Clinical trials: Bowel Functions
Functional Abdominal Pain, Functional Dyspepsia
Efficacy of Open Label Placebo in Children With FGIDs
This study is aimed at investigating the efficacy of placebo for symptom relief in children with abdominal pain related functional gastrointestinal disorders.
- Conditions
- Functional Abdominal Pain, Functional Dyspepsia, Irritable Bowel Syndrome, Functional Gastrointestinal Disorders
- Trial name
- Placebo (NCT02389998)
- Testing
- Hyoscyamine
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Boston Children's Hospital
Endometriosis
MEdical Versus SUrgical Treatments of Rectal Endometriosis
The purpose of this study is to determine whether, in women with deep endometriosis involving the rectum and not intending to get pregnant, continuous hormonal treatment would be followed by better digestive functional outcomes…
- Trial name
- MESURE (NCT01973816)
- Testing
- Triptoreline 11.25 i.v.; Estradiol 0.5% percutaneous gel;, rectal shaving; rectal disc excision; colorectal resection, Cyproterone acetate 50 mg; estradiol 0.5% percutaneous
- Where
- 11 sites in France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Rouen
Lifestyle (Sedentary Behavior and Physical Activity), Lifestyle Intervention
Healthy Eating and Active Living (HEAL), Exploring Feasibility of a Lifestyle Intervention
Lifestyle interventions combining nutrition, physical activity, and behavioral strategies are increasingly recognized for improving metabolic and psychological health, yet their translation into real-world settings remains…
- Conditions
- Lifestyle (Sedentary Behavior and Physical Activity), Lifestyle Intervention, Lifestyle Modification
- Trial name
- HEAL (NCT07662499)
- Testing
- Multimodal lifestyle intervention (HEAL program)
- Where
- United Arab Emirates
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- New York University Abu Dhabi
Irritable Bowel Syndrome, Gluten Sensitivity
Prevalence of Gluten Sensitivity in Irritable Bowel Syndrome: The First Study in Paediatrics.
Recently a new clinical entity, gluten sensitivity (GS), a form of gluten intolerance in which neither allergic nor autoimmune mechanisms can be identified, has been added to the spectrum of gluten-related disorders.
- Trial name
- GS-IBS (NCT02431585)
- Testing
- gluten
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bari
Intestinal Functional Disorder, Inflammation
Lactiplantibacillus Plantarum PD01 Supplementation Reduces Microplastics and Microplastic-associated Chemicals in Humans
The study attempts to conduct randomized double-blind controlled trials to understand whether daily exposure to microplastics (MPs) can cause potential impacts on human health, explore whether the intake of Lactiplantibacillus…
- Trial name
- NCT07416214
- Testing
- Probiotics (Lactiplantibacillus plantarum PD01)
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Fudan University
Healthy
Resistant Maltodextrin Supplementation: Gastrointestinal Health
Resistant maltodextrin (RMD) is an indigestible water soluble fiber that increases fecal bulk by enhancing growth of specific microbial populations; however the effect of RMD on bifidobacteria and total fecal weight is not clear.
- Trial name
- DEX (NCT02733263)
- Testing
- 15 g RMD, 25 g RMD, 0 g RMD
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Florida
Constipation
A Study to Evaluate the Effects of a Natural Supplement in Adults With Chronic Functional Constipation
Constipation is common in the general population, especially in women and in the elderly. Hard stool is a complaint often associated with constipation, which suggests that stool softening would provide a major benefit in the…
- Trial name
- NCT02073006
- Testing
- Natural Fibre Supplement
- Where
- Ireland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Atlantia Food Clinical Trials
Bladder and Bowel Dysfunction
Bladder and Bowel Dysfunction in Children
Background: Bladder and bowel dysfunction (BBD) is characterized by lower urinary tract symptoms accompanied by bowel complaints. BBD is a common condition in childhood.
- Trial name
- NCT05318365
- Testing
- Polyethylene Glycol 3350, Urotherapy
- Where
- 3 sites in Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Irritable Bowel Syndrome
FMT for Post-infectious IBS
Considering that PI-IBS is brought on by infection and gut microbiota may be associated with the onset of symptoms, the modification of altered gut microbiota with nonabsorbable antibiotics such as rifaximin-α or probiotics is…
- Trial name
- NCT05461833
- Testing
- Fecal transplantation, OTILONII BROMIDUM, multi-strain probiotic
- Where
- 2 sites in Ukraine
- Volunteers
- 59 people
- Sponsor
- Bogomolets National Medical University
Abdominal Pain, Irritable Bowel Syndrome
Pain Processing and Pain Neuroscience Education in Children With Chronic Abdominal Pain
The primary scientific objective of the study entails examining whether altered endogenous pain inhibition is present in children with functional abdominal pain (FAP) and irritable bowel syndrome (IBS) compared with healthy…
- Trial name
- NCT02880332
- Testing
- Usual care, Pain Neuroscience education, Extra care
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Irritable Bowel Syndrome
Traditional Chinese Medicine for Treatment of Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a prevalent condition that adversely affects patient's quality of life and represents a large health care burden globally.
