Clinical trials: Brain Activity
Anorexia Nervosa
Impact of Fatty Stimuli on Cerebral Activity in Anorexia Nervosa: a Multi-sensory Approach
Lipid restriction is significant in anorexia nervosa and limits therapeutic management. The multisensory perception of fat is altered, creating an aversion to lipids.
- Trial name
- ANOVERSION (NCT07344831)
- Testing
- MRI examination, Smell and taste capacity testings
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Aging
Modulating Brain Activity to Improve Goal-directed Physical Activity in Older Adults
Although the majority of older adults are aware of the compelling evidence that regular exercise is critical to the maintenance of health into old age, most do not meet recommendations for daily exercise.
- Trial name
- Stim-Fit (NCT04278560)
- Testing
- Transcranial direct current stimulation (tDCS), Behavioral intervention to increase physical activity
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Movement Disorder
Cerebral Activity Related to Primary Motor Stereotypies in Children: An EEG Study.
Background: Motor stereotypies are a movement disorder characterized by involuntary, repetitive, and rhythmic movements. These movements have a predictable pattern and seem purposeful, but they serve no obvious function, tend to…
- Trial name
- NCT01037361
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Aging
Affordable Mobile Robots for the Elderly
This project develops and tests the use of service robots to track health of the elderly over time. The objectives are to develop a low-cost mobile manipulator capable of a limited set of elder- relevant manipulation tasks (e.g.
- Trial name
- NCT02807506
- Testing
- Mobile Service Robot, Survey
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Aging, Music
Brain Imaging and Behavioural Changes Following Cued-movement Training of Finger Sequences in Healthy Older Adults
The goal of this study is to examine changes in the brain, behavior, and personal experience when music is used to guide learning of finger movement sequences (compared to visual stimuli alone) in healthy older adults.
- Conditions
- Aging, Music, Motor Activity, Magnetic Resonance Imaging
- Trial name
- NMSOA (NCT06174740)
- Testing
- Music-cued audiovisual motor training, Visually-cued motor training
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiteit Leiden
Dynamic Balance, Postural Balance
The Effects of Brain Breaks on Dynamic Balance in University Students
The goal of this study is to learn if an online physical activity program called "Brain Breaks" can improve well-being among university students.
- Trial name
- NCT07546747
- Testing
- Brain Breaks Intervention
- Where
- China
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Migraine, Cold
Investigation of the Effect of Cold Application in Migraine
Migraine is a headache that is paroxysmal and can last for hours, sometimes even days due to untreated or ineffective treatment is usually unilateral, throbbing, severe enough to prevent the person's daily life activities, and…
- Conditions
- Migraine, Cold, Relaxation, Exercise
- Trial name
- NCT05454826
- Testing
- Exercise, Cold Application
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Eylül Pınar KISA
Healthy
Normative QEEG/ERP Data for Healthy Volunteers
Many scientific papers have reported that ERP and QEEG biomarkers can be useful in the evaluation of neurological and psychiatric disorders.
- Trial name
- NCT05869032
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Neuronetrix, Inc.
Cerebrovascular Circulation, Magnetic Resonance Imaging
Brain Blood Flow Responses During Exercise
Brain blood flow will be measured during exercise using magnetic resonance imaging.
- Trial name
- NCT05864950
- Testing
- MRI
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
COVID-19 Respiratory Infection
Cardiopulmonary Rehabilitation in Long COVID-19 Patients With Persistent Breathlessness and Fatigue
The objective of this project is to assess the effects of a 2-month cardiopulmonary rehabilitation program on cardiorespiratory fitness in long COVID19 patients.
