Clinical trials: Bone Resorption
Alveolar Bone Loss
Effectiveness in Limiting the Need to Elevate the Maxillary Sinus
The aim of the present study is to evaluate the effectiveness of different alveolar preservation procedures performed at the time of extraction of the first or second upper molar in avoiding a maxillary sinus elevation or at…
- Trial name
- SO-GHI (NCT03357705)
- Testing
- alveolar ridge preservation with synthetic bone, alveolar ridge preservation with bovine collagen
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Alveolar Bone Resorption, Socket Preservation
Effect of Hyaluronic Acid, With Demineralized Tooth Graft, in Socket Preservation, vs Demineralized Tooth Graft Alone.
Many dentists, clinicians and researchers have conducted numerous trials, and put several materials and procedures under the test, in an attempt to preserve vertical and/or horizontal extraction sockets dimensions.
- Conditions
- Alveolar Bone Resorption, Socket Preservation, Bone Resorption, Unrestorable Dentition
- Trial name
- NCT05613075
- Testing
- tooth extraction and socket preservation with demineralized tooth graft, tooth extraction and socket preservation with demineralized tooth graft with hyaluronic acid
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss, Dental Implant Failed
Simultaneous Implant Placement With Vertical and Horizontal Bone Augmentation
The purpose of this study was to report the clinical and radiographical outcomes of using autogenous cortical bone plates combined with sticky allogenic bone graft for augmenting maxillary anterior atrophic combined horizontal…
- Trial name
- NCT06313229
- Testing
- implant placement 6 months after ridge augmentation, implant placement Simultaneously with ridge augmentation
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Lead, Blood, Pregnancy
Dietary Calcium Supplementation to Reduce Blood Lead in Pregnancy
Lead accumulates in bone. During pregnancy, physiologic changes occur prompting bone resorption in order to provide calcium to the growing fetal skeleton also release the lead stored in bone into a pregnant woman's circulation.
- Conditions
- Lead, Blood, Pregnancy, Bone Resorption
- Trial name
- NCT00558623
- Testing
- calcium carbonate
- Where
- Mexico
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Alveolar Bone Loss
Composite Plug Vs D-PTFE Membrane in Socket Preservation
The aim of the current study is to compare the effect socket sealing with flowable resin composite compared to dense polytetrafluoroethylene membrane after filling the extraction site with xenograft particles in terms of soft and…
- Trial name
- NCT06315413
- Testing
- Socket preservation using xenograft and composite plug, Socket preservation using xenograft and intentionally exposed d-PTFE
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss
Autogenous Demineralized Dentin Graft Combined With Injectable PRF + Metronidazole Versus Autogenous Demineralized Dentin Graft Alone for Alveolar Ridge Preservation
The aim of this trial is to compare the effect of autogenous demineralized dentin graft combined with injectable PRF loaded with metronidazole (sticky demineralized tooth releasing metronidazole) versus autogenous demineralized…
- Trial name
- NCT05470673
- Testing
- Alveolar ridge preservation using autogenous demineralized dentin graft combined with injectable PRF loaded with metronidazole, Alveolar ridge preservation using autogenous demineralized dentin graft alone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss
Vitamin D and Periodontitis
Vitamin D has become important for periodontal disease due to play a role in autoimmunity, bone mineral metabolism and inflammation.
- Trial name
- NCT03088488
- Testing
- fasting venous blood samples
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ordu University
Bone Atrophy, Alveolar
Apico-coronal Position of Tissue-level Implants Bone Stability
early marginal bone loss around dental implants may hamper long term prognosis of implant-prosthetic rehabilitation. this study aimed to study the correlation of pico-coronal position of dental implant (from supracrestal, crystal…
- Trial name
- NCT05363306
- Testing
- implant insertion
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Obesity
Relationships Between GLP-2 and Markers of Bone Turnover Following Feeding
This study has been designed to study differences bone turnover in relation to glucagon-like peptide-2 (GLP-2) following feeding in lean and obese premenopausal women.
