Clinical trials: Bone Resorption
Alveolar Bone Atrophy
Effect of Socket Preservation Procedure on Dimensional Changes of the Ridge, and Its Efficacy.
In this study, the investigators will evaluate the dimensional changes of alveolar bone in the preserved sites in comparison with extraction only conventional healed sockets, as well. 1.
- Trial name
- NCT01268982
- Testing
- socket preservation
- Where
- Iran
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Alveolar Bone Loss
Autogenous Demineralized Dentin Block Graft Versus Autogenous Bone Block Graft for Alveolar Ridge Preservation
The aim of this trial is to compare the effect of autogenous demineralized dentin block graft (ADDBG) versus autogenous bone block graft (ABBG) harvested from maxillary tuberosity on alveolar ridge preservation after extraction…
- Trial name
- NCT05347017
- Testing
- Alveolar ridge preservation using autogenous demineralized dentin block graft, Alveolar ridge preservation using autogenous bone block graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Menopausal Osteoporosis
A Study of Bone Turnover Markers in Post-Menopausal Women With Osteoporosis Treated With Monthly Boniva (Ibandronate)
This study will determine the rapidity of suppression of the bone resorption marker sCTX in post-menopausal women with osteoporosis.Other bone turnover markers will also be evaluated.
- Trial name
- NCT00303485
- Testing
- Vitamin D and calcium supplementation, ibandronate [Bonviva/Boniva]
- Where
- 10 sites in United States, Puerto Rico
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Bone Resorption
Low Speed Drilling Versus Conventional Drilling Technique on Crestal Bone Level in Maxilla.(Group B ) A Randomized Controlled Clinical Trial
20 patients were selected requiring implant placement and divided randomly into two groups (10 in each group) for the study group, starter drill is used to locate the point of insertion as planned then pilot drill is also used to…
- Trial name
- NCT03212820
- Testing
- Drilling at low speed, Drilling at conventional or high speed
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Bone Loss
Evaluation of Peri Implant Bone Loss of Immediately Versus Conventionally Loaded Implants With a Single Prosthesis
The main objective of this prospective, controlled, and randomized clinical study is to evaluate the peri-implant bone loss of immediately loaded versus conventionally loaded implants with a single prosthesis.
- Trial name
- Mpigozzo (NCT02416700)
- Testing
- immediate implant surgery, implant surgery (Straumann®)
- Where
- Brazil
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mônica Nogueira Pigozzo
Bone Resorption
Bone Changes Assessment in Screw-Retained Maxillary Complete Denture With Electric Welded Framework Versus Cast One
comparing bony changes around implants that will be joined by ametal framework either with electric weiling or with the conventional casting metal
- Trial name
- NCT04548258
- Testing
- electric intraoral weilding, casting
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Resorption
Vertical GBR LPRF Block vs. Autogenous Bone With DBBM
split-mouth RCT, 25 months follow up. GBR protocol with LPRF as grafting material in the test group and autogenous bone with DBBM as grafting material in the control group.
- Trial name
- NCT06317090
- Testing
- guided bone regeneration
- Where
- Belgium
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Bone Loss, Alveolar Bone Resorption
Biomaterial Clinical Performance in a Socket Preservation Model
When a dental extraction is performed, sequential cascade of events happens that lead to a modeling and remodeling of the area. This phenomenon leads to bone resorption and consequential volume loss atrophy.
- Trial name
- NCT04789759
- Testing
- Socket Preservation - Bond Apatite synthetic bone substitute, Socket healing - No Filler
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- International Advanced Dentistry, Lisbon
Alveolar Process Atrophy
Ridge Preservation With Provisional Ovoid Pontic
A prospective randomized controlled trial of 30 patients from the Faculty of Dentistry of the UFJF was conducted. It was included patients who presented indication of extraction of premolars, canines or incisors.
- Trial name
- NCT03166475
- Testing
- Surgical procedures
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Juiz de Fora
Alveolar Bone Resorption
Efficiency of Using Osseodensification Protocol
the goal of this clinical trial is to learn if the new osseo-densification technique works to provide enough bone width and quality prior to implant placement in the upper jaw the main question it aims to answer is: Is the use of…
- Trial name
- NCT06426719
- Testing
- Alveolar ridge wideninig via applying osseodensification protocol using densah burs, Alveolar ridge widening via hand osteotomes
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mohamed Magdy Mostafa Shehata
Periodontal Bone Loss
The Use of Chlorhexidine Gel Following EDTA Root Surface Etching as an Adjunctive to Open Flap Debridement in Treating Intra-Bony Defects
SUMMARY Chronic periodontitis is regarded as an inflammatory disease that affects the supporting tissues of teeth which could lead to bone destruction.