- Trial name
- NCT03135821
- Testing
- TCM
- Where
- Singapore
- Volunteers
- 104 people
- Sponsor
- Singapore General Hospital
Irritable Bowel Syndrome
Effects of Aerobic Exercise and Pain Neuroscience Education in Irritable Bowel Syndrome
Irritable Bowel Syndrome (IBS) is a chronic disorder of gut-brain interaction characterized by abdominal pain and changes in bowel habits.
- Trial name
- NCT07397533
- Testing
- Exercise, Pain Neuroscience Education
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Istinye University
Yogurt Intake, Gastrointestinal Immune Function
Yogurt and GI Health
The purpose of this research is to assess mucosal immune function responses in the gastrointestinal (GI) tract to twice-daily yogurt consumption.
- Conditions
- Yogurt Intake, Gastrointestinal Immune Function, Gut Microbiome, Gut Health
- Trial name
- NCT05931471
- Testing
- Yogurt Intervention
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
CRPS
Complex Regional Pain Syndrome (CRPS) and the Gut-bacteria
The purpose of this study is to investigate, for the first time, whether gut bacteria composition and function of patients with CRPS differ from those of healthy adults.
- Trial name
- NCT05473338
- Testing
- Stool and blood samples, Physical examination, Questionnaires
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Chronic Heart Failure, Chronic Obstructive Pulmonary Disorder
Nutritional and Functional Changes in Heart Failure and COPD
Weight loss commonly occurs in patients with chronic heart failure (CHF) and chronic obstructive pulmonary disorder (COPD), negatively influencing their quality of life, treatment response and survival.
- Trial name
- NCT01787682
- Testing
- BOOST High Protein
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Spinal Cord Injuries, Neurogenic Bowel
Prebiotics for Spinal Cord Injury Patients With Bowel and Bladder Dysfunction
An investigator initiated pilot study: two arm, double blind, placebo controlled, randomized, group of approximately 60 patients with spinal cord injury, and who have evidence of neurogenic bladder.
- Conditions
- Spinal Cord Injuries, Neurogenic Bowel, Bladder Dysfunction
- Trial name
- NCT03987126
- Testing
- Human Milk Oligosaccharides (HMO)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
CHAPLE Disease
A Study to Test the Safety of Pozelimab in Pediatric Participants 1 to 5 Years of Age With a Rare Disease Called CHAPLE (Complement Hyperactivation, Angiopathic Thrombosis, Protein-losing Enteropathy) Disease
This study is researching a drug called pozelimab (called "study drug"). The main aim of this study is to monitor the safety and tolerability of the study drug.
- Trial name
- NCT07142343
- Testing
- Pozelimab
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people
- Sponsor
- Regeneron Pharmaceuticals
Irritable Bowel Syndrome
Lubiprostone Effects on Visceral Pain Sensitivity
The purpose of this research study is to determine how Lubiprostone, a medication used to treat irritable bowel syndrome with constipation predominant symptoms (IBS-C), works to reduce clinical pain.
- Trial name
- NCT01166789
- Testing
- Lubiprostone
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of North Carolina, Chapel Hill
Malnutrition, Colorectal Cancer
Nutrition for Colorectal Cancer Patients and Neutrophil Functions
Hypercatabolism and immune suppression are frequently seen in patients with malignancy. Preoperative nutritional state is an important factor in determining surgical and postoperative complications because the preoperative…
- Trial name
- NCT01831310
- Testing
- Standard (Kabiven), Standard-Glutamine, Standard-Omega 3 fatty acid
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Kocaeli University
Constipation - Functional
Evaluation of Changes in Bowel Movement Frequency Following the Consumption of PHGG Compared to Placebo
Evaluation of Changes in Bowel Movement Frequency Following the Consumption of Partially Hydrolyzed Guar Gum (PHGG) in Adults With Constipation as Compared to Placebo (Typhoon 2)
- Trial name
- TYPHOON-02 (NCT05714410)
- Testing
- PHGG
- Where
- Ireland
- Volunteers
- 160 people
- Sponsor
- Société des Produits Nestlé (SPN)
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.