- Trial name
- GLP-2 (NCT01531907)
- Testing
- Study visit procedures
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Alveolar Bone Loss, Posterior Mandible
Khoury's Bone Shell Technique Versus Titanium-Reinforced Polytetrafluoroethylene for Augmentation of Horizontal Deficiency in Posterior Mandible (Histomorphometry Analysis)
The purpose of the study is the comparison of bone gained histologically from the Bone Shell Khoury's Technique in comparison with the usage of non-resorbable membrane polytetrafluoroethylene and discussing its eligibility for…
- Trial name
- NCT07669792
- Testing
- GBR using Ti based PTFE, Bone Shell Khoury's Technique
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Alveolar Bone Loss
Minimally Invasive Ridge Splitting Versus the Conventional Open Flap Technique
The goal of this clinical trial is to compare implant stability, and crestal bone loss, when using minimal invasive ridge splitting versus convenient open flap technique.
- Trial name
- NCT06329362
- Testing
- Minimally invasive implantation, Open flap procedure for ridge expansion.
- Where
- 2 sites in Egypt, Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Royal College of Surgeons of Edinburgh
Postmenopausal Osteoporosis
Acute Effect of Teriparatide With Bisphosphonate or Denosumab on Bone Resorption
The aim of the study is to assess the relative antiresorptive properties of 2 osteoporosis medications when combined with teriparatide.
- Trial name
- NCT01750086
- Testing
- Teriparatide 40-mcg subcutaneous injection, Denosumab Injection, Alendronate Oral Tablet
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Alveolar Bone Loss, Platelet Rich Plasma
Bone Healing in Immediate Dental Implants
To study the effect of platelet-rich plasma concentrate on marginal bone loss and bone mineral density in immediate implant placement through CBCT.
- Trial name
- NCT04650763
- Testing
- PRP injection, Automated blood cell separator to extract PRP
- Where
- Pakistan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Bone Resorption After Tooth Extraction
3D Printed Scaffold Device for Ridge Preservation After Tooth Extraction
Following tooth extraction, the socket heals naturally with bone in 1 to 2 months. This healing process occurs with substantial reduction of the original height and width of the alveolar ridge.
- Trial name
- NCT03735199
- Testing
- PCL-TCP scaffold, Geistlich Bio-Gide collagen membrane
- Where
- Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Dental Centre, Singapore
Alveolar Bone Resorption
Guided Bone Regeneration in Alveolar Socket
Following tooth extraction, volumetric changes in the soft and hard tissues of the extraction site are expected to occur with considerable resorption of the alveolar bone in both the vertical and the horizontal dimensions.
- Trial name
- GBR_socket (NCT05577663)
- Testing
- Routine treatment of the extraction socket, Socket seal technique by a free gingival graft, Socket seal technique using a synthetic resorbable membrane
- Where
- Greece
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Dimensional Alterations
Dimensional Soft and Hard Tissue Alterations Following Single Tooth Extraction in the Anterior Maxilla - A Prospective Clinical Study
Bone modeling after tooth extraction has a major consequence on implant therapy, in particular in the esthetic zone. In esthetic sites, no tissue loss should occur if an optimal esthetic outcome is expected.
- Trial name
- Alterations (NCT02403700)
- Testing
- Cone beam computed tomography (CBCT)
- Where
- Switzerland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Bern
Alveolar Bone Resorption, Alveolar Ridge Enlargement
Modified Ridge Splitting Technique Using Autogenous Bone Blocks (MRS)
In this clinical study ridge splitting procedures are preformed using autogenous bone blocks. After a 3-month healing, at the time of dental implant placement bone core biopsy samples are harvested.
- Trial name
- MRS (NCT05005858)
- Testing
- Alveolar ridge splitting, Creating osteotomies with piezoelectric device
- Where
- Hungary
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Bone Substitutes, Alveolar Bone Grafting
Bone Augmentation Techniques in the Mandible Posterior Region
This study will compare three methods to rebuild lost bone in the back part of the lower jaw (posterior mandible) before dental implant placement.
- Trial name
- NCT06661447
- Testing
- Cortical Shell Bone Grafting
- Where
- Ecuador
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Atrophic Maxilla, Zygomatic Implants
Computer Guided Placement of Zygomatic Implants in Two Different Approaches
Evaluation of computer guided placement of Zygomatic implants utilizing intra sinus versus extra sinus surgical approach for the reconstruction of atrophic maxilla.
- Trial name
- NCT06129695
- Testing
- Zygomatic implants
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Resorption
Dietary Intake Modifications to Protect Against Changes in Bone Metabolism
Bone loss is not only a well-documented effect of spaceflight on astronauts, but also a condition that affects millions of men and women on Earth each year.
- Trial name
- ProK (NCT01713634)
- Testing
- Preflight, In-flight
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Aeronautics and Space Administration (NASA)