Clinical trials: Bone Regeneration
Furcation Defects
Rosuvastatin Gel With 1:1 Mixture of Platelet-rich Fibrin and Bone Graft in Mandibular Degree II Furcation Defects
Rosuvastatin (RSV) is a new synthetic, second-generation, sulfur-containing, hydrophilic statin, that stimulate bone formation in critical-size cortical bone defects adjacent to titanium implants, when administered locally in…
- Trial name
- NCT02369250
- Testing
- Rosuvastatin, platelet rich fibrin
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Third Molar Extraction
The Safety and Efficacy of Alveolar Bone Defect Repair Induced by Gelatin Sponge-loaded Apoptotic Vesicle Complex
Distal bone loss of the second molar due to extraction of the third molar is one of the most common pathological conditions that results in tooth loss of second molar.
- Trial name
- NCT05971342
- Testing
- Gelatin sponge-loaded apoptotic vesicle complex（Kuaikang®), Gelatin sponge only （Kuaikang®)
- Where
- China
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Fifth Affiliated Hospital of Guangzhou Medical University
Bone Disease, Craniofacial Abnormality
Bone Regeneration Using Bone Marrow Stromal Cells
Deficient or inappropriate healing of bone impacts clinical decision-making and treatment options in orthopedics, oral and maxillofacial surgery, plastic surgery and periodontics.
- Conditions
- Bone Disease, Craniofacial Abnormality, Healthy
- Trial name
- NCT00001391
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Asherman Syndrome
Pre-clinical Endometrial Tissular Renovation Study
The endometrium is a tissue with high capacity of renewal ("self-renewal"). This process is regulated by stem cells. Recent studies have shown that bone marrow-derived stem cells (BMDSCs) contribute to tissues and organs…
- Trial name
- PreENTIRE (NCT03665649)
- Testing
- CD133+ cells isolation
- Where
- Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Igenomix
Dental Implants
Study on Immediate Loading of Immediately Placed Single Implants.
The purpose of this study is to evaluate survival and success rates of dental implants placed with immediate loading protocol in extraction sockets. All patients were monitored for 1 year after implants placement.
- Trial name
- NCT01107600
- Testing
- Immediate implant and socket preservation
- Where
- 2 sites in Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital San Pietro Fatebenefratelli
Bone Regeneration
Assessing the Clinical Efficacy of Bentonite Clay Gel on Bone Regeneration in the Treatment of Intra-bony Defects: A Clinico-radiograph Study
The aim of this study is to evaluate osseous regeneration efficacy of bentonite gel with hydroxyapatite in comparison with hydroxyapatite incase of intrabony defects The test group includes patients with intrabony defects where…
- Trial name
- NCT06439264
- Testing
- bentonite clay gel with hydroxyapatite
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr R Viswa Chandra
Narrow Implant, Dental Implant
Narrow Implants Vs Standard Implants With Simultaneous GBR
NDI represent an advisable treatment option when the mesio-distal space is compromised. In a recent retrospective study with a follow-up of 8 years in which they wanted to evaluate the long-term survival, complications…
- Conditions
- Narrow Implant, Dental Implant, Bone Regeneration
- Trial name
- NCT06168500
- Testing
- Test group, Control group
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Intrabony Periodontal Defect
Effect of Alendronate With β - TCP Bone Substitute in Surgical Therapy of Periodontal Intra-osseous Defects.
The aim of the present study was to evaluate the bone formation potential of 400µg alendronate delivered in β-TCP in the treatment of periodontal intra-osseous defects.
- Trial name
- NCT02795546
- Testing
- Alendronate sodium, beta-tricalcium phosphate bone substitute
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Vitamin D Deficiency, Alveolar Bone Loss
Vit D and Post-extractive Bone Turnover
The aims of the study was to correlate the extent of the dimensional alveolar bone changes after tooth extraction and contextual guided bone regeneration with serum vit D levels in 14 patients.
- Conditions
- Vitamin D Deficiency, Alveolar Bone Loss, Alveolar Bone Resorption
- Trial name
- NCT06412705
- Testing
- Tooth extraction, guided bone regeneration and dental implant
- Where
- Italy
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Studio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo
Bone Regeneration
Prospective, Comparative Assessment of Alveolar Bone Augmentation Using GUIDOR® Membrane in the Bound Edentulous Space
Purpose: The goal of guided bone augmentation is to provide an alveolar ridge of sufficient dimension to permit dental implant placement.