- Trial name
- COVID-Rehab (NCT05035628)
- Testing
- Cardiopulmonary exercise training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Louis Bherer
Alzheimer Disease, Dementia
MEMORI Corps: Activity-based Companion Care for Dementia
This project adapts a novel activity-based companion care model, the Making Engagement Meaningful through Organized Routine Interaction (MEMORI) Corps intervention, for a virtual delivery format, and then implements the…
- Trial name
- MEMORI Corps (NCT03896711)
- Testing
- MEMORI Corps program, Augmented Waitlist Control
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Difference in Regional Brain Activity
Backward Masking Tasks to Decipher Impaired Input-Output Connections in MS @7T
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system. People with MS frequently suffer from cognitive and visual impairment.
- Trial name
- BIO7 (NCT05377671)
- Testing
- IRM multimodale a ultra-haute camp
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Dementia
Mediterranean Diet, Exercise and Dementia Risk in UK Adults
In cohort studies, a Mediterranean Dietary Pattern (MDP) has been consistently associated with reduced dementia incidence. The efficacy of a MDP to prevent dementia has never been directly demonstrated by RCTs, with existing…
- Trial name
- MedEx-UK (NCT03673722)
- Testing
- Foods consistent with a MDP, Physical Activity, Control
- Where
- 3 sites in United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Perinatal Hypoxia, Dopamine
Measuring Brain Activity of School Age Children
This observational study will investigate whether differences in birth events and oxygen levels during the newborn period affects the brain activity of children during the middle childhood years.
- Conditions
- Perinatal Hypoxia, Dopamine, Neurobehavioral Manifestations
- Trial name
- NCT03407729
- Testing
- Magnetic Resonance Imaging, Cognitive Performance Testing
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Idiopathic Parkinson Disease
Quantification of Dopamine Active Transporter (DAT) in Humans: Validation of a New Radiophamaceutical, the [18F] LBT-999
Idiopathic Parkinson's disease (IPD) is a degenerative disease affecting the dopaminergic system. Clinical symptoms of IPD commonly begin after the loss of at least 40 to 50% of striatal dopaminergic terminals (specially…
- Trial name
- LBT 999 (NCT02393027)
- Testing
- [18F] LBT-999 PET
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Insulin Sensitivity
The Importance of Insulin Action in the Brain for the Immune System During Physical Activity
The goal of this clinical trial is to clarify the interaction of central insulin action and physical activity with the immune system. Therefore, participants will undergo bicycle spiroergometer tests.
- Trial name
- NCT06552130
- Testing
- Spiroergometer test with intranasal insulin spray
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Dementia With Lewy Bodies
Exploration of GCase Activity to Identify a Subpopulation Eligible for a Therapeutic Trial in Dementia With Lewy Bodies
This research focuses on the activity of an enzymatic protein: glucocerebrosidase, in dementia with lewy bodies (DLB). Indeed, the mutation of the GBA gene responsible for a decrease in the activity of glucocerebrosidase is the…
- Trial name
- EGELY (NCT05304195)
- Testing
- Glucocerebrosidase, GBA gene, Macrophage biomarkers
- Where
- France
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mental Health Wellness 1
Acute Effects of Physical Activity On Memory, Cognitive Performance and Brain Activity
The overall aim of the study is to investigate the effects of an acute bout of physical activity on cognitive performance and long-term memory in elementary school children.
- Trial name
- NCT03391505
- Testing
- Small-sided soccer game, Walking soccer game, Rest group watching soccer
- Where
- Denmark
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Cognitive Ability, General
INSIGHT, A Comprehensive, Multidisciplinary Brain Training System
Adaptive reasoning and problem-solving are critical skills that allow for accurate decisions to be made based on varying levels of information.
- Trial name
- INSIGHT (NCT02780739)
- Testing
- Cognitive Training - 48 sessions, Fitness, Active Control
- Where
- United States
- Volunteers
- 521 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Multiple Sclerosis
Nursing Students' Brain/MS Immersive Three-Dimensional Learning Activity
This study compared two educational methods. Participants were assigned to participate in a 360-degree experience or a slideshow presentation. The 360-degree video group included a brain and MS program.
- Trial name
- MS (NCT07538063)
- Testing
- The immersive 360-degree educational video, The slideshow (PowerPoint) educational presentation
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York