Clinical trials: Braces
Dental Bonding, Orthodontic Brackets
Segmented Indirect Versus Direct Bracket Bonding
This randomized clinical trial compared two methods of attaching orthodontic brackets to teeth: conventional direct bonding, in which each bracket is placed and bonded individually in the mouth, and a segmented modified indirect…
- Trial name
- NCT07861178
- Testing
- Direct bonding, Segmented modified indirect bonding
- Where
- Saudi Arabia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Dental Caries
The Prevalence of White Spot Lesions During Orthodontic Treatment With Fixed Appliances
This study investigates how often cavities develop on the permanent teeth of patients with braces (orthodontic treatment). The hypothesis is that there is no difference in the number of cavities on the permanent teeth of patients…
- Trial name
- WSLs (NCT04186065)
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Hiroko Nagaoka
Enamel Hypomineralization, Dental
The Effectiveness of Biomimetic Materials in Preventing Enamel Demineralization During Fixed Orthodontic Treatment
This study will be done to evaluate the impact of Biosmalto Impact Action Mousse™ on the development and healing of WSLs in individuals receiving orthodontic treatment.
- Trial name
- NCT05940701
- Testing
- Curasept Biosmalto Mousse and toothpaste, Colgate toothpaste
- Where
- Iraq
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Tooth Movement
Biomarkers of Orthodontic Tooth Movement With Fixed Appliances and Vibration Appliance Therapy
Currently, orthodontic treatment typically lasts approximately 2 years. There are a number of advantages for reducing the duration of treatment, including reducing the potential risk of caries, root resorption and for minimizing…
- Trial name
- NCT02119455
- Testing
- Vibration Device
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UConn Health
Dental Caries, Streptococcus Mutans
Effect of MI Paste Plus™ on Streptococcus Mutans and White Spot Lesions in Fixed Orthodontics
Background This study is part of a doctoral research project at Universidad Cardenal Herrera CEU (Spain), directed by Prof. Santiago Arias de Luxán and conducted by doctoral candidate Shirli Kelmendi within the PhD program in…
- Conditions
- Dental Caries, Streptococcus Mutans, Tooth Demineralization, Orthodontic Appliances, Fixed
- Trial name
- MIPASTEORTHO (NCT07244991)
- Testing
- MI Paste Plus (CPP-ACP with Sodium Fluoride)
- Where
- 2 sites in Albania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Dental Caries
Prevention of Enamel Demineralization by Use of K18-smooth Surface Sealant
This study will evaluate effectiveness of a urethane dimethacrylate (UDMA)-quaternary ammonium methacrylate (K18) resin (UDMA-K18) smooth surface sealant to prevent biofilm attachment to tooth surfaces thereby eliminating the…
- Trial name
- K18 (NCT03306433)
- Testing
- UDMA-K18 smooth surface sealant
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Inflammation Gum, White Spot Lesion
Air-polishing With Erythritol During Orthodontic Tretament
Patients with multi-bracketed fixed orthodontic treatment are at increased risk of developing white spot lesions (WSL) and gingivitis. Various preventive strategies have been examined to prevent the development of WSLs.
- Trial name
- AirPort (NCT05989750)
- Testing
- Ultrasonic scaler, Air-Flow Prophylaxis Master
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Catherine Giannopoulou
Orthodontic Retention
The Effect of Full Versus Partial Coverage Thermoformed Retainers in Dual Retention With a Lower Bonded Retainer, on Periodontal, Orthodontic, and Patient-Reported Outcomes
After braces are removed, teeth may move back toward their original positions. Retainers are used to help keep teeth straight after orthodontic treatment.
- Trial name
- NCT07669129
- Testing
- Partial coverage vivera retainer, Full coverage Vivera retainer
- Where
- Malaysia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Gingival Health
The Effects of Using Water Flosser Versus Interdental Brush on Gingival Health in Patients With Mandibular Bonded Retainer
This randomized controlled trial aimed to investigate and compare the effects of employing a water flosser versus an interdental brush on the gingival health of individuals with mandibular bonded retainers.
- Trial name
- NCT07054203
- Testing
- Water Flosser, Interdental Brush
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Demineralization
Prevention of Enamel Demineralization Using CPP-ACP-NaF Varnish
Sometimes when people wear braces, the combination of dental plaque and diets high in sugar and acids can lead to white spots on the teeth surrounding the braces.