- Trial name
- NCT02387008
- Testing
- GUIDOR® membrane with FDBA, GUIDOR® membrane, Bio-Gide® membrane with FDBA
- Where
- 2 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Periodontitis
RhBMP-2 in Intrabony Defects - A Randomized Controlled Trial
This study evaluated the regenerative potential of rhBMP-2 gel in intrabony defects when compared to sticky bone (control).
- Trial name
- NCT04368650
- Testing
- BMP-2, PRF
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Osteopenia
"VIBES"--Low Magnitude Mechanical Stimulation to Improve Bone Mineral Density
The purpose of this study is to determine if daily low magnitude, high frequency whole body vibration can improve bone density in seniors.
- Trial name
- NCT00396994
- Testing
- Low magnitude mechanical stimulation
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Wound Healing, Bone Regeneration
Fucoidan(Seaweed) Based Gel Around Immediate Implants
The current study is a prospective randomised parallel mouth study to evaluate the effect of Fucoidan gel around immediate implant to assess the wound healing and bone regeneration in comparison to regular implant placement…
- Trial name
- NCT07736287
- Testing
- Fucoidan extracted from F. Vesiculosus, immediate implant placement
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Periapical Abscess
Prospective Clinical Trial of Three Apical Sealing Materials
This prospective comparative randomized clinical trial compares healing and bony regeneration in patients who received 1 of 3 different retrograde filling materials following microsurgical apicoectomies for the treatment of…
- Trial name
- NCT04198298
- Testing
- EndoSequence, ProRoot MTA, Biodentine
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of the Pacific
Alveolar Bone Grafting
E-Polycaprolactone-Containing Membrane in Alveolar Bone Regeneration
This study aimed to evaluate the effectiveness of synthetic polycaprolactone (PCL) bioscaffold membranes used for alveolar augmentation in maxillofacial surgery for increasing the amount of newly formed bone after…
- Trial name
- NCT06627621
- Testing
- Alveolar Ridge Reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- cem üngör
Alveolar Bone Loss
A Clinical Investigation to Evaluate the Healing of Tooth Extraction Sites Filled With BioRestore™
The aim of this study was to evaluate by histology and MSCT scans during a 7-month period, the efficacy of a bioactive glass (Inion BioRestore™) placed in human extraction sockets in the maintenance of alveolar ridge.
- Trial name
- NCT01105026
- Testing
- Alveolar Bone Defect Regeneration Following Tooth Extraction
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Alveolar Bone Loss, Alveolar Ridge Abnormality
Repeated Injection of I PRF and Autogenous Bone Graft for Alveolar Ridge Augmentation
The current st udy's objective was to validate the repeated effect of i PRF with autogenous bone on the of gingival thickness , width a n d volumetric bone changes durig maxillary alveolar augmentation using cone beam computer…
- Trial name
- I-PRF (NCT06711250)
- Testing
- khoury technique, khoury technique with i-PRF injections
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Horizontal Deficiecy in Maxillary Arches
Horizontal Maxillary Ridge Augmentation With Sticky Bone Versus Collagen Membrane GBR
Guided bone regeneration (GBR) using bone graft and barrier membrane is a well-established technique for augmentation of atrophic alveolar ridges.
- Trial name
- NCT03697616
- Testing
- Ridge augmentation with sticky bone and GBR
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Atrophy, Alveolar Bone Grafting
Digital Planning and Clinical Assessment of the Treated Atrophic Posterior Maxilla With a Sinus Lift Procedure: a Cross-sectional Study.
Maxillary posterior area is the most challenging site for dental implant placement. Indeed, complex remodeling processes, resulting in changes of the maxillary sinus and shape of the alveolar ridge will cause difficulties in…
- Conditions
- Alveolar Bone Atrophy, Alveolar Bone Grafting, Peri-Implant Health, Sinus Floor Augmentation
- Trial name
- NCT07526337
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Bone Regeneration
Influence of Bio-Oss Collagen Grafting at Implant Placement on Buccal Bone Volume Regeneration
to validate the capacity of bio-oss collagen (xenograft block+ collagen type I) placed solely without a membrane on a thin (0.5-1.8mm) buccal bone wall after delayed implant placement to regenerate bone volume.
- Trial name
- NCT04338139
- Testing
- bone regeneration
- Where
- Lebanon
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University