- Trial name
- NCT05170932
- Testing
- CHX gel 2 % + 24% EDTA
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Alveolar Bone Resorption
Autogenous Ramus Bone Block Harvesting With Piezosurgery
The aim of this randomized prospective clinical trial was to evaluate the outcome of bone block harvesting from the retromolar region using the Conventional and Piezosurgery Method.
- Trial name
- NCT05548049
- Testing
- Bone harvesting from ramus area with piezosurgery for autogenous bone augmentation, Bone harvesting from ramus area with conventional burs for autogenous bone augmentation
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Marmara University
Bone Loss, Osteoclastic, Bone Loss, Alveolar
Autogenous Mesenchymal Stem Cell Culture-Derived Signalling Molecules as Enhancers of Bone Formation in Bone Grafting
This study aims to evaluate bone formation in grafts in terms of its quality (density), quantity (volume) and maturation obtained with the application of a tissue-engineered bone grafting compound containing concentrated…
- Conditions
- Bone Loss, Osteoclastic, Bone Loss, Alveolar, Alveolar Bone Loss, Alveolar Bone Atrophy
- Trial name
- NCT04998058
- Testing
- Maxillary sinus floor elevation grafting with synthetic bone substitute.
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Alveolar Bone Loss, Tooth Extraction
Platelet Rich Fibrin (PRF) in Socket Preservation Technique
The loss of a tooth or change in its function is lead to a change in alveolar ridge's height and volume. Socket preservation (SP) is a procedure designed to prevent or limit alteration of the post-extraction bone ridge to achieve…
- Trial name
- NCT06173492
- Testing
- Dental extraction, Platelet Rich Fibrin
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Naples
Alveolar Bone Loss
Autogenous Demineralized Dentin Graft Combined With Injectable PRF + Metronidazole Versus Autogenous Demineralized Dentin Graft Combined With Injectable PRF Versus Autogenous Demineralized Dentin Graft Alone for Alveolar Ridge Preservation
The aim of this trial is to compare the effect of autogenous demineralized dentin graft combined with injectable PRF loaded with metronidazole (sticky demineralized tooth releasing metronidazole) versus autogenous demineralized…
- Trial name
- NCT06374784
- Testing
- Alveolar ridge preservation using autogenous demineralized dentin graft combined with injectable PRF loaded with metronidazole, Alveolar ridge preservation using autogenous demineralized dentin graft combined with injectable PRF, Alveolar ridge preservation using autogenous demineralized dentin graft alone
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Diseases, Periodontal Pocket
Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study
The goal of this split-mouth clinical trial is to evaluate the effects of Manuka honey applied into periodontal pockets after initial periodontal therapy (NSPT) in the treatment of stage 3 periodontitis.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontal Bone Loss, Periodontal Attachment Loss
- Trial name
- NCT05631600
- Testing
- Manuka honey
- Where
- Croatia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Edentulous Jaw, Bone Loss, Alveolar
Effects of Different Centrifuged Platelet Concentrates on Bone Remodelling Around Dental Implants
Platelet concentrates obtained from blood have been used as regenerative biomaterials in periodontal surgery. Along with the migration and proliferation of osteogenic cells, platelets accelerate bone regeneration by increasing…
- Conditions
- Edentulous Jaw, Bone Loss, Alveolar, Resorption, Bone
- Trial name
- NCT04851002
- Testing
- Application of concentrated growth factor with dental implants, Application of advanced platelet rich fibrin with dental implants, Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Muhammet Atilgan
Resorption of Mandible
3D Assessment of Mandibular Bone Loss Via STL Superimposition After Complete Denture Occlusal Adjustment
STL registration-based superimposition is an advanced technique for assessing mandibular bone resorption in removable complete denture (RCD) patients.
- Trial name
- NCT06562972
- Testing
- Occlusal equilibration of complete denture using articulating paper, Occlusal equilibration of complete denture using occulosense
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Badr University
Peri-Implantitis, Peri-implant Mucositis
Association Between Smoking Habit and Peri-implant Diseases: a Case Control Study
Although smoking has been proposed as well, as a risk factor/indicator for peri-implantitis, there is currently no conclusive evidence. The current literature confronts the inconclusive evidence of tobacco for a risk factor.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Bone Loss, Alveolar
- Trial name
- NCT04952428
- Testing
- Re-examination visit ("today visit")
- Where
- Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Alveolar Bone Resorption
Evaluation of Socket Shield Technique With Immediate Implant Placement in the Esthetic Zone
The study was conducted on 20 immediate implant placement sites in the anterior maxillary region. In the study group, 10 implants were inserted using socket shield technique, while in control group, 10 implants were inserted…
- Trial name
- NCT05409950
- Testing
- Immediate implant placement using socket shield technique
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Egyptian Russian University