- Trial name
- CPP-ACP (NCT04002232)
- Testing
- CPP-ACP-NaF varnish
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Orthodontic Appliances
Changes in Pulpal Blood Flow Between Conventional and Self-ligating Fixed Orthodontic Brackets During Leveling and Alignment Stage
Evaluate and compare initial changes in PBF between conventional and self-ligating fixed orthodontic brackets during leveling and alignment stage using 0.016" Nickle titanium (NiTi) and 0.016X0.022" NiTi archwires at different…
- Trial name
- NCT03780764
- Testing
- A Pre-adjusted edgewise brackets: 3M Gemini Unitek, 0.022" Roth prescription brackets, Self- ligating brackets: Unitek™ Gemini SL Self-Ligating Brackets, 0.022" Roth prescription brackets
- Where
- Jordan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Canine Retraction
Comparison of Maxillary Canine Retraction Rate Among Conventional (Labial) vs Dual (Simultaneous Labial and Palatal) Force Mechanics Using Labial Fixed Orthodontic Appliances
1. To compare maxillary canine retraction rate among conventional (labial) vs dual (simultaneous labial and palatal) force mechanics using labial fixed orthodontic appliances. 2.
- Trial name
- Dual (NCT07508384)
- Testing
- Dual force application
- Where
- Pakistan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Gingivitis
Effectiveness of Brush DJ App in Improving Oral Hygiene Compliance of Fixed Orthodontic Patients
In this day and age, smartphones are occupying big portions of our lives. Expanding development of mobile applications focusing on delivering behavioral health intervention have intrigued us to know better about their efficacy.
- Trial name
- NCT05853276
- Testing
- Brush DJ app
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IMU University, Malaysia
Orthodontic, Pain
Impact of Photobiomodulation on Pain Associated With Orthodontic Treatment
Orthodontic treatment can cause pain. Research studies have shown that light therapy can help reduce pain that is caused by orthodontic treatment.
- Trial name
- NCT06289595
- Testing
- PBM Ortho device
- Where
- 7 sites in Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- PBM Healing International Limited
Dental Plaque
Clinical Evaluation of the NeoPill Device for Reduction of Oral Bacterial Load in Patients With Fixed Orthodontic Appliances
This study evaluates the effectiveness of the NeoPill oral hygiene device in reducing oral bacterial load in adults wearing fixed orthodontic appliances.
- Trial name
- NCT07355400
- Testing
- NeoPill Oral Hygiene Device
- Where
- Cyprus
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Neofunction d.o.o.
Gingivitis, Dental Plaque
Efficacy of Electric 3D Versus Manual Toothbrushes in Patients With Fixed Orthodontic Appliances
This study evaluates if electric toothbrushes with a 3D action (rotation / oscillation and pulsation) are more effective than manual toothbrushes in removing plaque and reducing gingival inflammation in patients under orthodontic…
- Trial name
- NCT02699931
- Testing
- Electric3D, Manual
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Orthodontics
How Often Should We See Our Orthodontic Patients
Fixed orthodontic braces are routinely used to straighten teeth and correct the bite of individuals. Once the braces are fit, the patient is recalled every few weeks to adjust or tighten the brace.
- Trial name
- NCT02918240
- Testing
- Appointment intervals, fixed orthodontic braces
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King's College London
White Spot Lesion
Evaluation of Enamel Demineralization During Clear Aligner Orthodontic Treatment
Development of white spot lesions (enamel demineralization) will be evaluated quantitatively during clear aligner orthodontic treatment compared to conventional fixed appliances using quantitative light induced fluorescence (QLF)
- Trial name
- NCT04107012
- Testing
- Orthodontic treatment with clear aligner
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Malocclusion
The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances
The aim of this study is to determine efficacy of OrthoPulse photobiomodulation on the rate of tooth movement during alignment for Subjects receiving fixed appliance orthodontic treatment.
- Trial name
- NCT03202355
- Testing
- Fixed Appliance Orthodontic Treatment, OrthoPulse™
- Where
- 3 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Oral Ulcer, Orthodontic Appliances, Fixed
Effectiveness of a Curcumin Mouthwash in Preventing Traumatic Ulcers in Patients With Fixed Orthodontic Appliances
The study is a randomized controlled trial. The participants will be equally allocated into 2 groups to compare clinical effectiveness of curcumin mouthwash in fixed orthodontic patients during the first month of treatment.
- Trial name
- NCT05147376
- Testing
- Curcumin mouthwash
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University