parallel-group study in involutional osteoporosis patients to compare the efficacy and safety of monthly oral intermittent formulation ONO-5920/YM529 with its daily formulation.
- Trial name
- NCT00794443
- Testing
- YM529 / ONO-5920
- Where
- 5 sites in Japan
- Volunteers
- 692 people
- Sponsor
- Astellas Pharma Inc
Endometriosis
Efficacy and Safety Study of Elagolix Versus Placebo or Leuprorelin Acetate in Endometriosis
This study is designed to evaluate the safety and beneficial effects of elagolix (NBI-56418) compared to placebo and leuprorelin (an approved endometriosis therapy) over a three month period followed by an additional three months…
- Trial name
- NCT00797225
- Testing
- Leuprorelin Acetate Depot, Elagolix
- Volunteers
- 174 people
- Sponsor
- AbbVie
Acute Lymphoblastic Leukemia, Bone Density Increased
Effects of Exercises on Total Body Health in Children With Acute Lymphoblastic Leukemia
In recent years, the survival of patients has increased with the success of leukemia treatment in children. However, according to the treatment modalities applied, complications such as changes in body composition such as…
- Trial name
- NCT04015882
- Testing
- Exercise therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Postmenopausal Osteoporosis
A Trial Evaluating the Effects of Zoledronic Acid 5 mg Infusion on Bone Mineral Density (BMD) in Postmenopausal Osteoporosis (PMO) Patients Between the Ages of 50 and 65 Years
This study will evaluate the effects of zoledronic acid 5 mg infusion on BMD and biochemical markers of bone in post-menopausal osteoporotic patients aged between 50-65.
- Trial name
- NCT00909961
- Testing
- Zoledronic acid
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- Novartis Pharmaceuticals
Marfan Syndrome
Effects of Personalized Training at Home Combining Endurance and Resistance in Patients Suffering From Marfan Syndrome
Marfan syndrome (MS) is an autosomal dominant genetic disorder caused by a mutation in the fibrillin-1 gene (FBN1) encoding the protein fibrillin-1.
- Trial name
- MARF'HOME (NCT04553094)
- Testing
- Endurance training, Muscle building training
- Where
- France
- Volunteers
- 72 people
- Sponsor
- French Cardiology Society
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